• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.2
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• pp.313-323
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• 2017

This study is a descriptive study that investigates the factors that affect the frailty of the elderly in the late period. The data were collected using a questionnaire during the period from 1 to 31 of December 2013. The subjects were 301 elderly people aged 70 years living in M city. The data were analyzed using a $x^2$ test, t-test, and ANOVA with the SPSS Statistics 18.0 program. Hierarchical regression analysis was performed to examine the factors that affect the weakness of elderly people. The results showed that 15.3% of the elderly living at home were frail. The factors that affect the frailty of the elderly were sex (p<0.01), nutritional status (p<0.01), cognition function (p<0.01), ADL (p<0.01), IADL (p<0.05), visual acuity (p<0.05), and chewing discomfort (p<0.05). A higher the degree of frailty was associated with women, poorer nutritional status, higher impairments to perform the daily activities (ADL and IADL), poorer hearing, and more feeling of chewing discomfort. These results can explain the frailty of elderly people over 70 years of age in a local community and the variables of health. The results suggest that the development of a comprehensive program for the elderly with weak physical, emotional, and functional health should be given priority.

• The Korean Journal of Pesticide Science
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• v.10 no.1
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• pp.36-42
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• 2006

For the effective control of pepper anthracnose, in vitro antifungal activities of 13 commercial fungicides were tested on spore germination, mycelial growth, and sporulation of Colletotrichum gloeosporioides, anthracnose fungus. Among them, captan, chlorothalonil, dithianon, fluazinam and folpet completely inhibited the spore germination of C. gloeosporioides at the concentration of 0.8 ${\mu}g/ml$. They were followed by mancozeb and propineb, showing more than 80% inhibition of spore germination at 20 ${\mu}g/ml$. The mycelial growth of C. gloeosporioides was strongly inhibited by fluazinam and nuarimol. Except for nuarimol, most of the fungicides represented more antifungal activity on the spore germination than the mycelial growth of C. gloeosporioides. Azoxystrobin and metominostrobin, Strobilurin fungicides, were only moderately active against the spore germination and the mycelial growth of C. gloeosporioides, but they were effective antisporulant against C. gloeosporioides. From these results, control of pepper anthracnose will have achieved by preventive spray of the commercial fungicides.

• Nutrition Research and Practice
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• v.8 no.3
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• pp.257-266
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• 2014

BACKGROUND/OBJECTIVE: Licorice has been shown to possess cancer chemopreventive effects. However, glycyrrhizin, a major component in licorice, was found to interfere with steroid metabolism and cause edema and hypertension. The roasting process of licorice modifies the chemical composition and converts glycyrrhizin to glycyrrhetinic acid. The purpose of this study was to examine the anti-carcinogenic effects of the ethanol extract of roasted licorice (EERL) and to identify the active compound in EERL. MATERIALS/METHODS: Ethanol and aqueous extracts of roasted and un-roasted licorice were prepared. The active fraction was separated from the methylene chloride (MC)-soluble fraction of EERL and the structure of the purified compound was determined by nuclear magnetic resonance spectroscopy. The anti-carcinogenic effects of licorice extracts and licochalcone A was evaluated using a MTT assay, Western blot, flow cytometry, and two-stage skin carcinogenesis model. RESULTS: EERL was determined to be more potent and efficacious than the ethanol extract of un-roasted licorice in inhibiting the growth of DU145 and MLL prostate cancer cells, as well as HT-29 colon cancer cells. The aqueous extracts of un-roasted and roasted licorice showed minimal effects on cell growth. EERL potently inhibited growth of MCF-7 and MDA-MB-231 breast, B16-F10 melanoma, and A375 and A2058 skin cancer cells, whereas EERL slightly stimulated the growth of normal IEC-6 intestinal epithelial cells and CCD118SK fibroblasts. The MC-soluble fraction was more efficacious than EERL in inhibiting DU145 cell growth. Licochalcone A was isolated from the MC fraction and identified as the active compound of EERL. Both EERL and licochalcone A induced apoptosis of DU145 cells. EERL potently inhibited chemically-induced skin papilloma formation in mice. CONCLUSIONS: Non-polar compounds in EERL exert potent anti-carcinogenic effects, and that roasted rather than un-roasted licorice should be favored as a cancer preventive agent, whether being used as an additive to food or medicine preparations.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.6
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• pp.2680-2689
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• 2012

This study was aimed at finding out the relationship between the level of depression and the recognition and attitude of suicide and the study was conducted by a structured and self-filling questionnaire survey for 1,114 urban area students and 968 rural area students (totaled 2,082) in K city in the central districts of the country from July 1, 2009 to July 31, 2009. The result of the study showed that the more serious the level of depression, the higher the recognition and level of attitude for suicide was. Suicide attitude had a meaningful relationship with the degree of suicide recognition and the level of depression and the level of suicide recognition was closely connected with the level of depression. The result of the analysis of Hierarchial multiple regression showed the meaningfully related factors that affect the level of depression were sex, major, grade, school life satisfaction, fellowship with schoolmates, departing from girl or boyfriends, the lowest bracket of living standard, subjective health, smoking, financial status of household, a quarrel with parents and attitude of suicide. In particular, variables that are related to the condition of family life have high relationship with the level of depression.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.11
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• pp.332-339
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• 2016

This study aimed to investigate the awareness and performance of safety in operating room nurses. There were 161 operating room nurses from eight general hospitals included for analysis in this study. The data were analyzed with t-test, one-way ANOVA, correlation analysis, and Scheffe's test. The results show that their perception of patient safety was 3.33 out of a total of 5 points. Moreover, the score of safety management activity for patients in the operating room was 4.28 out of 5 points. As the perception of patient safety in operating room nurses was significantly correlated with their safety management activities, nurses with higher awareness of patient safety were found to have higher degree of performance of safety management activities. In conclusion, to improve safety management activities, open discussion about patient safety should be encouraged and periodic education regarding patient safety should be implemented for operating room nurses to increase the perception of patient safety.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.43 no.1
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• pp.69-78
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• 2017

Hwangryunhaedoktang (HHT) has been traditionally used as a preventive and therapeutic medicine to treat enervation and diverse chronic diseases. This study was designed to compare the antioxidant, anti-wrinkle and whitening effects of HHT extract and its fermented extract by Leuconostoc mesenteroides (FHHT). FHHT was prepared by inoculation of L. mesenteroides after the extraction procedure with 70% ethanol. HHT and FHHT was investigated via high-performance liquid chromatography (HPLC). Simultaneous qualitative analysis of two bioacitive components, berberine and palmatine. was achieved by comparing their retention times ($t_R$) and UV spectra with those of the standard components. Cell viability test results indicated that both HHT and FHHT were non-toxic. In DPPH radical scavenging ability, $SC_{50}$ values of the FHHT was $68.85{\mu}g/mL$, which is more effective than HHT. Moreover, FHHT showed higher expression in production of procollagen type I than HHT. In nontoxic concentration range, FHHT showed strong melanin production inhibitory effect in ${\alpha}-melanocyte$ stimulating hormone (${\alpha}-MSH$)-stimulated B16F10 cell ($IC_{50}=9.82{\mu}g/mL$). These results suggested that fermented extracts of hwangryunhaedoktang had considerable potential as a cosmetics ingredient with an antioxidant and anti-wrinkle and whitening effects.

• Journal of dental hygiene science
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• v.14 no.4
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• pp.488-494
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• 2014

The purpose of this study is to analyze the association of oral health of the elderly and oral health quality of life. The subjects of this study were 282 participants who received the fluoride application and the scaling service through program targeting elderly people carried out by a public health center located in Gyeongsangbuk-do Province. Data were collected from January 2011 to December 2011. The result of comparing subscale scores of quality of life related to oral health depending on socioeconomic characteristics showed that functional limitation scores were lower as educational level got higher. The result of comparing subscale scores of quality of life related to oral health depending on status of oral health and frequency of tooth brushing showed that quality in functional limitations, physical pain, psychological discomfort, physical disability, psychological disability, social disability and handicap scores were lower as the number of cavities got more. The result of multiple regression analysis to identify the factors affecting the quality of life related to oral health showed that the number of cavities and installation of denture were significant variables. The results of this study showed that there was significant association of oral health status and oral health related quality of life of the elderly. In order to maintain the oral health related quality of life, it is important to keep many number of residual teeth even if a person gets older and to support the installation of dentures if necessary.

• Journal of dental hygiene science
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• v.14 no.2
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• pp.107-113
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• 2014

This study was conducted to evaluate the association between periodontal disease and diabetes mellitus. The final analysis population of this study was composed of 4,830 adults with diabetes mellitus or periodontal disease and aged 19 years or older, based on the third-edition data of the 4th Korea National Health and Nutrition Examination Survey (KNHANES) (in 2009). Diabetic status and potential confounders were used in questionnaire materials and physical examination materials, and the presence of periodontal disease was used in the materials for oral health examination by a dentist. For diabetic status, fasting plasma glucose (FPG) levels <100 mg/dl were subcategorized into normal group and FPG levels ${\geq}100mg/dl$ into impaired fasting glucose group; glycosylated hemoglobin (HbA1c) levels <7% into normal group and HbA1c ${\geq}7%$ into diabetes group, on the basis of the American Diabetes Association. According to the 2009 Korea Health Statistics, the case where the pocket depth is 3 mm or more was defined as periodontal disease. The association between the two diseases was evaluated through $x^2$-test and logistic regression analysis using R-commander 2.14. In impaired fasting glucose group, community periodontal index (CPI) groups 3 to 4 had higher risks for periodontal disease 1.23 times (95% confidence interval, 1.07~1.42) than those of CPI groups CPI 0~2, even after adjustment for several confounders. In addition, periodontal disease and diabetes mellitus showed statistically significant differences depending on age, sex, income level, educational background, smoking status, alcohol consumption, and snack intake. The analyses of the third-edition data of the 4th KNHANES showed that there was a statistically significant association between periodontal disease and diabetes mellitus as examined by means of CPI in this study.

• Journal of Environmental Health Sciences
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• v.37 no.1
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• pp.29-43
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• 2011

The seasonal characteristics of atmospheric particulate matter (PM) were evaluated through the measurement of $PM_{10}$ (particles with an aerodynamic diameter of less than 10 ${\mu}m$) and $PM_{2.5}$ (particles with an aerodynamic diameter of less than 2.5 ${\mu}m$) collected in the downtown area of Iksan city over roughly two weeks in each season of 2004. During the sampling period, 54 samples of $PM_{10}$ and $PM_{2.5}$ were collected and then measured for mass concentrations of PM and its water-soluble inorganic ion species. The concentrations of $PM_{10}$ and $PM_{2.5}$ were highly variable on a daily time scale in all seasons, especially in fall. Annual concentrations of $PM_{10}$ and $PM_{2.5}$ were $54.7{\pm}21.6\;{\mu}g/m^3$ and $34.0{\pm}13.4\;{\mu}g/m^3$, respectively. The daily concentrations of the analyzed ions similarly showed a pronounced variation, although a difference between seasons existed. Among them, $SO_4^{2-}$, $NO_3^-$ and $NH_4^+$ were the most abundant ions in all seasons, contributing up to 32% of $PM_{10}$ and 39% of $PM_{2.5}$. The contribution of $SO_4^{2-}$ and $NO_3^-$ showed a seasonal variation, as $SO_4^{2-}$ was the highest during spring and summer and $NO_3^-$ was the highest during fall and winter. Non-seasalt $SO_4^{2-}$ and $NO_3^-$ were found to exist mainly as neutralized chemical components of $(NH_4)_2SO_4$ and $NH_4NO_3$ due to the high concentration of $NH_4^+$ in PM samples, which were a major form of airborne PM in all seasons. Seasonal characteristics of $PM_{10}$ and $PM_{2.5}$ in Iksan were described in relation to the temporal variations of daily concentration of PM and its inorganic ion species including inter-particle reactions.

• Journal of Korean Public Health Nursing
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• v.9 no.2
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• pp.33-42
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• 1995

The purpose of this study is to identify the smoking patterns and their relevant factors of the public officials who are placed to guide people's way of thinking as conservative middle-income group and thereupon, provide for basic data which can be used to reduce the diseases and death rate caused by smoking in terms of preventive medicine. For this purpose, 170 public officials working for the government agencies located in seoul were surveyed for Jan. 10-Jan. 20, 1995. The results of survey can be analyzed/summarized as follows; 1. In terms of daily smoking frequencies, 50 officials $(29.4\%)$ are driven by stress to smoke. Among these offcials, 250nes $(50.0\%)$ smoke 20-30 times a day. Meanwhile, 22 officials $(12.9\%)$ answered that they smoke for pleasure and comfort, and among them 6 officials $(21.4\%)$ smoke 20-30 times a day. 26 officials $(15.3\%)$ are found to be nicotine­addicted physically or psychologically, and to 10 of them $(35.7\%)$ smoke 20-30 times a day. On the other hand, 10 officials $(5.9\%)$ have habit of smoking and 4 of them $(40.0\%)$ smoke 20-30 times a day. 2. Out of 50 officials $(24.9\%)$ who began smoking on impulse, 44 actually stopped smoking, and the rest 6 officials did not even implement their plan. In view of successful cigarette-stopping, only 8 officials $(15.4\%)$ out of 44 impulse-driven smokers succeeded in stopping cigarettes, while the rest 36 failed all. Meanwhile, out of those 84 officials $(64.6\%)$. Who smoked for reduced stress, 28 ones succeeded, while the rest 56 ones failed. Out of 20 officials who were nicotine-addicted but attempted to stop smoking, only 2 smokers succeeded and the rest 18 were all failures. 3. Factors involving smoking and Their patterns 1) By age group (30's, 40's and 50's), the smoking patterns can be grouped into stress-removing, nocotine-addictive and habitual ones, respectively. 2) By acadeic background, our officials smoke on impulse or due to nocotine addition. 3) The length of career is co-related with nicotine addition. 4) The ownership of house is related with smoking for comfort or less stress. 5) The number of children is related with impulse-driven smoking or smoking for comfort.