• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.13
• /
• pp.5417-5421
• /
• 2014

Objectives: The identification of cutaneous T cell lymphoma (CTCL) biomarkers may serve as a predictor of disease progression and treatment response. The aim of this study was to map potential biomarkers in CTCL plasma. Design and Methods: Plasma metabolic perturbations between CTCL cases and healthy individuals were investigated using metabolomics and ultrahigh performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-QTOF/MS). Results: Principal component analysis (PCA) of the spectra showed clear metabolic changes between the two groups. Thirty six potential biomarkers associated with CTCL were found. Conclusions: Based on PCA, several biomarkers were determined and further identified by LC/MS/MS analysis. All of these could be potential early markers of CTCL. In addition, we established that heparin as a nticoagulant has better pre-treatment results than EDTA with the UHPLC-QTOF/MS appraoch.

• Journal of Korean society of Dental Hygiene
• /
• v.23 no.4
• /
• pp.295-302
• /
• 2023

Objectives: In this study, existing knowledge and needs of childcare teachers for developing oral health education plans for infants and young children were investigated. Methods: From March to April 2023, an online questionnaire survey led to the collection of data from 150 childcare teachers. Data were analyzed using the SPSS 22.0 program. Results: Importance-Performance Analysis (IPA) revealed that importance and knowledge of oral health education, importance of oral health, and prevention of oral diseases were priority areas, and treatment, symptoms, and causes were priority areas that needed improvement . According to the IPA on the importance of and demand for oral health education support, the importance and demand for an educational plan were both high. Expert education based on educational goals, information sharing, educational environment support, evaluation system, and monitoring was low in importance but high in demand. Conclusions: Oral care habits during infancy are important for maintaining oral health throughout life. Oral care practice should be improved by developing an oral health education plan for childcare teachers to implement.

• Journal of Korean Society of Rural Planning
• /
• v.18 no.3
• /
• pp.77-89
• /
• 2012

In 2003, "The National Land Use and Planning Act" (NLUP Act) was enacted unifying two old laws; "The Urban Planning Act" enacted in 1962 and "The National Land Use and Management Act" enacted in 1972. One of main reasons of unifying two acts was to extend urban planning-based development systems to rural areas for preventing uncontrolled urban sprawl in rural areas and enhancing or settlling plan-based land use system in rural areas. This paper is conducted with the following specific objectives: i) to critically review the contents of NLUP Act in terms of rational rural land use planning; ii) to evaluate plan-based land use practices in rural area by NLUP Act; iii) to appraise performance level for prevention against unplanned development activities in rural areas by NLUP Act. To accomplish these objectives, we surveyed actural state of rural land use and development system by the new act in two case study areas. Ansung city in Gyeongi province as an urban sprawl region and Hamyang county in Gyeongnam Province as a remote rural area. Study results ascertained that the new act can not effectively control rural land use and not prevent over-use of agricultural land in the positive and effective ways because of followering three points.

• Journal of Korean society of Dental Hygiene
• /
• v.20 no.3
• /
• pp.387-397
• /
• 2020

Objectives: This study aimed to evaluate the inhibitory effects of probiotics containing Lactobacillus reuteri on Streptococcus mutans and Aggregatibacter actinomycetemcomitans. In addition, the degree of biofilm formation, initial acidity, buffering ability, and acid production performance were measured to confirm the dental caries-inducing ability. Methods: S. mutans (KCTC3065) and A. actinomycetemcomitans (KCTC2581) were used as experimental strains. The number of viable cells, degree of biofilm formation, initial pH, buffering capacity, and production performance were measured for comparing L. reuteri-containing probiotics and Bulgaris. Results: The viability of S. mutans in the groups was reduced in the following order: Bulgaris, probiotics, control. The degree of biofilm formation was significantly higher at 0% and gradually reduced at different concentrations (p<0.01). At 2.5%, the absorbance of the probiotics and Bulgaris groups differed significantly (p<0.01). The acid formation ability differed significantly based on the performance of S. mutans in each product (p<0.05). The absorbance of the probiotics group was significantly lower than that of the Bulgaris group (p<0.01). Conclusions: This study suggests that the use of L. reuteri-containing probiotics as an adjuvant for the prevention and decreasing of oral diseases may reduce their incidence, which can be considered one of the benefits of using probiotics.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
• /
• v.13 no.11
• /
• pp.1165-1173
• /
• 2001

The objectives of this study are to analyze the application of radiant floor cooling and to evaluate the control methods through experiments when the radiant heating system is used for cooling. Through the experiment analysis the control methods such as on/off control, variable flow control and outdoor reset with indoor temperature feedback control are evaluated and compared. The cooling curve (reset ratio) is found for radiant cooling, which shows tole relation between outside air temperature and supply water temperature. Comparison of cooling methods shows that outdoor reset with indoor temperature feedback control is more appropriate than on/off control and variable flow control with regard to prevention of the condensation and thermal comfort.

• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.11
• /
• pp.6783-6790
• /
• 2013

Background: Breast cancer is the commonest type of cancer among women, and in Malaysia 50-60% of the new cases are being detected at late stages. Do age, education level, income, ethnicity, relationship with breast cancer patients and knowledge of breast cancer risk factors influence breast screening practices? This study revealed interesting but significant differences. Objectives: To assess the knowledge of breast cancer risk factors and early detection measures among women in a high risk group. Materials and Methods: A cross sectional survey of one hundred and thirty one women relatives of breast cancer patients was carried out. Participants were selected through purposive sampling, during hospital visits. A self-administered questionnaire was used for data collection. Results: The majority of the respondents (71%) had poor knowledge of the risk factors for breast cancer. Income, relationship with a patient and practise of breast cancer screening predicted performance of mammography, $R^2$=0.467, F=12.568, p<0.0001. Conclusions: The finding shows inadequate knowledge of breast cancer risk factors and poor cancer screening practise among women with family history of breast cancer. Poor knowledge and practise of breast screening are likely to lead to late stage presentation of breast cancer disease. Some important predictors of breast cancer screening behaviour among women with positive family history of breast cancer were identified. An understanding of the strengths and significance of the association between these factors and breast screening behaviour is vital for developing more targeted breast health promotion.

• Journal of Korean society of Dental Hygiene
• /
• v.15 no.1
• /
• pp.11-17
• /
• 2015

Objectives: The purpose of the study is to investigate the relationship between noise awareness, hearing ability, and dental hygiene performance in dental hygienists. Methods: The subjects were 234 dental hygienists in Seoul, Gyeonggi-do, and Incheon. The questionnaire consisted of 3 questions of general characteristics of the subjects, 1 question of noise awareness, 3 questions of hearing ability, 5 questions of dental hygiene performance, 1 question of noise reduction necessity, and 2 questions of noise control. Noise awareness, dental hygiene performance, and noise reduction necessity were measured by Likert 5 scale. Cronbach's alpha was 0.825 in dental hygiene performance reliability. Results: There was a significant difference in noise recognition by age(p<0.01) and working career(p<0.05). Those who pumped up the higher TV volume accounted for 31.6% and 3.0% had hearing impairment in the regular health checkup. 3.4% of the respondents complained of hearing loss, ear fluid, and equilibrium problem diagnosed by the doctors. The relationship between the type of workplace environment and task performance showed a significant difference. Those who work in the dental hospitals had high score of 3.43, while those who work in dental clinics had 3.20(p<0.05). The increased level of noise recognition affected the task performance and it is necessary to reduce the noise level. More try must be focused on the noise exposure prevention. Conclusions: In order to reduce the problems due to noise and improve their quality of life, it is necessary to change the noise recognition in the work place.

• Journal of Environmental Health Sciences
• /
• v.46 no.2
• /
• pp.232-244
• /
• 2020

Objectives: The purpose of this study is to develop a management system for the safe handling of chemicals and related health management based on reporting under the Chemical Control Act (CCA). It is used to search handling information by constructing data linked to the name of companies, chemicals, products, etc. Methods: Due to the differences in submission periods for each reporting regulation of the Chemical Control Act, the data used is as follows: A statistical survey collected 26,222 companies in 2014 and 2016, Pollutant Release Transfer Registers (PRTR) collected 4,234 companies in 2015-2017, performance reports by handlers of hazardous chemical substances collected 14,658 companies in 2016-2018, and declarations for import of toxic chemicals collected 892 companies in 2016-2017. The total information on 36,080 companies is standardized based on company ID, name, business registration number, address, and more. The data were classified into information such as company, chemical, and product name and amounts handled and released, and then extracted according to criteria to establish relationships among classified information. Results: A search service was developed for handling information on chemical substances for reporting data by linking four reporting data: statistical survey, PRTR, performance report by handler of hazardous chemical substances, and declaration for import of toxic chemicals under the CCA. It was composed of five menus to search by regulation type, reporting regulation, companies and chemicals, and system management. Conclusion: It is necessary to use data linked by company, region, and chemical to respond and to prevent chemical accidents. In addition, these items can be utilized to perform handling and safety management of chemicals according to whether regulations under the CCA may be implemented.

• Korean Journal of Health Education and Promotion
• /
• v.29 no.5
• /
• pp.115-123
• /
• 2012

Objectives: Students' life changes substantially as grade increases. It implies that risk factors that trigger students' smoking may not be consistent across grades. Most previous studies on student smoking have considered grade simply a control variable. This study examines which and to what extent risk factors are differently associated with smoking initiation according to grade level among high school students in Korea. Methods: Data from the Korean Youth Risk Behavior Web-based Survey (KYRBWS) conducted by the Korea Centers for Disease Control and Prevention (KCDC) in 2007 and 2008 were analyzed in this study. Results: Among boys, school location, school type and pocket money etc. significantly influence smoking initiation in the first grade than in any other grades, but the strength of the association decreased as grade increases except academic performance. Among girls, most independent variables were associated with smoking initiation in the second grade except school location, pocket money per week and academic performance. Conclusions: Our results suggested that the variables related smoking initiation in Korean high school students were notably different by grade and gender. These findings can serve as the basis of policy recommendations with regard to school efforts to prevent student smoking.

• The Journal of Korean Obstetrics and Gynecology
• /
• v.31 no.3
• /
• pp.79-96
• /
• 2018

Objectives: The objective of this study was to survey the performance of postpartum care and compare the western medicine and Korean medicine according to women's postpartum disease. The purpose of this study was to provide basic data for the prevention and management of postpartum disease. Methods: The subjects were 228 women who experienced postpartum disease. This research was conducted in G city, at outpatient department of western medicine hospital and Korean medicine hospital. The degree of performance of postpartum care was measured on a 4-point scale divided by each area, and was compared in three groups. Results: Postpartum care includes traditional postpartum care and postpartum care in hospitals. The degree of performance of postpartum care means that the higher the score, the better. The traditional postpartum care performance score was 2.35 and the postpartum care performance score at the hospital was 1.63. The results of this study showed that the performance of traditional postpartum care was higher than that of postpartum care administered in hospitals. The perception of traditional postpartum care methods was 'An indispensable postpartum care method for health' (75.9%). The most effective method of postpartum care was 'consolidate in harmony traditional postpartum care and guidance of the medical team' (88.2%). Conclusions: The improvement and satisfaction degree of postpartum care were higher in Korean medicine than in western treatments. Therefore, the most efficient method of postpartum care must be integrated in harmony with the direction of the medical staff and traditional methods of postpartum care.