• Title/Summary/Keyword: Prevention of UTI

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Effectiveness of Short-Course Antibiotic Treatment in Uncomplicated, Non-Bacteremic Pediatric Urinary Tract Infections: A Rapid Systematic Review

  • Han Ho Kim;Young June Choe
    • Pediatric Infection and Vaccine
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    • v.30 no.2
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    • pp.55-61
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    • 2023
  • Purpose: Urinary tract infections (UTIs) pose a significant disease burden in children. This study aims to determine whether a short-course regimen is non-inferior to a standard-course regimen in children with UTIs without complication and presence of bacteremia, and to define, in the optimal way possible, the term "short-course" in this context. Methods: We conducted a rapid systematic review of research up to April 2021 in PubMed, Embase, and Cochrane databases. We included studies that compared clinical outcomes in pediatric UTIs treated with short-course(≤4 days) or standard (≥5-7 days) courses. Results: Our analysis suggests that short-course regimes have equivalent efficacy to standard-course regimens, with similar clinical cure rates and recurrence rates. All 10 studies comparing the clinical cure rates of short- and standard-course regimens reported comparable outcomes. The study evaluating renal scarring indicated no inferiority of short-course regimens compared to standard-course ones. Regarding UTI relapse, 8 out of 10 studies reported no significant difference in outcomes between short- and standard-course regimens. Conclusions: Our results purpose that short-course UTI regimens of 6 days or less are just as effective as standard-term regimens of 7 days or more in terms of infection cure and prevention of recurrence. Considering the equivalent rates of clinical cure and relapse between short- and standard-course regimens, it could be inferred that short-course regimens might be a more optimal strategy for managing pediatric UTIs without increasing the risk of complications.

Technical Application and Analysis for Reduction of Water Loss in Water Distribution Systems (상수도 관망의 유수율 제고 기술의 적용 및 분석)

  • Kim, Ju-Hwan;Lee, Doo-Jin;Bae, Cheol-Ho;Woo, Hyung-Min
    • Proceedings of the Korea Water Resources Association Conference
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    • 2009.05a
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    • pp.260-266
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    • 2009
  • Non-revenue water reduction(NRW) technologies are implemented to evaluate and manage leakages scientifically in water distribution systems under local governments. A development of quantitative leakage indicator by measuring minimum night flow, pressure control policy by installation of PRV(pressure reducing valve) and the establishment of leakage prevention schemes by residual life modeling of deteriorated water pipes are reviewed and studied. Estimation models of allowable leakage are developed by measuring and analyzing minimum night flow at residential and commercial area in Nonsan city, which is suggested from UK water industry and can improve an existing leakage indicator for the evaluation of non-revenue water. Also, pressure control method is applied and analyzed to Uti distribution area in Sacheon city in the operation aspect. As results, $466\;m^3/day$ of leakage can be reduced and it is expected that 113million won of annual cost can be saved. In the part of corrosion velocity and residual life assessment, non-linear prediction models of residual thickness are proposed by assessment of corrosion velocity based on exposure years, soil and water quality etc., since the deteriorated water pipe play a major role to increase leakage. It is expected that collection data and analyzing results can be applied effectively and positively to reduce non-revenue water by accumulating surveying data and verifying the results in the business field of water distribution systems under local governments.

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Comparison of Efficacy of Steroid Oint with Different Potency in Phimosis (생리적 포경 치료를 위한 역가가 다른 스테로이드 연고의 효과 비교)

  • Hwang, In Ok;Lee, Eun Sil;Park, Yong Hoon
    • Clinical and Experimental Pediatrics
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    • v.48 no.6
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    • pp.594-598
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    • 2005
  • Purpose : Phimosis is the inability to retract the foreskin of the penis over the glans of the penis. Even though phimosis is not pathogenic, the presence of phimosis is known to increase the risk of urinary tract infection in infancy. The use of topical steroids has been advocated as a safe and economical alternative to surgical intervention. The purpose of the study was to assess the effectiveness of topical steroids for the treatment of phimosis in young boys. Methods : A total of 53 boys with phimosis were divided into two groups to distinguish between the efficacy of low-potency topical steroid(group 1, 27 cases) and of high-potency topical steroid (group 2, 26 cases). Results : The success rate increased in the process of time. After 6 weeks, the success rate was 21 cases in group 1 and 22 cases in group 2. There was no significant differences in treatment outcomes between the two groups. The age of the boys, the appearance of prepuce prior to treatment, and the presence of previous symptoms, including symptoms of UTI, and ballooning of the prepuce at micturation had no significant difference on treatment outcomes. Conclusion : Topical steroid was effective in treatment of phimosis in boys younger than 4 years old. Although treatment outcomes between low- and high-potency topical steroids were not significantly different, those treated with a high-potency steroid cream showed more fast improvement. Further studies are necessary to assess systemic side effects of steroid treatment, duration of treatment and prevention of genitourinary tract infection in male infants.