• Title/Summary/Keyword: Prevention Control

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Pathological Lesions and Inducible Nitric Oxide Synthase Expressions in the Liver of Mice Experimentally Infected with Clonorchis sinensis

  • Yang, Qing-Li;Shen, Ji-Qing;Xue, Yan;Cheng, Xiao-Bing;Jiang, Zhi-Hua;Yang, Yi-Chao;Chen, Ying-Dan;Zhou, Xiao-Nong
    • Parasites, Hosts and Diseases
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    • v.53 no.6
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    • pp.777-783
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    • 2015
  • The nitric oxide (NO) formation and intrinsic nitrosation may be involved in the possible mechanisms of liver fluke-associated carcinogenesis. We still do not know much about the responses of inducible NO synthase (iNOS) induced by Clonorchis sinensis infection. This study was conducted to explore the pathological lesions and iNOS expressions in the liver of mice with different infection intensity levels of C. sinensis. Extensive periductal inflammatory cell infiltration, bile duct hyperplasia, and fibrosis were commonly observed during the infection. The different pathological responses in liver tissues strongly correlated with the infection intensity of C. sinensis. Massive acute spotty necrosis occurred in the liver parenchyma after a severe infection. The iNOS activity in liver tissues increased, and iNOS-expressing cells with morphological differences were observed after a moderate or severe infection. The iNOS-expressing cells in liver tissues had multiple origins.

Comparative Analysis of Best Available Techniques Reference Documents on the Fertilizer Manufacture between Korea and European Union (비료제조업의 국내와 EU 최적가용기법 기준서 비교·분석)

  • Seo, Kyungae;Kim, Gahee;Kim, Eunseok;Seok, Heejeong;Shin, Sujeong;Kim, Younglan;Kang, Philgoo
    • Journal of Environmental Science International
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    • v.29 no.3
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    • pp.307-318
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    • 2020
  • The integrated permit system is applied to class 1 and 2 atmospheric and water pollutant discharge facilities in 19 sectors. The fertilizer sector should receive a permit for a period of four years, from 2019 to 2023. The purpose of this study is to investigate the differences between the Korean Best Available Techniques (BAT) reference document (K-BREF) and the European Union BAT reference document (EU-BREF) in terms of the process and emission characteristics of fertilizer manufacture. K-BREF is written by focusing on products, whereas EU-BREF is produced on focusing on manufacture process. There are five types of BATs(best available techniques economically achievable) in Korea. These BATs selected mainly to recover and reuse raw meterials and save energy. The number of BATs and BAT-AELs(BAT associated emission level) in K-BREF is smaller than that in EU-BREF. We suggest that BATs and those environmental management parameters in Korea need to further reflect the emission characteristics in the fertilizer sector.

Relationship between Breast Cancer and Levels of Serum Thyroid Hormones and Antibodies: a Meta-analysis

  • Shi, Xin-Zhu;Jin, Xing;Xu, Peng;Shen, Hong-Mei
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.16
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    • pp.6643-6647
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    • 2014
  • The breast and the thyroid are hormone responsive organs that are closely related with changes of endocrine function and glandular disease. An association between thyroid disorders and breast cancer (BC) risk has been suggested, although the results are inconclusive. The purpose of the present study was to summarize evidence supporting a relationship between BC and the level of thyroid hormones and antibodies. The MEDLINE and EMBASE electronic databases were searched for studies published between 2000 and 2014. The pooled effects were presented as weighted mean differences (WMD) with 95% confidence intervals (CI) using fixed or random effect models. We summarized the results of 8 cross-sectional studies with 4, 189 participants. The overall pooled results showed that the levels of $FT_3$ and $FT_4$ were significantly increased in patients with BC (WMD=1.592 pmol/l; 95% CI: 0.15-3.033 and WMD=0.461 ng/dl; 95% CI: 0.015-0.906; p=0.043). The TPOAb level in patients with BC was higher than that in the control group (WMD=81.4 IU/ml; 95% CI: 78.7-84.0; p=0.000). The overall pooled results of the TgAb with random effects analyses showed that the TgAb level was significantly increased in patients with BC (WMD=101.3 IU/ml; 95% CI: 48.7-153.9; p=0.000). The present results indicated that the serum levels of $FT_3$, TPOAb and TgAb are significantly higher in patients with breast cancer than in healthy controls.

Practical Use of Cancer Control Promoters in Municipalities in Japan

  • Yako-Suketomo, Hiroko;Katanoda, Kota;Sobue, Tomotaka;Imai, Hirohisa
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.19
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    • pp.8239-8244
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    • 2014
  • The Cancer Control Act in Japan became effective in 2006. In Ibaraki, Toyama, and Hyogo prefectures, the Cancer Control Promoter (CCP) plan was created to strengthen partnerships for cancer prevention. This study aimed to examine the curre nt status of CCP utilization and analyze relationships with intersectoral collaboration, both within the government and with outside partners. In 2008, we mailed questionnaires to 100 administrators responsible for disease prevention and health promotion in municipal governments of the three prefectures. Ninety-one administrators responded (response rate, 91.0%). We analyzed responses to questions regarding whether or not the municipalities had used CCPs. Items assessing intersectoral collaboration examined municipality characteristics and relationships with outside partners and sectors specializing in areas other than community health. Among 90 administrators with valid data, 33 municipalities (36.7%) used CCPs while 57 (63.3%) did not. The Fisher's exact test revealed that intersectoral collaboration for using CCPs was associated with communication with all of the municipal government sectors not related to health. The present study indicated that CCPs were not consistently used in municipalities. However, we found that intersectoral collaborations, especially within the local government, may be related to the practical use of CCPs. This, in turn, may result in effective cancer control and prevention, as well as improvement in community health.

Prevalence of Enterobius vermicularis among Preschool Children in Gimhae-si, Gyeongsangnam-do, Korea

  • Lee, Sang-Eun;Lee, Jin-Hee;Ju, Jung-Won;Lee, Won-Ja;Cho, Shin-Hyeong
    • Parasites, Hosts and Diseases
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    • v.49 no.2
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    • pp.183-185
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    • 2011
  • The present study was performed to determine the prevalence of Enterobius vermicularis among preschool children in Gimhae-si, Korea. A total of 6,921 preschool children in 76 kindergartens were examined using the cellotape perianal swab method. The overall egg positive rate (EPR) was 10.5%. The EPR in boys was higher than that in girls (adjusted odds ratio (AOR): 1.5, P<0.001), and it was higher in rural than in urban children (AOR: 1.2, P=0.022). The present study confirmed that the prevalence of E. vermicularis infection is fairly high among preschool children in Gimhae-si. Therefore, systematic control and preventive measures should be adopted to reduce morbidity associated with this nematode infection.

Genotype of Toxoplasma gondii from Blood of Stray Cats in Gyeonggi-do, Korea

  • Kim, Hye-Youn;Kim, Yun-Ah;Lee, Ho-Sa;Rhie, Ho-Gun;Cho, Shin-Hyeong;Yu, Jae-Ran;Lee, Sang-Eun
    • Parasites, Hosts and Diseases
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    • v.47 no.4
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    • pp.413-415
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    • 2009
  • Genotyping of Toxoplasma gondii has been performed in 23 PCR positive blood samples from stray cats in Korea. We used 2 separate PCR-restriction fragment length polymorphism (RFLP) patterns of SAG2 gene, amplifying the 5' and 3' ends of the locus. The results revealed that all samples belonged to the type I clonal lineage. Although T. gondii organisms were not isolated from the samples, the results of the present study represent that stray cats with T. gondii infection should be seriously concerned in our environment. Adequate and continuous control programs of stray cats are needed to reduce the risk of transmission of T. gondii as a zoonotic infection threatening the public health.

The Trend and Achievements of Erosion Control Research in Japan (일본(日本)에 있어서의 사방공학연구(砂防工學硏究)의 동향(動向))

  • Woo, Bo-Myeong
    • Journal of Korean Society of Forest Science
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    • v.20 no.1
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    • pp.51-60
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    • 1973
  • The trend and achievments of soil erosion control research in Japan were investigated through observation tours and reference work and following facts were found to be important aspects which should be considered in the soil erosion control research program in Korea. Experiments on forest and water relations, and ground water phenomena at the water source zone in Tokyo University. Studies on land-slides and erosion control dam in Kyoto University. Studies on mud-flow and snow avalanches in Hokkaido University. Studies on sanddune fixation and disaster damage prevention forests in Kyushu University. Studies on forest denudations in Nagoya University. Studies on Greening-works and soil erosion prevention chemicals in Tokyo Agriculture University. Training on planning of erosion control works and prevention of disaster damages in Forest Research Institute. Experiments on soil erosion phenomena and infiltration in Tohoku Branch, FRI. Experiments on erosion and surface stratum failure of steep slopes and their prevention methods in Railway Technical Research Institute.

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Effects of a Cancer Prevention Advertisement on Beliefs and Knowledge about Cancer Prevention

  • Kye, Su Yeon;Yoo, Jisu;Lee, Min Hee;Jun, Jae Kwan
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5793-5800
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    • 2015
  • Background: Outcome-expectation beliefs and knowledge may ultimately influence behavior for cancer prevention. The aims of this study were to measure changes in knowledge and beliefs about cancer prevention before and after viewing a television advertisement and identify the factors affecting receptivity to its messages. Materials and Methods: A one-group pretest-posttest design was used in this study of 1,000 individuals aged 20 to 65 years who were recruited online in November 2014. The outcome variables included cancer prevention beliefs based on the Health Belief Model (five items) and knowledge about risk factors for cancer (seven items). Results: Perceived susceptibility, perceived benefits, and self-efficacy increased significantly and their perceived severity and perceived barriers decreased significantly, after participants viewed the television advertisement. Correct responses to questions about risk factors also increased significantly, except for smoking. The main factors affecting changes in the outcome variables were age, interest in cancer prevention, social network, satisfaction with the ad, and pretest scores. Conclusions: Television advertisements with positive frameworks can be an efficient channel of improving beliefs and knowledge about cancer prevention in a short period. The continuous development of intervention materials that consider the demographics, needs, and satisfaction of the target group will be necessary for future studies.

A Study to Verify the Effectiveness of Suicide Prevention Education Using "Life Charger" for the Elderly (노인 「생명충전기」을 활용한 자살예방교육의 효과성 검증 연구)

  • Jong-Hun Lee;Kwang-Za Yu;Tae-Hee Park;Jeong-Min Kim
    • Journal of The Korean Society of Integrative Medicine
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    • v.12 no.2
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    • pp.167-176
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    • 2024
  • Purpose: This study aimed to verify the effectiveness of suicide prevention education using the "Life Charger" program for older adults. Methods: This study conducted the "Life Charger"suicide prevention education with 95 older adults in the experimental group. Participants were recruited from a senior welfare center and a senior citizen center in D metropolitan city, and their attitudes toward suicide and sense of competence in providing help before and after the education were investigated. While no measures were taken for the control group, their attitudes toward suicide and help-giving competence were surveyed during the same period. Statistics were analyzed using SPSS 23.0, demographic variables of the experimental and control groups were calculated as percentiles, and Chi-square analysis and paired-sample t-test were performed to verify the homogeneity of the experimental and control groups. Results: To verify the effectiveness of the "Life Charger"suicide prevention education, the effectiveness of attitude toward suicide before and after the education was verified. The experimental group showed a significantly higher level (t=-6.34, p<.000). Their competence in providing help was also at a significantly higher level (t=-10.20, p<.000). Upon verifying the effectiveness of the program, the experimental group's attitude toward suicide was found to be significantly higher; however, the control group showed no change in attitude toward suicide and competence in providing help. Conclusion: This study verified that the "Life Charger"suicide prevention education for older adults was effective in increasing attitudes toward suicide and sense of competence in providing help. To increase the effectiveness of suicide prevention education for older adults, follow-up research should determine whether there are any actual changes after the training, and attitudes toward suicide and help-providing competence should be increase d through universal and repetitive education to prevent suicide among older adults.