• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.19 no.5
• /
• pp.444-450
• /
• 2018

The purpose of this study was to determine the effectiveness of nutritional intervention for modifying the dietary behavior of breast cancer patients. The study was conducted at Gangnam Severance Hospital from December 2015 to May 2016. The subjects of this study were 30 female breast cancer patients. To conduct this study, dietary behaviors and weight changes were measured, and frequency of exercise, alcohol drinking, and use of supplements were investigated. The results are summarized as follows: Average age and rate of monthly weight loss were $54.3{\pm}9.3years$ and $1.4{\pm}3.5%$, respectively. After nutritional intervention, dietary behavior modification score increased from $2.00{\pm}0.45points$ to $2.76{\pm}0.18points$ out of 3 (p<0.001). After intervention, the proportion of alcohol drinkers among patients decreased from 20% to 0%, and that of patients who exercise frequently increased from 53% to 97%. The percentage of supplement users decreased from 40% to 20%. In consideration of the above results, nutritional intervention and dietary behavior modification for breast cancer patients are very important to prevent recurrence of breast cancer.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.19 no.7
• /
• pp.493-503
• /
• 2018

Recently, as living standards have improved, many people are becoming more interested in health, and self-training is increasing through exercise to prevent and manage pre-illness. In general, an imbalance of muscles causes asymmetry of posture, which can cause various diseases by accompanying an adjustment force, circulation action, displacement of internal organs, etc.. In this study, the development of fitness software that can be self - training among smart wears has attracted considerable attention in recent years. In this study, a technology was proposed for the commercialization of self - trainer fitness wear by a simulation through Android - based applications. Self - trainer fitness software was developed by combining a conductive polymer, fashion design, sewing, and electric and electronic technology to monitor the unbalance of the muscles during exercise and make smart wear that can calibrate the asymmetry by oneself. In particular, a polymer sensor was fabricated by deriving the optimal MWCNT concentration, and the electrode signal was collected by attaching the electrode to the optimal position, where the electrode signal line using the conductive fiber was designed and attached to collect the signal. A signal module that converts the bio-signals collected through electrical signal conversion and transmits them using Bluetooth communication was designed and manufactured. Self-trainer fitness software that can be commercialized was developed by combining noise cancellation with Android-based self-training application using a software algorithm method.

• Journal of Nutrition and Health
• /
• v.27 no.10
• /
• pp.1025-1036
• /
• 1994

This study was designed to investigate the effects of Ca and/or vitamin D supplementation for 53 weeks on bone metabolism in postmenopausal women. The subjects were healthy 18 women aged from 59 to 69 years old. They were divided into three groups : placebo, Ca(1000mg/day) supplementation and Ca(1000mg/day) with vitamin D(12.5$\mu\textrm{g}$/day) supplementation. During the experimental periods except for metabolic studies, the subjects ate their usual diets and the use of drugs as well as excessive exercise was prohibited. Metabolic studies were conducted in the 1st week and in the 53rd week of the experimental periods. The subjects ate experimental diets which consisted of 1787.3kcal, 69.6g of protein, 561.5mg of Ca and 1078.6mg of P daily during both of the metabolic study periods. The results were summarized as follows; 1) Bone density of the second lumbar spine and trochanter measured after treatment decreased significantly in control group as compared with pre-experimental level(p<0.05). On the contrary, bone density of femoral neck and Ward's triangle in Ca group and the second lumbar spine in Ca.Vit D group increased significantly after treatment. 2) Serum PTH and calcitonin levels did not show any significant differences among groups before and after treatment. But serum PTH level increased significantly in all groups after treatment(P<0.05). 3) Serum Ca and P levels did not show any significant differences among groups before and after treatment. But serum Ca level increased significantly in all groups after treatment (P<0.05) and serum P level decreased significantly in Ca.Vit D group after treatment(P<0.05). 4) Mean 24-hours fecal Ca excretion of Ca group was the highest in the 1st week of treatment(P<0.01), and that of control group was the lowest in the 53rd week of treatment(P<0.01). Fecal Ca excretion increased significantly in control and Ca.Vit D group in the 53rd week of treatment(P<0.05). Urinary Ca excretion did not show any significant differences among groups in the 1st and 53rd week of treatment, but that of Ca.Vit D group was the highest the 1st week of treatment(P<0.01). In the 53rd week of treatment Ca and Ca.Vit D group showed positive Ca balance, but control group showed negative Ca balance. The above results showed that it will be difficult to prevent degenerative bone loss without Ca and/or vitamin D supplementation in postmenopausal women eating Korean usual diets.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.12 no.6
• /
• pp.2629-2635
• /
• 2011

This study carried out questionnaire survey and experiment on oral hygiene effects according to the actual condition of using oral care products and the amount of toothpaste used targeting 40 freshmen and sophomores in dental hygienics in some universities from November 8, 2010 to November 26. The collected data was analyzed by using SPSS WIN 15.0 program. The following conclusions were obtained. 1. The result of actual condition of toothbrushing is as follows. As the answer of a question about whether or not toothbrushing after every meal at ordinary times, the largest was 47.5% of being average. The occasion of toothbrushing before going to bed at ordinary times was the largest with 47.5%. The daily toothbrushing frequency was 3 times mostly and the general toothbrushing method at ordinary times was a rolling method. The frequency of exchanging toothbrushes for the past 1 year was 3 times, which is the largest with 45.0%. 2. As a result of the actual condition of using oral care products, the majority of students don't use electric toothbrush, interdental brush, or mouth-rinse except dental floss. Accordingly, there need to be education and promotion with diverse methods so that a patient oneself can prevent oral disease by selecting and using oral care products that are proper for each individual. Also, it was indicated that there is no big difference in oral hygiene effects depending on the amount of toothpaste used. Thus, to avoid wasting toothpaste, we need to educate and promote to use the amount of toothpaste under 0.3g.

• Journal of Microbiology and Biotechnology
• /
• v.28 no.4
• /
• pp.551-560
• /
• 2018

Bellflower root (Platycodon grandiflorum), which belongs to the Campanulaceae family, is a perennial grass that grows naturally in Korea, northeastern China, and Japan. Bellflower is widely consumed as both food and medicine owing to its high nutritional value and potential therapeutic effects. Since foodborne disease outbreaks often come from vegetables, understanding the public health risk of microorganisms on fresh vegetables is pivotal to predict and prevent foodborne disease outbreaks. We investigated the microbial communities on the bellflower root (n = 10). 16S rRNA gene amplicon sequencing targeting the V6-V9 regions of 16S rRNA genes was conducted via the 454-Titanium platform. The sequence quality was checked and phylogenetic assessments were performed using the RDP classifier implemented in QIIME with a bootstrap cutoff of 80%. Principal coordinate analysis was performed using the weighted Fast UniFrac distance. The average number of sequence reads generated per sample was 67,192 sequences. At the phylum level, bacterial communities from the bellflower root were composed primarily of Proteobacteria, Firmicutes, and Actinobacteria in March and September samples. Genera Serratia, Pseudomonas, and Pantoea comprised more than 54% of the total bellflower root bacteria. Principal coordinate analysis plots demonstrated that the microbial community of bellflower root in March samples was different from those in September samples. Potential pathogenic genera, such as Pantoea, were detected in bellflower root samples. Even though further studies will be required to determine if these species are associated with foodborne illness, our results indicate that the 16S rRNA gene-based sequencing approach can be used to detect pathogenic bacteria on fresh vegetables.

• The Journal of Korean Medicine
• /
• v.41 no.2
• /
• pp.58-79
• /
• 2020

Objectives: The purpose of this study is to predict the weight loss by applying machine learning using real-world clinical data from overweight and obese adults on weight loss program in 4 Korean Medicine obesity clinics. Methods: From January, 2017 to May, 2019, we collected data from overweight and obese adults (BMI≥23 kg/m2) who registered for a 3-month Gamitaeeumjowi-tang prescription program. Predictive analysis was conducted at the time of three prescriptions, and the expected reduced rate and reduced weight at the next order of prescription were predicted as binary classification (classification benchmark: highest quartile, median, lowest quartile). For the median, further analysis was conducted after using the variable selection method. The data set for each analysis was 25,988 in the first, 6,304 in the second, and 833 in the third. 5-fold cross validation was used to prevent overfitting. Results: Prediction accuracy was increased from 1^st to 2^nd and 3^rd analysis. After selecting the variables based on the median, artificial neural network showed the highest accuracy in 1^st (54.69%), 2^nd (73.52%), and 3^rd (81.88%) prediction analysis based on reduced rate. The prediction performance was additionally confirmed through AUC, Random Forest showed the highest in 1^st (0.640), 2^nd (0.816), and 3^rd (0.939) prediction analysis based on reduced weight. Conclusions: The prediction of weight loss by applying machine learning showed that the accuracy was improved by using the initial weight loss information. There is a possibility that it can be used to screen patients who need intensive intervention when expected weight loss is low.

• Journal of Korean Ophthalmic Optics Society
• /
• v.18 no.4
• /
• pp.373-383
• /
• 2013

Purpose: In this study, we analyzed refractive power of school children in low income family. Methods: We have done a comparative analysis with 112 subjects of low-income of 17 elementary schools in the Yeongcheon area and low-income children less than -6 D of refractive errors from the Korean National Health and Nutrition Examination Survey Report 2010. Results: Spherical equivalent (SE) with low-income group of nation was -1.99 D for right eye and -1.81 D for left eye, while high income group of nation showed -1.26 D and -1.21 D for right eye and left eye respectively. The SE with low income group in Yeongcheon area was -1.85 D for right eye and -1.81 D for left eye. The SE with orphan was -2.75 D and -2.42 D. Single parent family was -2.10 D and -1.96 D, and two parent family was -1.75 D and -1.73. Conclusions: The lack of attention to children eye care may be one of cause for myopia, so the role of the parents and teacher is very important. However, limited role of parents to children due to low income, it is necessary to provide an institutional strategy and social interest to prevent children vision' in low income family.

• Journal of Nutrition and Health
• /
• v.31 no.9
• /
• pp.1446-1456
• /
• 1998

Bones are important parts in sustaining the shape of the body, but they are also metabolic organs which undergo bone remodeling by constant bone resorption and formation. Osteoporosis, the typical metabolic bone disease, is characterized by a reduction in bone mineral density (BMD). Women more than men are at risk fir osteoporosis-related fractures, especially in the lumbar spine, wrist, and hip region. Risk of fracture depends on one's BMD, which open determined by the peak bone mass value achieved at skeletal maturity and followed by subsequent age-and menopause-related bone loss. Genetic and environmental factors are known to play a key role in bone metabolism and diet is considered as one of the important environmental factors. The purpose of the present study was to assess the status of BMD and bone mineral content(BMC) to clarify the relationships between dietary intakes and the risk of osteoporosis in adult women in Taegu. Subjects were 130 healthy females in between 20 and 69 years of age. BMD and BMC of the lumbar spine(venebrae L2-4) of the subjects were measured by dual energy X-ray absorptiometry. The average age of the subjects was 47.4${\pm}$11.7 years old, the average weight was 57.2${\pm}$8.4kg, the average age of menarche was 16.6${\pm}$1.9 years old and the average age of menopause was 48.4${\pm}$5.3 years old. The nutrient intakes of the subjects measured by the convenient method were generally lower than the level of RDA. The result of nutrient intake assessed has shown that the average energy intake was 1701${\pm}$316kca1 which is 85.1% of the RDA and the average calcium intake was 485.4${\pm}$172.3mg which is 69.3% of the RDA. The intakes of protein, vitamin A, vitamin B$_1$, niacin were greater than the RDA, whereas the remaining nutrient intakes were lower than the RDA. The average BMD of the subjects was shown to be 1.06${\pm}$1.09g/$\textrm{cm}^2$. The highest BMD of 1.24${\pm}$0.14g/$\textrm{cm}^2$ was noticed in the subjects of 30s compared to 20s, 40s, 50s, 60s. The BMD values were compared by the relative body weight(R3W) of the menopause subjects, and it was found that the underweight group had significant lower BMB while the rest of the groups did not have any differences in BMD. The most strongly correlated nutrient with BMD among the menopause subjects appeared to be calcium. The women whose Ca intakes were higher than 500mg showed the significantly higher BMD than those with Ca intakes lower than 500mg. This study suggests that the most effective way to prevent osteoporosis and to reduce the incidences of fractures seems to be minimizing bone loss through the adequate intake of calcium as well as avoiding underweight, especially in menopausal women. (Korean J Nutrition 31(9) . 1446-1456, 1998)

• The Journal of the Korea Contents Association
• /
• v.15 no.9
• /
• pp.223-232
• /
• 2015

This study has analyzed the factors that influence the safety consciousness of elderly drivers. To achieve this, 307 elderly who drives commercial and non-commercial in Daejeon, Sejong, Chungnam and Chungbuk area were selected as study subjects. For the data analysis, PASW Statistics 18.0 was used. The main results of this study are as follows. The level of safety consciousness of commercial and non-commercial drivers were 6.49 and 6.93 respectively showing that drivers of non-commercial were significantly higher. Second, the factors that influence the safety consciousness were shown to be significantly different for each group. The factors that influence the safety consciousness of commercial drivers were shown in the order of safety-seeking motivation, economic status, daily driving hours, sensation-seeking disposition. The factors that influence the safety consciousness of non-commercial drivers were shown in the order of safety-seeking motivation, health status, whether or not the accident was experienced, sensation-seeking disposition. Based on these results, several ways were suggested to improve the safety consciousness of elderly drivers and prevent the traffic accidents.

• Journal of Microbiology and Biotechnology
• /
• v.20 no.2
• /
• pp.438-445
• /
• 2010

The immunomodulatory effects of Aureohasidium pullulans SM-2001 exopolymers containing $\beta$-1,3/1,6-glucan were evaluated in cyclophosphamide (CPA)-treated mice. To induce immunosuppression, 150 and 110 mg/kg of CPA were intraperitoneally injected 3 days and 1 day, respectively, before beginning administration of the test material. Exopolymers were delivered subcutaneously or orally, four times, in a volume of 10 ml/kg at 12-h intervals beginning 24 h after the second CPA treatment. Changes in thymus and spleen weights, splenic amounts of tumor necrosis factor (TNF)-$\alpha$, interleukin (IL)-$1{\beta}$, and IL-10, and numbers of CD3+, CD4+, CD8+, and TNF-$\alpha+$ thymus and spleen cells were monitored in CPA-treated mice. As a result of CPA treatment, dramatic decreases in the number of CD3+, CD4+, CD8+, and TNF-$\alpha+$ cells were detected in the thymus and spleen, along with decreases in thymus and spleen weights. In addition, splenic TNF-$\alpha$, IL-$1{\beta}$, and IL-10 contents were also decreased on observation with flow cytometry. However, oral and subcutaneous treatments with exopolymers effectively reduced the immunosuppressive changes induced by CPA. Therefore, it is concluded that exopolymers of A. pullulans SM-2001 can effectively prevent immunosuppression through, at least partially, the recruitment of T cells and TNF-$\alpha+$ cells or enhancement of their activity, and can provide an effective component of prevention or treatment regimens for immunosuppression related to cancer, sepsis, and high-dose chemotherapy or radiotherapy.