• 한국임상수의학회지
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• 제30권6호
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• pp.459-463
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• 2013

본 연구는 Lactobacillus plantarum (L. plantarum)과 Bacillus subtilis (B. subtilis)의 합제 (LB)를 이유자돈에 경구 투여하여, 면역반응, 설사발생 그리고 분변 중 균수변화 등에 미치는 효과를 평가하기 위해 수행하였다. 28일령의 이유자돈 100두를 대상으로 군 당 20두씩 5개 군 (NC, 항생제와 LB 무투여; PC, 0.03% chlortetracycline 투여; LB 1, LB 0.5 kg/ton feed; LB 2, LB 1.0 kg/ton feed; LB 3, LB 2.0 kg/ton feed)으로 나누어, 4주 동안 LB를 투여하면서, 1주일 간격으로 분변지수를 산출하여 군별로 기록하였으며, 투여 종료 후, 혈액 및 분변을 채취하여, 혈액시료로부터 IgG와 IFN-${\gamma}$를 분석하였고, 분변시료로부터 lactic acid bacteria (LAB)와 Enterobacteriaceae (ENT)의 수를 확인하였다. LB 투약 2주째부터, LB 2와 LB 3의 설사지수는 NC에 비해 통계적으로 유의성 있게 감소하였으며 (P<0.05), IgG와 IFN-${\gamma}$의 농도도 NC에 비해 통계적으로 유의성 있게 증가하였다(P<0.05). 또한, LB 2와 LB 3의 LAB와 ENT 수는 NC과 PC에 비해 통계적으로 유의성 있게 변화하는 결과를 나타내었다(P<0.05). 이상의 결과로부터, LB는 강력한 항생제 대체제로서 자돈 설사예방에 사용될 수 있을 것으로 사료된다.

• 한국의료질향상학회지
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• 제7권1호
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• pp.72-89
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• 2000

Background : Various types of protective footwear have been used to minimize bacterial contamination in operating rooms. In recent years, debate has arisen concerning the need for use of such protective footwear. This study was designed to provide useful data about choosing shoes most suitable for the surgical environment. Methods : Between November, 1999 and January, 2000, we performed this experimental study by comparing effect of three types of shoes (i.e., disposable shoescover, operating room-restricted shoes, and ordinary shoes) on bacterial contamination of operating rooms equipped with two different ventilation systems (i.e., high air-change, low air-change) respectively. Data were collected during two- hour sham operations in which subjects and their activities were strictly standardized. Bacterial flora were sampled from the study area floor and air colony counts were measured. Results : In experiments involving high air-change ventilation system, there was a significant difference of floor contamination between three types of shoes, but no difference of air contamination. Under low air-change system, there was a significant difference of both floor and air contamination between three types of shoes. Conclusion : The results show that protective footwear would be unnecessary in the operating room with high air-change ventilation system, but it is important to choose suitable shoes carefully under low air-change system. Therefore, the use of outdoor shoes can be considered under high air-change system, but it would seem sensible to apply their first use in less bloody operations at the day surgery center or out-patient department to prevent transfer of body fluid into the outside environment.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제22권3호
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• pp.162-168
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• 2011

Objectives: Alcohol problems of parents have an influence on not only their psychological problems but also on their children's psychosocial adaptation. The purpose of this study was to compare the emotional and behavioral problems, including school bullying and social skills, between children of alcoholics (COAs) and children of non-alcoholics (non-COAs). Methods: We recruited $4^{th}$ grade children (n=741) from 7 primary schools in Seoul and their parents as subjects. The self-rated psychiatric symptoms were assessed with the Korean version of the Children of Alcoholics Screening Test (CAST-K), the Children's Depression Inventory (CDI), the Rosenberg's Self-esteem Scale (RSES), the School Bullying Scale, the Social Skill Rating Scale and the Korean version of Alcohol Expectancy Questionnaire-Adolescent (AEQ-A). The Attention-deficit Hyperactivity Disorder Rating Scale-IV (ARS) was completed by the parents. Results: 518 children were non-COAs and 223 were COAs. The COAs showed higher CDI and ARS-IV scores and lower RSES scores than the non-COAs. Especially, the COAs also showed higher school bullying scale scores and lower cooperative scale scores on the social skill rating scales. But there was no difference of alcohol expectancy between the COAs and non-COAs. Conclusion: It was plausible that the COAs had more behavioral & psychosocial problems than the non-COAs among the school aged children. It is important to identify and intervene to solve the problems of peer relationships of school age COAs in order to prevent victimization by bullying and to improve psychosocial adaptation.

• 한국산학기술학회논문지
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• 제18권9호
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• pp.258-266
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• 2017

본 연구는 제6기(2013-2015년) 국민건강영양조사 자료를 이용하여 만12세 이상 19세 미만 청소년의 음주행태와 대사증후군의 관련성을 파악하고자 시도되었다. 청소년의 음주행태와 대사증후군 위험요인들과의 상관관계를 확인하기 위해 Multivariate logistic regression을 이용하여 분석하였다. 대상자는 총 1,698명으로 남자 901명, 여자 797명이었다. 남자 청소년의 경우 최근 1년간 음주빈도와 혈중 중성지방에 유의한 상관관계가 나타났다(p for trend=0.03). 한 번에 마시는 음주량이 5잔 이상일 경우 고중성지방혈증이 나타날 위험성이 유의하게 높아지는 것으로 나타났다(OR 2.28, 95% CI 1.12-4.66, p=0.02). 여자 청소년에서 최근 1년간 음주빈도와 혈중 고밀도지단백 콜레스테롤 수치 사이에 유의한 상관관계가 나타났다(p for trend=0.01). 남자 청소년에서 음주빈도와 음주량이 대사증후군의 위험인자인 혈중 중성지방 증가와 관련성이 나타났다. 이는 청소년 음주가 성인기의 대사증후군으로 발전 가능성이 높음을 시사한다. 본 연구결과를 근거로 청소년기의 음주가 성인기의 대사증후군으로 발전 되는 것을 예방하기 위해 지속적인 음주예방교육과 음주와 성인기 대사증후군 예측요인 간의 보다 엄밀한 연구를 제언한다.

• 한국융합학회논문지
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• 제8권12호
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• pp.417-423
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• 2017

본 연구의 목적은 대학생들을 대상으로 보완대체의학에 대한 인식 및 적용요인, 적용실태, 성별에 따른 만족도, 유용성에 관한 연구로 추후 보완대체의학의 활용방안을 마련하고자 시도되었다. 본 연구는 충남에 소재한 H대학교 대학생들을 대상으로 한 서술적 조사 연구이다. 본 연구 결과 인식, 적용요인 및 실태로는 보완대체의학을 현대의학의 보조 수단으로 인식한 응답이 150명(50.3%), 적용요인으로 정신적 심리적 안정감이 61명(20.3%), 적용질환으로는 근골격계 질환자가 101명(33.7%)으로 가장 높게 나타났으며, 성별에 따른 보완대체의학에 대한 만족도에서는 여성이 남성보다 높게 나타났다. 보완대체의학의 유용성 적용 시 장점은 2.60이었으며, 개선점과 특징은 2.32, 일반적 인식은 2.80을 보여 유용성에 대한 지식수준이 낮은 것으로 나타났다. 본 연구결과 사회의 기반이 되는 대학생들의 질병예방과 건강유지를 위하여 보완대체의학의 올바른 인식 보급이 필요하다. 또한 보완대체의학의 인식과 적용요인, 성별에 따른 만족도를 분석한 결과 향후 보완대체의학 프로그램 개발을 위한 정보로 제시할 수 있을 것이다.

• 한국미생물·생명공학회지
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• 제43권3호
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• pp.259-266
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• 2015

온난화, 고령화, 세계화로 인하여 변화하는 국내 보건환경에 현행 수질기준이 적합할 지 평가가 필요하다. 본 연구는 총대장균군 만으로 규정된 현행 온천수 수질기준의 타당성을 환경유래 내열성세균인 레지오넬라균 오염도를 검출로 평가하였다. 온천수에서 레지오넬라균을 검출한 7개의 논문에 보고된 미생물 자료에 대한 메타분석을 실시하였다. 레지오넬라균의 검출 유무의 오즈비는 총대장균군과 유의한 상관도를 보였다[odds ratio (OR), 3.1 (1.5−6.4, 95% CI), p = 0.002]. 그러나, 레지오넬라균 오염을 분변성 중온균인 총대장균군 지표가 감지할 수 있다는 점은 단순히 설명되지 않기에, 그 기작을 검토하였다. 레지오넬라균의 검출 유무는 일반세균수와 더 높은 오즈비를 보였고[4.0(2.2−7.2), p < 0.001], 40°C 미만의 수온범위에서 수온과 강한 상관도[OR, 4.3(1.4−13.6), p = 0.011], 50°C 이상에서는 수온과 음의 상관도를 보였다[OR, 0.2 (0.1−0.4), p < 0.001]. 따라서, 수온에 의하여 세균의 현존량이 결정되는 현상 때문에 총대장균군수와 레지오넬라균 유무가 연관성을 가진 것으로 판단된다. 이에 따르면, 총대장균군보다 일반세균수가 더 직접적으로 비분변성 병원체의 증감을 반응할 것으로 생각되므로, 일반세균수를 단일 수질관리 기준으로 사용하거나, 현행 기준에 일반세균수를 추가하는 것이 타당한 것으로 판단된다.

• 한국융합학회논문지
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• 제7권1호
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• pp.125-136
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• 2016

본 연구는 병원에서 근무하는 간호사의 환자안전문화인식과 환자안전간호활동의 융합적 관련성을 파악하여 병원에서의 환자안전사고 예방 및 환자안전관리활동을 위한 간호중재전략의 기초자료를 제공하고자 실시하였다. 연구방법은 B광역시 모병원에 근무하고 연구 참여에 동의한 간호사를 대상으로 2015년 2월 16일부터 2월28일까지 설문조사한 자료 266부를 SPSS 20.0 프로그램을 이용하여 분석하였다. 그 결과 대상자의 환자안전문화에 대한 인식 평균점수는 5점 만점에 3.60점이었고, 환자안전간호활동 평균점수는 5점 만점에 4.28점이었으며, 환자안전문화 인식의 하부영역인 사고보고빈도와 환자안전도 수준이 환자안전간호활동에 양(+)의 영향을 미치는 것으로 나타났다. 따라서 병원조직 내 원활한 의사소통과 긍정적인 보고체계구축을 통하여 환자안전문화에 대한 인식을 향상시킬 수 있도록 노력해야 할 것이다. 나아가 환자안전 교육과정 프로그램을 개발하여 병원 내 모든 직종을 포함한 간호사들에게 지속적으로 제공한다면 양질의 환자안전관리수행능력으로 질 높은 의료서비스가 제공될 것으로 기대된다.

• Journal of Preventive Medicine and Public Health
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• 제36권4호
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• pp.390-398
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• 2003

Objectives : To evaluate the degree of adolescent internet addiction, and investigate its relationship to the general characteristics, internet environments, and contents, especially the stress measured by the psychosocial wellbeing index-short form(PWI-SF). Methods : The data was obtained from self-administered questionnaires from 886 11th grade urban area students. The questionnaires consisted of general characteristics, internet user's environments, frequencies by internet contents, internet addiction test and PWI-SF. Results : The possible rate of internet use at home was 95.1%, and the area of most internet use was the home. The frequencies of internet game and porno site use were higher in males, with web searching and community uses higher in females. The total mean of internet addiction score was 56.8, and was higher for male than for female students. From multiple regression, as analyzed by the internet addiction score as a dependent variable, on-line friends, internet use times, years of internet use, frequencies of internet game, & porno site use, and PWI-SF scores were significant in male. Internet use times, the frequencies of internet game, chatting, community use, and PWI-SF score were significant in female. Four PWI-SF subscales(social role & self reliability, depression, general health & vitality, and sleep disturbance & anxiety) and internet addiction were significantly correlated in both male and female students, with depression having the most correlation. Conclusion : The results of this study suggest that intervention should be provided to prevent internal addiction, especially for coping with stress in Korean teenage students.

• 한국보건간호학회지
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• 제15권2호
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• pp.398-411
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• 2001

The separation system of pharmacy and clinic has begun on the purpose of preventing drug misuse and abuse since July 1st of 2000. The system revealed some conflicts between doctors. pharmacists and consumers. Consequently pharmaceutical law and related policies undergone some change. Now in an early period of the implementation of the system, the necessity to examine relevance of those policies and law enforcement to medical doctors' prescriptions pattern evolves. This study tries to verify the pattern through a field study. For the purpose, 930 prescriptions collected in May of 2001, from a pharmacy located in Gangnam-gu in Seoul, were analysed. The prescriptions were issued from several clinics: 459 prescriptions from otorhinolaryngological clinic(ENT), 177 from internal medicine clinic(IM), 130 from ophthalmic clinic(Opt), 52 from obstetric and gynecologic clinic(OB & GY), and 112 from miscellaneous clinics. ENT, IM, Opt. OB & GY are situated in a clinic building of 40m distance. The general findings are following: 1) $88.8\%$ of the total patients came from 5clinics in nearby single clinic building. 2) Average prescribing days were 6.2 days and the average number of used drugs were 4.0 drugs, i.e. 2-4 times of WHO criteria 1-2 drugs. 3) Use of antibiotics in the oral administration drugs rated $71.8\%(WHO: \;22.7\%)$ 4) Use of injection rated $31.3\%(WHO:\;17.2\%)$ 5) $96.2\%$ of the patients use multiple antibiotics in the injection and oral administration together. 6) The patients had multiple disease : ENT patients 1.7 disease and 1M patients has 2.7 disease in average and several regular prescribing types evolved particularly in the ENT prescription. With this result we found that drugs. especially antibiotics are still abused a lot, and there were significant differences in the number of used drugs and prescrbing days between the clinics. It implies somes differences of the preparation work and time for pharmacists. And preparation can be done in advance by pharmacists' own efforts through noticing regular prescribing types. The study suggests the followings: 1) Patient counseling should be done to minimize the incidence of adverse events. 2) The enforcement of the standardized differential preparation price system should be reconsidered. 3) Preparation of typical regularly appeared prescription in advance. which is regarded as 'a prearranged work between doctors and pharmacists' and has been prohibited should be reconsidered. 4) Drug utilization review program should be established to prevent drugs abuse. especially antibiotics abuse.

• 대한지역사회영양학회지
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• 제12권4호
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• pp.440-448
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• 2007

The objective of this study is to determine the effectiveness of 16-month milk consumption as a part of the health promotion community program for women in Asan. Subjects included 313 women belonging to the milk group (mean age = 69.1, range $47{\sim}89 y$) and 66 women to the control (mean age=43.6, range $20{\sim}69 y$) group. For those in the milk group, one cup (200 ml) of partially lactose-digested low-fat milk was provided everyday for 16 months. Each subject was interviewed to assess calcium intake by a 24-h recall after fasting blood was obtained for analyzing bone turnover markers, and calcaneus broadband ultrasound attenuation (BUA) was measured by quantitative ultrasound (QUS) on the left heel before and after the milk supplementation. After 16 months, the calcium intake levels changed from 55% of recommended dietary allowance (RDA) to 85% RDA in the milk group and from 73% RDA to 84% RDA in the control group. BUA were reduced from $67.9{\pm}8.1$ to $64.7{\pm}17.5$ dB/MHz for milk and from $90.4{\pm}13.0$ to $87.2{\pm}15.2$ dB/MHz for control groups. Paired t-test showed the changes of BUA for both groups (-3.24 and -3.15 dB/MHz for milk and control groups, respectively) were significant, but the two groups did not show any differences in absolute changes. When post-BUA was analyzed after age, initial BUA and menopausal status were controlled as covariates in ANCOVA model, the milk group showed significantly (p < 0.05) smaller changes than the control group (-3.50 vs -6.71 dB/MHz, respectively). According to a multiple regression analysis, milk consumption and initial BUA showed significant interaction meaning that those with lower initial BUA showed higher milk effects. We conclude that one-cup a day milk consumption for 16 month can prevent further bone loss and significantly improve calcium intake.