• Title/Summary/Keyword: Pretreatment effect

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Beneficial Effect of Scutellaria Balicalensis Georgi. Extract(SBGE) on Cisplatin-Induced Acute Renal Failure in Rabbits (황금약침액(黃芩藥鍼液)이 Cisplatin에 의해 유발된 급성신불전(急性腎不全)에 미치는 영향)

  • Ahn, Chang-Beohm;Kwon, Hae-Yon;Youn, Hyoun-Min;Jang, Kyung-Jeon;Song, Choon-Ho
    • Journal of Acupuncture Research
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    • v.19 no.3
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    • pp.156-167
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    • 2002
  • The present study was carried out to determine if Scutellaria balicalensis Georgi. extract (SBGE) exerts beneficial effect against the renal failure in rabbits. Rabbits were pretreated with SBGE orally for 7 days, followed by cisplatin injection (5 mg/kg, i.p.), cisplatin injection caused an increase in serum creatinine level, which was accompanied by a reduction in GFR. The fractional excretion of Na+, K+, glucose, and phosphate increased in cisplatin-treated animals, which was prevented by SBGE pretreatment. The uptake of p-aminohippurate, an organic anion, in renal cortical slices was inhibited by the administration of cisplatin, and the effect was prevented by SBGE. cisplatin injection increased lipid peroxidation, which was prevented by SBGE pretreatment. These results indicate that lipid peroxidation plays a critical role in cisplatin-induced acute renal failure. SBGE exerts the protective effect against acute renal failure induced by cisplatin, and its effect may be attributed to an antioxidant action.

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Effect of Gamma Irradiation on Wood Chip Saccharification Pretreated with NaOH (NaOH를 이용한 우드칩의 당화 전처리에 대한 감마선 조사 영향 연구)

  • Kim, Su-mi;Choi, Jong-il;Joe, Min-Ho;Kim, Jong-deog
    • Korean Chemical Engineering Research
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    • v.54 no.3
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    • pp.431-435
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    • 2016
  • The aim of this study was to investigate the effect of gamma irradiation on the pretreatment of wood chips with NaOH solution. The degree of saccharification was quantified by measuring reducing sugar and glucose concentrations after enzymatic hydrolysis. After pretreatment with 10 g/L NaOH, the wood chips were irradiated at the doses of 0, 50, 100, and 200 kGy, respectively. Among the irradiated samples, wood chips irradiated at the dose of 200 kGy had the highest reducing sugar concentration of 12.2 g/L. Also, to define the effect of irradiation before pretreatment, the wood chips were first gamma-irradiated and then pretreated with NaOH. When the NaOH treatment was conducted after irradiation at 200 kGy, the reducing sugar content was further increased to 13.4 g/L and glucose content of the wood chip was as high as 7.9 g/L. These results suggest that gamma irradiation may be the promising method for pretreatment of cellulose biomass.

Effect of Pretreatment on the Dissolution of Aluminum Alloy during Hydration Process (수화과정에서 전처리가 알루미늄 합금의 용출에 미치는 효과)

  • Lee, Byoung-Gu;Lee, Hoyeon;Tak, Yongsug
    • Corrosion Science and Technology
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    • v.12 no.5
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    • pp.215-219
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    • 2013
  • Aluminum alloy(3003) can be dissolved during hydration process with hot tap water. In order to increase the stability of aluminum alloy, it was pretreated with anodization and phosphoric acid before hydration process. The effect of pretreatment on the surface property changes was analyzed with X-ray Photoelectron Spectroscopy (XPS) and Inductively Coupled Plasma-Optical Emission Spectrometer (ICP-OES) and their results supported that the increase of hydroxyl group (-OH) on the surface formed during anodization and phosphorous acid treatment prevented the dissolution of aluminum alloy during hydration process at high temperature.

Callus Induction and Embryogenesis Through Pollen Culture in Paeonia albiflora PALL (작약의 화분배양에 의한 캘러스 및 배발생)

  • 김영숙;이병기
    • Korean Journal of Plant Tissue Culture
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    • v.22 no.1
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    • pp.13-17
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    • 1995
  • In order to induce haploid plant through pollen culture, pollens of Paeonia albiflora were cultured on MS liquid medium The development of micospore through pollen culture was examined The effect of low temperature (5$^{\circ}C$, 10 days) pretreatment on callus induction and embryogenesis in pollen culture was not evident Calli derived from pollen gave rise to globular embryos when transferred onto solid medium containing 0.5 mg/, 2,4-L. The effect of low temperature pretreatment and medium. combination to pollen viability was unrecognized. Pollen viability was reduced as the culture proceeded.

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Effect of Carbon Tetrachloride on the Changes of Guanase Activity in-Rats Fed Low or High Proteins Diet (食餌性 蛋白質含量에 따른 흰쥐에 사염화탄소 投與가 Guanase 活性變動에 미치는 영향)

  • Kang, Hoe-Yang
    • Journal of Environmental Health Sciences
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    • v.14 no.1
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    • pp.87-101
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    • 1988
  • The effect of hepatic injury produced by CCL, was studied on rats receiving a low protein-high carbohydrate (7% casein), standard protein (20% casein) and a high protein diet (30% casein). The rats fed low protein diet are resistant to CCl$_4$ in its effects on the liver as judged by histology, serum enzymes(guanase, ALT) and the content of hepatic protein. On the other hand, the pretreatment of hydrocortisone before injection of CCl$_4$ to the rats fed a standard diet, slightly decreased both serum ALT and guanase activities. In the pretreatment of actinomycin D, the liver and serum guanase activities were significantly decreased. It indicates that the cause of increasing serum guanase is based on the alteration of membrane permeability and the result of accelerated enzyme synthesis in liver cells of CCl$_4$ intoxicated rats.

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Effect of Renal Denervation and Glibenclamlde, ATP-dependent $K^+$ Channel Blocker, on Renal Action of SKP-450, $K^+$ Channel Opener, in Dog ($K^+$ Channel 개방제인 SKP-450의 신장작용에 대한 신장 신경제거와 ATP-의존성 $K^+$ Channel 차단제인 Glibenclamide의 영향)

  • 고석태;정지영
    • Biomolecules & Therapeutics
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    • v.8 no.1
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    • pp.53-63
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    • 2000
  • This study was performed to elucited the mechanisms of the antidiuretic action by SKP-450, a $K^+$ channel opener, given into the vein, and of the diuretic action observed only in the ipsilateral kidney, when given into a renal artery, in dog. The antidiuretic action of SKP-450 was not affected by renal denervation or pretreatment with glibenclamide, a ATP-dependent $K^+$ channel blocker. The diuretic action of SKP-450 was inhibited by renal denervation or pretreatment with glibenclamide. SKP-450 given into carotid artery had little effect on renal function. These results suggest that the antidiuretic action of SKP-450 given into the vein is caused by some endogenous substances probably not related to $K^+$ channel, whereas the diuretic action of SKP-450 observed only in ipsilateral kidney, when given into a renal artery, is provoked through $K^+$ channel related to renal nerves.

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Effect of Graft Copolymerization Conditions on Grafting Yield of AA and MA onto Polyester Fiber

  • Park, Myung-Ja
    • The International Journal of Costume Culture
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    • v.6 no.2
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    • pp.134-146
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    • 2003
  • Polyester of linear homopolymer poly(ethylene terephthalate)(PET) was chemically modified through the formation of branched copolymer to improve the undesirable properties of fiber. Photo-induced graft copolymerization of the acrylic monomers acrylic acid (AA) and methyl acrylate (MA) in the liquid and vapor phase, respectively, onto N,N-dimetylformamide (DMF)-pretreated PET fibers was carried out. The effect of various synthesis conditions and DMF pretreatment of the PET on the graft yield was investigated. Grafting mechanism was analysed. The grafting was promoted by increasing DMF pretreatment temperature and amount of DMF retention in the fiber. The increasing biacetyl and monomer flow time, and irradiation time enhanced the grafting up to a certain amount and thereafter it decreased.

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Mechanical Pretreatment of Municipal Waste Incineration Ash for Recovering Heavy Metals by the Horizontal Gyration Method

  • Park, Joonchul;Kaoru Masuda;Yamaguchi Hiroshi;Shigehisa Endoh
    • Proceedings of the IEEK Conference
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    • 2001.10a
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    • pp.664-667
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    • 2001
  • Segregation of binary particle systems in a horizontally gyrated bed has been experimentally studied to recover the heavy metals from municipal waste incineration (MWI) ash. Differences in density and size had less effect on segregation. Effective segregation took place under the centrifugal effect of 1 or less for any particle size ratio. Zn, Cu and Pb were concentrated in the upper side of bed by the horizontal vibration. However, there was less change in concentration for other metals such as Mg, Al and Fe etc. The separation system with the horizontal gyrating separator proved to be an effective method for the pretreatment of recovering Zn, Cu and Pb from incineration residues.

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Effect of Pretreatments on Graphene Coated Bipolar Plate of PEMFC on Electrochemical (전처리가 그래핀을 코팅한 고체고분자 연료전지 분리판의 전기화학적 특성에 미치는 영향)

  • Cha, Seong-Yun;Lee, Jae-Bong
    • Corrosion Science and Technology
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    • v.13 no.6
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    • pp.224-232
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    • 2014
  • Effect of pretreatments on the graphene coated bipolar plate of proton exchange membrane fuel cell(PEMFC) was investigated in simulated environments for PEMFC by using electrochemical measurement techniques. Interfacial contact resistance(ICR) between the graphene coated bipolar plate and the gas diffusion layer(GDL) was measured. The value of ICR decreased with an increase in compaction stress($20N/cm^2{\sim}220N/cm^2$). ICR of graphene coated bipolar plate was higher than that of bare 316L stainless steel. However, Potentiodynamic measurement results showed that the corrosion resistance of graphene coated bipolar plate was higher than that of bare 316L stainless steel. $H_2SO_4$ acid pretreatment was the most effective among various pretreatments. The lowest ICR and the corrosion current density were obtained when using $H_2SO_4$ solution pretreatment.

Protective Effect of Diallyl Disulfide on the Carbon Tetrachloride-Induced Hepatotoxicity in Mice (Diallyl Disulfide 가 사염화탄소에 의한 마우스 간손상에 미치는 영향)

  • 이상일;김승희;조수열
    • Journal of the East Asian Society of Dietary Life
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    • v.3 no.2
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    • pp.121-128
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    • 1993
  • This study was intended to clarify the protective mechanism of diallyl disulfide on the carbon tetrachloride-induced hepatotoxicity in mice. It was observed that a powerfully increment of serum alanine aminotransferase activity and hepatic lipid peroxide content after carbon tetrachloride injection were markedly inhibited by the pretreatment of diallyl disulfide (20mg/kg) for 5 days. It was also observed that hepatic aminopyrine demethylase and xanthine ocidase as free radical generating enzymes as well as superoxide dismutase and catalase activities as free frdical scavenging enzymes and hepatic glutathione content were not changed by the pretreatment with diallyl disulfide. But, treatment with diallyl disulfide did signifiantly increase cytosolic glutathione S-transferase activity. However, glutathione S-transferase activity in the presence of diallyl disulfide was not affected in vitro. Therefore, it is concluded that mechanism for the observed preventive effect ofdiallyl disulfide against the carbon tetrachloride-induced hepatotoxicity can be due to the engancement of glutathione S-transferase activity.

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