• Nuclear Engineering and Technology
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• 제55권6호
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• pp.2053-2068
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• 2023

Following a loss of coolant accident (LOCA), prestressing concrete containment vessels (PCCVs) may experience high thermal load as well as internal pressure. The high temperature stress would increase the risk of premature damage to the containment, which reduces the safety margin during the increasing internal pressure. However, current investigations cannot clearly address the issues of thermal-pressure coupling effect on damage propagation and thus safety of the containment. Thus, this paper offers three simple and powerful damage parameters to differentiate the severity of damage of the containment. Moreover, despite of the temperature action severely threatening the pressure performance of the containment, the research regarding the improvement of the resistant performance of the containment is quite scarce. Therefore, in this paper, a comprehensive comparison of damage propagation and mechanism between conventional and fiber-reinforced concrete (FRC) containments is performed. The effects of fiber characteristics parameters on damage propagation of structures following the LOCA are also specifically revealed. It is found that the proposed damage indices can properly indicate state of damage in the containment body and the addition of fiber can be used to obviously mitigate the damage propagation in PCCV considering the thermal-pressure coupling.

• 디지털융복합연구
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• 제14권4호
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• pp.487-494
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• 2016

본 연구는 고령여성의 12주간 건강운동프로그램을 통해 인슐린저항성 및 혈중지질의 변화를 살펴보고자 하였다. 이를 위해 운동집단(EG)과 통제집단(CG)으로 구분하여 두 그룹을 선정하였다. 운동집단에는 건강운동프로그램을 12주간 적용하였으며, CG는 통제집단으로서 프로그램에 참여하지 않고 비교집단으로 활용하였다. 운동집단에 적용된 건강운동프그램은 유산소운동과 밴드운동을 주 당 4회 준비운동과 정리운동을 포함해 60분간 실시되었다. 자료분석은 고령여성의 12주간 건강운동프로그램 적용 전과 후에 측정하여 프로그램의 효과를 검증하고자 하였다. 이와 같은 절차를 통해 다음과 같은 결론을 얻었다. 첫째, 고령여성의 12주간의 건강운동프로그램은 혈중지질과(TC, HDL, LDL, TG) 혈압(SBP, DBP) 변화에 유의한 상호작용효과를 나타냈다(p<.05). 둘째, 고령여성의 12주간의 건강운동프로그램은 인슐린저항성(insulin, glucose) 변화에 유의한 상호작용효과를 나타냈다(p<.05). 본 연구는 고령여성의 건강운동프로그램을 통해 인슐린저항성 및 혈중지질 변화에서 긍정적 개선을 나타냈다.

• 한국항공우주학회지
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• 제47권9호
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• pp.629-641
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• 2019

고온, 고압의 연소가스에 의해 유입되는 많은 열을 효과적으로 차단하여 고체 로켓 노즐의 공력형상을 최대한 유지하면서 구조물의 온도 상승을 일정수준 이하로 제한하기 위해 연소가스와 접하는 위치에 내삭마성이 우수한 C/C 복합재 등의 내열재를, 그 배면에는 열확산계수가 낮은 단열재를 적용한다. 내산화성이 우수한 SiC/SiC 복합재는 가스터빈 엔진에 적용되고 있으며, 경량화와 내열성 향상으로 인해 엔진 성능 증가에 기여하고 있다. 극초음속으로 비행하는 스크램제트는 흡입 공기 온도가 매우 높아서 흡열 연료를 냉각제로 사용하는 C/SiC 구조물 개발 연구가 수행되고 있다. 본 논문에서는 고체 로켓 노즐, 가스터빈 엔진 및 램제트/스크램제트 추진기관에 사용되는 다양한 내열 복합재의 특성, 적용사례 및 개발 동향을 고찰하였다.

• 한국해양공학회지
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• 제28권1호
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• pp.85-92
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• 2014

Offshore fields are increasingly important for the development of offshore resources due to the growing energy needs. However, an offshore field for oil and gas production has difficult development conditions, e.g., high temperature, high pressure, sweet/sour compositions of fluids, etc. Corrosion is one of the biggest issues for offshore pipeline engineering. In this study, a Corrosion Resistant Alloy (CRA) pipe for corrosion prevention was investigated through its global demand and trends, and three types of CRA pipelines were introduced with detailed explanations. The usefulness of CRA was also evaluated in comparison to a carbon steel pipeline in terms of the structural strength, cost, and other factors. Offshore pipeline engineering, including mechanical design and verification of the results through an installation analysis based on numerical software, was performed for the carbon steel type and solid CRA type. The results obtained from this study will be useful data for CRA pipeline designers and researchers.

• 생명과학회지
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• 제22권9호
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• pp.1268-1276
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• 2012

사람의 감염증 치료에 사용되는 carbapenem계 약제에 대한 내성균의 출현 및 확산은 감염증 치료를 제한할 뿐만 아니라 집단 발병의 원인이 될 수 있다. 이에 본 연구에서는 ${\beta}$-lactam 약제에 내성을 갖는 Pseudomonas aeruginosa (P. aeruginosa)를 대상으로 metallo-beta-lactamase (MBL)의 유전형을 규명함으로써 내성세균의 감염증 치료지침 및 확산방지책 마련에 기초 자료를 제공하고자 하였다. 본 연구의 대상이 된 254개의 임상 검체 중에서 42주의 P. aeruginosa 를 분리하여 imipenem 혹은 meropenem에 내성을 나타내는 Hodge 변법과 EDST에서 각각 28주와 23주가 양성반응을 보였다. DNA의 염기서열 분석결과 $bla_{IMP-6}$ 유전자 보유균이 8주, $bla_{VIM-2}$ 유전자 보유균이 17주로 59.5%(25/42)가 MBL을 생성하는 것으로 나타났다. $bla_{IMP-6}$의 유전자 환경은 $bla_{IMP-6}$-qac-aacA4-$bla_{OXA-1}$-aadA1 유전자 배열을 지니고 있었다. 또한 ERIC PCR 결과 IMP-6과 VIM-2를 생성하는 일부 균주에서 역학적 연관성이 있음이 확인되었다. 본 연구에서 분리한 carbapenem계 항균제 내성 P. aeruginosa가 보유한 $bla_{IMP-6}$ 유전자는 대구지역에서 발병이 보고된 유전자의 gene cassette와 일치하는 것으로 확인되었다. 따라서 이들 세균이 지역사회에 정착하고 있고 이들을 보유한 세균에 의한 감염증 치료시 치료약제에 대한 선택압을 증가시킬 것으로 우려된다. 그러므로 항균제 내성 검사를 통하여 적절한 항균제를 선택하고, 항균제 내성균들의 출현과 확산을 막는 연구가 계속되어야 할 것으로 생각된다.

• Journal of Pharmaceutical Investigation
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• 제35권3호
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• pp.173-177
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• 2005

Addition of 30% propylene glycol was required to maintain sink condition in the evaluation of percutaneous absorption of estradiol and norethindrone acetate. The permeability of estradiol was higher in silicone and SIS adhesives. However, estradiol was crystallized in silicone, SIS, and SBS adhesive matrix. The permeability ratio of estradiol or norethindrone acetate from acrylic pressure sensitive adhesives varied widely depending on the functional group of the acrylic adhesives. PEO grafting to acrylic adhesive seemed to change physicochemical property of acrylic adhesive and increased the permeability of estradiol and norethindrone acetate significantly. On the contrary, highly cross-linked enhancer compatible acrylic adhesive decreased the permeability of both estradiol and norethindrone acetate. $Span^{\circledR}$ 20 provided the highest enhancing effect on the permeability of both estradiol and norethindrone acetate followed by oleic acid and $Crovol^{\circledR}$ EP40. The permeability of the drugs from the developed system was comparable to that from commercial $Combitran^{\circledR}$, although significantly lower amount of estradiol and norethindrone acetate were loaded in the developed system.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2001년도 봄 학술발표회 논문집
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• pp.259-266
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• 2001

This paper presents the results of a structural analysis to determine design variables such as the inner basket array type, and thicknesses of the outer shell and the lid and bottom of a spent nuclear fuel disposal canister. The canister construction type introduced here is a solid structure with a cast iron insert and a corrosion resistant overpack, which is designed for the spent nuclear fuel disposal in a deep repository in the crystalline bedrock, entailing an evenly distributed load of hydrostatic pressure from the groundwater and large swelling pressure from the bentonite buffer. Hence, the canister must be designed to withstand these large pressure loads. Many design variables may affect the structural strength of the canister. In this study, among those variables, the array type of inner baskets and thicknesses of outer shell and lid and bottom are attempted to be determined through a linear static structural analysis. Canister types studied here are one for the pressurized water reactor (PWR) fuel and another for the Canadian deuterium and uranium reactor (CANDU) fuel.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2005년도 춘계 학술발표회 논문집
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• pp.870-877
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• 2005

This study examined a case of collapse and reinforcement of the colluvial deposit slope in Kyeongnam Geoje Area. The reason for the collapse was found first in the reduction of the resistant force due to slope-cut for constructing retaining walls. This decreased the resistant force against sliding, which enabled precipitation during the rainy period to seep into the ground in the upper colluvium, resulting in increase in porewater pressure. This leads to decreased shear strength and increased sliding force, which ultimately caused the collapse of the slope. For the long-term stability, methods attained for stability reinforcement are summarized in the following table.

• Structural Engineering and Mechanics
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• 제39권2호
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• pp.287-301
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• 2011

This paper is focused on the residual capacity of steel columns, as a damage criterion. Load-Impulse (P-I) diagrams are frequently used for analysis, design, or assessment of blast resistant structures. The residual load carrying capacity of a simply supported steel column was derived as a damage criterion based on a SDOF computational approach. Dimensionless P-I diagrams were generated numerically with this quantitative damage criterion. These numerical P-I diagrams were used to show that traditional constant ductility ratios adopted as damage criteria are not appropriate for either the design or damage assessment of blast resistant steel columns, and that the current approach could be a much more appropriate alternative.

• Wind and Structures
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• 제26권6호
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• pp.369-382
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• 2018

Tornadoes are vertical swirling air formed because of the existence of layers of air with contrasting features of temperature, wind flow, moisture, and density. Tornadoes induce completely different wind forces than a straight-line (SL) wind. A suitably designed building for an SL wind may fail when exposed to a tornado-wind of the same wind speed. It is necessary to design buildings that are more resistant to tornadoes. In tornado-damaged areas, dome buildings seem to have less damage. As a dome structure is naturally wind resistant, domes have been used in back yards, as single family homes, as in-law quarters, man caves, game rooms, storm shelters, etc. However, little attention has been paid to the tornadic wind interactions with dome buildings. In this work, the tornado forces on a dome are computed using Computational Fluid Dynamics (CFD) for tornadic and SL wind. Then, the interaction of a tornado with a dome and a prism building are compared and analyzed. This work describes the results of the tornado wind effect on dome and prism buildings. The conclusions drawn from this study are illustrated in visualizations. The tornado force coefficients on a dome building are larger than SL wind forces, about 120% more in x- and y-directions and 280% more in z-direction. The tornado maximum pressure coefficients are also higher than SL wind by 150%. The tornado force coefficients on the prism are larger than the forces on the dome, about 100% more in x- and y-directions, and about 180% more in z-direction. The tornado maximum pressure coefficients on prism also are greater those on dome by 150% more. Hence, a dome building has less tornadic load than a prism because of its aerodynamic shape.