• Asian-Australasian Journal of Animal Sciences
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• v.28 no.6
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• pp.876-887
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• 2015

Dicer, an ribonuclease type III type endonuclease, is the key enzyme involved in biogenesis of microRNAs (miRNAs) and small interfering RNAs (siRNAs), and thus plays a critical role in RNA interference through post transcriptional regulation of gene expression. This enzyme has not been well studied in the Indian water buffalo, an important species known for disease resistance and high milk production. In this study, the primary coding sequence (5,778 bp) of bubaline dicer (GenBank: AB969677.1) was determined and the bubaline Dicer1 biocomputationally characterized to determine the phylogenetic signature among higher eukaryotes. The evolutionary tree revealed that all the transcript variants of Dicer1 belonging to a specific species were within the same node and the sequences belonging to primates, rodents and lagomorphs, avians and reptiles formed independent clusters. The bubaline dicer1 is closely related to that of cattle and other ruminants and significantly divergent from dicer of lower species such as tapeworm, sea urchin and fruit fly. Evolutionary divergence analysis conducted using MEGA6 software indicated that dicer has undergone purifying selection over the time. Seventeen divergent sequences, representing each of the families/taxa were selected to study the specific regions of positive vis-$\grave{a}$-vis negative selection using different models like single likelihood ancestor counting, fixed effects likelihood, and random effects likelihood of Datamonkey server. Comparative analysis of the domain structure revealed that Dicer1 is conserved across mammalian species while variation both in terms of length of Dicer enzyme and presence or absence of domain is evident in the lower organisms.

• Transactions of the Korean Society of Automotive Engineers
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• v.16 no.3
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• pp.38-43
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• 2008

The hydroforming technology has been spreaded dramatically in automotive industry last 10 years. Itmay cause many advantages to automotive applications in terms of better structural integrity of the parts, lower cost from fewer part count, material saving, weight reduction, lower springback, improved strength and durability and design flexibility. In this study, the whole process of rear sub-frame parts development by tube hydroforming using steel material having tensile strength of 440MPa grade is presented. At the part design stage, it requires feasibility study and process design aided by CAE (Computer Aided Design) to confirm hydroformability in details. Effects of parameters such as internal pressure, axial feeding and geometry shape in automotive rear sub-frame by hydroforming process were carefully investigated. Overall possibility of hydroformable sub-frame parts could be examined by cross sectional analyses. Moreover, it is essential to ensure the formability of tube material on every forming step such as pre-bending, preforming and hydroforming. In addition, all the components of prototyping tool are designed and interference with press is examined from the point of geometry and thinning.

• Asian Journal of Atmospheric Environment
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• v.11 no.1
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• pp.1-14
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• 2017

For the quantitative analysis of volatile organic compounds (VOC), the use of a proper solvent is crucial to reduce the chance of biased results or effect of interference either in direct analysis by a gas chromatograph (GC) or with thermal desorption analysis due to matrix effects, e.g., the existence of a broad solvent peak tailing that overlaps early eluters. In this work, the relative performance of different solvents has been evaluated using standards containing 19 VOCs in three different solvents (methanol, pentane, and hexane). Comparison of the response factor of the detected VOCs confirms their means for methanol and hexane higher than that of pentane by 84% and 27%, respectively. In light of the solvent vapor pressure at the initial GC column temperature ($35^{\circ}C$), the enhanced sensitivity in methanol suggests the potential role of solvent vapor expansion in the hot injector (split ON) which leads to solvent trapping on the column. In contrast, if the recurrent relationships between homologues were evaluated using an effective carbon number (ECN) additivity approach, the comparability assessed in terms of percent difference improved on the order of methanol (26.5%), hexane (6.73%), and pentane (5.24%). As such, the relative performance of GC can be affected considerably in the direct injection-based analysis of VOC due to the selection of solvent.

• Journal of Digital Contents Society
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• v.16 no.3
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• pp.355-363
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• 2015

In this paper, we propose a system for controlling the seat of the electric wheelchair depending on the slope of the terrain in real time by using the ATmega smart control based on the board. Smart control board includes a gyro sensor, an acceleration sensor and Tilt sensor, when the electric wheelchairs pass slope of the terrain, they use three sensors to identify terrain configuration in real time. We also applied the Complementary Filter in the gyro sensor and acceleration sensor, so the electric wheelchairs know the exact terrain by solving the interference during the movement. Based on this, the noise power wheelchair due to the movement will be reduced, the seat continues reliably movement without being vibration. In this paper, providing an application on the smart phone platform for the convenience of users who are not familiar with how to use electric wheelchairs, they can easily control wheelchairs. Control platform of the smart phone is able to monitor the electric wheelchair in real-time, with regard to pressure prevention, help the slope of the seat to be arbitrarily controlled.

• Transactions of the Korean Society of Mechanical Engineers
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• v.14 no.5
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• pp.1311-1319
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• 1990

For the purpose of preventing the flow undulation in the cascade of steam turbine, the blades are made into a constant expansion rate in static pressure. And the flow in those cascades is transonic or supersonic in the range of 0.7-2.0 in Mach number. As a consequence, an oblique shock wave, known as inner or outer edge shock wave, arises in the flow of cascades. Especially when the steam in cascades is in a state of high wetness, nonequilibrium condensation and condensation shock wave occur, and they give rise to an interference with oblique shock wave. In the present study the case of expansion of moist air through a supersonic nozzle of constant expansion rate, which behaves similar to that of wet steam, was adopted. The effect of nonequilibrium condensation on the oblique shock wave generated by placing the wedge into the supersonic part of the nozzle was investigated. Furthermore, the relationship between nonequilibrium condensation zone and incident point of the oblique shock wave, oblique shock wave angle, the variations of angles of incident and reflected shock waves due to the variation of initial stagnation supersaturation and the relationship between the height of Mach stem and initial stagnation supersaturation are discussed.

• Proceedings of KOSOMES biannual meeting
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• 2007.05a
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• pp.169-174
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• 2007

The purpose in having a control rod an a buoy system is to control the motion of it. The system may be composed entirely af a single circular cylinder finder and a lang mooring anchor cable. A control rod has one function to perform in meeting its purpose, and that is to develop a control force in consequence of its orientation and movement relative to the water. The forces and moments generated as a result of the effects of mutual interference, then determine the stability characteristics of the body. In this paper, the study of control-rod-attached buoy's 2-dimensional section was accomplished. model tests and numerical simulations had been carried out with different diameters of control rods. and varying the Reynolds number $Re=5,000{\sim}25,000$ based an the cylinder diameter(D=50mm) to. predict the performance af the body and the 2 frame particle tracking method had been used to obtain the velocity distribution in the flaw field 50mm circular cylinder had been used during the whale experiments and measured results had been compared with each other.

• The Journal of Korean Obstetrics and Gynecology
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• v.27 no.1
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• pp.140-151
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• 2014

Objectives: Cold hypersensitivity has been regarded to be associated with digestive function. This study is aims to evaluate the correlation between digestive function and coldness of hands. Methods: We made a research of 80 women who is in ${\bigcirc}{\bigcirc}$ University. The patients were subjected to thermometer, and those with thermal difference between upper arm and palm were diagnosed with cold hypersensitivity. The patients were divided into two group by cold hypersensitivity group (n=20), and non-cold hypersensitivity group (n=19), and 39 women are mesured by Nepean dyspepsia index-Korean version (NDI-K) to evaluate the severity of functional dyspepsia. Results: There was no difference between two groups on age, height, weight. In functional dyspepsia symptom score, 6 symptoms (Pain in upper abdomen, Burning in upper abdomen, Cramps in upper abdomen, Pressure in upper abdomen, Vomiting, Bad breath) out of 15 were significantly increased in cold hypersensitivity group compared with non-cold hypersensitivity group. And in quality of life score, 3 domains (Tension/sleep, Interference with daily activities, Knowledge/control) out of 5, and total quality of life score were significantly decreased in cold hypersensitivity group compared with non-cold hypersensitivity group. Conclusions: This study shows the correlation between cold hypersensitivity and digestive function.

• PNF and Movement
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• v.17 no.2
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• pp.215-222
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• 2019

Purpose: The objective of this study was to investigate whether augmented low-dye taping treatment, which consists of low-dye, reverse-six, and calcaneal-sling taping, is effective in alleviating the collapse of the medial longitudinal arch, which is used for physical balancing during one leg standing. Methods: The subjects comprised 27 students in their 20s whose navicular bone height was lowered by 10 mm or more when evaluated using the navicular drop test. Those with interference factors like deformities, fractures, or traumas were excluded. Frequency-division multiplexing was used to measure one leg standing, and the method to avoir the average each time after 3 times of measurement was applied. Results: Significant differences in the center of pressure (COP) path length, COP average velocity, and forefoot force were observed during left leg standing (p<0.05), but for right leg standing, only changes in forefoot force were noted. Conclusion: Based on the changes to the non-dominant leg in terms of COP path length, COP average velocity, and forefoot force, the immediate effect of augmented low-dye taping, which combines three types of anti-pronation taping, on one leg standing balance in people with flat feet was confirmed.

• Journal of Dental Anesthesia and Pain Medicine
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• v.21 no.2
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• pp.155-165
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• 2021

Background: This study aimed to assess the course of anxiety and pain during lower third molar (LTMo) surgery and explore the role of mobile and single-channel electroencephalography under clinical and surgical conditions. Methods: The State-Trait Anxiety Inventory (STAI), Corah's Dental Anxiety Scale (DAS), and Interval Scale of Anxiety Response (ISAR) were used. The patient self-rated anxiety (PSA), the pain felt during and after surgery, EEG, heart rate (HR), and blood pressure (BP) were assessed. Results: The Attention (ATT) and Meditation (MED) algorithms and indicators evaluated in this study showed several associations. ATT showed interactions and an association with STAI-S, pain during surgery, PSA level, HR, and surgical duration. MED showed an interaction and association with DAS, STAI-S, and pain due to anesthesia. Preclinical anxiety parameters may influence clinical perceptions and biological parameters during LTMo surgeries. High STAI-Trait and PSA scores were associated with postoperative pain, whereas high STAI-State scores were associated with more pain during anesthesia and surgery, as well as DAS, which was also associated with patient interference during surgery due to anxiety. Conclusions: The findings suggest that single-channel EEG is promising for evaluating brain responses associated with systemic reactions related to anxiety, surgical stress, and pain during oral surgery.

• The Journal of the Acoustical Society of Korea
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• v.42 no.6
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• pp.584-593
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• 2023

This study attempted to develop repetitive impact sources similar to real-life floor impact noise and to find an assessment approach corresponding to this new impact source. The necessity for the development of the new impact source arises from the fact that issues related to floor impact noise in actual residential buildings mainly stem from children running. However, the standard impact sources which have been used for measuring and evaluating floor impact noise are of single-impulse type, which differs from the actual problematic impact sources. The study encompassed 18 evaluation items, and the results suggest that items applicable for assessing floor impact noise include psychological effects (annoying, becoming angry), disturbances to daily life (interference with sleep, disruption of relaxation), and physiological effects (elevated blood pressure). These items can be employed individually and, depending on the type of evaluation for floor impact noise, can be selectively utilized. By doing so, more comprehensive evaluations of auditory experiments in laboratories or assessments of residential noise in living environments related to floor impact noise could be conducted.