• Transactions of the Korean Society of Mechanical Engineers B
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• v.29 no.11 s.242
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• pp.1265-1276
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• 2005

The elliptic conceptual second moment models for turbulent heat fluxes, which are proposed on the basis of elliptic-blending and elliptic-relaxation equations, are applied to calculate the combined forced and natural turbulent convection in a vertical plane channel. The models satisfy the near-wall balance between viscous diffusion, viscous dissipation and temperature-pressure gradient correlation, and also have the characteristics of approaching its respective conventional high Reynolds number model far away from the wall. Also the models are closely linked to the elliptic blending model which is used for the prediction of Reynolds stress. In order to calibrate the heat flux models, firstly, the distributions of mean temperature and scala flux in fully developed channel flow with constant wall difference temperature are solved by the present models. The buoyancy effect on the turbulent characteristics including the mean velocity and temperature, the Reynolds stress tensor, and the turbulent heat flux vector are examined. In the opposing flow, the turbulent transport is greatly enhanced with both the Reynolds stresses and the turbulent heat fluxes being remarkably increased; whereas, in the aiding flow, the opposite change is observed. The results of prediction are directly compared to the DNS to assess the performance of the model predictions and show that the behaviors of the turbulent heat transfer in the whole flow region are well captured by the present models.

• Journal of Chest Surgery
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• v.33 no.4
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• pp.285-289
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• 2000

Background: For AVR using conventional prosthetic valves in adult patients with a narrow aortic root, aortic root enlargement is necessary to reduce postoperative pressure gradient across the aortic valve (ΔP). An evaluation of early and mid-term results of aortic root enlargement with AVR and echocardiographic follow up of ΔP and left ventricular function was performed. Method: From Aug. 1991 to Feb. 1998, eighteen patients aged 17 to 59 years(mean, 38$\pm$12 years) underwent Manouguian procedure with AVR. Aortic annular circumstance was enlarged 10.0mm to 18.0mm(mean, 12.6$\pm$6.3mm). Eight patients(44.0%) had NYHA class III status before operation, and seven cases of them underwent concomitant MVR. Valve pathology was ASr in 6 cases, AS in 4 cases, nd ASr+MSr in 8 cases. Replaced valve size was 21mm in 8 cases and 23 mm in 10 cases, and St. Jude Medical mechanical valve was used in 10 cases and Carbomedics in 8 cases. Result: Follow-up duration was 6 to 57 months (mean, 26$\pm$18 months), and total follow-up was 287 patient-year. There were one hospital death and one late death, therefore, actuarial survival rate was 85.7% at 56 months. Peak ΔP wad decreased significantly at postoperative mid-term period as 13$\pm$5mmHg, compared with thepreoperative one (42$\pm$8mmHg) (p<0.01). LVM(gm/$m^2$) was also diminished as 35.8%(115$\pm$36gm/$m^2$)at postoperative mid-term period, compared with preoperative one (179$\pm$56gm/$m^2$)(p<0.05). Conclusion: There were no specific complications related to the procedure. And we could have adequate enlargement of aortic annulus to suitable prosthetic valve that have no effect of patient-prosthese mismatch.

• Journal of Embryo Transfer
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• v.15 no.1
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• pp.1-8
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• 2000

The ultrasound-guided oocytes cllection (ovum pick-up ; OPU) has become a substitution for superovlation in cattle. The objective of this study was to examine the effect of OPU frequency on the in vitro production of embryos in Hanwoo cattle. Six cycling Hanwoo cows were distributed into two groups for either once or twice weekly OPU sessions. Oocytes were collected by ultrasound-guided follicle aspiration(SA600) using a 6.5HMz transducer and attached with 18 gauge needle, with vacuum pressure of 40 mmHg. The cumulus-oocyte complexes (COCs) collected from each donor were matured in TCM 199 supplemented with 10% fetal bovine serum at 5% CO2 in air at 38.5$^{\circ}C$ for 22h and in vitro matured oocytes were co-incubated with sperm(separated by Percoll gradient) for 6h. The zygotes were co-cultured on cumulus cell monolayer in 10ul droplets in the same culture medium and conditions used for IVM for 7 days. On Day 7 of culture, development to blastocysts was examined. Although the number of oocytes collected was variable depending on individuals, overall embryo production in the twice per week OPU sessions was better that in the once per week sessions(6~21 vs 2~7 blastocysts produced, respectively). Two cows(E, A) were good oocyte donors and embryo production was superior in cow C ; however, cow F was a poor donor as compared to the others. In conclusion, these results suggest that for embryo production, twice weekly OPU sessions were better than once per week for producing embryos in vitro from Hanwoo cattle.

• Journal of the Society of Naval Architects of Korea
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• v.34 no.4
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• pp.42-52
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• 1997

The basic principle of underwater ram-jet as a unique marine propulsion concept showing vary high cruise speed range(e. g. 80-100 knots) is the thrust production by the transfer of the potential energy of compressed gas to the operating liquid through kinetic mixing process. This paper is aimed to investigate the propulsive efficiency of the nozzle flow in underwater ram-jet at the speed of 80 knots for the buried type vessel. The basic assumption of the theoretical analysis is that mixture of water and air can be treated as incompressible gas. For an optimized nozzle configuration obtained from the performance analysis, preliminary data for performance evaluation are obtained and effects of nozzle inner wall friction, ambient temperature, ambient pressure, water density, gas velocity, bubble radius, flow velocity, diffuser area ratio, mass flow ratio and water velocity gradient are investigated.

• 한국해양학회지
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• v.21 no.4
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• pp.203-210
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• 1986

A linear parallel transport model is formulated and applied to an idealized Yellow Sea, With this simple analytical model, the hither-to suspected upwind flow phenomena in the southern Yellow Sea can be reasonably explained. In deep waters where the local depth exceeds a critical depth (Hc=53m in the present model sea), pressure gradient force dominates over wind stress and contributes to an upwind flow. The estimated upwind flow velocity increases with wind speed and a maximum upwind flow occurs along the axis of the Yellow Sea embayment. For the typical south wind of 5-10 knots in summer, the upwind (southward) flow velocity along the axis of the Yellow Sea is estimated to be 1-5cm s$\^$-1/. While, for the typical north wind of 10-15 knots in winter, the upwind (northward) flow velocity is 5-12cm s$\^$-1/. These velocity ranges can be served as rough estimates for the intrusion velocity of the Yellow Sea Bottom Cold Water in summer and the Yellow Sea Warm Current in winter, respectively.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.39 no.5
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• pp.433-441
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• 2011

The optimization of a centrifugal compressor was conducted. The ANN (Artificial Neural Network) was adopted as an optimization algorithm, and it was learned and trained with the DOE (Design of Experiment). In the DOE, it was predicted the main effect and the interaction effect of design variables to the objective function. The ANN was improved in the optimization process using the GA (Genetic Algorithm). When any output at each generation was reached a standard level, it was re-calculated by the CFD (Computational Fluid Dynamics) and it was applied to develop a new ANN. After 6th generation, the prediction difference between ANN and CFD was less than 1%. A pareto of the efficiency versus the pressure ratio was obtained through the 21th generation. Using this method, the computational time for the optimization was equivalent to the time consumed by the gradient method, and the optimized results of multi-objective function were obtained.

• Economic and Environmental Geology
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• v.22 no.3
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• pp.237-252
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• 1989

The Inseong gold-silver mine is located 3Km northwest of Suanbo, Choongcheongbugdo, Republic of Korea. The mine occurs in the shear zone formed by tension fractures within the Hwanggangri Formation of the Ogcheon metamorphic belt. Ore minerals found in the gold-silver bearing hydrothermal quartz vein composed mainly of pyrite, arsenopyrite, sphalerite, galena and minor amount of chalcopyrite, pyrrhotite, stannite, bismuthininte, native bismuth, chalcocite, electrum and tellurian canfieldite(?). The gangue minerals are quartz, calcite, chlorite and rhodochrocite. Wallrock alterations such as chloritization, silicitication, pyritization, carbonitization and sericitization can be observed in or around the quartz vein. According to the paragenetic sequence, quartz vein structure and mineral assemnlages, three different stages of ore formation can be recognized. The physico-chemical environment of ore formation in this deposit shows slight variation from stage to stage, but the condition of main ore deposition can be summarized as follows. Fluid inclusion, S-istope geothermometry and geothermometry based on mineral chemistry by use of arsenopyrite and chlorite show the ore was formed at temperature between 399 and $210^{\circ}C$ from fluids with salinities of 3.3-5.8 wt.% equivalent NaCl. It indicates that pressure during the mineralization is less than 0.6 Kb corresponding to a depth not greater than 1Km. S-isotope data suggests that thermal fluid may have magmatic origin wit some degree of mixing with meteoric water. In coclusion, the Inseong gold-silver deposit was formed at shallow depth and relatively high-temperature possibly with steep geothermal gradient under xenothermal condition.

• Microbiology and Biotechnology Letters
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• v.31 no.1
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• pp.51-56
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• 2003

The angiotensin I converting enzyme (ACE) has an important role in the maintenance of blood pressure. The ACE inhibitory activities of foods have recently been studied. We tried to isolate ACE inhibitory peptides from the Flavourzyme (FZ), Pescalase (PE), and Thermolysine (TH) protease digests of corn gluten, which was restricted to the use the source of food for digestion problem. The FZ, PE, TH/PE protease hydrolyzed corn gluten and the inhibitory activities of the hydrolyzates for ACE were measured. Major fractions were isolated from the digests using ODS chromatography after treating with ethanol in step gradient. The ACE inhibitors were further purified by Bio-Gel P-2 column and reverse phase HPLC. Five inhibitory peptides were isolated. Their amino acids were sequenced as LPF ($IC_{50}$ = 40$\mu$M), GPP ($IC_{50}$ = 17.6$\mu$M), PNPY ($IC_{50}$ = 30.7$\mu$M), SPPPFYL ($IC_{50}$ = 63 $\mu$M), and SQPP ($IC_{50}$ = 17.2$\mu$M).

• Atmosphere
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• v.28 no.2
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• pp.187-200
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• 2018

The heavy snowfall phenomenon with thunder and lightning occurred in Yeongdong coastal region on 20 January 2017. Amount of snow on that day was a maximum of 47 cm and was concentrated in a short time (2 hours) at the Yeongdong coastal area. The mechanism of thundersnow was investigated to describe in detail using observational data and numerical simulation (Weather Research and Forecast, WRF) applied lightning option. The results show that a convective cloud occurred at the Yeongdong coastal area. The east wind flow was generated and the pressure gradient force was maximized by the rapidly developed cyclone. The cold and dry air in the upper atmosphere has descended (so called tropopause folding) atmospheric lower layer at precipitation peak time (1200 LST). In addition, latent heat in the lower atmosphere layer and warm sea surface temperature caused thermal instability. The convective cloud caused by the strong thermal instability was developed up to 6 km at that time. And the backdoor cold front was determined by the change characteristics of meteorological elements and shear line in the east sea. Instability indexes such as Total totals Index (TT) and Lightning Potential Index (LPI) are also confirmed as one of good predictability indicates for the explosive precipitation of convective rainfall.

• Journal of Ginseng Research
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• v.40 no.3
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• pp.285-291
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• 2016

Background: Ginsenosides have been shown to exert beneficial pharmacological effects on the central nervous, cardiovascular, and endocrine systems. We sought to determine whether total ginsenosides (TG) inhibit monocrotaline (MCT)-induced pulmonary hypertension and to elucidate the underlying mechanism. Methods: MCT-intoxicated rats were treated with gradient doses of TG, with or without $N^G$-nitro-$\small{L}$-arginine methyl ester. The levels of molecules involving the regulation of nitric oxide and mitogen-activated protein kinase pathways were determined. Results: TG ameliorated MCT-induced pulmonary hypertension in a dose-dependent manner, as assessed by the right ventricular systolic pressure, the right ventricular hypertrophy index, and pulmonary arterial remodeling. Furthermore, TG increased the levels of pulmonary nitric oxide, endothelial nitric oxide synthase, and cyclic guanosine monophosphate. Lastly, TG increased mitogen-activated protein kinase phosphatase-1 expression and promoted the dephosphorylation of extracellular signal-regulated protein kinases 1/2, p38 mitogen-activated protein kinase, and c-Jun NH2-terminal kinase 1/2. Conclusion: TG attenuates MCT-induced pulmonary hypertension, which may involve in part the regulation of nitric oxide and mitogen-activated protein kinase pathways.