• Title/Summary/Keyword: Pressure Control Valve

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Effects of Remote Ischemic Pre-Conditioning to Prevent Contrast-Induced Nephropathy after Intravenous Contrast Medium Injection: A Randomized Controlled Trial

  • Dihia Belabbas;Caroline Koch;Segolene Chaudru;Mathieu Lederlin;Bruno Laviolle;Estelle Le Pabic;Dominique Boulmier;Jean-Francois Heautot;Guillaume Mahe
    • Korean Journal of Radiology
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    • v.21 no.11
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    • pp.1230-1238
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    • 2020
  • Objective: We aimed to assess the effects of remote ischemic pre-conditioning (RIPC) on the incidence of contrast-induced nephropathy (CIN) after an intravenous (IV) or intra-arterial injection of contrast medium (CM) in patient and control groups. Materials and Methods: This prospective, randomized, single-blinded, controlled trial included 26 patients who were hospitalized for the evaluation of the feasibility of transcatheter aortic valve implantation and underwent investigations including contrast-enhanced computed tomography (CT), with Mehran risk scores greater than or equal to six. All the patients underwent four cycles of five minute-blood pressure cuff inflation followed by five minutes of total deflation. In the RIPC group (n = 13), the cuff was inflated to 50 mm Hg above the patient's systolic blood pressure (SBP); in the control group (n = 13), it was inflated to 10 mm Hg below the patient's SBP. The primary endpoint was the occurrence of CIN. Additionally, variation in the serum levels of cystatin C was assessed. Results: One case of CIN was observed in the control group, whereas no cases were detected in the RIPC group (p = 0.48, analysis of 25 patients). Mean creatinine values at the baseline, 24 hours after injection of CM, and 48 hours after injection of CM were 88 ± 32 μmol/L, 91 ± 28 μmol/L and 82 ± 29 μmol/L, respectively (p = 0.73) in the RIPC group, whereas in the control group, they were 100 ± 36 μmol/L, 110 ± 36 μmol/L, and 105 ± 34 μmol/L, respectively (p = 0.78). Cystatin C values (median [Q1, Q3]) at the baseline, 24 hours after injection of CM, and 48 hours after injection of CM were 1.10 [1.08, 1.18] mg/L, 1.17 [0.97, 1.35] mg/L, and 1.12 [0.99, 1.24] mg/L, respectively (p = 0.88) in the RIPC group, whereas they were 1.11 [0.97, 1.28] mg/L, 1.13 [1.08, 1.25] mg/L, and 1.16 [1.03, 1.31] mg/L, respectively (p = 0.93), in the control group. Conclusion: The risk of CIN after an IV injection of CM is very low in patients with Mehran risk score greater than or equal to six and even in the patients who are unable to receive preventive hyperhydration. Hence, the Mehran risk score may not be an appropriate method for the estimation of the risk of CIN after IV CM injection.

Reliability Analysis on Safety Instrumented System by Using Safety Integrity Level for Fire.Explosion Prevention in the Ethyl Benzene Processes (Ethyl Benzene 공정에서 화재.폭발방지를 위하여 안전건전성수준을 이용한 안전장치시스템의 신뢰도 분석)

  • Ko, Jae-Sun;Kim, Hyo;Lee, Su-Kyoung
    • Fire Science and Engineering
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    • v.20 no.3 s.63
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    • pp.1-8
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    • 2006
  • The purpose of this work is to analyze quantitatively if the safety instrumented system(SIS) like the pressure safety valves(PSV) in the processes of ethyl benzene plant have been designed relevantly to the safety integrity level because overpressure in the benzene or ethyl benzene columns causes the explosive reactions, fires and reactor explosions. The safety integrity level(SIL) 3 has been adopted as a target level of SIS based on the general data of the Probability of Failure on Demand of PSV, $1.00E-4{\sim}1.00E-3$. The standard model of the reliability has been set up and then the fault tree analysis of it has been carried out to get the PFD of SIS, and the results show 8.97E-04, 5.37E-04, 5.37E-04 for benzene prefractionator column, benzene column and EB column, respectively. Thus, we conclude that the SIS is designed to fulfill the condition of SIL3, and when the partial stroke test for the control valve are carried out every sixth month, the SIS of each column is expected to increase its reliability up to $22{\sim}27%$.

A study on the inner flow fields characteristics of the Semi-active muffler (반능동형 머플러 내부의 유동장특성에 관한 연구)

  • Park Kyoung-Suk;Heo Hyung-Seok;Park Se-Jong;Son Sung-Man;Kim Dong-Hyun
    • Journal of the Korean Society for Precision Engineering
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    • v.23 no.3 s.180
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    • pp.125-131
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    • 2006
  • Recently air pollution has become an important issue. So, as tile number of vehicles increases, the noise pollution has become one of the most serious social issues nowadays. It is a muffler, which is one of the vehicle components. that has the hugest impact on the noise from the vehicle. And it also has a direct influence on the engine performance. So lately the research is proceeding on tile semi-active muffler which can control the back pressure variably by setting up the exhaust variable valve in the baffle to improve its internal structure. The inner parts of muffler which consist of a baffle, pipes and etc. appear to have the complicated turbulence phenomena by the pulsational wave of an unsteady state in the engine and by the structural characteristics of the inner parts. To analyze these phenomena, it is required to have an analysis of its constant quantity and quality. Therefore this study is to analyze with PIV measurement which can analyze the time and space variables, not with the point measurement method like former multi-point anemometer. It is to suggest proper design variables which need to make internal structure of the muffler improve though comparison between the passive type muffler and the semi-active muffler by fabricating a muffler which can be visualized.

Two-Dimensional Echocardiographic Preoperative Prediction of Prosthetic Valve Size (이면성 심초음파도로 구한 대동맥판륜부 크기와 실제 치환된 판막크기와의 비교연구)

  • 정태은
    • Journal of Chest Surgery
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    • v.21 no.6
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    • pp.979-983
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    • 1988
  • Calcium channel blockers may prevent myocardial injury during cardioplegia and reperfusion. This study was done to evaluate the effects of diltiazem cardioplegia on myocardial protection during ischemic arrest and recovery of myocardial function after reperfusion. Four formulations of crystalloid cardioplegic solutions, GIK solution[group I, n=12], diltiazem[lug/ml GIK] in GIK solution[group II, n=7], ],diltiazem[2ug/ml GIK] in GIK solution[group III, n=6] and diltiazem[4ug/ml GIK] in GIK solution[group IV, n=6] were compared in isolated working rat heart subjected to a long period [2 hours] of hypothermic arrest with multi-dose infusion. Diltiazem cardioplegia[group II, III and IV]was found to be superior in nearly all aspects. Diltiazem cardioplegia showed faster recovery of regular rhythm and lower incidence of ventricular fibrillation than group I did. In comparing mechanical function in all experimental hearts, the mean postischemic recoveries of aortic flow, cardiac output, peak aortic pressure, stroke volume and stroke work[expressed as a percentage of its preischemic control] were significantly greater in group II, III and IV[diltiazem cardioplegia] than in group I. The infused amount of cardioplegic solution was more increased by the addition of diltiazem to GI K solution. [p < 0.01] Creatine kinase leakage tended to be lower in hearts receiving diltiazem cardioplegia, especially in group III and IV[p<0.05] than in those receiving GIK solution only[group I]. Diltiazem cardioplegia results in the increased flow of cardioplegic solution and the decreased ischemic injury of myocardium during ischemic arrest and the improved recovery of myocardial function after reperfusion, and a dose-response relation must be established before clinical use.

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Development of PC-based Auto Inspection System for Smart Battery Protection Circuit Module (PC기반의 스마트 배터리 보호모듈 자동 검사 시스템 개발)

  • Yoon, Tae-Sung;Jang, Gi-Won;Park, Ju-No;Lee, Jeong-Jae
    • Proceedings of the KIEE Conference
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    • 2005.05a
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    • pp.275-277
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    • 2005
  • In a lithium-ion battery which is being used in many portable electronic goods, electrolyte is disaggregated and then the gas is happened when electric charging volt is over the 4.5V. So, the pressure on the safety valve is increased and electrolyte is leaked out in the cell. It leads to the risk of explosion. On the other hand, in the case which the battery is discharged excessively, the negative pole is damaged and the performance of the battery is deteriorated. The protection module of a lithium-ion battery is used for preventing such risk and the inspection system is needed to check the performance of such protection module. In this research, a PC-based auto inspection system is developed for the inspection of a battery protection module using Dallas chipset. In the inspection system, AVRl28 chip is used as a controller and the communication protocol is developed for the data communication between the protection module and the AVR128 chip. And GPIB interface is used for the control of measuring devices. Also, MMI environment is developed using LabView for convenient monitoring by the tester.

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Effect of composition and structure on exchange anisotropy of IrxMn(100-x)/NiFe films

  • Suh, Su-jung;Park, Young-suk;Ro, Jae-chul;Yong-sung;Yoon, Dae-ho
    • Proceedings of the Korea Association of Crystal Growth Conference
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    • 1998.06a
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    • pp.91-95
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    • 1998
  • Exchange anisotropy between IrMn antiferromagnetic layer and NiFe ferromagnetic layer has been studied in IrxMn(100-x)/NiFe/Buffr/Si(100) films deposited by D. C. magnetron sputtering method. Among Zr, Ta, and Cu used as buffer layer, Zr and Ta enhanced the fcc(111) texture of NiFe and IeMn layer, but Cu did not affect microstructure of those layer. Strong fcc(111) texture of IrMn layer was confirmed to be the origin of exchange anisotropy of IrMn. Ir composition control in IrMn layer showed that {{{{ gamma -phase}}}} IrMn is stabilized between 10 and 30 at % Ir, an 21 at. % Ir in IrMn layer was optimum composition that showed maximum exchange anisotropy field. above 200 ${\AA}$ thickness of IrMn, antiferromagnetic property is stabilzed to show saturated exchange anisotropy field. Based pressure was confirmed to be critical requisite in IrMn-based spin-valve GMR system.

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Study of Performance Optimization as an Alternative Refrigerant HFC152a in a Mobile Air Conditioning System (HFC152a 대체냉매를 이용한 자동차 냉방장치의 성능 최적화에 관한 연구)

  • Lee, Daewoong
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.27 no.6
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    • pp.321-327
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    • 2015
  • This study presents an HFC152a refrigerant air conditioner as an alternative to HFC134a, which is currently used in mobile air conditioning systems. Cool-down performance tests of an HFC152a air conditioning system were conducted and compared to a baseline HFC134a air conditioner. The experimental set-up consisted of a belt-driven compressor, a sub-cooled type condenser, an evaporator, and a block-type thermal expansion valve (TXV). A drop-in test was carried out on the mobile air conditioning system under various vehicle running speeds in a climate-controlled wind tunnel (CWT). Additionally, to optimize the HFC152a air conditioning system, the effects of the TXVs on the performance were studied. The results show that compared to the HFC134a air conditioning system, the refrigerant charge quantity was reduced by approximately 20%, the discharge pressure was reduced by about 350~430 kPa, and the air discharge temperature at vehicle running conditions was $0.5{\sim}1.5^{\circ}C$ lower. In addition, good compressor durability was expected due to the lower compression ratio.

A Study on the Simultaneous Reduction of NOx and Soot with Diesel-Methanol Stratified Injection System in a Diesel Engine (Part I : Design of Stratified Injection System and Combustion Characteristics of Stratified Injection) (층상연료분사(경유/메탄올)를 이용한 디젤엔진의 NOx와 Soot 동시 저감에 관한 연구 (제1보 : 층상분사장치의 설계 및 층상분사 연소특성))

  • Kang, B.M.;Kim, J.Y.;Lee, S.B.;Lee, T.W.;Ha, J.Y.
    • Journal of ILASS-Korea
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    • v.5 no.2
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    • pp.28-34
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    • 2000
  • To reduce the soot and NOx simultaneously, a new system of stratified injection is developed. This system discharges stratified diesel-methanol in a D. I. Diesel Engine. Nozzle and delivery valve of conventional injection system were remodeled to inject diesel and methanol from one injector sequently. The quantity of diesel and methanol was controled precisely by micrometers mounted on the injection control lack. The real injection ratio of dual fuel was measured by volumetric ratio. We could confirm the capabilities that soot and NOx simultaneously were reduced by diesel-methanol stratified injection from the results of in-cylinder pressure data obtained from combustion experiment by stratified injection, heat release rate and mass fraction bumed.

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A Flow Channel Design on IR Window Cooling Device (적외선 윈도우 냉각장치 유로 설계)

  • Park, Youn-Jung
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.39 no.6
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    • pp.559-566
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    • 2011
  • This paper presents the flow passage design for a window cooling device, which have a conical poppet valve and an emissive orifice. Computational flow analysis and experiment are conducted according to the poppet strokes. The results show satisfactory flow characteristics that pressure is reduced enough to endure material strength and the flow does not choked inside window. The correction factor of discharge coefficients is found between 2-dimensional analysis and experiments, which is applied to control coolant flow rates of the window cooling device.

Deduction of a Simplified Model for the Hydraulic Actuator for a Low-band Type Suspension System (능동제어식 현가계의 유압 구동장치에 대한 단순화 모델 유도)

  • 김동윤;홍예선;박영필
    • Transactions of the Korean Society of Automotive Engineers
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    • v.2 no.4
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    • pp.27-38
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    • 1994
  • In this paper, a simplified model of a hydraulic actuator system for a low-band type active suspension system is derived. To reduce the order of model, time constants of each chamber in hydraulic system are neglected except that of an accumulator. And the dynamics of a spool in the pressure control valve is regarded as a first-order system. The step response and the frequency response of the simplified second-order simulation model exhibit a good agreement with those of the actual system as well as those of the tenth-order simulation model. It is possible to simplify the tenth-order model to the second-order one. The low-band type active suspension model is built up by combining of a quarter car model test rig to testify the validity of the simplified model. The experimental results of suspension characteristics show that the simplified second-order hydraulic actuator model is reasonable to describe the dynamics of the actual hydraulic actuator system for a low-band type active suspension system.

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