• Title/Summary/Keyword: Presenting

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Cervical Fibrous Dysplasia Presenting as a Pathologic Fracture in an Older Patient

  • Lee, Su-Heon;Han, In-Ho;Kang, Dong-Wan;Choi, Byung-Kwan
    • Journal of Korean Neurosurgical Society
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    • v.50 no.2
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    • pp.139-142
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    • 2011
  • Vertebral involvement of fibrous dysplasia (FD) is rare, especially in the cervical spine. Moreover, cervical FD presenting as a pathologic fracture in older patients is extremely rare. We report a case of symptomatic cervical FD associated with pathologic fracture in a 63-year-old man. The patient presented with progressive weakness of the left arm and pain in the shoulder and arm. Radiologic studies revealed a collapsed and typical 'ground glass' radiolucency of C4. Multiple lytic lesions involved the odontoid process of C2 and the body, left pedicle, and posterior elements of C4. Combined anterior and posterior decompression and reconstruction were performed. Post-operatively, the histopathologic examination confirmed FD. On the post-operative follow-up examination, the neurologic deficits had completely resolved.

Bilateral Vertebral Artery Dissecting Aneurysms Presenting with Subarachnoid Hemorrhage Treated by Staged Coil Trapping and Covered Stents Graft

  • Yoon, Seok-Mann;Shim, Jai-Joon;Kim, Sung-Ho;Chang, Jae-Chil
    • Journal of Korean Neurosurgical Society
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    • v.51 no.3
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    • pp.155-159
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    • 2012
  • The treatment of bilateral vertebral artery dissecting aneurysms (VADAs) presenting with subarachnoid hemorrhage (SAH) is still challenging. The authors report a rare case of bilateral VADA treated with coil trapping of ruptured VADA and covered stents implantation after multiple unsuccessful stent assisted coiling of the contralateral unruptured VADA. A 44-year-old woman was admitted to our hospital because of severe headache and sudden stuporous consciousness. Brain CT showed thick SAH and intraventricular hemorrhage. Cerebral angiography demonstrated bilateral VADA. Based on the SAH pattern and aneurysm configurations, the right VADA was considered ruptured. This was trapped with endovascular coils without difficulty. One month later, the contralateral unruptured VADA was protected using a stent-within-a-stent technique, but marked enlargement of the left VADA was detected by 8-months follow-up angiography. Subsequently two times coil packing for pseudosacs resulted in near complete occlusion of left VADA. However, it continued to grow. Covered stents graft below the posterior inferior cerebellar artery (PICA) origin and a coronary stent implantation across the origin of the PICA resulted in near complete obliteration of the VADA. Covered stent graft can be used as a last therapeutic option for the management of VADA, which requires absolute preservation of VA flow.

Intramedullary Sarcoidosis Presenting with Delayed Spinal Cord Swelling after Cervical Laminoplasty for Compressive Cervical Myelopathy

  • Kwon, Du Ho;Lee, Sun-Ho;Kim, Eun-Sang;Eoh, Whan
    • Journal of Korean Neurosurgical Society
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    • v.56 no.5
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    • pp.436-440
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    • 2014
  • Sarcoidosis is a systemic disease of unknown etiology that may affect any organ in the body. The nervous system is involved in 5-16% of cases of sarcoidosis. Here, we report a case of intramedullary sarcoidosis presenting with delayed spinal cord swelling after laminoplasty for the treatment of compressive cervical myelopathy. A 56-year-old woman was admitted to our hospital complaining of upper extremity pain and gait disturbance. The patient had undergone laminoplasty for compressive cervical myelopathy 3 months previously. Follow-up magnetic resonance imaging revealed a large solitary intramedullary lesion with associated extensive cord swelling, signal changes, and heterogeneous enhancement of spinal cord from C2 to C7. Spinal cord biopsy revealed non-necrotizing granulomas with signs of chronic inflammation. The final diagnosis of sarcoidosis was based upon laboratory data, imaging findings, histological findings, and the exclusion of other diagnoses. Awareness of such presentations and a high degree of suspicion of sarcoidosis may help arrive at the correct diagnosis.

Progressive Manifestations of Reversible Cerebral Vasoconstriction Syndrome Presenting with Subarachnoid Hemorrhage, Intracerebral Hemorrhage, and Cerebral Infarction

  • Choi, Kyu-Sun;Yi, Hyeong-Joong
    • Journal of Korean Neurosurgical Society
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    • v.56 no.5
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    • pp.419-422
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    • 2014
  • Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by sudden-onset headache with focal neurologic deficit and prolonged but reversible multifocal narrowing of the distal cerebral arteries. Stroke, either hemorrhagic or ischemic, is a relatively frequent presentation in RCVS, but progressive manifestations of subarachnoid hemorrhage, intracerebral hemorrhage, cerebral infarction in a patient is seldom described. We report a rare case of a 56-year-old woman with reversible cerebral vasoconstriction syndrome consecutively presenting as cortical subarachnoid hemorrhage, intracerebral hemorrhage, and cerebral infarction. When she complained of severe headache with subtle cortical subarachnoid hemorrhage, her angiography was non-specific. But, computed tomographic angiography showed typical angiographic features of this syndrome after four days. Day 12, she suffered mental deterioration and hemiplegia due to contralateral intracerebral hematoma, and she was surgically treated. For recurrent attacks of headache, medical management with calcium channel blockers has been instituted. Normalized angiographic features were documented after 8 weeks. Reversible cerebral vasoconstriction syndrome should be considered as differential diagnosis of non-aneurysmal subarachnoid hemorrhage, and repeated angiography is recommended for the diagnosis of this under-recognized syndrome.

Differential Activation of T Cells by T-Cell Receptor Ligand Analogs

  • Choi, Yun-Hi;Suh, Yu-Jin;Kim, Kil-Hyoun
    • BMB Reports
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    • v.30 no.6
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    • pp.415-420
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    • 1997
  • Although $CD4^+$ T cell responses to protein-derived antigen have well been understood, the epitopes recognized by hapten-specific $CD4^+$ T cells have not been fully defined. In this study, we characterized the response of a T cell hybridoma (5Di0.1B8) which is specific for a hapten. N-hydroxysuccinimidyl-4-azidobenzoate (HSAB) restricted by MHC class II $I-A^d$. Using three different antigen presenting cells (APCs) expressing $I-A^d$, the role of class II MHC proteins in haptenic antigen presentation and subsequent activation of 5D10.1B8 has been examined. Activation of 5D10.1B8 T cells by HSAB analogs was also performed. Our results show that each APC activated T cells differentially and that interleukin-2 (IL-2) augmented antigen-presenting ability of all the APCs, suggesting that increased expression of class II MHC protein by IL-2 played an important role in HSAB presentation and T cell activation. Finally, early T cell receptor-dependent signals induced by HSAB or its analogs were examined by phosphotyrosine immunoblot analysis, and showed that tyrosine phosphorylation level of a 18-20 kD protein increased upon stimulation.

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CT and MRI Findings of Small Bowel Involvement of Amyloidosis Mimicking Small Bowel Polyposis Syndrome: a Case Report

  • Kang, Dong Min;Lee, Young Hwan;Kim, Youe Ree;Yoon, Kwon-Ha;Yun, Ki Jung
    • Investigative Magnetic Resonance Imaging
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    • v.24 no.2
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    • pp.85-89
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    • 2020
  • Amyloidosis is an all-inclusive disease of deposition of amyloid proteins in the extracellular spaces, which in localized or systemic form cause tissue damage and dysfunction. Herein, we report a case of small bowel involvement of systemic amyloidosis presenting with multiple polypoid wall thickening mimicking small bowel polyposis syndrome in an age 75 male. Interestingly, polypoid wall thickening and amyloidoma showed hypointensity on T2-weighted images. To our knowledge, there has been no literature describing MRI findings of poylpoid wall thickening and amyloidoma. Although the underlying mechanisms are unclear and need validation, hypointensity on T2-weighted images could be valuable in diagnosing small bowel involvement of amyloidosis in patients presenting with poylpoid wall thickening and amyloidoma.

A Study on the Embodying the Sense of Place in Children's Libraries (어린이 도서관에 있어서 장소성 구현에 관한 연구)

  • Lee, Jeong-Mi;Kwack, Dong-Wha;Cheon, Hye-Sun
    • Korean Institute of Interior Design Journal
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    • v.19 no.5
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    • pp.198-208
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    • 2010
  • The purpose of this study is to elicit the planning factors for the embodiment of sense of place in public library. This study analyzes qualitatively the good places where the children seek for and evaluate in children's library. The primary method of survey in this study is the caption evaluation. The survey is conducted in libraries of three types. In the caption evaluation, children take good places into photograph by themselves and are asked for reasons, features and physical characteristics for the pictures on good places. Through the study of the preceding studies, this study takes four analysis frames, Path, Occupancy Place, Edge and Mark. According to four analysis frames, the principal features, physical characteristics and the examples in libraries of domestic and foreign country are put in order. The meanings of this study are summarized as followings; presenting the method of user's positive evaluation, studying the sense of place in children's view point, and presenting the interrelation pattern for embodiment of the rich sense of place.

A Study on the Electronic Trade and eUCP (전자무역과 eUCP에 관한 연구)

  • Park, Sung-Chul
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.19
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    • pp.119-138
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    • 2003
  • ICC(International Chamber of Commerce) developed new rule on the presentation of electronic record in L/C transactions. This rule named as the e-UCP. The gists of this article are on the application of e-UCP in practice and it's some problems. The e-UCP is the supplement of current exisiting UCP but is superior to UCP under some circumstances. The e-UCP is only apply to the presentation of electronic record regardless of type of L/C(for example, traditional paper L/C or electronic L/C). The presentation of electronic record has some problems which has not seen in the presentation of paper document. These peblems are Time, Place of presentation, and format of electronic record and so on. The e-UCP provided on the basis of these problems. However, the e-UCP has some obscure provisions on the examination of electronic record and the corruption of electronic record. Who is responsible for the corruption of electronic record by the virus on the system of bank ? The current e-UCP is not clear on this matter. We have to note followings in case of presenting the documents electronically and applying the e-UCP. First, Beneficiary has additional duty to notice of completion of presentation. Second, It will be increasing the clean NEGO through prompt feedback of the descrepancy at the presenting time. Third, It is no use of L/G(Letter of Guarantee).

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Psychological Reduction Effect of Road Traffic Noise Perception by the Visual Information of Landscape components (조경요소의 영상을 이용한 도로교통소음 인지도의 심리적인 저감효과에 대한 연구)

  • Kook, Chan;Jang, Gil-Soo;Shin, Yong-kyu
    • KIEAE Journal
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    • v.3 no.2
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    • pp.33-36
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    • 2003
  • The influence of the visual information on the sound perception would be considerable. Furthermore, if the sound perception ranges in noisiness or annoyance beyond the loudness, it will depend much more on the shape of the visual information. This paper aims to estimate the influence of the several kinds of visual information on the perception of road traffic noise by means of the psycho-acoustic test method. The findings of present study on the influence of visual information on subjective noise perception are summarized as follows: Presenting visual images of mild and comfortable scenery reduced the noise perception reaction at the less noisy environments not exceeding 65 dB(A). At highly noisy environments exceeding 65 dB(A), however, the noise perception can be reduced by strong image of waterfall. Even eliminating the road traffic image may be helpful. Visual image of waterfall reduced the noise perception at all levels. It is inferred that the road traffic noise perception can be effectively ameliorated by presenting strong and real landscape images at any noisy environment.

Adaptive Changes in the Grain-size of Word Recognition (단어재인에 있어서 처리단위의 적응적 변화)

  • Lee, Chang H.
    • Proceedings of the Korean Society for Cognitive Science Conference
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    • 2002.05a
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    • pp.111-116
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    • 2002
  • The regularity effect for printed word recognition and naming depends on ambiguities between single letters (small grain-size) and their phonemic values. As a given word is repeated and becomes more familiar, letter-aggregate size (grain-size) is predicted to increase, thereby decreasing the ambiguity between spelling pattern and phonological representation and, therefore, decreasing the regularity effect. Lexical decision and naming tasks studied the effect of repetition on the regularity effect for words. The familiarity of a word from was manipulated by presenting low and high frequency words as well as by presenting half the stimuli in mixed upper- and lowercase letters (an unfamiliar form) and half in uniform case. In lexical decision, the regularity effect was initially strong for low frequency words but became null after two presentations; in naming it was also initially strong but was merely reduced (although still substantial) after three repetitions. Mixed case words were recognized and named more slowly and tended to show stronger regularity effects. The results were consistent with the primary hypothesis that familiar word forms are read faster because they are processed at a larger grain-size, which requires fewer operations to achieve lexical selection. Results are discussed in terms of a neurobiological model of word recognition based on brain imaging studies.

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