• Journal of Korean Neurosurgical Society
• /
• v.67 no.2
• /
• pp.237-248
• /
• 2024

Objective : Postoperative data on Cushing's disease (CD) are equivocal in the literature. These discrepancies may be attributed to different series with different criteria for remission and variable follow-up durations. Additional data from experienced centers may address these discrepancies. In this study, we present the results obtained from 96 endoscopic transsphenoidal surgeries (ETSSs) for CD conducted in a well-experienced center. Methods : Pre- and postoperative data of 96 ETSS in 87 patients with CD were included. All cases were handled by the same neurosurgical team between 2014 and 2022. We obtained data on remission status 3-6 months postoperatively (medium-term) and during the latest follow-up (long-term). Additionally, magnetic resonance imaging (MRI) and pathology results were obtained for each case. Results : The mean follow-up duration was 39.5±3.2 months. Medium and long-term remission rates were 77% and 82%, respectively. When only first-time operations were considered, the medium- and long-term remission rates were 78% and 82%, respectively. The recurrence rate in this series was 2.5%. Patients who showed remission between 3-6 months had higher long-term remission rates than did those without initial remission. Tumors >2 cm and extended tumor invasion of the cavernous sinus (Knosp 4) were associated with lower postoperative remission rates. Conclusion : Adenoma size and the presence/absence of cavernous sinus invasion on preopera-tive MRI may predict long-term postoperative remission. A tumor size of 2 cm may be a supporting criterion for predicting remission in Knosp 4 tumors. Further studies with larger patient populations are necessary to support this finding.

• Journal of Korean Library and Information Science Society
• /
• v.54 no.4
• /
• pp.307-334
• /
• 2023

The purpose of this study is to examine the status of data librarian-related course syllabi in the 2023 American Library Association(ALA)-accredited degree programs in Library and Information Science (LIS). The present study examined LIS course syllabi related to data librarian including course titles, course objectives, course descriptions, weekly topics and assignments. ALA-accredited LIS programs offer various courses in data librarianship such as data management and curation, data analysis and visualization, metadata, information services, research methods, library management, academic libraries, computer programming and databases. This study collected 184 syllabi from the ALA-accredited LIS programs and selected and analyzed 127 syllabi that are related to data librarianship. The study examined 3,045 course titles, 2,559 course description from 61 LIS degree programs overseas, and 1,330 course titles from 37 LIS degree programs in Korea. This study found that LIS degree programs both in Korea and overseas offer various courses for data librarians. The researcher hopes the findings of this study will be used as a starting point to develop or redesign courses related to data librarianship in the information field.

• Industry Promotion Research
• /
• v.9 no.1
• /
• pp.167-177
• /
• 2024

The purpose of this paper is to restore the academic status of Gungwi perception a little. The symbolism of Gungwi, or Year Month Day Hour, likened to Geun Myo Hwa Sil, is not just a technique of interpretation. Recognizing that it corresponds to Saju's most fundamental Mingli principle, the study was conducted to the effect that more academic research should be conducted in the future. The intrinsic idea that constitutes Saju is the yin-yang and the five elements, the letters recorded are twelve-dimensional, and the elements in charge of the space and time are Cheongan, Jeeji, and Gungwi, which are woven into four pillars. Through this consideration of Gungwi's perception, we presented the "spectrum of time" phenomenon that past time and information pass through the point of time, spread like a spectrum, and lead future time and action at the time when humans are born, that is, the energy of the universe is formatted throughout the brain and body. We discussed the change point of Eight Trigrams used by Lim Cheol Cho as a basis for explaining 'Won Hyong I Jeong' and the assumption that the time change or distortion of the two cones penetrating the present, which is assumed in parallel theory, one of the modern cosmologies, leaves an afterimage in the future universe as Gungwi's deductive basis.

• Journal of the Korean Society of Radiology
• /
• v.83 no.3
• /
• pp.473-485
• /
• 2022

The incidence of neurodegenerative diseases in the older population has increased in recent years. A considerable number of studies have been performed to characterize these diseases. Imaging analysis is an important biomarker for the diagnosis of neurodegenerative disease. Objective and reliable assessment and precise detection are important for the early diagnosis of neurodegenerative diseases. Artificial intelligence (AI) using brain MRI applied to the study of neurodegenerative diseases could promote early diagnosis and optimal decisions for treatment plans. MRI-based AI software have been developed and studied worldwide. Representatively, there are MRI-based volumetry and segmentation software. In this review, we present the development process of brain volumetry analysis software in neurodegenerative diseases, currently used and developed AI software for neurodegenerative disease in the Republic of Korea, probable uses of AI in the future, and AI software limitations.

• Journal of the Society of Disaster Information
• /
• v.20 no.1
• /
• pp.232-243
• /
• 2024

Purpose: Recently, large-scale forest fires caused by climate change, natural disasters, and human factors have been increasing every year in the East Coast and Taebaek Mountains region. Although forest fire extinguishing using helicopters is currently increasing, the need to introduce air force transport aircraft has continued to be raised due to the importance of early fire extinguishment to respond to large forest fires and the difficulty of extinguishing forest fires between sheep. This study seeks to present a plan for developing a post-fire management system for several aspects - achieving operational objectives, overcoming the operating environment, selecting a staging area, and efficient operation measures - to efficiently perform forest fire extinguishing missions using Air Force transport aircraft. Method: Based on literature research on forest fire extinguishing, forest fire extinguishing experiments using fixed-wing aircraft, and the operation status and operation method of forest fire extinguishing helicopters, the pros and cons of helicopter operation and the effects of large forest fire extinguishing using a large transport aircraft (C-130) Analyze the effectiveness of operation through analysis. Results: When extinguishing a large forest fire, an effective CM (Consequence Management) application plan was derived, including effective operation, control, command system, dispatch request, and forest fire extinguishment when integrating helicopter and fixed-wing aircraft (C-130). Conclusion: The application of the concept of CM (Consequence Management) is partially applied to some areas of chemical, biological, and radiological (CBRNE) protection in Korea, but efficient operation, control, and command systems are established when integrated operation of helicopters and large aircraft (C-130) in forest fire extinguishment. the concept of CM (Consequence Management), which is operated in advanced countries, was applied for safety management, dispatch requests, and forest fire extinguishing, thereby contributing to the establishment of a more advanced disaster and post-disaster management system.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.27 no.4
• /
• pp.258-265
• /
• 2024

Purpose: To date, there is no region-specific guideline for pediatric endoscopy training. This study aimed to illustrate the current status of pediatric endoscopy training in Asia-Pacific region and identify opportunities for improvement. Methods: A cross-sectional survey, using a standardized electronic questionnaire, was conducted among medical schools in the Asia-Pacific region in January 2024. Results: A total of 57 medical centers in 12 countries offering formal Pediatric Gastroenterology training programs participated in this regional survey. More than 75% of the centers had an average case load of <10 cases per week for both diagnostic and therapeutic endoscopies. Only 36% of the study programs employed competency-based outcomes for program development, whereas nearly half (48%) used volume-based curricula. Foreign body retrieval, polypectomy, percutaneous endoscopic gastrostomy, and esophageal variceal hemostasis, that is, sclerotherapy or band ligation (endoscopic variceal sclerotherapy and endoscopic variceal ligation), comprised the top four priorities that the trainees should acquire in the autonomous stage (unconscious) of competence. Regarding the learning environment, only 31.5% provided formal hands-on workshops/simulation training. The direct observation of procedural skills was the most commonly used assessment method. The application of a quality assurance (QA) system in both educational and patient care (Pediatric Endoscopy Quality Improvement Network) aspects was present in only 28% and 17% of the centers, respectively. Conclusion: Compared with Western academic societies, the limited availability of cases remains a major concern. To close this gap, simulation and adult endoscopy training are essential. The implementation of reliable and valid assessment tools and QA systems can lead to significant development in future programs.

• Oncology Letters
• /
• v.42 no.5
• /
• pp.2149-2158
• /
• 2019

Primary refractory acute myeloid leukemia (AML) and early recurrence of leukemic cells are among the most difficult hurdles to overcome in the treatment of AML. Moreover, uncertainties surrounding the molecular mechanism underlying refractory AML pose a challenge when it comes to developing novel therapeutic drugs. However, accumulating evidence suggests a contribution of phosphatase and tensin homolog (PTEN)/protein kinase B (AKT) signaling to the development of refractory AML. To assess PTEN/AKT signaling in AML, two types of AML cell lines were evaluated, namely control HL60 cells and KG1α cells, a refractory AML cell line that is resistant to idarubicin and cytarabine (AraC) treatment. Changes in the expression level of glycolysis- and mitochondrial oxidative phosphorylation-related genes and proteins were evaluated by reverse transcription-quantitative polymerase chain reaction and western blot analyses, respectively. The mitochondrial oxygen consumption and extracellular acidification rates were measured using an XF24 analyzer. CCK8 assay and Annexin V/PI staining were used to analyze cell viability and cellular apoptosis, respectively. The PTEN protein was found to be depleted, whereas AKT phosphorylation levels were elevated in KG1α cells compared with HL60 cells. These changes were associated with increased expression of glucose transporter 1 and hexokinase 2, and increased lactate production. AKT inhibition decreased the proliferation of KG1α cells and decreased extracellular acidification without affecting HL60 cells. Notably, AKT inhibition increased the susceptibility of KG1α cells to chemotherapy with idarubicin and AraC. Taken together, the findings of the present study indicate that activation of AKT by PTEN deficiency sustains the refractory AML status through enhancement of glycolysis and mitochondrial respiration, effects that may be rescued by inhibiting AKT activity.

• The Journal of the Convergence on Culture Technology
• /
• v.10 no.5
• /
• pp.827-832
• /
• 2024

The AI program Sora is a video production model that can be used innovatively and is the starting point of a major paradigm shift in video planning and production in the future. In this paper, through consideration of the characteristics, application, and process of the AI video production program, the characteristics of the AI design video production method were understood, and the production algorithm was considered. The detailed consideration and characteristics of the work creation process for the video graphic AI video generation program that will be intensified every year were examined. Next, the method of generating a customized video with a text prompt and the process of innovative production results different from the previous production method were considered. In addition, the design direction through the generation of AI images was studied through the review of the strengths and weaknesses of the image details of the recently announced AI music video results. By considering the security of the AI generation video Sora and looking at the internal process of the actual AI process, it will be possible to present indicators for the future direction of AI video model production and education along with the direction of the design designer and education system. In the text and conclusion, we analyzed the strengths and weaknesses and future status of OpenAI Sora image, concluded how to apply the Sora model's capabilities, limitations, quality, and human creativity, and presented problems and alternatives through examples of the Sora model's capabilities and limitations to increase human creativity.

• The Journal of the Convergence on Culture Technology
• /
• v.10 no.5
• /
• pp.219-227
• /
• 2024

The rapidly changing security environment and technological innovations of the 21st century present new challenges to military organizations. Particularly, as the MZ generation, comprised of Millennials (born 1981-1996) and Generation Z (born 1997-2012), emerges as the primary workforce in the military, traditional military personnel management methods are being called into question. The MZ generation, as digital natives, are technologically proficient, prioritize personal growth and quality of life, and prefer horizontal communication and participation. The purpose of this study is to reestablish talent acquisition and retention strategies for military organizations, considering the characteristics and demands of the MZ generation. To this end, we analyzed advanced talent management techniques from the corporate sector and explored ways to apply them to the unique context of military organizations. Additionally, by examining the current status and challenges of the Korean military, we attempted a balanced approach that considers both global trends and Korea's specific circumstances. The research results suggest various strategies including career development programs, cultural innovation, improvement of reward systems, participatory decision-making, enhancement of digital competencies, and creation of flexible work environments. These strategies are expected to improve the efficiency and competitiveness of military organizations while simultaneously enhancing job satisfaction and organizational commitment among MZ generation service members.

• Clean Technology
• /
• v.30 no.3
• /
• pp.175-187
• /
• 2024

Seaweeds are widely distributed along national coastlines around the world, and the biomass derived from them is an important marine biological organism. Seaweed is a crucial component of a healthy marine ecosystem. However, changes in marine environments have led to the occurrence of urchin barrens, and the damage caused by this phenomenon is steadily increasing. As a result, investigations into the distribution and spread of urchin barrens in the coastal areas of South Korea are being conducted regularly so efficient detection technologies are essential. One of the technologies that can swiftly and accurately analyze extensive areas is detection technology based on hyperspectral image information systems. This study aims to present the latest hyperspectral imaging technology for investigating the current status of urchin barrens and the methods for classifying this technology, including principles, preprocessing techniques, and correction methods. This study also proposes a classification technique for urchin barrens along the coast of Jeju Island that uses hyperspectral images and categorizes the urchin barrens into initial, intermediate, and advanced stages. The results showed that approximately 17.5% of the experimental areas were in the advanced stage. Based on this, various management and restoration methods tailored to different categories of urchin barren can be proposed.