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A Study of TNF-${\alpha}$(G308A) Genetic Polymorphism and Risk Factors Associated with Rheumatoid Arthritis by Sasang Constitution (사상체질에 따른 류마티스 관절염의 위해요인 및 TNF-${\alpha}$(G308A) 유전자 다형성간의 연관성 연구)

  • Kim, Su-Young;Chun, Hyung-Jon;Lee, Doo-Ik;Lee, Yun-Ho;Choi, Do-Young;You, Yong-Gu;Lee, Jae-Dong
    • Journal of Acupuncture Research
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    • v.24 no.1
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    • pp.137-159
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    • 2007
  • Objectives: The purpose of this study is to examine the risk factors and the genetic polymorphism of TNF-alpha associated with rheumatoid arthritis by Sasang constitution Methods : This study was planned to detect the susceptibility of the patients diagnosed by rheumatoid arthritis to Sasang Constitution and to examine the risk factor such as life style and environmental stress (smoking, environmental tobacco smoke, alcohol intake and so on). The genetic polymorphism of TNF-alpha (G308A) were analyzed by PCR-RFLP in rheumatoid arthritis patients and controls. Rheumatoid arthritis patients and matched controls are assessed with QSCCII question for Sasang Typology. Then the genetic polymorphism of patients by Sasang constitution are compared to those of control, which are statistically analyzed and adjusted by age, sex, smoking status, alcohol intake, BMI, and econocmic status. Results: Differential effect of passive smoking on the association between Sasang constitution and rheumatoid arthritis risk was found. This study showed that the genetic polymorphism (TNF-${\alpha}$(G308A)) of rheumatoid arthritis patients and controls associated with the susceptibility to rheumatoid arthritis by sasang constitution was analyzed. Differential effects of TNF-${\alpha}$(G308) genetic polymorphism on the association between rheumatoid arthritis risk and Sasang constitution were found. Conclusion : It is suggested that the genetic polymorphism correlated with susceptibility to rheumatoid arthritis by specific sasang constitution used as its susceptibility marker and further as basic data to prevent the risk factors for rheumatoid arthritis. But larger studies will be needed to confirm these preliminary findings.

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A Process Model for Virtual Collaboration: Theoretical Synthesis and Empirical Exploration (가상협업을 위한 프로세스 모형)

  • Suh, A-Young;Shin, Kyung-Shik
    • Asia pacific journal of information systems
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    • v.18 no.2
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    • pp.73-94
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    • 2008
  • When individuals collaborated in virtual settings, communication is medicated through a variety of communication technologies, and is associated not only with communication effectiveness but also with socio-emotional interactions among group members. In this regards, scholars have examined how technology-mediated communication systems can be designed and used to facilitated communication interaction. However, the empirical results of the previous studies have revealed inconsistencies in the effects of communication media on users' behavioral or attitudinal responses, and on their viable effectiveness in organizations. Some studies claim that computer-mediated communication(CMC) is task-oriented but not suitable for emotional expression since it hinders close interpersonal interaction. On the other hand, some studies argue that individuals are able to develop interpersonal relationships more effectively in a CMC environment than in an FtF-environment. Due to the different perspectives, a theoretical gap exists, and it leads to the inconsistent research findings. The purpose of this paper is to combine the two different perspectives into single unified model, thereby providing a more realistic and comprehensive understanding about virtual collaboration. The present study here sought to answers the following questions with organizational communication perspective: What are the major components of virtual collaboration? What factors affect the performance of virtual collaboration? And what kind of managerial efforts should organization make in order to facilitate CMC media effectiveness in virtual collaboration? Although there is a certain belief that new media, namely technology-mediated communication support would create new opportunities, the problem of "how" or "why" has been an important question that is still not fully addressed. In this regards, we collectively reexamined previous literatures with major issues which are still controversial and integrated various theoretical activity within computer-mediated communication domain: task-oriented approach, socio-emotional approach, and evolutionary psychological approach. Our first contribution is to develop a framework for virtual collaboration by combining two different perspectives into a single unified model, providing a more realistic and comprehensive understanding. The second main contribution is the joint modeling of both social presence and cognitive effort, and the effects on two distinct but important communication outcomes(i.e., take performance and relational development). We tested the research hypotheses which were developed based on the various CMC theories using data gathered through a self-administered mail survey of 127 individuals of 69 virtual workgroups. The proposed model was supported, providing preliminary evidence that the tension between two opposite view should be integrated. The results show that the individual's psychological processes(social presence and cognitive effort) in a virtual environment significantly mediated the effect of CMC inputs (media richness, user adaptation, and shared contest) on the CMC outputs (task performance and relational development). Furthermore, this study shows that the lack of perceived media richness of CMC media can be complemented by user adaptation and shared context. Based on the results, we discuss how communication system should be designed and implemented so as to promote virtual interaction as well as how a virtual workgroup should be composed to complement the lack of media richness. A virtual collaboration using CMC media may create new value by overcoming the logistical constraints. On the other hand, it may also generate various managerial risks such as communicational depersonalization, process dissatisfaction, and low cohesion. Therefore, this study suggests that organization managers should carefully choose the CMC mediums and monitor individual member's cognitive and affective psychological processes during virtual collaboration to reduce potential risks in virtual collaboration.

Perception Level of Nurses and Auxiliary Nurses for Radiological technologist (간호사와 간호조무사가 지각하는 방사선사 인식도)

  • Shin, Seong-Gyu
    • The Journal of the Korea Contents Association
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    • v.11 no.8
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    • pp.211-220
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    • 2011
  • The study conducted a survey on the perception level for radiological technologists with 321 nurses and auxiliary nurses working at university hospitals in Busan in order to supply preliminary data to enhance the status as well as professional images of radiological technologists. The result shows the perception level of $3.02{\pm}0.42$ with the highest score for the professional image and the lowest score for the business image. By question, 'they are professional' gets the highest score while 'they understand problems of patients well' gets the lowest. Among respondents, those who are well aware of education courses as well as leading organization of examination and who answer as a health care provider or a medical technician under the medical law show a high level of perception while those who answer as technician show a low perception level. Those who agree with radiologists as a career and consider their status as high in medical institutions have a high level of perception. In order to improve the perception level, individuals as well as associations' promotion and strategies are required to fix the title and enhance the negative images through active interests and kind attitudes toward patients. Also, efforts to escape from previous images limited to technical colleges, to vitalize academic conference and remedial education, and to frame the law of professional radiological technologists system are asked to heighten the qualification and status of radiological technologists. More than that, advertising and monitoring via mass media are needed to develop the image as professional career men as well.

Comparative analysis of two methods of laser induced boron isotopes separation

  • K.A., Lyakhov;Lee, H.J.
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.02a
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    • pp.407-408
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    • 2011
  • Natural boron consists of two stable isotopes 10B and 11B with natural abundance of 18.8 atom percent of 10B and 81.2 atom percent of 11B. The thermal neutron absorption cross-section for 10B and 11B are 3837 barn and 0.005 barn respectively. 10B enriched specific compounds are used for control rods and as a reactor coolant additives. In this work 2 methods for boron enrichment were analysed: 1) Gas irradiation in static conditions. Dissociation occurs due to multiphoton absorption by specific isotopes in appropriately tuned laser field. IR shifted laser pulses are usually used in combination with increasing the laser intensity also improves selectivity up to some degree. In order to prevent recombination of dissociated molecules BCl3 is mixed with H2S 2) SILARC method. Advantages of this method: a) Gas cooling is helpful to split and shrink boron isotopes absorption bands. In order to achieve better selectivity BCl3 gas has to be substantially rarefied (~0.01%-5%) in mixture with carrier gas. b) Laser intensity is lower than in the first method. Some preliminary calculations of dissociation and recombination with carrier gas molecules energetics for both methods will be demonstrated Boron separation in SILARC method can be represented as multistage process: 1) Mixture of BCl3 with carrier gas is putted in reservoir 2) Gas overcooling due to expansion through Laval nozzle 3) IR multiphoton absorption by gas irradiated by specifically tuned laser field with subsequent gradual gas condensation in outlet chamber It is planned to develop software which includes these stages. This software will rely on the following available software based on quantum molecular dynamics in external quantized field: 1) WavePacket: Each particle is treated semiclassicaly based on Wigner transform method 2) Turbomole: It is based on local density methods like density of functional methods (DFT) and its improvement- coupled clusters approach (CC) to take into account quantum correlation. These models will be used to extract information concerning kinetic coefficients, and their dependence on applied external field. Information on radiative corrections to equation of state induced by laser field which take into account possible phase transition (or crossover?) can be also revealed. This mixed phase equation of state with quantum corrections will be further used in hydrodynamical simulations. Moreover results of these hydrodynamical simulations can be compared with results of CFD calculations. The first reasonable question to ask before starting the CFD simulations is whether turbulent effects are significant or not, and how to model turbulence? The questions of laser beam parameters and outlet chamber geometry which are most optimal to make all gas volume irradiated is also discussed. Relationship between enrichment factor and stagnation pressure and temperature based on experimental data is also reported.

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Analysis of the Scientific Reasoning Ability of Science-Gifted 2nd Middle School Students in Open-Inquiry Activities (중학교 2학년 과학영재들의 자유탐구 활동에서 나타난 과학적 추론 능력 분석)

  • Lim, Sung-Chul;Kim, Jin-Hwa;Jeong, Jin-Woo
    • Journal of Science Education
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    • v.37 no.2
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    • pp.323-337
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    • 2013
  • The purpose of this study was to analyze the scientific reasoning ability during open-inquiry activities of science-gifted 2nd middle school students. Open-inquiry activity is similar to process of scientists' science knowledge generation. Identifying and analyzing the scientific reasoning process and the scientific reasoning ability during open-inquiry activities of science-gifted students, will be able to provide implications for future research. CSRI Matrix(Dolan & Grady, 2010) was used to analyze the complexity of the scientific reasoning ability. The higher degree of complexity of the scientific reasoning is similar to process of scientists' science knowledge generation. The results showed that each process of the open-inquiry activities were distributed by various steps of complexity of the scientific reasoning. Particularly, 'The generating questions' and 'Connecting data to the research question' were 'most complex' step in all teams. On the other side, 'Posing preliminary hypotheses', 'Selecting dependent and independent variables', 'Considering the limitations or flaws of their experiments' were low steps in most teams. And 'Communicating and defending findings' was distributed by most various steps of complexity of the scientific reasoning.

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Use of Smart Devices of Infants and Preschool-children and Their Mothers' Perceptions (영유아의 스마트기기 사용 실태 및 어머니의 인식)

  • Lee, Su Mi;Seo, Hyun Ah;Han, Hee Jung
    • Korean Journal of Childcare and Education
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    • v.10 no.2
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    • pp.111-131
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    • 2014
  • This study aims to research the use of smart devices of infants and preschool children, and their mothers' perception about it. Moreover, the goal of this study is to collect preliminary data about problems from the use of smart devices, and to prevent the problems. Therefore, the questions of inquiry for this study are: 1. How do infants and preschool children use smart devices? 2. How do mothers perceive their children using smart devices? Four hundred and forty mothers, who send their child to a day-care center or kindergarten in Busan, participated in this research and data among 397 of them were analyzed using PASW 18.0 program. The answers to a multiple-choice question were converted into a frequency and percentage. To verify the difference of factors, Chi-squared Test and One-way Analysis of Variance methods were used. The following are findings of this study: 1. Most of the families owning smart devices allow their children to use a smart device when children want it, and children use it for entertainment purpose before their bedtime. Children start to use a smart device mostly around the age of 4. Compared to girls, boys spend a longer time on smart devices playing mobile game. In addition, the research indicated that the children of younger mothers tend to use smart devices in earlier ages than the children of elder mothers. 2. Mothers of preschool children have higher perception about the availability of their child using smart devices compare to the mothers of day-care center. However, the research showed that elder mothers have more positive perceptions about all the other five lower factors, (e.g. educational characteristic, entertainment characteristic, design, safety, and smart recognition).

Development of the scale for recognition measurement of Home Economics Subject (가정교과의 인식 측정을 위한 척도 개발 연구)

  • Baek, Min-Kyung;Wang, Seok-Soon
    • Journal of Korean Home Economics Education Association
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    • v.24 no.2
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    • pp.101-116
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    • 2012
  • The purpose of this research is to develop a scale to measure how students and parents, who are the consumers of education, and home economics teachers and education experts, who are the suppliers, recognize the home economics subject, based on the characteristics and goal of the revised home economics curriculum that is currently being applied in South Korea, in the year 2007. To do this, the survey on home economics recognition developed and utilized in prior researches was used as the basic data. The final version of 60 questions was made by adding questions made through steps. They include question quality factor verification through step1-interview, step2-draft questions, step3-preliminary research, and step4-substantiation research of four groups. As a result of the factor analysis of the recognition of home economics, credibility is high in all factors. The final scale consists of 8 factors, when the explanatory power is 57.439%. This shows that home economics has been established as education for living and a practical subject. Nevertheless, it needs further improving to be recognized as a subject involving emphasis on healthy formation of family life and a subject of practical criticism.

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Analysis on Organization Performance Based on Hospital Culture (기독병원과 일반병원의 조직문화 특성에 따른 조직성과 분석)

  • Kim, Woon-Shin;Nam, Eun-Woo
    • Korea Journal of Hospital Management
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    • v.4 no.2
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    • pp.242-265
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    • 1999
  • Our study attempt is to see organizational performance according to the differences between types of hospital cultures. To determine theoretical relationship between the organizational culture and the performance, we select two hospitals in Pusan which are different in the purposes and shapes of establishment. We surveyed their members on a questionnaire based on the type of the organizational culture of the two institutions, analyzed, and review its organizational effectiveness. For the survey with questionnaires, which had been preliminary studied to raise its validity, question forms were distributed to 528 persons in April, 1999 based on the self-responses and recollected within 48 hours. The recollection rate was high(89.96%) and the quantity of questionnaires used for our final analysis was 430(81.44%). The Cronbach Coefficient Alpha of the questionnaires was 0.742. Regarding statistical techniques for analysis of the written materials, dispersion analysis(ANOVA) was adapted to test the organizational effectiveness of the two hospitals having the different organizational cultures, and Pearson Correlation was applied to determine correlations was among all variables. T-test was performed to test organizational effectiveness based on the differences in the extent of sharing the culture, organizational committment and work satisfaction between the two health institutions. From our analysis, we obtain the following conclusions. First, concerning with organizational culture of the two hospital, one of which is a christian hospital and the other is a private foundation hospital, the former is conservative and human-oriented but the latter focuses on renovation and accomplishment. Second, the private establishment has a relatively higher organizational effectiveness that the religious hospital as a result of analyzing the extent of sharing culture, organizational committment and work satisfaction. Third, it has been found that the correlations between the extent of the sharing culture and the organizational committment, the extent and work satisfaction, and the committment and the satisfaction are respectively positive influencing organizational effectiveness, especially work satisfaction. Fourth, cultural factors by which the christian hospital is affected more positively including human relations among its members, belief, its idea of establishment, tradition, work responsibility, power, and wage. On the other hand, factors such as director's leadership, personnel management, wage, hospital regulations and department managers' management ability have been seen as negative influences in order. And fifth, for the private foundation hospital human relations among its members, wages, work responsibility, director's leadership and department managers' management ability were positive in their sequence while wages, personnel management, hospital regulations, welfare and department managers' management ability were considered as negative influences in order. As these results of this study, the higher extent of sharing organizational culture, the more increasing in both organization committment and work satisfaction, the higher the effectiveness. Although it was somewhat difficult to generalize the results whose subjects were the two hospitals only, it was obvious that organizational culture was an important influential factor of organizational effectiveness. It is questionable that the extent of sharing organizational culture, organizational committment and work satisfaction as variables affecting the effectiveness have their validity, but this study has its significance in that it provided an approaching to evaluate the organizational culture of individual hospitals making allowances for such variables related to the general activities in its hospital. We hope the results of the study could be useful for the managerial strategies of the institutions.

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A Study on Marine Accident Ontology Development and Data Management: Based on a Situation Report Analysis of Southwest Coast Marine Accidents in Korea (해양사고 온톨로지 구축 및 데이터 관리방안 연구: 서해남부해역 선박사고 상황보고서 분석을 중심으로)

  • Lee, Young Jai;Kang, Seong Kyung;Gu, Ja-Yeong
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.25 no.4
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    • pp.423-432
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    • 2019
  • Along with an increase in marine activities every year, the frequency of marine accidents is on the rise. Accordingly, various research activities and policies for marine safety are being implemented. Despite these efforts, the number of accidents are increasing every year, bringing their effectiveness into question. Preliminary studies relying on annual statistical reports provide precautionary measures for items that stand out significantly, through the comparison of statistical provision items. Since the 2000s, large-scale marine accidents have repeatedly occurred, and case studies have examined the "accident response." Likewise, annual statistics or accident cases are used as core data in policy formulation for domestic maritime safety. However, they are just a summary of post-accident results. In this study, limitations of current marine research and policy are evaluated through a literature review of case studies and analyses of marine accidents. In addition, the ontology of the marine accident information classification system will be revised to improve the current limited usage of the information through an attribute analysis of boating accident status reports and text mining. These aspects consist of the reporter, the report method, the rescue organization, corrective measures, vulnerability of response, payloads, cause of oil spill, damage pattern, and the result of an accident response. These can be used consistently in the future as classified standard terms to collect and utilize information more efficiently. Moreover, the research proposes a data collection and quality assurance method for the practical use of ontology. A clear understanding of the problems presently faced in marine safety will allow "suf icient quality information" to be leveraged for the purpose of conducting various researches and realizing effective policies.

Development of Community Resources Linkage Capability Scale of Counselors (심리상담사의 지역사회자원연계 능력 척도 개발)

  • Seong, Seul-Ah;Bae, Seong-Hoon
    • Korean Journal of School Psychology
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    • v.17 no.3
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    • pp.357-377
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    • 2020
  • This study was intended to develop and investigate reliability and validity of a scale that can measure linkage capability of community resources of counselors. This study prepared a preliminary question consisting of a total of 42 questions in 5 areas. Then, the content validity and facial validity were verified by the counseling experts with a first-degree qualification as a counselor in Korean Counselling Psychological Association, and a total of 20 final questions of 4 areas. The final questions were conducted on psychological counselors(N=306) to investigate reliability and validity. As a result of conducting an exploratory factor analysis, validity of the two-factor structure have been verified. And In the confirmatory factor analysis, two factors were shown to be appropriate. The two-factors were named 'The collection and utilization of information' and 'Association with the Organization of Information'. Also, the scale of final selection of questions were found to have a good degree of concurrent validity, interitem consistency and test-retest reliability. The implications of the present study is significant in that it is a measure of community resources linkage capability scale of counselors. In addition, this scale is expected to be useful in Wee Class, Wee Center, Youth Counseling Welfare Center, and other counseling sites.