• Title/Summary/Keyword: Predictive ability

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Comparison of Partial Least Squares and Support Vector Machine for the Autoignition Temperature Prediction of Organic Compounds (유기물의 자연발화점 예측을 위한 부분최소자승법과 SVM의 비교)

  • Lee, Gi-Baek
    • Journal of the Korean Institute of Gas
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    • v.16 no.1
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    • pp.26-32
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    • 2012
  • The autoignition temperature is one of the most important physical properties used to determine the flammability characteristics of chemical substances. Despite the needs of the experimental autoignition temperature data for the design of chemical plants, it is not easy to get the data. This study have built and compared partial least squares (PLS) and support vector machine (SVM) models to predict the autoignition temperatures of 503 organic compounds out of DIPPR 801. As the independent variables of the models, 59 functional groups were chosen based on the group contribution method. The prediction errors calculated from cross-validation were employed to determine the optimal parameters of two models. And, particle swarm optimization was used to get three parameters of SVM model. The PLS and SVM results of the average absolute errors for the whole data range from 58.59K and 29.11K, respectively, indicating that the predictive ability of the SVM is much superior than PLS.

Prediction models of compressive strength and UPV of recycled material cement mortar

  • Wang, Chien-Chih;Wang, Her-Yung;Chang, Shu-Chuan
    • Computers and Concrete
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    • v.19 no.4
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    • pp.419-427
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    • 2017
  • With the rising global environmental awareness on energy saving and carbon reduction, as well as the environmental transition and natural disasters resulted from the greenhouse effect, waste resources should be efficiently used to save environmental space and achieve environmental protection principle of "sustainable development and recycling". This study used recycled cement mortar and adopted the volumetric method for experimental design, which replaced cement (0%, 10%, 20%, 30%) with recycled materials (fly ash, slag, glass powder) to test compressive strength and ultrasonic pulse velocity (UPV). The hyperbolic function for nonlinear multivariate regression analysis was used to build prediction models, in order to study the effect of different recycled material addition levels (the function of $R_m$(F, S, G) was used and be a representative of the content of recycled materials, such as fly ash, slag and glass) on the compressive strength and UPV of cement mortar. The calculated results are in accordance with laboratory-measured data, which are the mortar compressive strength and UPV of various mix proportions. From the comparison between the prediction analysis values and test results, the coefficient of determination $R^2$ and MAPE (mean absolute percentage error) value of compressive strength are 0.970-0.988 and 5.57-8.84%, respectively. Furthermore, the $R^2$ and MAPE values for UPV are 0.960-0.987 and 1.52-1.74%, respectively. All of the $R^2$ and MAPE values are closely to 1.0 and less than 10%, respectively. Thus, the prediction models established in this study have excellent predictive ability of compressive strength and UPV for recycled materials applied in cement mortar.

Bayesian Survival Analysis of High-Dimensional Microarray Data for Mantle Cell Lymphoma Patients

  • Moslemi, Azam;Mahjub, Hossein;Saidijam, Massoud;Poorolajal, Jalal;Soltanian, Ali Reza
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.1
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    • pp.95-100
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    • 2016
  • Background: Survival time of lymphoma patients can be estimated with the help of microarray technology. In this study, with the use of iterative Bayesian Model Averaging (BMA) method, survival time of Mantle Cell Lymphoma patients (MCL) was estimated and in reference to the findings, patients were divided into two high-risk and low-risk groups. Materials and Methods: In this study, gene expression data of MCL patients were used in order to select a subset of genes for survival analysis with microarray data, using the iterative BMA method. To evaluate the performance of the method, patients were divided into high-risk and low-risk based on their scores. Performance prediction was investigated using the log-rank test. The bioconductor package "iterativeBMAsurv" was applied with R statistical software for classification and survival analysis. Results: In this study, 25 genes associated with survival for MCL patients were identified across 132 selected models. The maximum likelihood estimate coefficients of the selected genes and the posterior probabilities of the selected models were obtained from training data. Using this method, patients could be separated into high-risk and low-risk groups with high significance (p<0.001). Conclusions: The iterative BMA algorithm has high precision and ability for survival analysis. This method is capable of identifying a few predictive variables associated with survival, among many variables in a set of microarray data. Therefore, it can be used as a low-cost diagnostic tool in clinical research.

Comparison of Predict Mortality Scoring Systems for Spontaneous Intracerebral Hemorrhage Patients (자발성 뇌내출혈 환자의 예후 예측도구 비교)

  • Youn, Bock-Hui;Kim, Eun-Kyung
    • Korean Journal of Adult Nursing
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    • v.17 no.3
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    • pp.464-473
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    • 2005
  • Purpose: The purpose of this study was to evaluate and compare the predictive ability of three mortality scoring systems; Acute Physiology and Chronic Health Evaluation(APACHE) III, Simplified Acute Physiology Score(SAPS) II, and Mortality Probability Model(MPM) II in discriminating in-hospital mortality for intensive care unit(ICU) patients with spontaneous intracerebral hemorrhage. Methods: Eighty-nine patients admitted to the ICU at a university hospital in Daejeon Korea were recruited for this study. Medical records of the subject were reviewed by a researcher from January 1, 2003 to March 31, 2004, retrospectively. Data were analyzed using SAS 8.1. General characteristic of the subjects were analyzed for frequency and percentage. Results: The results of this study were summarized as follows. The values of the Hosmer-Lemeshow's goodness-of-fit test for the APACHE III, the SAPS II and the MPM II were chi-square H=4.3849 p=0.7345, chi-square H=15.4491 p=0.0307, and chi-square H=0.3356 p=0.8455, respectively. Thus, The calibration of the MPM II found to be the best scoring system, followed by APACHE III. For ROC curve analysis, the areas under the curves of APACHE III, SAPS II, and MPM II were 0.934, 0.918 and 0.813, respectively. Thus, the discrimination of three scoring systems were satisfactory. For two-by-two decision matrices with a decision criterion of 0.5, the correct classification of three scoring systems were good. Conclusion: Both the APACHE III and the MPM II had an excellent power of mortality prediction and discrimination for spontaneous intracerebral hemorrhage patients in ICU.

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Forecasting of Chestnut's Supply and Demand by the Partial Equilibrium Market Model (부분균형 시장모델에 의한 밤 수급 예측)

  • Jung, Byung Heon;Kim, Eui Gyeong;Joo, Rin Won
    • Journal of Korean Society of Forest Science
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    • v.97 no.4
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    • pp.458-466
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    • 2008
  • This study was carried out to forecast long-term supply and demand of chestnut and to analyze the impacts of change in the environment of domestic and international chestnut markets. For these ends, the study developed a partial equilibrium market model, in which in-shelled chestnut market was vertically linked to shelled chestnut market. To examine the predictive ability of the model for the endogenous variables ex-post simulation was run for the period 1990 through 2003. In general, all endogenous variables reproduced the historical trends during the period except for disuse areas and newly established areas. The results of forecasting supply and demand show that domestic in-shelled chestnut production is estimated to decrease slightly from 76,447 ton in 2005 to 76,286 ton in 2020 and that exports of shelled chestnut continue to be decreased.

Large Eddy Simulation of Swirling Premixed Flames in a Model Gas Turbine Combustor (모형 가스터빈 연소기에서 선회 예혼합화염의 대와동모사(LES))

  • 황철홍;이창언
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.34 no.7
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    • pp.79-88
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    • 2006
  • In the present paper, the swirl flow structure and flame characteristics of turbulent premixed combustion in a model gas turbine combustor are investigated using large eddy simulation(LES). A G-equation flamelet model is employed to simulate the unsteady flame behavior. When inlet swirl number is increased, the distinct flow structures, such as the shapes of corner recirculation and center toroidal recirculation zone, are observed and the flame length is shorted gradually. Also, the phenomena of flashback are identified at strong swirl intensity. In order to get the accurate description of unsteady flame behavior, the predictive ability of the acoustic wave in a combustor is primarily evaluated. It is found that the vortex generated near the edge of step plays an important role in the flame fluctuation. Finally it is examined systematically that the flame and heat release fluctuation are coupled strongly to the vortex shedding generated by swirl flow and acoustic wave propagation from the analysis of flame-vortex interaction.

A Comparative Study on Comorbidity Measurements with Lookback Period using Health Insurance Database: Focused on Patients Who Underwent Percutaneous Coronary Intervention (건강보험 청구자료에서 동반질환 보정방법과 관찰기관 비교 연구: 경피적 관상동맥 중재술을 받은 환자를 대상으로)

  • Kim, Kyoung-Hoon;Ahn, Lee-Su
    • Journal of Preventive Medicine and Public Health
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    • v.42 no.4
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    • pp.267-273
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    • 2009
  • Objectives : To compare the performance of three comorbidity measurements (Charlson comorbidity index, Elixhauser s comorbidity and comorbidity selection) with the effect of different comorbidity lookback periods when predicting in-hospital mortality for patients who underwent percutaneous coronary intervention. Methods : This was a retrospective study on patients aged 40 years and older who underwent percutaneous coronary intervention. To distinguish comorbidity from complications, the records of diagnosis were drawn from the National Health Insurance Database excluding diagnosis that admitted to the hospital. C-statistic values were used as measures for in comparing the predictability of comorbidity measures with lookback period, and a bootstrapping procedure with 1,000 replications was done to determine approximate 95% confidence interval. Results : Of the 61,815 patients included in this study, the mean age was 63.3 years (standard deviation: ${\pm}$10.2) and 64.8% of the population was male. Among them, 1,598 2.6%) had died in hospital. While the predictive ability of the Elixhauser's comorbidity and comorbidity selection was better than that of the Charlson comorbidity index, there was no significant difference among the three comorbidity measurements. Although the prevalence of comorbidity increased in 3 years of lookback periods, there was no significant improvement compared to 1 year of a lookback period. Conclusions : In a health outcome study for patients who underwent percutaneous coronary intervention using National Health Insurance Database, the Charlson comorbidity index was easy to apply without significant difference in predictability compared to the other methods. The one year of observation period was adequate to adjust the comorbidity. Further work to select adequate comorbidity measurements and lookback periods on other diseases and procedures are needed.

EXPRESSION OF E-CADHERIN WITH CORRELATION TO CLINICOPATHOLOGIC PARAMETERS IN ORAL SQUAMOUS CELL CARCINOMA (구강 편평세포암종에서 E-cadherin의 발현과 임상병리학적 지표와의 관계)

  • Shin, Jae-Myoung;Kim, Young-Sill;Kim, Chang-Hyen;Pyo, Sung-Woon
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.31 no.1
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    • pp.1-6
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    • 2005
  • It becomes more concerned that the cell adhesion molecule plays an important role in the process of malignant transformation and tumor behaviors including invasive growth and metastasis. It is postulated if the expression of adhesion molecule is reduced in tumor tissue, the tumor cell will be undifferentiated and lose their cell adhesion ability and polarity. So the tumor cells lost the adhesion of cell to cell and to basement membrane that they became more aggressive. Reduced cadherin expression enhances invasiveness through infiltrative growth and metastasis of tumor cells is well known and mostly accepted in many epithelia tumors. We explored the expression of E-cadherin by immunohistochemical staining in 50 oral squamous cell carcinomas and investigated the correlation between the expression of E-cadherin and clinicopathologic parameters and prognosis. The expression of E-cadherin was reduced in 40/50(80%) of primary tumors, and 21/22(95.5%) of lymph nodes. The reduced expression of the E-cadherin was associated with lymph node metastasis(P=0.029), invasive mode(P=0.030) and marginal status(P=0.038). Survival analysis showed that predictive period of E-cadherin reduced group(37 months) was lower than that of E-cadherin preserved group(60 months), but there was no statistical significant difference.

Design of Monitoring System based on IoT sensor for Health Management of an Elderly Alone

  • Hur, Hwa-La;Park, Myeong-Chul
    • Journal of the Korea Society of Computer and Information
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    • v.25 no.8
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    • pp.81-87
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    • 2020
  • In this paper, proposes a health status monitoring system for socially marginalized elderly households living alone. This system is implemented by collecting various PHR biometric signals and residential environment information through IoT devices. In addition, the company aims to establish a basic infrastructure that can understand the situation of lonely deaths and implement prevention programs by strengthening the predictive ability through data analysis of the DB server based on PHR and information collected from IoT sensors. The sensor consists of an environmental information collection sensor and a noncontact and wearable sensor for biometric signal collection. A gateway is required to transmit the collected data to the server, and the prototype is presented in this paper. The paper has a discussion purpose of policy task for expanding medical welfare service. The results of this study are believed to help expand services to the socially marginalized and improve the medical environment of the people.

Modeling the potential climate change-induced impacts on future genus Rhipicephalus (Acari: Ixodidae) tick distribution in semi-arid areas of Raya Azebo district, Northern Ethiopia

  • Hadgu, Meseret;Menghistu, Habtamu Taddele;Girma, Atkilt;Abrha, Haftu;Hagos, Haftom
    • Journal of Ecology and Environment
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    • v.43 no.4
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    • pp.427-437
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    • 2019
  • Background: Climate change is believed to be continuously affecting ticks by influencing their habitat suitability. However, we attempted to model the climate change-induced impacts on future genus Rhipicephalus distribution considering the major environmental factors that would influence the tick. Therefore, 50 tick occuance points were taken to model the potential distribution using maximum entropy (MaxEnt) software and 19 climatic variables, taking into account the ability for future climatic change under representative concentration pathways (RCPs) 4.5 and 8.5, were used. Results: MaxEnt model performance was tested and found with the AUC value of 0.99 which indicates excellent goodness-of-fit and predictive accuracy. Current models predict increased temperatures, both in the mid and end terms together with possible changes of other climatic factors like precipitation which may lead to higher tick-borne disease risks associated with expansion of the range of the targeted tick distribution. Distribution maps were constructed for the current, 2050, and 2070 for the two greenhouse gas scenarios and the most dramatic scenario; RCP 8.5 produced the highest increase probable distribution range. Conclusions: The future potential distribution of the genus Rhipicephalus show potential expansion to the new areas due to the future climatic suitability increase. These results indicate that the genus population of the targeted tick could emerge in areas in which they are currently lacking; increased incidence of tick-borne diseases poses further risk which can affect cattle production and productivity, thereby affecting the livelihood of smallholding farmers. Therefore, it is recommended to implement climate change adaptation practices to minimize the impacts.