• Title/Summary/Keyword: Prediction of variables

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Expression of lipid metabolism genes provides new insights into intramuscular fat deposition in Laiwu pigs

  • Wang, Hui;Wang, Jin;Yang, Dan-dan;Liu, Zong-li;Zeng, Yong-qing;Chen, Wei
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.3
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    • pp.390-397
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    • 2020
  • Objective: The objective of this study was to measure the special expression pattern of lipid metabolism genes and investigate the molecular mechanisms underlying intramuscular fat (IMF) deposition in Longissimus dorsi muscle of Laiwu pigs. Methods: Thirty-six pigs (Laiwu n = 18; Duroc×Landrace×Yorkshire n = 18) were used for the measurement of the backfat thickness, marbling score, IMF content, and expression of lipid metabolism genes. Results: Significant correlations were found between IMF content and the mRNA expression of lipid metabolism genes. Of the 14 fat deposition genes measured, fatty acid synthase (FASN) showed the strongest correlation (r = 0.75, p = 0.001) with IMF content, and of the 6 fat removal genes, carnitine palmitoyl transferase 1B (CPT1B) exhibited the greatest negative correlation (r = -0.66, p = 0.003) with IMF content in Laiwu pig. Multiple regression analysis showed that CPT1B, FASN, solute carrier family 27 member 1 (SLC27A1), and fatty acid binding protein 3 (FABP3) contributed 38% of the prediction value for IMF content in Laiwu pigs. Of these four variables, CPT1B had the greatest contribution to IMF content (14%) followed by FASN (11%), SLC27A1 (9%), and FABP3 (4%). Conclusion: Our results indicate that the combined effects of an upregulation in fat deposition genes and downregulation in fat removal genes promotes IMF deposition in Laiwu pigs.

Measurement of the Early-Age Coefficient of Thermal Expansion and Drying Shrinkage of Concrete Pavement (콘크리트포장의 초기 열팽창계수 및 건조수축 측정 연구)

  • Yoon, Young-Mi;Suh, Young-Chan;Kim, Hyung-Bae
    • International Journal of Highway Engineering
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    • v.10 no.1
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    • pp.117-122
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    • 2008
  • Quality control of the concrete pavement in the early stage of curing is very important because it has a conclusive effect on its life span. Therefore, examining and analyzing the initial behavior of concrete pavement must precede an alternative to control its initial behavior. There are largely two influential factors for the initial behavior of concrete pavement. One is the drying shrinkage, and the other is the heat generated by hydration and thermal change inside the pavement depending on the change in the atmospheric temperature. Thus, the coefficient of thermal expansion and drying shrinkage can be regarded as very important influential factors for the initial behavior of the concrete. It has been a general practice up until now to measure the coefficient of thermal expansion from completely cured concrete. This practice has an inherent limitation in that it does not give us the coefficient of thermal expansion at the initial stage of curing. Additionally, it has been difficult to obtain the measurement of drying shrinkage due to the time constraint. This research examined and analyzed the early drying shrinkage of the concrete and measurements of the thermal expansion coefficients to formulate a plan to control its initial behavior. Additionally, data values for the variables of influence were collected to develop a prediction model for the initial behavior of the concrete pavement and the verification of the proposed model. In this research, thermal expansion coefficients of the concrete in the initial stage of curing ranged between $8.9{\sim}10.8{\times}10^{-6}/^{\circ}C$ Furthermore, the effects of the size and depth of the concrete on the drying shrinkage were analyzed and confirmed.

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Prediction Model of Fatigue in Women with Rheumatoid Arthritis (여성 류마티스 관절염 환자의 피로 예측 모형)

  • Lee, Kyung-Sook;Lee, Eun-Ok
    • Journal of muscle and joint health
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    • v.8 no.1
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    • pp.27-50
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    • 2001
  • Rheumatoid arthritis is a chronic systemic autoimmune disease. Although the joints are the major loci of the disease activity, fatigue is a common extraarticular symptom that exists in all gradations of rheumatoid arthritis. Fatigue is defined as a subjective sense of generalized tiredness or exhaustion and has multiple dimensions. Therefore fatigue is a common and frequent problem for those with rheumatoid arthritis. In fact, 88-100% of individuals with rheumatoid arthritis experience fatigue. Especially the degree of fatigue is higher in women than men with rheumatoid arthritis. Despite the importance of fatigue among the patients with rheumatoid arthritis, the mechanism that leads to fatigue in rheumatoid arthritis is not completely understood. This study was intended to test and validate a model to predict fatigue in women with rheumatoid arthritis. Especially it was intended to identify the direct and indirect effects of the variables of pain, disability, depression, sleep disturbance, morning stiffness, and symptom duration to fatigue. Data were collected by questionnaires including Multidimensional Assesment of Fatigue(Tack, 1991), numeric scale of pain, graphic scale of joints, Ritchie Articular Index, Korean Health Assessment Questionnaire(Bae, et al., 1998), Inventory of Function Status(Tulman, et al., 1991), Center for Epidemiologic Studies-Depression, and Korean Sleep Scale(Oh, et al 1998). The sample consisted of 345 women with a mean duration of rheumatoid arthritis for 10.06 years and a mean age of 49.64 years. SPSS win and Win LISREL were used for the data analysis. Structural equation modeling revealed the overall fit of the model. Pain predicted fatigue directly and indirectly through disability, depression, and sleep disturbance. Disability, sleep disturbance predicted fatigue only directly, while depression only indirectly through disability and sleep disturbance. Also morning stiffness and symptom duration predicted fatigue through disability and depression. All predictors accounted for 65% of the variance of fatigue. Depression, pain, and disability predicted sleep disturbance. Depression had reciprocal relationship with disability and they both were predicted by pain directly and indirectly. In summary, pain, depression, disability, sleep disturbance, morning stiffness, and symptom duration contributed to the fatigue of patients with rheumatoid arthritis. The best predictor of fatigue was pain. This finding indicates that the modification of pain, depression, disability, sleep disturbance, morning stiffness could be nursing intervention for relief or prevention of fatigue.

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A study on factors affecting the job satisfaction of dental hygienists in Gwangju (광주광역시 치과위생사의 직무만족도에 영향을 주는 요인에 대한 연구)

  • Youn, Hye-Jeong;Park, Young-Nam;Ha, Myung-Ok
    • Journal of Korean society of Dental Hygiene
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    • v.9 no.4
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    • pp.699-714
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    • 2009
  • Objectives : This study was to examine factors affecting the job satisfaction of dental hygienists. Methods : The subjects in this study were dental hygienists who worked at dental hospitals, dental clinics and general hospitals in the city of Gwangju. A survey was conducted by mail from January 2 to March 2, 2007. Out of the collected data, 208 answer sheets were analyzed. Results : 1. The dental hygienists investigated got a mean of 3.20 on job satisfaction. Among the job satisfaction factors, relationship with patients ranked highest(3.79), followed by relationship with colleagues(3.62), working environments(3.39), future prospects(3.30), professional status (2.89), pay(2.82) and required workload(2.58). 2. Regarding links between general characteristics and job satisfaction, the older dental hygienists were more satisfied with professional status, pay, required workload and relationship with patients. By marital status, the married dental hygienists expressed better satisfaction at professional status than the unmarried ones. By education, those who were receiving college education or received the same or higher education were more gratified than the junior college graduates. By the total length of career, the dental hygienists whose length of career was longer were more gratified with professional status, future prospects and relationship with patients. By workplace, the dental hospital workers were more satisfied with working environments, and the general hospital employees were more gratified with pay. The dental hospital employees were better satisfied with future prospects as well. As to the impact of the length of career at the current workplace, there was a tendency that those who worked at their current workplaces for a longer time expressed better satisfaction with professional status, pay and relationship with patients. By monthly mean income, the larger income earners had a tendency to be better gratified with professional status, pay and relationship with patients. 3. The general characteristics that were selected as independent variables were identified as the factors that exercised an influence on the job satisfaction of the dental hygienists and made an about 14.0% prediction of it. Out of those factors, the total length of career and monthly mean income had a statistically significant impact on that. Conclusions : The above-mentioned findings suggested that out of the seven job satisfaction components, they gave the lowest marks to satisfaction level with pay. As a result of making a multiple regression analysis, it's found that job satisfaction was under the influence of the total length of career and monthly mean income. Therefore there should be an improvement in the pay system in order to boost the job satisfaction of dental hygienists, and they should be paid properly in accordance with total length of career.

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Prediction of Risk Factors after Spine Surgery in Patients Aged >75 Years Using the Modified Frailty Index

  • Kim, Ji-Yoon;Park, In Sung;Kang, Dong-Ho;Lee, Young-Seok;Kim, Kyoung-Tae;Hong, Sung Jin
    • Journal of Korean Neurosurgical Society
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    • v.63 no.6
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    • pp.827-833
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    • 2020
  • Objective : Spine surgery is associated with higher morbidity and mortality rates in elderly patients. The modified Frailty Index (mFI) is an evaluation tool to determine the frailty of an individual and how preoperative status may impact postoperative survival and outcomes. This study aimed to determine the usefulness of mFI in predicting postoperative complications in patients aged ≥75 years undergoing surgery with instrumentation. Methods : We retrospectively reviewed the perioperative course of 137 patients who underwent thoracolumbar-instrumentation spine surgery between 2011 and 2016. The preoperative risk factors were the 11 variables of the mFI, as well as body mass index (kg/㎠), preoperative hemoglobin, platelet, albumin, creatinine, anesthesia time, operation time, estimated blood loss, and transfusion amount. The 60-day occurrences of complication rates were used for outcome assessment. Results : Major complications after spinal instrumentation surgery occurred in 34 of 138 patients (24.6%). The mean mFI score was 0.18±0.12. When we divided patients into a pre-frail group (mFI, 0.09-0.18; n=94) and a frail group (mFI ≥0.27; n=44), only the rate of sepsis was statistically higher in the frail group than in the pre-frail group. There were significantly more major complications in patients with low albumin levels or in patients with infection or who had experienced trauma. The mFI was a more useful predictor of postoperative complications than the American Society of Anesthesiologists physical status score. Conclusion : The mFI can successfully predict postoperative morbidity and mortality in patients aged ≥75 years undergoing spine surgery. The mFI improves perioperative risk stratification that provides important information to assist in the preoperative counselling of patients and their families.

Analysis and Prediction for Spatial Distribution of Functional Feeding Groups of Aquatic Insects in the Geum River (금강 수계 수서곤충 섭식기능군의 공간분포 분석 및 예측)

  • Kim, Ki-Dong;Park, Young-Jun;Nam, Sang-Ho
    • Journal of the Korean Association of Geographic Information Studies
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    • v.15 no.1
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    • pp.99-118
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    • 2012
  • The aim of this study is to define a correlation between spatial distribution characteristics of FFG(Functional Feeding Groups) of aquatic insects and related environmental factors in the Geum River based on the theory of RCC(River Continuum Concept). For that objective we had used SMRA(Stepwise Multiple Regression Analysis) method to analyze close relationship between the distribution of aquatic insects and the physical and chemical factors that may affect their inhabiting environment in the study area. And then, a probabilistic method named Frequency Ratio Model(FRM) and spatial analysis function of GIS were applied to produce a predictive distribution map of biota community considering their distribution characteristics according to the environmental factors as related variables. As a result of SMRA, the values of decision coefficient for factors of elevation, stream width, flow velocity, conductivity, temperature and percentage of sand showed higher than 0.5. Therefore these 6 environmental factors were considered as major factors that might affect the distribution characteristics of aquatic insects. Finally, we had calculated RMSE(Root Mean Square Error) between the predicted distribution map and prior survey database from other researches to verify the result of this study. The values of RMSE were calculated from 0.1892 to 0.4242 according to each FFG so we could find out a high reliability of this study. The results of this study might be used to develop a new estimation method for aquatic ecosystem with macro invertebrate community and also be used as preliminary data for conservation and restoration of stream habitats.

A Meta Analysis of the Effects of Road Safety Facilities on Accident Reduction: Focusing on Signalized Intersection (도로안전시설의 사고감소효과 메타분석 : 신호교차로를 대상으로)

  • CHOI, Ji Hye;LIM, Joon Beom;LEE, Soo Beom
    • Journal of Korean Society of Transportation
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    • v.34 no.4
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    • pp.291-303
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    • 2016
  • The number of traffic accidents at intersections has been increased over the past decade, and in 2014, accounted for 44% of the total traffic accidents. In addition, since most of road accident black spots include signalized intersections, the improvement of safety on signalized intersection is top priority for national road safety program in Korea. For the decision of most effective action plan for the safety of signalized intersection, this study conducted meta-analyses to assess the effects of various road safety facilities at signalized intersection on traffic accidents. We selected 19 articles regarding the prediction of traffic accidents at signalized intersection and calculated 34 individual effect sizes on 8 variables included in the articles. The results found that there was a statistically significant negative relationship between the occurrence of traffic accident and the presence of all of road safety facilities except an exclusive left turn bay. It shows that most of the road safety facilities could prevent traffic accidents, and intersection channelization has the most effective on the reduction of traffic accidents followed by left-turn acceleration lane, lightning, crosswalk, exclusive right-turn lane and median barrier.

Effects of feeding high-energy diet on growth performance, blood parameters, and carcass traits in Hanwoo steers

  • Kang, Dong Hun;Chung, Ki Yong;Park, Bo Hye;Kim, Ui Hyung;Jang, Sun Sik;Smith, Zachary K.;Kim, Jongkyoo
    • Animal Bioscience
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    • v.35 no.10
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    • pp.1545-1555
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    • 2022
  • Objective: Our study aimed to investigate the effects of a 2% increase in dietary total digestible nutrients (TDN) value during the growing (7 to 12 mo of age) and fattening (13 to 30 mo of age) period of Hanwoo steers. Methods: Two hundred and twenty Hanwoo steers were assigned to one of two treatments: i) a control group (basal TDN, BTDN, n = 111 steers, growing = 70.5%, early fattening = 71.0%, late fattening = 74.0%) or high TDN (HTDN, n = 109 steers, growing = 72.6%, early = 73.1%, late = 76.2%). Growth performance, carcass traits, blood parameters, and gene expression of longissimus dorsi (LD) (7, 18, and 30 mo) were quantified. Results: Steers on the BTDN diets had increased (p≤0.02) DMI throughout the feeding trial compared to HTDN, but gain did not differ appreciably. A greater proportion of cattle in HTDN received Korean quality grade 1 (82%) or greater compared to BTDN (77%), while HTDN had a greater yield grade (29%) than BTDN (20%). Redness (a*) of LD muscle was improved (p = 0.021) in steers fed HTDN. Feeding the HTDN diet did not alter blood parameters. Steers fed HTDN diet increased (p = 0.015) the proportion of stearic acid and tended to alter linoleic acid. Overall, saturated, unsaturated, monounsaturated, and polyunsaturated fatty acids of LD muscle were not impacted by the HTDN treatment. A treatment by age interaction was noted for mRNA expression of myosin heavy chain (MHC) IIA, IIX, and stearoyl CoA desaturase (SCD) (p≤0.026). No treatment effect was detected on gene expression from LD muscle biopsies at 7, 18, and 30 mo of age; however, an age effect was detected for all variables measured (p≤0.001). Conclusion: Our results indicated that feeding HTDN diet could improve overall quality grade while minimum effects were noted in gene expression, blood parameters, and growing performance. Cattle performance prediction in the feedlot is a critical decision-making tool for optimal planning of cattle fattening and these data provide both benchmark physiological parameters and growth performance measures for Hanwoo cattle feeding enterprises.

Influence on Predicted Performance of Jointed Concrete Pavement with Variations in Axle Load Spectra (축하중 분포 변화가 콘크리트 포장의 공용성 예측결과에 미치는 영향 연구)

  • Lee, Kyungbae;Kwon, Soonmin;Lee, Jaehoon;Sohn, Duecksu
    • International Journal of Highway Engineering
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    • v.16 no.1
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    • pp.11-19
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    • 2014
  • PURPOSES : The purpose of this article is to investigate the predicted life of jointed concrete pavement (JCP) with two variables effecting on axle load spectra (ALS). The first variable is different data acquisition methods whether using high-speed weigh-in-motion (HS-WIM) or not and the other one is spectra distribution due to overweight enforcement on main-lane of expressway using HS-WIM. METHODS : Three sets of ALS had been collected i) ALS provided by Korea Pavement Research Program (KPRP), which had been obtained without using HS-WIM ii) ALS collected by HS-WIM before the enforcement at Kimcheon and Seonsan site iii) ALS collected after the enforcement at the same sites. And all ALS had been classified into twelve vehicle classes and four axle types to compare each other. Among the vehicle classes, class 6, 7, 10 and 12 were selected as the major target for comparing each ALS because these were considered as the primary trucks with a high rate of overweight loading. In order to analyze the performance of JCP based on pavement life, fatigue crack and International Roughness Index (IRI) were predicted using road pavement design program developed by KPRP and each ALS with same annual average daily traffic (AADT) was applied to design slab thickness. RESULTS : Comparison ALS of KPRP with those of HS-WIM shows that the ALS of KPRP has a low percentage of heavy spectra such as 6~9 tonnes for single axle, 18~21 tonnes for tandem axle and 27~30 tonnes for tridem axle than other two ALS of HS-WIM in most vehicle classes and axle types. It means that ALS of KPRP was underestimated. And after the enforcement, percentage of heavy spectra close to 10 tonnes per an axle are lowered than before the enforcement by the effect of overweight enforcement because the spectra are related to overweight regulation. Prediction results of pavement life for each ALS present that the ALS of HS-WIM collected before the enforcement makes the pavement life short more than others. On the other hand, the ALS of KPRP causes the longest life under same thickness of slab. Thus, it is possible that actual performance life of JCP under the traffic like ALS of HS-WIM could be short than predicted life if the pavement was designed based on ALS provided by KPRP. CONCLUSIONS : It is necessary to choose more reliable and practical ALS when designing JCP because ALS can be fairly affected by acquisition methods. In addition, it is important to extend performance life of the pavement in service by controlling traffic load such as overweight enforcement.

Study on Anomaly Detection Method of Improper Foods using Import Food Big data (수입식품 빅데이터를 이용한 부적합식품 탐지 시스템에 관한 연구)

  • Cho, Sanggoo;Choi, Gyunghyun
    • The Journal of Bigdata
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    • v.3 no.2
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    • pp.19-33
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    • 2018
  • Owing to the increase of FTA, food trade, and versatile preferences of consumers, food import has increased at tremendous rate every year. While the inspection check of imported food accounts for about 20% of the total food import, the budget and manpower necessary for the government's import inspection control is reaching its limit. The sudden import food accidents can cause enormous social and economic losses. Therefore, predictive system to forecast the compliance of food import with its preemptive measures will greatly improve the efficiency and effectiveness of import safety control management. There has already been a huge data accumulated from the past. The processed foods account for 75% of the total food import in the import food sector. The analysis of big data and the application of analytical techniques are also used to extract meaningful information from a large amount of data. Unfortunately, not many studies have been done regarding analyzing the import food and its implication with understanding the big data of food import. In this context, this study applied a variety of classification algorithms in the field of machine learning and suggested a data preprocessing method through the generation of new derivative variables to improve the accuracy of the model. In addition, the present study compared the performance of the predictive classification algorithms with the general base classifier. The Gaussian Naïve Bayes prediction model among various base classifiers showed the best performance to detect and predict the nonconformity of imported food. In the future, it is expected that the application of the abnormality detection model using the Gaussian Naïve Bayes. The predictive model will reduce the burdens of the inspection of import food and increase the non-conformity rate, which will have a great effect on the efficiency of the food import safety control and the speed of import customs clearance.