• Title/Summary/Keyword: Prediction mole fraction of DNA

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Prediction of Composition Ratio of DNA Solution from Measurement Data with White Noise Using Neural Network (잡음이 포함된 측정 자료에 대한 신경망의 DNA 용액 조성비 예측)

  • Gyeonghee Kang;Minji Kim;Hyomin Lee
    • Korean Chemical Engineering Research
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    • v.62 no.1
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    • pp.118-124
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    • 2024
  • A neural network is utilized for preprocessing of de-noizing in electrocardiogram signals, retinal images, seismic waves, etc. However, the de-noizing process could provoke increase of computational time and distortion of the original signals. In this study, we investigated a neural network architecture to analyze measurement data without additional de-noizing process. From the dynamical behaviors of DNA in aqueous solution, our neural network model aimed to predict the mole fraction of each DNA in the solution. By adding white noise to the dynamics data of DNA artificially, we investigated the effect of the noise to neural network's predictions. As a result, our model was able to predict the DNA mole fraction with an error of O(0.01) when signal-to-noise ratio was O(1). This work can be applied as a efficient artificial intelligence methodology for analyzing DNA related to genetic disease or cancer cells which would be sensitive to background measuring noise.