• Title/Summary/Keyword: Pre-treated

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Effect of Kamicheonggan-tang on Pre-hepatocarcinogenesis Induced by N-nitrosomorpholine (가미청간탕이 N-nitrosomorpholine으로 유도된 전암성 간병변에 미치는 영향)

  • Kim Dong Hee;Choi Jeung Mok;Jo Dong il
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.16 no.4
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    • pp.734-744
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    • 2002
  • The purpose of this study was to evaluate the protective effect of Kamicheonggan-tang(KCGT) on pre-hepatocarcinogenesis induced by N-nitrosomorpholine. The studied using blood chemistry, lipidperoxidation, antioxidant, immunohistochemistry and morphological change. The results were obtained as follows. In the pre-hepatocarcinogenesis induced by NMP, serum AST, ALT, ALP and total bilirubin were not changed in NMP and NK treated group after 1 st week, but desreased in NK treated group after 4th week as compared with NMP treated 4th week group. The content of GSH was similary to in NK treated groups as compares with data of normal group. The content of MDA was increased in NK treated group after 1st and 4th week, and more increased in the NMP treated group than those of their NK treated group. The immunohistochemically, stain of GST-p, positive lesions of KCGT were significantly decreased than those of NMP treated group. The histopathologically, fat changes, nucleotic changes, oval cell and inflammatory cells in periportal were observed in NMP treated fater 4th week, but those were significantly decreased from 4th week in the NK treated group. And the enlarged nucleus was not changed in KCGT treated group, but increased in NMP treated group after 1st and 4th week. The ultrastructurally, nucleotic changes, glycogen degeneration, lipid droplet and rER fragmentation were observed in NMP treated group after 4th week, but those changes were significantly decreased from 4th week in the NK treated group. These results suggested that KCGT extracts has protective effect on prehepatocarcinogenesis by NMP, might be usefully applied for clinical treatment of hapatic disease and also it was necessary to do more studies about its mechanisms.

Hydroformability and mechanical properties of A16061 tubes on different extrusion type (알루미늄 6061 압출재의 제조공정에 따른 온간액압성형성과 기계적 특성 연구)

  • Yi, H.K.;Jang, J.H.;Kwon, S.O.;Lee, Y.S.;Moon, Y.H.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2007.05a
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    • pp.254-257
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    • 2007
  • In this study, hydroformability and mechanical properties of pre- and post- heat treated Al6061 tubes at different extrusion type were investigated. For the investigation, as-extruded, full annealed and T6-treated Al 6061 tubes at different extrusion type were prepared. To evaluate the hydroformability, uni-axial tensile test and free bulge test were performed at room temperature and $200^{\circ}C$. Also mechanical properties of hydroformed part at various pre- and post-heat treatments were estimated by tensile test. And the tensile test specimens were obtained from hexagonal prototype hydroformed tube at $200^{\circ}C$. As for the heat treatment, hydroformability of full annealed tube is 25% higher than that of extruded tube. The tensile strength and elongation were more than 330MPa and 12%, respectively, when hydroformed part was post-T6 treated after hydroforming of pre- full annealed tube. However, hydroformed part using T6 pre treated tube represents high strength and low elongation, 8%. Therefore, the T6 treatment after hydroforming for as-extruded tube is cost-effective. Hydroformability of Al6061 tube showed similar value for both extrusion types. But flow stress of seam tube showed $20{\sim}50MPa$ lower value.

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Protozoa as an Indicator of Activated In Sludge Plant Effluent Quality (원생동물을 이용한 하수처리장의 수질 예측)

  • 이찬형;문경숙
    • Microbiology and Biotechnology Letters
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    • v.28 no.6
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    • pp.361-366
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    • 2000
  • Genera and number of protozoa were investigated in the conventional activated sludge pilot plant used for the treatment of municipal sewage and pre-treated night soil-containing sewage. In both case, the predominant protozoa was ciliates and among them Vorticella was the most common. In the pilot plant where pre-treated night soil was mixed with municipal sewage, genera of free-swimming ciliates, flagellates and amoeba was higher than in those withour night soil. Correlation analysis on the quality of effluent and protozoa indicates that municipal sewage has positive correlation with protozoa. However in the pilot plan 샐 sewage contatinin pre-treated night coil soil more samples show negative correlation. Followed equations were derived by the regression analysis of BOD in both the pilot plants. In case of pilot plant A of municipal sewage, the analysis B of munici-pal and pre-treated night soil-containing sewage, the analysis of BOD was $6.731$\times$10_{-2}$ $\times$Bodo+0.306(Adjusted $R^2$=0.864). At low temperature, number of protozoa was decreased to 35% and among therm, Aspidisca was the most common genus. Therefore, protozoa can be used as indicator of quality of the effluent in sewage treatment plants.

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Potassium loading effects for activated carbon fiber pre-treated with phosphoric acid (인산을 전처리한 활성탄소섬유에 칼륨 처리효과)

  • Oh, Won-Chun;Bae, Jang-Soon
    • Analytical Science and Technology
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    • v.18 no.4
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    • pp.355-361
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    • 2005
  • The objective of this paper is to compare the surface features of two kinds of activated caron fiber (ACF) treated with potassium and the variation of their properties by phosphoric acid pre-treatment. X-ray diffraction (XRD) patterns indicate that activated carbon fiber containing potassium species show better performance for metal and metal salts by pre-treatment with phosphoric acid. In order to present the causes of the differences in surface properties and specific surface area after the samples were treated with phosphoric acid, pore structure and surface morphology were investigated by adsorption analysis and SEM. For the chemical composition microanalysis for potassium leading of the activated carbon fibers pre-treated with phosphoric acid, samples were analyzed by EDX. Finally, the type and quality of oxygen groups were determined from the method proposed by Boehm.

Effect of process type and heat treatment conditions on warm hydroformability (온간액압성형특성에 미치는 압출제조공정과 열처리 조건의 영향)

  • Yi, H.K.;Kwon, S.O.;Park, H.K.;Yim, H.S.;Lee, Y.S.;Moon, Y.H.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2007.10a
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    • pp.132-135
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    • 2007
  • In this study, hydroformability and mechanical properties of pre- and post- heat treated Al6061 tubes at different extrusion type were investigated. For the investigation, as-extruded, full annealed and T6-treated Al6061 tubes at different extrusion type were prepared. To evaluate the hydroformability, uni-axial tensile test and free bulge test were performed at room temperature and $250^{\circ}C$. Also mechanical properties of hydroformed part at various pre- and post-heat treatments were estimated by tensile test. And the tensile test specimens were obtained from hexagonal prototype hydroformed tube at $250^{\circ}C$. As for the heat treatment, hydroformability of full annealed tube is 25% higher than that of extruded tube. The tensile strength and elongation were more than 330MPa and 12%, respectively, when hydroformed part was post-T6 treated after hydroforming of pre- full annealed tube. However, hydroformed part using T6 pre treated tube represents high strength and low elongation, 8%. Therefore, the T6 treatment after hydroforming for as-extruded tube is cost-effective. Hydroformability of Al6061 tube showed similar value for both extrusion types. But flow stress of seam tube showed $20{\sim}50MPa$ lower value.

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The Inhibitory Effect of Chlorophyllin is Influenced by Different Promotion Stages in DMBA-TPA-induced Mouse Skin Carcinogenesis

  • Kim, Jin;Yook, Jong-In;Park, Kwang-Kyun;Lee, Eun-Ha;Jung, So-Young;Joon, Yin-Liu;Kyung, Chul-Hong;Kim, Ju;Chung, Won-Yoon
    • Environmental Mutagens and Carcinogens
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    • v.19 no.1
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    • pp.46-55
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    • 1999
  • To develop a chemopreventive strategy based on the different stages of premalignant lesions, we hypothesized that the inhibitory effect of chemopreventive agents is influenced by different promotion stages during carcinogenesis. DMBA-TPA-induced skin carcinogenesis was used with ICR mice and chlorophyllin (CHL) was applied as a chemopreventive agent. In vitro assay was performed with Salmonella typhi. TA100 to observe any anti-mutagenic activity of CHL against DMBA. Pre-initiation and pre-promotion effects of CHL were observed by CHL treatment before initiation and before promotion. To evaluate the inhibitory effect at different promotion stages, each group was divided into three subgroups after TPA promotion for 6, 18 and 24 weeks, respectively ; the first subgroup was immediately sacrificed after termination of TPA, the second subgroup was treated with CHL, and the third subgroup was sacrificed 8 weeks after termination of TPA without CHL treatment. The degrees of epithelial dysplasia, papilloma formation, and invasive carcinoma were observed histologically, and GST-Pi expression was observed immunohistochemically. ODC mRNA level was analyzed by reverse transcriptase-polymerase chain reaction. Results showed : CHL dose-dependently inhibited the mutation of Salmonella typhi. TA100; the incidence of epithelial dysplasia and papilloma formation was lower in pre-initiation and pre-promotion CHL-treated mice than DMBA-TPA-treated mice; no invasive carcinoma developed in pre-initiation CHL-treated groups, while 67% of DMBA-TPA treated mice had carcinomas; GST-Pi expression decreased when CHL was treated before initiation and before promotion; and when CHL was treated after termination of TPA application at 18 and 24- week-TPA promotion stages, respectively, the incidence of epithelial dysplasia and papilloma was markedly reduced compared to non-treated groups. When comparing the incidence of epithelial dysplasia and papilloma between the immediately-sacrificed subgroup and the non-treated group with a waiting period, we speculated that the 18-week-TPA promotion stage might belong to the promoter-independent progression stage. At the 18-week-TPA promotion stage, the level of ODC mRNA in the CHL-treated group was clearly reduced to the level of normal tissue. Taking these results together, CHL showed both anti-initiation and anti-promotion effects, while the inhibitory effect of CHL was prominent in the 18-week-TPA promotion stage. However, CHL seems to be incapable of completely blocking the progression in the 24-week-TPA promotion stage.

A Study on the Mechanical Properties of Shrink-Resistant Wool Fabric Treated with Enzyme (효소에 의한 방축가공 양모직물의 물성 변화에 관한 연구)

  • 박미라;김환철;박병기
    • Textile Coloration and Finishing
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    • v.13 no.3
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    • pp.155-164
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    • 2001
  • Textile wet-processing industry usually five rise to environmental pollution problems caused by using chemical substance. The objective of this study is to apply enzymes for wool and reduce the environmental problems. Three commercial protein degradation enzymes and a cellulose degradation enzyme as a reference were treated to prevent the shrinkage of wool fabric on laundering. Shrink resistant effects used change with the kinds of enzyme, the amount of enzyme, assistant chemicals, and the pre-treatment condition of wool fabric. When pre-treated with corona before enzyme treatment under ultrasonic condition, the weight loss was increased and strength was decreased and elongation was increased. Both corona pre-treatment and the addition of $Na_2SO_4$ also decreased shrinkage of wool fabrics on laundering. The existence of assistant chemicals increased alkali solubility of wool fabrics.

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Utility Estimation of Pre-filtration on the Membrane Water Treatment Process (막여과 정수처리공정에서 전여과공정의 효용성 평가)

  • Park, Min Koo;Choi, Sang il
    • Journal of Korean Society of Water and Wastewater
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    • v.22 no.4
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    • pp.445-448
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    • 2008
  • The application of the membrane filtration process has been increased for the drinking water treatment system because of excellent quality of treated water compared with the sand filtration process. The selection of suitable pre-treatment processes and optimum flux according to the characteristics of raw water are important factors for the design of membrane processes. In this study, the most efficient pre-treatment processes for drinking water was selected by investigating the effects of pre-treatment processes on the operational stability of the membrane filtration process. Both lab-scale and pilot-scale experiments were conducted. In the lab-scale test, the effect of pre-treatment processes on the stability of the membrane filtration process was investigated indirectly by comparing the performance of membrane flux for raw water, pre-treated water, and membrane permeated water. In the pilot-scale test, the usefulness of prefiltration processes was assessed by comparing the performance of single membrane process and hybrid coagulation-membrane process. The results indicated that the coagulation process contributed to the stabilization of trans-membrane pressure (TMP) by removing contaminants on membranes, though the pre-filtration process had little effect on the TMP.

The effect of Several Pulp properties and freeness treated with different sized cellulase (섬유소 분해효소의 분자량에 따른 조합처리가 종이의 강도 변화 및 표면 변화에 미치는 영향)

  • 김병헌
    • Journal of the Korean Graphic Arts Communication Society
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    • v.19 no.1
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    • pp.75-85
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    • 2001
  • This study confirmed different results according to the molecular weight and pore properties of treated pulp. In this study the pre-treated enzyme material was increasing the beating speed compared with non-treated one. And it was observed that the change of freeness according to the combination ratio depended upon the pores size of pulp and that fibers became flexible owing to the physical deformation of fibers themselves through pre-treated enzyme increasing the flexibility of fibers to increase the contact area of fiber and thus resulting in the increase of specific surface area, the increase of fiber bonding strength and the increase of beating speed.

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