• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.5635-5641
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• 2015

Background: Cirrhosis is regarded as a possible end stage of many liver diseases, including viral infection. It occurs when healthy liver tissue becomes damaged and is replaced by scar tissue and finally may lead to hepatocellular carcinoma. Interferons (IFNs)are two general categories, type I and II. Type I includes one beta interferon and over 20 different alpha interferons. Alpha interferons are very similar in how they work, interacting with other proteins on cells like receptors. The main objective of this study was to compare Mx gene productivity post different cell line treatment with imported and Egyptian biosimilar locally produced IFNs, as well as the efficacy of those tested IFNs. Also, an assessment was made of sensitivity of different cell lines as alternatives to that recommended for evaluation of antiviral activity. Materials and Methods: Different cell lines (Vero, MDBK and Wish) were employed to evaluate cytotoxicity using the MTT assay. Antiviral activity was evaluated compared with standard IFN against VSV, Indiana strain -156, on tested rh-IFNs (imported; innovated and Egyptian biosimilar locally produced IFNs) in the pre-treated cell lines previously mentioned. The virus was propagated in the Wish cell line as recommended. Finally we estimated up-regulation of the Mx gene as a biomarker. Results: Data recorded revealed that test IFNs were safe in test cell lines. Viability was around 100%. Locally tested interferon did not realize the international potency limits, while the imported one was accepted compared with the standard IFN. These results were the same either using infectivity titer reduction assay or crystal violet staining of residual non- infected cells. Mx protein production was cell type related and confirmed by the detected Mx gene expressed in imported and locally produced IFN pre-treated cell lines. The expression of the gene was arranged in the order of Vero> wish > MDBK for the imported IFN, while for the Egyptian biosimillar locally produced one it was MDBK> Vero> wish. With regard to the antiviral activity there was a significant difference of imported IFN potency compared with the locally produced IFN (P<0.05), the IFN potential (antiviral activity) was not cell line related and showed non-significant difference for each separate product. Conclusions: Vero cells can be used as an alternative cell line for evaluation of IFN potency in case of unavailable USP recommended cell lines. Alternative potency evaluation assay could be used and proved significant difference in IFN potency in case of local and imported agents. Evaluation of antiviral activity could be used in parallel to viral infectivity reduction assay for better accuracy. Mx gene can be used as a marker for IFN potential.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2006년 학술대회 논문집 정보 및 제어부문
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• pp.563-566
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• 2006

In this paper, we studied about AGVs modeling and material handling automation simulation using a virtual AGV. The proposed virtual AGV model that operates independently each other is based on a real AGV. Continuous straight-line and workstation model using vector drawing method that could easily, rapidly work system modeling are suggested. Centralized traffic control, which could collision avoidance in intersection and should not stop AGV as possible, and algorithm for detour routing which performs when another AGV is working in pre-routed path are proposed. The traffic control and the algorithm have been proved efficiently by simulation.

• 대한임베디드공학회논문지
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• 제7권5호
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• pp.247-253
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• 2012

This paper presents sensor network based autonomous vehicle system using a proposed image processing algorithm. The proposed image processing algorithm consists of pre-processing and five-stage image processing: coordinate calculation, driving area decision, line segment calculation, steeling decision, and acceleration decision. We evaluate the performance of the proposed algorithm on both straight road and curved road. Experimental results indicate that the proposed algorithm works well for autonomous vehicles. However, control accuracy of the proposed algorithm decreases as speed is increasing.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1998년도 추계학술대회 논문집 학회본부 B
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• pp.651-653
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• 1998

This thesis propose the prefilter type control strategies using modified chaotic neural networks #or the trajectory control of robotic manipulator. Since the structure of chaotic neural networks and neurons, chaotic neural networks can show the robust characteristics for controlling highly nonlinear dynamics like robotic manipulators. For its application, the trajectory controller of the three-axis PUMA robot is designed by CNN. The CNN controller acts as the compensator of the PD controller. Simulation results show that learning error decrease drastically via on- line learning and the performance is excellent. The CNN controller have much better controllability and shorter calculation time compared to the RNN controller. Another advantage of the proposed controller could be attached to conventional robot controller without hardware changes.

• 제어로봇시스템학회논문지
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• 제15권5호
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• pp.465-472
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• 2009

This paper proposes a multimodal information transformation system that converts the image information to the voice information to provide the sight impaired people with walking area and obstacles, which are extracted by an acquired image from a single CCD camera. Using a chain-code line detection algorithm, the walking area is found from the vanishing point and boundary of a sidewalk on the edge image. And obstacles are detected by Gabor filter of extracting vertical lines on the walking area. The proposed system expresses the voice information of pre-defined sentences, consisting of template words which mean walking area and obstacles. The multi-modal information transformation system serves the useful voice information to the sight impaired that intend to reach their destination. The experiments of the proposed algorithm has been implemented on the indoor and outdoor environments, and verified its superiority to exactly provide walking parameters sentences.

• 제어로봇시스템학회논문지
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• 제15권5호
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• pp.548-554
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• 2009

We propose an automatic inspection system for hologram with multiple patterns. The system hardware consists of illuminations, camera, and vision processor. Multiple illuminations using LEDs are arranged in different directions to acquire each image of patterns. The system software consists of pre-processing, pattern generation, and pattern matching. The acquired images of input hologram are compared with their reference patterns by developed matching algorithm. To compensate for the positioning error of input hologram, reference patterns of hologram for different position should be generated in on-line. We apply a frequency transformation based CGH(computer-generated hologram) method to generate reference images. For the fast pattern matching, we also apply the matching method in the frequency domain. Experimental results for hologram of Korean currency are then presented to verify the usefulness of proposed system.

• 전자공학회논문지C
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• 제36C권6호
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• pp.52-62
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• 1999

본 논문에서는 가상 환경에서 움직이는 인체 Avatar의 움직임을 인간의 가장 자연스러운 동작의 하나인 손 제스처를 이용하여 실시간으로 제어하는 인식 시스템의 구현에 관하여 상술한다. 동적 손 제스처는 컴퓨터와 제스처를 사용하는 사람과의 상호 연결 수단이다.가상공간 상에서의 자연스러운 움직임을 표현하기 위해 32개의 자유도(DOF)를 가진 인체 아바타를 구성하였으며, 정지, 전후좌우로 한 걸음 이동, 걷기, 달리기, 좌우로 회전, 뒤로 돌기, 물건 잡기의 동작 모드를 정의하여 가상공간 상의 인체 아바타는 미리 설정된 손 제스처에 따라 실시간에 따라 실시간으로 3차원공간상에서 움직일 수 있다. 실시간의 인체 아바타 이동에는 역 기구학과 기구학을 혼용하여 적용하였으며, 사이버 터치를 착용한 사용자의 손 제스처 인식에는 인공 신경망 이론과 퍼지 이론을 도입하여 실시간 인식이 가능하였다.

• 한국컴퓨터정보학회논문지
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• 제22권2호
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• pp.133-139
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• 2017

Today, the activities of individuals and corporations are dependent not only on digital technology but also on the future of society, which is referred to as the fourth industrial revolution. Since the traces that arise from the crimes that occur in the digital society are also inevitably developed into a society that should be found in the digital, the judicial dependence of judging by the digital evidence is inevitably increased in the criminal procedure. On the other hand, considering the fact that many users are using virtual shared computing resources of service providers considering the fact that they are being converted into a cloud computing environment system, searching for evidence in cloud computing resources is not related to crime. The possibility of infringing on the basic rights of the criminal procedure is increased, so that the ability of evidence of digital data which can be used in the criminal procedure is limited. Therefore, considering these two aspects of digital evidence, this point should be fully taken into account in judging the evidence ability in the post-seizure warrant issuance and execution stage as well as the pre-emptive control. There is a view that dictionary control is useless, but it needs to be done with lenient control in order to materialize post-modern control through judging ability of evidence. In other words, more efforts are needed than ever before, including legislation to ensure proper criminal procedures in line with the digital age.

• 한국해안·해양공학회논문집
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• 제21권5호
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• pp.380-390
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• 2009

본 연구는 우리나라 남동 해안에 위치한 매립지(안정국가산업단지, 명지주거단지 및 녹산국가산업단지)에서 해안빈지 면적 산출을 위하여 항공사진으로부터 매립이전의 해안선을 조사하는 연구의 일환으로 수행되었다. 매립 이전 해안선의 적합성을 평가하고자 해안선변화자료를 구축하였다. 2차적인 지상기준점으로 오래된 항공사진의 항공삼각측량을 수행하였다. 해안선은 약최고고조위(AHHWL)에 해당하는 해안선과 wet/dry 흔적에 의한 고조선(HWL)을 도화하였다. 인공적인 해안에서 두 종류의 해안선은 잘 일치하였다. 항공사진 축척, 품질, 지상기준점 선정, 해안선 인식 등 세부적인 차이로 인하여 해안선변화자료는 다양한 오차수준으로 구성되었다. 정성적인 해안선변화 추이를 살펴보는 수준에서 매립 이전 해안선의 적합성은 만족할 만하였다. 본 연구지역에서 매립 이전의 해안선 변화는 대부분이 연안개발로 발생하였다. 항공사진과 연계하여 해안선의 속성을 파악함으로써 해안선 변화에 대한 이해가 가능하였다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2002년도 하계학술대회 논문집 D
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• pp.2353-2356
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• 2002

The increase of vehicles stagnations leads to the increasing attention to the way customers pay and a large number of projects on electronic cash system. Tranport system is comprised of a number of advanced technologies, including information processing, communications, control, and electronics. Recently many research on a system which provides contact in order to protect driver's vehicle passage have been carried out. And some potential problems from that system are being reviewed by electronic cash system. In this papers, we suggest RF protocol developing technology using the concept of electronic cash. ATM electronic cash developing is consist of component of pre-developed coin throw, integration of component using its, and production of more requirement-satisfactory ITS solution. Result increase 15$\sim$40% pre-type vehicles stagnations. Especially, we expect this proposed concept would be well adapted to our national environments.