• Title/Summary/Keyword: Pre-conditioning

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Effects of additional electrical stimulation and pre-rigor conditioning temperature on the ageing potential of hot-boned bovine muscles

  • Balan, Prabhu;Farouk, Mustafa M.;Staincliffe, Maryann;Stuart, Adam D;Kemp, Robert;Craigie, Cameron
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.10
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    • pp.1642-1655
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    • 2020
  • Objective: The aim of this study is to characterize the impact of additional electrical stimulation (AES) and various pre-rigor holding temperatures (for 3 h) on the ageing-potential of hot boned bovine M. longissimus lumborum (LL). Methods: Paired LL loins from 12 bulls were hot-boned within 40 min of slaughter, immediate AES applied and subjected to various holding temperatures (5℃, 15℃, 25℃, and 35℃) for 3 h. Results: AES did not accelerate the rate of rigor attainment, but the 3 h pre-rigor holding temperature did. Shear force values decreased as the pre-rigor holding temperatures increased. AES and holding for 3 h (at 25℃) resulted in higher water-holding capacity. Conclusion: Data confirmed that AES did not influence the various meat quality parameters in the present study, but pre-rigor holding temperature (25℃) alone or in combination with AES resulted in superior meat quality.

A Study of the Development of a Modular, Lightweight Steel Ceiling System (유닛형 경량철골 천정시스템 개발에 관한 연구)

  • Kim, Hyeyeon;Bae, Sanghwan
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.29 no.5
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    • pp.269-277
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    • 2017
  • This study consists of an analysis of pre-existing ceiling construction systems as well as the development of a replacement unitary, lightweight steel ceiling system and related legal standards. Based on the material conditions and progression of the study, appropriate components were chosen and details were modified by mock-up test. A final study model was evaluated for performance and adaptability based on four parameters (indoor environment, constructability, budget economy, and aesthetics) and compared to the pre-existing ceiling system. As a result of the initial study, a lightweight steel design was created consisting of a reinforced structure with modular bars and entry holes for components. This system was hung directly on the suspension structure. The new design increased lighting and acoustic performance adapted to an indoor environment. Moreover, the speed of construction was increased by approximately 30%, the cost was decreased by approximately 20%, and ceiling aesthetics were improved.

Study on the Flow Characteristics of R-22, R-l34a in Small Diameter Tubes (R-22 및 R-134a의 세관 내 유동 특성에 관한 연구)

  • 홍진우;정재천;장승환;권옥배;오후규
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.14 no.9
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    • pp.756-765
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    • 2002
  • Experimental work was performed on the flow characteristics of R-22 and R-l34a in small diameter tubes. The experimental apparatus was made up of liquid pump, pre-heater, sight-glass, condenser and measurement instruments. The sight-glass for flow pattern observations was located at the outlet of the pre-heater. The experiment was carried out to show the flow characteristics of R-22 and R-l34a. Data were taken with test conditions in the following ranges; the mass flux was ranged from 100 to 1,000 kg/$m^2s$, the saturation temperature was $30^{\circ}C$ and the vapor quality was ranged from 0.1 to 0.9. The main results were summarized as follows; In the flow patterns during evaporation, the annular flow in a 2 mm inner diameter tube occurred at a relatively lower quality and mass velocity, compared to the flow in a 8mm inner diameter tube. The evaporation flow in small diameter tubes has been shown major deviations with the Mandhane, Taitel-Dukler's and Wambs-ganss' flow pattern maps but it was similar to the Dobson's flow pattern map.

Development of a Pre/Post Processor Program for the Analysis of the Passenger Flow based on Discrete Element Method(DEM) (DEM에 기초한 여객유동 해석을 위한 전/후처리 프로그램 개발)

  • Kim, Chi-Gyeom;Won, Chan-Shik;Hur, Nahm-Keon;Nam, Seong-Won
    • Proceedings of the SAREK Conference
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    • 2008.11a
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    • pp.475-480
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    • 2008
  • A pre/post processor program based GUI(Graphic User Interface) by using the MFC and OpenGL library in the Windows OS have been developed for the analysis of the passenger flow. Using this program, users are able to generate and modify the meshes of multi-storied subway station, set all the parameters for the solver, and obtain the results of the simulation such as transient passenger motions and passenger streak lines in 3-dimensional graphic view.

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Conditioning-induced cardioprotection: Aging as a confounding factor

  • Randhawa, Puneet Kaur;Bali, Anjana;Virdi, Jasleen Kaur;Jaggi, Amteshwar Singh
    • The Korean Journal of Physiology and Pharmacology
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    • v.22 no.5
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    • pp.467-479
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    • 2018
  • The aging process induces a plethora of changes in the body including alterations in hormonal regulation and metabolism in various organs including the heart. Aging is associated with marked increase in the vulnerability of the heart to ischemia-reperfusion injury. Furthermore, it significantly hampers the development of adaptive response to various forms of conditioning stimuli (pre/post/remote conditioning). Aging significantly impairs the activation of signaling pathways that mediate preconditioning-induced cardioprotection. It possibly impairs the uptake and release of adenosine, decreases the number of adenosine transporter sites and down-regulates the transcription of adenosine receptors in the myocardium to attenuate adenosine-mediated cardioprotection. Furthermore, aging decreases the expression of peroxisome proliferator-activated receptor gamma co-activator 1-alpha ($PGC-1{\alpha}$) and subsequent transcription of catalase enzyme which subsequently increases the oxidative stress and decreases the responsiveness to preconditioning stimuli in the senescent diabetic hearts. In addition, in the aged rat hearts, the conditioning stimulus fails to phosphorylate Akt kinase that is required for mediating cardioprotective signaling in the heart. Moreover, aging increases the concentration of $Na^+$ and $K^+$, connexin expression and caveolin abundance in the myocardium and increases the susceptibility to ischemia-reperfusion injury. In addition, aging also reduces the responsiveness to conditioning stimuli possibly due to reduced kinase signaling and reduced STAT-3 phosphorylation. However, aging is associated with an increase in MKP-1 phosphorylation, which dephosphorylates (deactivates) mitogen activated protein kinase that is involved in cardioprotective signaling. The present review describes aging as one of the major confounding factors in attenuating remote ischemic preconditioning-induced cardioprotection along with the possible mechanisms.

Study of Pre-ventilation Effects on the Cabin Thermal Load (주차환기 시스템이 차 실내 열부하에 미치는 영향에 관한 연구)

  • Lee, Daewoong
    • Transactions of the Korean Society of Automotive Engineers
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    • v.22 no.5
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    • pp.84-90
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    • 2014
  • The aim of this paper is to investigate the application of solar energy in reducing cabin thermal load. When a vehicle is parked under the sun in summer, the interior temperature can reach up to $70^{\circ}C$ depending on the solar intensity. Solar power, one of the green energies, is used in automobile air conditioning systems, in order to operate the blower. The power supply of a blower's voltage has been used in a solar sunroof experiment. At the climate wind tunnel, cabin temperature changes were conducted with various operating modes of an air handling system and the preventilation parking conditions of several vehicles, outdoors, was also examined. The test results of the solar sunroof, 39.3W power and 14.1% efficiency were obtained. The thermal load behavior was analysed with the air handling system operating mode differently according to the cabin temperature. By simply operating the blower, average cabin temperature decreased between $5^{\circ}C{\sim}10^{\circ}C$ in those vehicles parked outdoors in summer. This reveals that cabin thermal comfort can be improved without consuming the vehicle's extra energy, and that the performance of the air-conditioning system is better than those currently found in vehicles. Moreover, fuel economy will be increased as a result of the reduction in the use of the air-conditioning system, and many other human advantages will be gained. Such advantages include minimized VOCs and a healthy cabin environment.

Angelica gigas Nakai 현탁세포 배양의 동결보존 연구

  • Jo, Ji-Suk;Lee, Song-Jae;Jeon, Su-Hwan;Kim, Ik-Hwan;Kim, Dong-Il
    • 한국생물공학회:학술대회논문집
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    • 2000.04a
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    • pp.321-324
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    • 2000
  • Cell culture of Angelica gigas Nakai producing decursin and decursinol angelate as secondary metabolites were preserved in liquid nitrogen after pre-freezing in deep $freezer(-70^{\circ}C)$. The development of optimal procedure for cryopreservation was investigated by using cryoprotectant and pre-treatment before cooling. 0.7 M sucrose was found be the optimum osmotic pre-conditioning culture medium compared to mannitol, sorbitol and NaCl with the same osmotic pressure. In pre-culture medium, cells in exponential phase, supported the best growth after cryopreservation. Effective cryoprotectant was proved to be a mixture of sucrose, glycerol, DMSO. Higher concentration of cryoprotectant was better for cell viability. The highest relative cell viability established after the development of optimal procedure was 65%.

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Heat Transfer and Pressure Drop Characteristics of Supercritical $CO_2$ in a Helically Coiled Tube (초임계 $CO_2$의 헬리컬 코일관 내 열선단과 압력강하 특성)

  • Yu, Tae-Guen;Kim, Dae-Hui;Son, Chang-Hyo;Oh, Hoo-Kyu
    • Proceedings of the SAREK Conference
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    • 2005.11a
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    • pp.353-358
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    • 2005
  • The heat transfer and pressure drop of supercritical $CO_2$ cooled in a helically coiled tube was investigated experimentally. The experiments were conducted without oil in the refrigerant loop. The experimental apparatus of the refrigerant loop consist of receiver, a variable speed pump, a mass flowmeter, a pre-heater, a gas cooler(test section) and an isothermal tank. The test section is a helically coiled tube in tube counter flow heat exchanger with $CO_2$ flowed inside the inner tube and coolant( water) flowed along the outside annular passage, It was made of it copper tube with the inner diameter of 4.55[mm]. the outer diameter of 6.35 [mm] and length of 10000 [mm]. The refrigerant mass fluxes were $200^{\sim}600$ [kg/m2s] and the inlet pressure of gas cooler varied from 7.5 [MPa] to 10.0 [MPa]. The main results are summarized as follows : The heat transfer coefficient of supercritical $CO_2$ increases, as the cooling pressure of gas cooler decreases. And the heat transfer coefficient increases with the increase of the refrigerant mass flux. The pressure drop decreases in increase of the gas cooler pressure and increases with increase the refrigerant mass flux.

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