• Korean Journal of Clinical Pharmacy
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• v.32 no.3
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• pp.178-184
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• 2022

Background: Migraine is one of the leading causes of poor quality of life and disability, and migraine incidences in pediatrics are increasing. Proper medication is important for the preventive and acute treatment of migraine. This study aimed to identify the current status of prescribed medication in pediatric patients with migraine. Methods: We used data from a sample of pediatric patients from the Health Insurance Review and Assessment Service (HIRA-PPS-2018) and analyzed the status of prescription drugs and frequency of visits to medical institutions with migraine diagnoses in pediatric patients. Results: A total of 12,228 pediatric patients diagnosed with migraine during 2018 were analyzed. Among these patients, 7,170 (58.64%) were girls and 9,510 (77.77%) were adolescents. Additionally, 9,157 patients (74.89%) received acute treatment, and 592 patients (4.84%) received combination therapy with analgesics and triptans. Acetaminophen for acute treatment and flunarizine for preventive treatment were the most commonly prescribed. In most children and adolescents, acute treatment drugs were prescribed for less than 14 days. Conclusion: Analgesics, such as acetaminophen or non-steroidal anti-inflammatory drugs, were prescribed frequently for acute treatment in pediatric patients with migraine. The drug prescription duration was within the recommended range, indicating a low risk of overdose. For preventive treatment, clinically studied medication for pediatric patients with migraine was used.

• Proceedings of the KIPE Conference
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• 2020.08a
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• pp.109-111
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• 2020

본 논문에서는 ESS용 전류원 Dual-Active-Bridge 컨버터의 저 부하 및 고 부하에서의 효율 향상을 위한 하이브리드 스위칭 알고리즘을 제안하고자 한다. 전류원 DAB 컨버터는 인터리브 구조를 이용하여 배터리 단의 입력 전류 리플을 저감할 수 있고, 전력 변환 효율 개선을 위한 다양한 제어 변수를 도입할 수 있는 등의 장점으로 인해 DC 마이크로그리드에서 ESS용 절연형 양방향 DC/DC 컨버터로 주목받고 있다. 그러나 전류원 DAB에서 종래의 전력 제어 방법인 펄스폭 변조 방식과 위상천이가 결합된 방법 (PWM plus Phase Shift, PPS)의 경우 저 부하 조건에서 높은 피크 전류로 인해 도통 손실이 크며, 펄스폭 변조 방식과 이중 위상천이가 결합된 방법(PWM plus Dual Phase Shift, PPDPS)의 경우 고 부하 조건에서 영전압 스위치 영역이 좁아져 효과적이지 않다. 따라서 본 논문에서는 2차 측의 펄스폭과 위상천이를 독립적으로 제어하는 하이브리드 스위칭 알고리즘을 통해 순환전류를 감소시키고 영전압 스위치 영역을 확장시켜 저 부하 및 고 부하 모두에서 효율을 향상시키고자 한다. 1-kW급 전류원 DAB 컨버터 시작품을 통해 제안된 하이브리드 스위칭 알고리즘의 효율성과 타당성을 검증한다.

• Korean Journal of Agricultural Science
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• v.50 no.4
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• pp.817-828
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• 2023

Deteriorating soil physical properties and increasing soil pathogens due to the continuous cultivation of field crops are the leading causes of productivity deterioration. Crop rotation, soil heat treatment, and chemical control are used as pest control methods; however, each has limitations in wide application to domestic agriculture. In particular, chemical control requires improvement due to direct exposure to sterilizing solution, odor, and high-intensity work. To improve the overall domestic agricultural environment, the problems of time and cost, such as field maintenance and cultivation scale, must be addressed; therefore, mechanization technology for chemical control must be secured to derive improvement effects in a short period. Most related studies are focused on the control effect of the DMDS (dimethyl disulfide) sterilizer, and research on the performance of the sterilization spray device has been conducted after its introduction in Korea, but research on the corrosion suitability of the material is lacking. This study conducted a corrosion test to secure the corrosion resistance of a soil sterilizer injection pump, and a mechanical failure mode by corrosion by the material was established. The corrosion test comprised operation and neglect tests in which the sterilizing solution was circulated in the pump and remained in the pump, respectively. As a result of the corrosion test, damage occurred due to the weakening of the mechanical strength of the graphite material, and corrosion resistance to aluminum, stainless steel, fluororubber, and PPS (polyphenylene sulfide) materials was confirmed.

• Physical Therapy Korea
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• v.7 no.2
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• pp.76-87
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• 2000

Delayed onset muscle soreness (DOMS) is a common problem that can interfere with rehabilitation as well as activities of daily living. The purpose of this study was to determine the effects of both transcutaneous electrical nerve stimulation (TENS) and microcurrent electrical neuromuscular stimulation (MENS) on DOMS, Twenty-seven untrained and male volunteer subjects were randomly assigned to one of three treatment groups: 1) a group that received TENS (7 Hz), 2) MENS (60 ${\mu}A$, .3 pps) or 3) a control group that received no treatment. Subjects performed repeated eccentric exercise of the non-dominant forearm flexor muscle with submaximal intensity by the simply designed eccentric exercise devices. Treatments were applied after 24 hours and 48 hours. Subjects attended on two consecutive days for treatment and measurement of elbow flexion, extension, resting angle (universal goniometer), and pain (visual analogue scale: VAS) on a daily basis. Measurements were taken after treatment. Analysis of results were as follows; 1) There were no significant differences between TENS and MENS by one-way repeated ANOVA, 2) The t-test for pain, resting, flexion and extension angle revealed significant differences within TENS group, 3) The t-test for resting angle revealed significant differences within MENS group.

• Journal of Korean Biological Nursing Science
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• v.15 no.3
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• pp.99-106
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• 2013

Purpose: The purpose of this study was to examine the effect on plasma beta endorphin concentration level and the influences on pain score of transcutaneous electrical nerve stimulation (TENS) mediation to patients During a prostate needle biopsy. Methods: TENS was administered to only the experimental group. The electric current was given in high frequency (40-100 pps) and low intensity ($2-50{\mu}s$) from the waiting room stage until the end of the procedure. The average time spent was 35 minutes. Following 10 minutes of retention in the rectum, there was a biopsy. In two groups, the pain score was assessed twice when vas pain penetrated into the rectum, during the needle biopsy. The Beta endorphin concentration level was assessed through blood gathering 2 times in the Nuclear Medicine Labs before and after the test. Results: There was not much difference in pain levels from both groups when a microscope probe penetrated into the rectum and in the time when tissues were collected. However, the average overall pain level was reduced during those two procedures. The plasma beta endorphin level was increased in the TENS medicated group compared with the unmedicated group after the procedures were completed. Conclusion: The research indicates that TENS was desirable to be considered as a non-invasive method for controlling pain.

• The Journal of Society for e-Business Studies
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• v.8 no.3
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• pp.69-86
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• 2003

A Protection Profile(PP) is a common security and assurance requirements for a specific class of Information Technology security products such as firewall and smart card. A PP should be included "TOE(Target of Evaluation) Security Environment", which is consisted of subsections: assumptions, treat, organizational security policies. This paper presents a new threats statement generation method for developing TOE security environment section of PP. Our survey guides the statement of threats in CC(Common Criteria) scheme through collected and analysed hundred of threat statements from certified and published real PPs and CC Tool Box/PKB that is included a class of pre-defined threat and attack statements. From the result of the survey, we present a new asset classification method and propose a threats statement generation model. The former is a new asset classification method, and the later is a production rule for a well formed statement of threats.

• The Journal of Society for e-Business Studies
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• v.16 no.1
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• pp.101-116
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• 2011

As e-Commerce and national public procurement have been enabled, needs of supplier management and evaluation system for national public procurement has been growing. Enterprises have constructed and operated supplier relationship management system, in order to automate and increase their supply chain processes by managing the strategic assessment of relationships with external partners. Recently, PPS(Public Procurement Service) in Korea is introducing the concept of SRM to ensure the fairness of public procurement and to strengthen the competitiveness of the national public procurement and public procurement. For this purpose, it is necessary to establish supplier evaluation management and decision support process to allow a transparent supplier selection. In this paper, we present an evaluation method for transparent and objective public procurement. We also present a method for purchase decision support.

• Journal of the Korean Academy of Clinical Electrophysiology
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• v.3 no.1
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• pp.49-59
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• 2005

This study assigns each 8 of 24 normal persons to control group(Group I), strength increase group(Group II) and endurance increase group(Group III) to analyze differences in changes of strength and endurance with surface electromyography and kinetics according to application modes of neuromuscular electrical stimulation(NMES). Group I had not any treatment, group II performed 15 repeated contraction with 60% intensity of maximal voluntary isometric contraction(MVIC) by setting 10-sec on time and 50-sec off time and group III conducted 30 repeated contraction with 30% intensity of MVIC by setting 10-sec on time and 20-sec off time. For neuromuscular electrical stimulation, 2,500 Hz of Russian current, 35 pps of pulse rate and 200 of pulse width. Neuromuscular electrical stimulation was conducted by five times for total 4 weeks. Before and after experimentmotor unit action potential of vastus medialis, rectus femoris and vastus lateralis were measured with sEMG, median frequency(MDF) was analyzed, and thus the following results were obtained. There was significant difference in the period of measuring vastus medialis and rectus femoris in change of MDF and interaction among groups with analysis of surface electromyography before and after neuromuscular electrical stimulation(p<.001) and in particular, there was a remarkable change among groups according to the period of measurement. In conclusion, NMES influenced changes of strength and endurance according to its application modes and in particular, it was found that strength increment application had a significant influence on strength increment in applying short-time NMES.

• Journal of the Korean Academy of Clinical Electrophysiology
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• v.7 no.1
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• pp.1-6
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• 2009

Purpose : We investigated the effects of microcurrent(MC) electrical stimulation on each intensity($100{\mu}A,\;200{\mu}A,\;500{\mu}A$ - 30pps frequency was same) on delayed onset muscle soreness(DOMS). Methods : Subjects were assigned randomly divided into three groups of eight for three different treatment protocoals($100{\mu}A,\;200{\mu}A,\;500{\mu}A$-experimental groups). Twenty-four healthy males and females subjects were participated in this study. All subjects performed eccentric exercise of elbow flexor(biceps brachii) until exhausted. The measured items of elbow flexor muscle strength were Nicholas Manual Muscle Taster(NMMT). The measured items of elbow joint range of motion ROM) were Goniometer. The measured items of elbow flexor muscle pain were visual analogue scale(VAS). Treatment were applied at 30 minute exercise after and again at 24 hours and at 48 hours and at 72 hours after. Measurements were taken after treatment. Analysis of Results using repeated measures analysis of variance(ANOVA) and post hoc tests were as follows: two-way ANOVA with repeated measurement for muscle strength, flexion ROM, extension ROM and VAS. Results : This results showed eccentric exercise casused DOMS, DOMS response to eccentric exercise were reduces by microcurrent therapy. DOMS was significant decreased at $100{\mu}A,\;200{\mu}A,\;500{\mu}A$. Muscle strength was significant difference at all intensity. Elbow flexion ROM was significant difference at all intensity but elbow extension ROM was insignificant difference at all intensity. VAS score was significant difference at $100{\mu}A$ and $500{\mu}A$ but insignificant difference at $200{\mu}A$. All experimental groups showed insignificant difference with all intensity MENS. Conclusion : These findings indicate that microcurrent therapy is had effect on recovery from exercise induced muscle damage. In our's suggestion, microcurrent therapy is particularly more appropriate therapeutic modality.

• Journal of the Korean Academy of Clinical Electrophysiology
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• v.6 no.1
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• pp.43-55
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• 2008

The purpose of this study was to investigate the effect of microcurrent stimulation intensity($50{\mu}A,\;100{\mu}A,\;300{\mu}A$ - 5 pps pulse frequency was same) on wound healing in rat. Sixty male Korean rats were randomly divided into 4 groups of 15 for 4 different treatment protocols(none-control group, $50{\mu}A,\;100{\mu}A,\;300{\mu}A$ experimental groups). Experimental 20 mm linear wound were made and all animals in the experimental groups were received microcurrent stimulation once a day for 20 minutes until sacrifice days(1st day, 3rd day, 6th day). A vernier caliper was used to measure a wound healing length and an optical microscope was used to determine any histological changes. The repeated measures two-way ANOVA was used for statistical differences in wound healing length. Experimental results were as follows: 1. In the examination with the naked eye, all groups showed similar changes until 1st day. But from 3rd day, a little intercellular fluid soaked through wound region in control group. In experimental groups, little intercellular fluid soaked through wound region, and swelling and redness did not appear. 2. Wound length of experimental $50{\mu}A$ group was significantly decreased than control group(p<0.001). And in the aspect of application period, wound length was significantly decreased in 3th, 6th day than 1st day and 6th day than 3th day (p<0.001). In conclusion, it has been found that the microcurrent stimulation had a positive effect on wound healing. And $50{\mu}A$ stimulation intensity was more effective than other intensities($100{\mu}A,\;300{\mu}A$) in wound healing. Also, low-intensity microcurrent stimulation was more effective on the purpose of wound healing.