• Asian Journal of Business Environment
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• 제5권4호
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• pp.59-66
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• 2015

Purpose - The aim of the study is to analyze the impact of the European Union's (EU) focus on innovation and consumption, after the EU Eastern enlargement, on trade, investment, and technology cooperation patterns of Korea to formulate a pan-European marketing strategy, with a special emphasis on the mobile phone industry. Research design, data, and methodology - This study compares the intersection of the pivotal areas in the markets in the "post-new normal" era to identify outlets to commercialize development and innovation in this region. The EU would like to realize potential trade and investment opportunities with the Central European Economic Community (CEEC) from this enlargement. Results - The study analysis suggests a positive impact for innovation and consumption from the EU Eastern enlargement on trade, investment, and technology cooperation patterns of Korea to formulate a pan-European marketing strategy with a special emphasis on the mobile phone industry or motorcar e-strategy. Conclusions - Due to the evolving close interdependencies some hubs have emerged between regional, small markets and the central, larger ones such as Germany and France.

• The Journal of Asian Finance, Economics and Business
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• 제7권12호
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• pp.509-513
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• 2020

Network marketing in Indonesia, especially in a time of crisis, is massively rising and has become a popular opportunity among other industries. Network marketing organizations, consists of partnership and trust, a community of connections and contact between individuals. This article has tried to examine the potential strategy to mitigate low trust in network marketing organizations specifically in the Indonesia market, where no studies on the subject has been done before. In doing this research assignment employed a secondary research methodology by reviewing previous academic literatures, by exploration and evaluation. For the purpose, 6 main articles and 25 relevant supporting articles were selected, there is an interesting and prominent research in an effort to repair trust in the perspective of the organization's efforts to build trust and control trust framework in strategy trust repair. The result of this analysis showed that the application of trust-building activities studies reveals how trust-building behavior is related to controls and how the efforts towards fostering subordinate cooperation are motivated by different types of controls and display of trustworthiness. It can be concluded that by implementing this trust repair model consistently and with a full commitment, it can gradually restore people's trust in the network marketing industry, sustain industry existence and exalted purpose of this industry can be achieved.

• 환경영향평가
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• 제19권6호
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• pp.591-605
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• 2010

Cool roofs are currently being emerged as one of important mechanism to save energy in relation to the building. This paper reviews worldwide experiences (USA, Japan and EU etc) for the potential benefits cool roofs offer in relation to building energy saving for comparison purposes. It is confirmed that there is a significant potential to the energy saving by introducing the cool roof in a Korean climate because of similarity in terms of HDD (Heating Degree Day) and CDD (Cooling Degree Day) as those countries reviewed. Such a comparative study highlights that the type of measurements performed and the quantitative parameters reported from the countries should be standardized in Korean context in order to implement further comparable experiments for scientifically sound investigations. It is anticipated that this research output could be used as a valuable reference in implementing a Nation-wide cool roofing strategy in the central and local governments since a suitable technical, more objective direction has been proposed based on the measured, fully quantitative performance of the involved components of a cool roof system in the global context. From this critical review, a very important step has been made concerning the practicality of cool roof in Korean context. Ultimately, the suggestion in this paper will greatly contribute to opening new possibilities for introducing cool roof in this country, proposed as an initial aim of this paper.

• 한국철도학회논문집
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• 제7권3호
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• pp.264-270
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• 2004

The hub-and-spoke strategy is widely used in the field of transportation. At the field of rail transportation, however, it is difficult that we find an application case of this strategy because of modal characteristics. According to the fast growth of containerization and the development of transshipment technology, presently, the hub-and-spoke strategy is introduced by operators on actual European rail freight transportation. However, it is hardly to find empirical studies evaluating the applicability of transportation strategy. In this context, this study analyzed the applicabilities of hub-and-spoke strategy in the actual network of European rail freight. For the application and evaluation of the characteristics of hub-and-spoke strategy, it utilized a service network design model for rail freight. Utilizing this model, it analyzed the efficiency of furnished rail freight services, the potential locations of hubs, the characteristics of O-D flows by the types of trains and service links, and the types of paths of O-D flows. Finally, it proposed some implications and the further study topics.

• International Journal of Naval Architecture and Ocean Engineering
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• 제9권6호
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• pp.598-612
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• 2017

The recently developed Harmonic Polynomial Cell (HPC) method has been proved to be a promising choice for solving potential-flow Boundary Value Problem (BVP). In this paper, a flux method is proposed to consistently deal with the Neumann boundary condition of the original HPC method and enhance the accuracy. Moreover, fixed mesh algorithm with free surface immersed is developed to improve the computational efficiency. Finally, a two dimensional (2D) multi-block strategy coupling boundary-fitted mesh and fixed mesh is proposed. It limits the computational costs and preserves the accuracy. A fully nonlinear 2D numerical wave tank is developed using the improved HPC method as a verification.

• Nuclear Engineering and Technology
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• 제47권6호
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• pp.719-728
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• 2015

Following the Fukushima accident, a special safety inspection was conducted in Korea. The inspection results show that Korean nuclear power plants have no imminent risk for expected maximum potential earthquake or coastal flooding. However long- and short-term safety improvements do need to be implemented. One of the measures to increase the mitigation capability during a prolonged station blackout (SBO) accident is installing injection flow paths to provide emergency cooling water of external sources using fire engines to the steam generators or reactor cooling systems. This paper illustrates an evaluation of the effectiveness of external cooling water injection strategies using fire trucks during a potential extended SBO accident in a 1,000 MWe pressurized water reactor. With regard to the effectiveness of external cooling water injection strategies using fire engines, the strategies are judged to be very feasible for a long-term SBO, but are not likely to be effective for a short-term SBO.

• International Journal of Computer Science & Network Security
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• 제22권4호
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• pp.292-298
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• 2022

Femtocell networks can be a potential method for increasing the capacity of LTE networks, especially in indoor areas. However, unplanned deployment of femtocells results in co-tier interference and cross-tier interference problems. The interference reduces the advantages of implementing femtocell networks to a certain extent. The notion of Fractional Frequency Reuse (FFR) is proposed in order to reduce the impact of interference on the system's performance. In this paper, a dynamic approach for efficiently partitioning the spectrum is suggested. The goal is to enhance the capacity of femtocells, which will improve the performance of the system. The suggested strategy allocates less resources to the macrocell portion of the network, which has a greater number of femtocells deployed to maximize the utilization of available resources for femtocell users. The spectrum division would be dynamic. The proposed strategy is evaluated through a simulation using MATLAB tool. In conclusion, the results showed that the proposed scheme has the potential to boost the system's capacity.

• Journal of Electrical Engineering and Technology
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• 제12권1호
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• pp.45-52
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• 2017

This paper deals with the operation strategy of reactive power in a multi-infeed HVDC (MIHVDC) system, in which several converters are connected to the same or nearby separate AC buses. The potential problems concerning a MIHVDC system when feeding a weak AC network are as follows: the need for coordination of the recovery control, the possibility of voltage instability or low quality of the area connected to the MIHVDC system, and the risk of mutual commutation failures. These problems in MIHVDC systems are similar to those in single-infeed HVDC (SIHVDC) systems, but the differences with the phenomenon of the SIHVDC system are the interactions between converters. The main reason for the potential problems of HVDC systems (MIHVDC or SIHVDC) is voltage variation; therefore, to mitigate the voltage variations, the performances of the HVDC system should be enhanced. Consequently, to mitigate the potential problems of MIHVDC systems, several solutions are suggested in this study, including installing STATCOM and installing a line arrester on the tower. The study results will be applied to a multi-infeed HVDC system in Korea.

• BMB Reports
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• 제51권11호
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• pp.545-546
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• 2018

With emerging evidence on the importance of non-cell autonomous toxicity in neurodegenerative diseases, therapeutic strategies targeting modulation of key immune cells. including microglia and Treg cells, have been designed for treatment of ALS and other neurodegenerative diseases. Strategy switching the patient's environment from a pro-inflammatory toxic to an anti-inflammatory, and neuroprotective condition, could be potential therapy for neurodegenerative diseases. Mesenchymal stem cells (MSCs) regulate innate and adaptive immune cells, through release of soluble factors such as $TGF-{\beta}$ and elevation of regulatory T cells (Tregs) and T helper-2 cells (Th2 cells), would play important roles, in the neuroprotective effect on motor neuronal cell death mechanisms in ALS. Single cycle of repeated intrathecal injections of BM-MSCs demonstrated a clinical benefit lasting at least 6 months, with safety, in ALS patients. Cytokine profiles of CSF provided evidence that BM-MSCs, have a role in switching from pro-inflammatory to anti-inflammatory conditions. Inverse correlation of $TGF-{\beta}1$ and MCP-1 levels, could be a potential biomarker to responsiveness. Thus, additional cycles of BM-MSC treatment are required, to confirm long-term efficacy and safety.

• Biomolecules & Therapeutics
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• 제17권1호
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• pp.1-11
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• 2009

Since the Committee for Proprietary Medicinal Products (CPMP) of the European Union issued in 1997 a "points to consider" document for the assessment of the potential for QT interval prolongation by non-cardiovascular agents to predict drug-induced torsades de pointes (TdP), the QT liability has become the critical safety issue in the development of pharmaceuticals. As TdP is usually linked to delayed cardiac repolarization, international guideline (ICH S7B) has advocated the standard repolarization assays such as in vitro IKr (hERG current) and in vivo QT interval, or in vitro APD (as a follow up) as the best biomarkers for predicting the TdP risk. However, the recent increasing evidence suggests that the currently used above biomarkers and/or assays are not fully predictive for TdP, but also does not address potential new druginduced TdP due to the selective disruption of hERG protein trafficking to the cell membrane or VT and/or VF with QT shortening. There is, therefore, an urgent need for other surrogate markers or assays that can predict the proarrhythmic potential of drug candidate. In this review, we provide an ideal pre-clinical strategy to predict the potentials of QT liability and lethal arrhythmia of the drug candidates with recent issues in this field in mind, not at the expense of discarding therapeutically innovative drugs.