• 제목/요약/키워드: Postoperative Period

검색결과 1,563건 처리시간 0.031초

Tumor Necrosis Factor-alpha and Apoptosis Following Spinal Nerve Ligation Injury in Rats

  • Kim, Sung-Hoon;Nam, Jae-Sik;Choi, Dae-Kee;Koh, Won-Wook;Suh, Jeong-Hun;Song, Jun-Gol;Shin, Jin-Woo;Leem, Jeong-Gil
    • The Korean Journal of Pain
    • /
    • 제24권4호
    • /
    • pp.185-190
    • /
    • 2011
  • Background: Spinal nerve ligation (SNL) injury in rats produces a pain syndrome that includes mechanical and thermal allodynia. Previous studies have indicated that proinflammatory cytokines such as tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) play an important role in peripheral mediation of neuropathic pain, and that altered dorsal root ganglion (DRG) function and degree of DRG neuronal apoptosis are associated with spinal nerve injury. The present study was conducted to evaluate the expression of TNF-${\alpha}$ and the extent of apoptosis in the dorsal root ganglion after SNL in rats. Methods: Sprague-Dawley rats were subjected to SNL of the left L5 and L6 spinal nerves distal to the DRG and proximal to the formation of the sciatic nerve. At postoperative day 8, TNF-${\alpha}$ protein levels in the L5.6 DRG were compared between SNL and naive groups using ELISA. In addition, we compared the percentage of neurons injured in the DRG using immunostaining for apoptosis and localization of activated caspase-3. Results: SNL injury produced significant mechanical and cold allodynia throughout the 7-day experimental period. TNF-${\alpha}$ protein levels were increased in the DRG in rats that had undergone SNL ($12.7{\pm}3.2$ pg/100 ${\mu}g$, P < 0.001) when compared with naive rats ($4.1{\pm}1.4$ pg/100 ${\mu}g$). The percentage of neurons or satellite cells co-localized with activated caspase-3 were also significantly higher in rats with SNL than in naive rats (P < 0.001, P < 0.05, respectively). Conclusions: SNL injury produces mechanical and cold allodynia, as well as TNF-${\alpha}$ elevation and apoptosis in the DRG.

아킬레스건 파열의 수술적치료 -단단 봉합술 및 건외막피복술- (Surgical Treatment of Ruptured Achilles Tendon - End-to-end suture & Paratendinous wrapping)

  • 황득수;이원석;김경천
    • 대한정형외과스포츠의학회지
    • /
    • 제1권2호
    • /
    • pp.138-142
    • /
    • 2002
  • 목적: 스포츠와관련된급성아킬레스건파열의직접봉합및건외막피복술의결과및예후를평가하였다. 대상및방법: 1997년부터2001년까지수술후1년이상추시가능했던21예를대상으로하였다. 30대가$55\%$로가장많았으며축구후에생긴파열이5예로가장많았고, 양측이간격을두고파열된경우가2예로확인되었다. 수술은수상후1주이내에시행하였으며, 단단봉합술후주위건외막조직을충분히봉합하여혈액순환을최대한유지한상태로봉합부를피복하였다. 수술후슬관절을25도굴곡, 족관절은족저굴곡된상태로6주간장하지석고고정후2주간격으로단하지석고고정및족관절첨족을기능적위치로전환하여10주째90도족배굴곡상태로회복시켰다. 결과는Hooker의기준을이용하여수술후평균28개월에평가하였다. 결과: 환측이정상측에비해발뒤꿈치-지면거리가평균0.7cm 감소하였고, 20회체중부하족저굴곡후에는0.8 cm 감소하였으며, 하퇴둘레는0.3 cm 감소하였고, 능동적운동범위는족배굴곡과족저굴곡이각각3도와5도가감소하였다. 수술결과는1 6예에서우수, 5예에서양호를보였으며재파열이나상처부위괴사및감염의후유증은없었다. 결론: 아킬레스건파열의단단봉합술후주위건외막조직의충분한피복봉합은건의치유와수술후유착방지에, 그리고수술후주기적족관절족배교정은잔여첨족변형의예방에좋은치료방법이다

  • PDF

단축 Scarf 절골술을 이용한 무지 강직증의 치료 (Shortening Scarf Osteotomy for Treatment of Hallux Rigidus Deformity)

  • 이영현;안길영;남일현;이태훈;이용식;김대근;이영훈
    • 대한족부족관절학회지
    • /
    • 제20권4호
    • /
    • pp.152-157
    • /
    • 2016
  • Purpose: To evaluate the effect of shortening scarf osteotomy on pain relief and range of motion (ROM) of the first metatarsophalangeal joint in hallux rigidus patients. Materials and Methods: Twenty-three cases of 19 patients who had been treated with shortening scarf osteotomy for the hallux rigidus between January 2007 and December 2013 were reviewed. The mean follow-up period was 21.4 months, and the mean age was 59.2 years. The first metatarsal bone was shortened until the ROM of the first metatarsophalangeal joint was greater than $80^{\circ}$ or $40^{\circ}$ of dorsiflexion. The length shortened by scarf osteotomy was measured. The authors also measured and compared the joint interval difference of the standing foot using an anteroposterior radiography. Moreover, the difference of ROM of the first metatarsophalangeal joint between the preoperative and final follow-up periods was also compared. The clinical results were evaluated and compared using the American Orthopaedic Foot and Ankle Society (AOFAS) scoring system and visual analogue scale (VAS) score. Results: The mean shortening length was about 6.5 mm (range, 4~9 mm). The joint space has been increased to 1.8 mm, and the ROM of the first metatarsophalangeal joint has also been increased to $18.4^{\circ}$ after the operation. In three cases, the postoperative ROM has been decreased to less $10^{\circ}$. The AOFAS score has been improved from 41.7 (range, 32~55) to 86.2 (range, 65~95), and the VAS score was also decreased from 3.7 (range, 3~5) to 1.3 (range, 0~3). Two cases have shown no decrease in pain even after the operation. Conclusion: Shortening scarf osteotomy was found to decrease joint pain by decompressing the pressure of the first metatarsophalangeal joint. This osteotomy also helped improve the ROM of the first metatarsophalangeal joint. Shortening scarf osteotomy can be considered one of the effective methods for joint preservation.

족관절 삼과 골절에서 전후방 유관나사 후과 고정술의 2년 추시 결과 (Two-Year Follow-up Results of Anteroposterior Cannulated Screw Fixation of Posterior Malleolar Fragment in the Trimalleolar Fracture)

  • 정성윤;이명진;정영훈
    • 대한족부족관절학회지
    • /
    • 제20권2호
    • /
    • pp.67-72
    • /
    • 2016
  • Purpose: The purpose of this study was to assess the 2-year follow-up results of patients with a trimalleolar fracture, who had undergone an anterior incision cannulated screw fixation of the posterior malleolar fragment, which had more than 25% of articular involvement or had no cortical continuity with the distal tibia. Materials and Methods: Among 28 patients with a trimalleolar fracture who had undergone fixation of the posterior malleolar fragment between February 2005 and February 2010, 14 patients, who underwent an anterior incision cannulated screw fixation of posterior malleolar fragment and were followed-up for more than 2 years, were selected. The postoperative clinical and radiological findings immediately and at the 1- and 2-year follow-up were compared. The clinical findings were evaluated as American Orthopaedic Foot and Ankle Society (AOFAS) score. The radiological assessment was evaluated as the maintenance of reduction, period to bone union, and the presence of nonunion, malunion, and complications. Results: The clinical outcome by mean AOFAS score revealed 83.0 points in the group with preoperative displacement below 2 mm and 80.7 points in the group with preoperative displacement above 2 mm postoperatively. The mean AOFAS score was 91.7 and 93.1 points in the group with preoperative displacement below 2 mm on 1- and 2-year follow-up, respectively, and 89.8 and 91.7 points in group with the preoperative displacement above 2 mm on 1- and 2-year follow-up, respectively. After a 2-year follow-up among 14 cases selected for this study, 13 cases showed an excellent reduction state and only 1 case (7.1%) showed a displacement of more than 2 mm. No complication were encountered in the group with preoperative displacement below 2 mm. On the other hand, among 8 patients in the group with preoperative displacement above 2 mm, there were 3 with limitations of the range of motion of the ankle joint (37.5%) and 1 post-traumatic arthritis (12.5%) at the 2-year follow-up. Conclusion: Anterior incision cannulated screw fixation of the posterior malleolar fragment could be a valuable method for the treatment of trimalleolar fractures that provides satisfactory results.

골격성 III급 부정교합 환자에서 하악골의 이동량과 교합평면의 변화에 따른 술 후 안정성 (Skeletal Stability after Orthognathic Surgery in Severe Skeletal Class III Malocclusion Patients according to Changes in Anteroposterior Discrepancy and Occlusal Planes)

  • 이정한;김성희;백영재;안경용;황대석;김용덕;김욱규
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • 제34권6호
    • /
    • pp.404-412
    • /
    • 2012
  • Purpose: The purpose of this study was to evaluate postsurgical facial hard tissue stability after orthognathic surgery with/without posterior impaction in skeletal class III malocclusion patients, and to evaluate the horizontal relapse tendency, according to changes in anteroposterior discrepancy and occlusal planes. Methods: Ninety patients, who had undergone orthognathic surgery in Pusan National University Dental Hospital, were enrolled in this study. Three main groups were classified as follows: Thirty patients underwent mandibular setback bilateral sagittal split ramus osteotomy (BSSRO) only (BSSRO group, BG); another thirty patients underwent mandibular setback BSSRO and Le Fort I osteotomy with posterior impaction (posterior impaction group, PG); and another thirty patients underwent mandibular setback BSSRO and Le Fort I osteotomy without posterior impaction (non-posterior impaction group, NPG). Preoperative (T0), immediate postoperative (T1) and six-month follow-up period (T2) lateral cephalograms were taken, and various parameters were measured. The analyses were done by linear and angular measurements between T0-T1 and T1-T2, to evaluate postsurgical facial hard tissue stability. Results: Mean horizontal relapse rates were distributed from 11.81% to 19.08%, and there were significant postsurgical changes (0.52 mm~2.44 mm) at the B point in all 3 groups. But, there were no statistical differences on relapse rate among BG, PG and NPG patients. Conclusion: In this study, the postsurgical stabilities of BSSRO and Le Fort I osteotomy with/without posterior impaction in skeletal class III malocclusion patients were acceptable. There were no significant statistical differences in mandibular stability according to changes in anteroposterior discrepancy and occlusal planes.

의사와 간호사의 외과적 손씻기에 관한 지식, 태도 및 실천에 대한 조사 연구 (A Survey on the Performance of Surgical Hand Scrubs)

  • 윤혜상
    • 대한간호학회지
    • /
    • 제26권3호
    • /
    • pp.591-604
    • /
    • 1996
  • The surgical hand scrub (SHS) is the single most important procedure in the prevention of post-operative wound infections and yet it remains the most violated of all infection control procedures. The purpose of this study was to gain an overview of SHS habits in operative th atre personnel and to determine knowledge and attitudes to identify whether there is a need for improvement. The subjects for this study included 79 doctors and 94 nurses working in the operative th atres of four hospitals in Incheon City and Kyungki Province. Related data were collected from July 25 to August 10, 1995 by the author. The data were analyzed using descriptive stat-istics and Chi-squre test. The results of the study are summarized as follows : 1. Nurses felt that they conducted SHS for a longer period of time than doctors did(X=20.1, P=.005). 2. Nurses and doctors had some knowledge of slip-ping rings off fingers and the length of nails, but they lacked knowledge on the duration of SHS, handwashing after an operation and on manicure. 3. There were many reasons given for insufficient SHS included : 1) because they were so busy (38%). 2) brushes were too harsh(19.7%). 3) operations were very simple(18.7%). 4) surgical latex gloves provide functional barrier(11.6%). 5) SHSs were troublesome(7.4%) 6) there were no clocks near the sinks(2.5%) and 7) the operative patients were administered antibiotics after operartion(2.1%). 4. Most of nurses and doctors considered SHS to be important in prevention against post operative infections. 5. Nurses were found to do a thorough SHS, but residents were found to neglect SHS. 6. Considering prevention against postoperative infections, most nurses and doctors considered aseptic techniques, environment-sanitary management and SHS more important than the use of antibiotics, the resistance of patients or the method of operation. 7. Half of the nurses and doctors(54.3%) considered surgical latex gloves to function well as a barrier. 8. Half of the nurses (56.4%) and doctors(51.9%) learned SHS as part of the curriculum in their school education and the rest(nurses : 95.7%, doctors : 74.7%) learned SHS as part of their In Service Education. In conclusion, these findings suggest a need to develop an educational program on surgical hand scrub and hospital infection control for surgical personnels, to install clocks near the hand scrub sinks, to consider a violation report for negligent surgical hand scrubs, and to develop a soft brush for hand scrubs in order to increase performance of the surgical hand scrub.

  • PDF

선천성 십이지장 폐쇄증의 임상적 고찰 (A Clinical Study of Congenital Duodenal Obstruction)

  • 허영수;서보양;권굉보
    • Journal of Yeungnam Medical Science
    • /
    • 제7권2호
    • /
    • pp.39-48
    • /
    • 1990
  • 저자들은 1986년 7월부터 1990년 6월까지 만 4년간 영남대학교 의과대학 외과학교실에 입원하여 수술로서 확진된 선천성 십이지장 폐쇄증 환자 16명을 대상으로 임상분석하여 다음과 같은 결론을 얻었다. 1. 총 16명중 남아 11 명, 여아 5명으로 남아에서 2.2배 호발하였으며 입원시 연령은 생후 1개월 이내가 13예로 81%를 차지하였다. 2. 선천성 십이지장폐쇄의 원인으로는 중장 이상회전이 8예(50%)로 가장 많았으며, 환상 췌장 6예, 제1형 십이지장폐쇄와 wind-sock기형이 각 1예였다. 그리고 환상췌장 1예에서 장이상회전이 공존하였다. 3. 총 16명중 미숙아 2명, 저체중아 6명이었으며, 2예에서 산모의 양수과다증이 존재하였다. 형제중 발생순위는 초산아가 9예로 가장 많았다. 4. 주요 임상증상으로는 구토가 15예로 거의 전례에서 나타났고 이중 12예가 담즙성이었다. 증상발현으로 전체환자의 56%가 생후 첫주내에 입원하였다. 5. 진단은 주증상과 단순복부촬영상 특징적인 쌍기포 소견을 봄으로 가능했으며 부분폐쇄가 의심되는 경우는 중장염전과의 조기감별을 위해 상부위장관 조영술 및 대장조영술을 시행하였다. 6. 중장이상회전 8예에서는 Ladd 술식 6예, Ladd술식에 장절제문합 1예, 염전을 풀고 Ladd술식 1예를 시행하였으며, 나머지 8예에서는 십이지장십이지장 문합술 4예, 십이지장공장 문합술 2예, Ladd술식에 십이지장십이지장 문합술 1예, 십이지장 격막 제거술 1예를 시행하였다. 술후 고농도 영양주입법은 5예에서 시행하였다. 7. 동반된 기형은 6명의 환자에서 10예가 발견되었으며, Down's 증후군 및 십이지장 전방 문맥이 각 2예로 가장 많았다. 8. 수술합병증은 총 5예(51%)로 창상감염 2예, 폐염 1예, 장폐쇄증 2예였다. 술후 사망하였던 경우는 단 한명도 없었으며 16명 모두 현재까지 특별한 문제없이 건강하게 자라고 있다.

  • PDF

완전 구강 회복술 (Full Mouth Rehabilitation)

  • 이승규;이성복;권긍록;최대균
    • 구강회복응용과학지
    • /
    • 제16권3호
    • /
    • pp.171-185
    • /
    • 2000
  • The treatment objectives of the complete oral rehabilitation are : (1) comfortably functioning temporomandibular joints and stomatognathic musculature, (2) adherence to the basic principle of occlusion advocated by Schuyler, (3) anterior guidance that is in harmony with the envelope of function, (4) restorations that will not violate the patient's neutral zone. There may be many roads to achieving these objectives, but they all convey varing degrees of stress and strain on the dentist and patient. There are no "easy" cases of oral rehabilitation. Time must be taken to think, time must be taken to plan, and time must be taken to perform, since time is the critical element in both success and failure. Moreover, a systematized and integrated approach will lead to a prognosis that is favorable and predictable. This approach facilitates development of optimum oral function, comfort, and esthetics, resulting in a satisfied patient. Such a systematized approach consists of four logical phase : (1) patient evaluation, (2) comprehensive analysis and treatment planning, (3) integrated and systematic reconstruction, and (4) postoperative maintenance. Firstly, we must evaluate the mandibular position. The results of a repetitive, unstrained, nondeflective, nonmanipulated mandibular closure into complete maxillomandibular intercuspation is not so much a "centric" occlusion as it is a stable occlusion. Accordingly, we ought to concern ourselves less with mandibular centricity and more with mandibular stability, which actually is the relationship we are trying to establish. The key to this stability is intercuspal precision. Once neuromuscular passivity has been achieved during an appropriate period of occlusal adjustment and provisionalization, subsequent intercuspal precision becomes the controlling factors in maintaining a stable mandibular position. Secondly, we must evaluate the planned vertical dimension of occlusion in relationship to what may now be an altered(generally diminished), and avoid the hazard of using such an abnormal position to indicate ultimate occlusal contacting points. There are no hard and fast rules to follow, no formulas, and no precise ratios between the vertical dimension of occlusion. Like centric relation, it is an area, not a point.

  • PDF

류마티스 관절염에 의한 고도의 무지 외반증과 소족지 갈퀴족 변형에 대한 중족골 종축 감압 절골술을 이용한 관절 보존술의 결과 (Result of Joint Preserving Surgery Using Axial Shortening Metatarsal Osteotomy for the Treatment of Severe Hallux Valgus and Claw Toes Deformity in Advanced Rheumatoid Arthritis)

  • 남일현;안길영;문기혁;이영현;최성필;김호규;오동호
    • 대한족부족관절학회지
    • /
    • 제16권1호
    • /
    • pp.47-52
    • /
    • 2012
  • Purpose: The purpose of this study is to evaluate the effect of axial shortening metatarsal osteotomy on the treatment of advanced rheumatoid arthritis patients with severe hallux valgus and claw toe deformity of lesser toes which is used for preserving the metatarsophalangeal joint. Materials and Methods: From January 2005 to June 2009, 18 cases of axial shortening metatarsal osteotomy in advanced rheumatoid arthritis were reviewed ; all of them followed up for more than 2 years after surgical procedures and the mean follow up period was 3.4 years. We performed axial shortening Scarf osteotomy and Akin osteotomy for hallux valgus and Weil osteotomy with soft tissue release for claw toe of lesser toes, respectively. We measured preoperative and postoperative hallux valgus angle, each metatarsal shortening length and the range of motion of the metatarsophalangeal joints through radiographic and clinical examination and compared them each other. Clinical results were evaluated by American Orthopedic Foot and Ankle Society (AOFAS) score and subjective satisfaction of the patients. Results: The hallux valgus angle was reduced from the preoperative mean value of 44.8 degree to 9.0 degree postoperatively and the range of motion of the metatarsophalangeal joint of great toe and lesser toes was increased from the mean of 21.7 degree and 11.0 degree preoperatively to 38.0 degree and 32.5 degree, respectively at postoperation. Also, the mean AOFAS score was improved from 26.5 points to 67.4 points. Conclusion: Axial shortening osteotomy is a useful method to correct the deformity and preserve the metatarsophalangeal joint for severe hallux valgus and claw toe deformity in advanced rheumatoid arthritis.

잠김 압박 금속판을 이용한 근위 상완골 골절의 내고정술 (Internal Fixation of Proximal Humerus Fracture with Locking Compression Plate)

  • 박철현;박성혁;서재성
    • Clinics in Shoulder and Elbow
    • /
    • 제12권1호
    • /
    • pp.44-52
    • /
    • 2009
  • 목적: 상완골 근위부 골절에서 잠김 압박 금속판을 이용하여 치료한 후 그 임상적 및 방사선학적 결과를 알아 보고자 하였다. 대상 및 방법: 2005년 2월부터 2007년 9월까지 상완골 근위부 골절로 잠김 압박 금속판을 이용하여 치료받은 20명의 환자를 대상으로 하였다. 평균 연령은 60.6세였고, 평균 추시 기간은 22.3개월이었다. 임상적 결과는 Constant score 및 DASH score를 이용하여 평가하였고, 방사선학적 평가는 경간각을 이용한 Pavolainen의 방법과 상완 골두의 높이를 측정하여 평가하였다. 결과: 최종 추시 시 Constant score는 평균 75.3점이었고, 15예에서 양호 이상의 점수를 보였고, DASH score 평균 16.4점이었다. 경간각은 평균 $137.1^{\circ}$였으며 19예에서 양호 이상의 결과를 보였다. 전 예에서 골유합을 얻을 수 있었으며, 지연성 유합 및 부정 유합이 각 1예에서 관찰되었고 1예에서 나사못에 의한 자극을 보였다. 결론: 불안정성 상완골 근위부 골절에서 잠김 금속판을 이용한 내고정술은 임상적 및 방사선학적으로 양호한 결과를 보여 주었고, 적은 합병증을 나타내었으며 만족스런 정복과 안정적인 초기 고정력을 얻을 수 있어 조기에 관절 운동이 가능하였다. 잠김 압박 금속판을 이용한 내고정술은 불안정성 상완골 근위부 골절의 치료에 좋은 방법이라고 생각된다.