• 정신신체의학
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• 제8권1호
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• pp.65-71
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• 2000

연구목적 : 본 연구는 암컷 생쥐에서 출생직후 testosteorne에 노출시키면 testosterone과 연관된 통각억제계의 발달이 영향을 받으며 성인기의 testosterone 투여는 통각예민도를 감소시킨다는 가설을 검증하기 위하여 시행되었다. 방법 : 출생직후 testosterone에 노출시켜 남성화된 Institute for Cancer Research계 암컷생쥐 30마리와, 남성화 시키지 않은 정상 암컷생쥐 25 마리를 84일간 성장 시킨후 testosterone 1mg/kg를 1일 1회 3일간 투여하였다. testosterone 투여전후 통각 예민도를 tail flick latency로 실험 84일과 86일에 측정하였다. 1) 실험 84일째 기저통각 예민도는 남성화군이 $2.7{\pm}0.4$초로서 대조군의 $3.3{\pm}1.1$초에 비하여 유의하게 예민하였다. 2) 실험 84일째 testosterone 주사 후의 유해 감각 예민도는 남성화군이 $5.2{\pm}0.9$초로서 대조군의 $4.6{\pm}1.8$초에 비하여 유의하게 둔감하였고 두 군 모두에서 기저 통각 예민도에 비하여 유의하게 둔하여졌으나 남성화군에서 둔화의 정도가 유의하게 컸다. 3) 실험 86일째 testosterone 주사 전 통각 예민도는 남성화군이 $4.8{\pm}1.9$초로서 대조군의 $3.9{\pm}1.2$초에 비하여 유의하게 둔감하였다. 4) 실험 86일째 testosterone 주사 후 통각 예민도는 남성화군이 $5.9{\pm}0.9$초로서 대조군의 $4.9{\pm}1.5$초에 비하여 유의하게 둔감하였고 두군 모두에서 주사전에 비하여 유의하게 둔하여 졌으나 둔화의 정도에는 차이가 없었다. 5) 실험 84일과 비교하여 실험 86일째 주사전 통각 예민도의 변화는 남성화군이 $2.1{\pm}1.0$초로서 대조군의 $0.5{\pm}1.3$초에 비하여 유의하게 둔하여 졌으나 주사후 통각예민도의 변화는 유의하지 않았다. 결론 : 이상의 결과에서 저자는 testosterone 연관 통각억제계가 존재할 것이고 이 통각억제계의 발달은 신생아기에 testosterone 투여로 강화되며 성장후 이 통각억제계의 활성은 testosterone이 매개할 가능성을 제시한다.

• 대한한방내과학회지
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• 제33권4호
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• pp.476-484
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• 2012

Objectives : The purpose of this study was to report the clinical characteristics of glossodynia patients and effects of traditional Korean treatment on glossodynia and to gather data in order to carry out future study. Methods : We surveyed 40 glossodynia patients visiting the Department of Korean Internal Medicine of Stroke and Neurological Disorders Center, Kyung Hee University Hospital at Gangdong and analyzed their glossodynia questionnaires, examination results, and progression of symptoms. Results : In Glossodynia patients the average age was 62.4 years old. Glossodynia was more prevalent in females than males (5.67:1). Red tongue color, white fur, and fissured tongue were observed most often. The average glossodynia duration was 36.1 months and the average glossodynia degree was VAS 5.6. The most commonly appearing symptom was burning sense, and dryness of tongue. In Korean medicine diagnosis, Yin, deficiency, Tae-eum was most commonly diagnosed. In herbal medicine, Gamichungsim-tang was the most frequently prescribed. In laboratory tests, zinc deficiency was the most common result. In heart rate variability (HRV), average SDNN was 34.03 and average LF/HF ratio was 2.11. Of 40 patients, 23 completed treatment and their pain was relieved from average VAS 5.52 to VAS 3.63. Pre-and post-treatment results showed a significant difference. The average duration of treatment was 34.91 days. Conclusions : The results of this study suggest that Korean medical approach and treatment for glossodynia could be effective. Further study should be conducted for more valuable information.

• Journal of Preventive Medicine and Public Health
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• 제33권3호
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• pp.334-342
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• 2000

이 연구는 당일수술을 실시하고 있지 않은 병원에서 당일수술이 가능한 질병으로 입원하고 있는 환자를 대상으로 당일수술에 대한 인지도와 선호도를 조사하고, 당일수술 가능 질병의 평균 재원일수를 분석하며, 마취 후 퇴원점수체계를 이용한 시간대별 퇴원 가능한 환자의 비율을 분석하여 당일수술 가능여부를 판단하기 위하여 실시되었다. 자료수집은 1999년 2월 1일부터 동년 3월 31일까지 $\bigcirc\bigcirc$대학교 의과대학 부속병원에 입원하여 백내장, 편도선 비대, 탈장, 사시, 안검하수, 담석증, 질, 치루로 수술 받은 환자 353명을 대상으로 하였다. 자료 수집 방법은 설문지를 이용하여 설문과 면담을 하였고, 간호사용 마취 후 퇴원점수체계(PADS)를 이용하여 환자의 수술 후 활력징후, 활동력과 정신상태, 통증, 오심 구토, 출혈, 식이 및 배뇨 등의 환자상태를 조사하였다. 당일수술에 대한 인지도는 52.7%이었으며, 당일수술 의향이 있는 환자는 52.1%이었다. 당일수술을 받고 싶은 이유로는 "질병이 경미하고 수술이 간단하여"가 43.1%, "집에서 안정을 취해도 충분하므로"가 30.4%이었고, 당일수술을 받고 싶지 않는 이유는 "집에 있기 불안해서"가 56.5%로 가장 높았다. 당일수술 후 가장 염려되는 것은 응급 상황발생에 대한 것이었다. 당일수술의 가장 큰 장점은 입원기간 절약(39.1%)이었으며 단점은 응급상황 시 불안하다는 것이 53.9%로 가장 많았다. 환자의 주관적 판단에 의한 퇴원시기는 수술 후 1-2일이라고 생각하는 사람이 47.6%로 가장 많았다. 수술명에 따른 평균 재원일수는 백내장적출술 2.9일, 사시 교정술 2.2일, 편도선제거술 3일, 탈장교정술 3.8일, 안검복원술 2.2일, 담석증복강경술 4.9일, 치질제거술 4.1일, 치루제거술 4.6일로, 이들 전체의 평균 재원일수는 3.1일이었다. 수술 후 나타난 증상으로는 통증이 45.6%로 가장 많았고, 다음으로 오심 구토(10.5%) 및 두통(7.9%)의 순이었다. 시간대별 퇴원 가능 환자 수는 3시간대에 95.2%, 12시간대에 99.2%, 24시간대에는 100%로 나타나 이 연구에서 선정된 모든 수술이 마취 후 퇴원점수체계에 의한 24시간 이내 퇴원 기준을 충족시켰고, 통상적으로 당일수술 3시간 뒤에 환자가 퇴원하는 것을 고려하면 의학적인 측면에서 당일수술이 가능한 수술은 백내장적출술과 사시교정술로 판단되었다. 당일수술의 경과에 대한 설명과 수술 시행 후에 환자들에게 발생할지도 모르는 응급상황에 대한 대처 방안이 잘 강구 된다면 당일수술의 수요가 증가할 것이며, 그 서비스에 대한 만족도도 높아져 당일수술이 활성화될 것이다.

• 대한골관절종양학회지
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• 제13권1호
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• pp.48-54
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• 2007

목적: 대퇴골 근위부의 광범위 골 파괴를 보이는, 전이성 골 종양에 의한 병적 골절 환자들을 대상으로 종양 대치물 삽입술 시행 후 임상 결과를 알아보고자 하였다. 대상 및 방법: 2005년 10월부터 2006년 10월까지 전이성 골 종양에 의한 병적 골절로 진단 받은 환자 중 대퇴골 근위부에 광범위 전이를 보여 근위부 절제술 및 종양 대치물 삽입술을 시행한 6예를 대상으로 하였다. 평균 연령은 61세(범위, 48~77)였으며 평균 추시 기간은 10.5개월(범위, 6~16)이었다. 원발 종양으로는 다발성 골수종이 2예, 폐암이 1예, 유방암이 1예, 신장암이 1예, 원발 종양을 확인할 수 없었던 경우가 1예였다. 6예 모두에서 $MUTARS^{(R)}$ proximal femur system (Implantcast, Munster, Germany)를 이용하여 재건을 시행하였다. 하지 기능평가에는 Musculoskeletal Tumor Society 1993 score를 사용하였으며, 수술 전 후 동통의 정도를 Visual Analogue Scales (VAS)로 평가하였다. 결과: 최종 추시 시에 모든 환자들이 생존하였으며 하지 기능 점수는 평균 17.8(59.3%)점(범위, 12~25)이었다. VAS는 수술 전 평균 8.5에서 수술 후 최종 추시 시 평균 2.5로 호전되었다. 수술 후 가능한 한 조기 보행을 독려하여 수술 후 평균 7.3일(범위, 3~16)에 보행이 가능하였다. 수술 후 삽입물 주위 골절, 치환물의 해리 또는 감염은 없었으며, 1예에서 수술 후 재발성 탈구가 발생하였다. 결론: 전이성 골 종양의 대퇴골 근위부 광범위 침범 소견이 있는 병적 골절 환자에서 종양 대치물 삽입술은 조기에 동통의 경감 및 하지 기능 회복을 기대할 수 있으면서도 수술 후 합병증 발생이 적어 상대적으로 안전한 술식으로 전이성 골 종양의 치료 취지에 부합되는 적절한 치료로 생각된다.

• 대한한방내과학회지
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• 제37권4호
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• pp.624-630
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• 2016

Objective: This study was designed to analyze the symptoms of chronic obstructive pulmonary disease (COPD) patients who attended a Korean medicine hospital and treatment effects through retrospective chart reviews.Methods: The medical records of 192 outpatients who had been diagnosed with COPD and visited the Allergy, Immune, and Respiratory System Department of Kyung Hee Korean Medicine Hospital from 1 February 2006 to 1 February, 2016 were retrospectively reviewed.Results: The study group consisted of 112 and 80 females. The median age of the patients was 59.80±15.46 y. Fifty of the patients had been diagnosed with chronic upper respiratory diseases, such as chronic rhinitis, nasopharyngitis, or sinusitis. The chief complaints were cough (n=136), sputum (n=124), and dyspnea (n=82). Other frequent symptoms were fatigue (n=11), hyperhidrosis (n=8), and a bad taste in the mouth (n=7). All the patients were prescribed Korean herbal medicine. In the study, 61 (31.77%) patients were treated with acupuncture, moxibustion, cupping therapy, or herbal steam therapy. Symptoms improved in 126 (65.63%) patients 141±272.82 d after the first treatment.Conclusions: Some of the COPD patients had chronic upper respiratory disease. The chief complains were cough, sputum, and dyspnea. Oher frequent symptoms related to body malfunction and pain. The symptoms improved in 126 (65.63%) patients 141.00±272.82 d post-treatment.

• 대한물리치료과학회지
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• 제14권1_4호
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• pp.61-69
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• 2007

Physiotherapy may be defined as the use of physical techniques for the treatment of injuries and movement dysfunction. In the world of human medicine, physiotherapy has been proven as an indispensable aid in the recovery of many musculoskeletal conditions, as evidenced by the extensive physiotherapy departments within most hospitals. Nowadays, this important branch of medicine is also rapidly becoming a recognised tool in the prevention, cure, and rehabilitation of many equine, canine and feline injuries. In 1978, canine physical therapy techniques were described by Ann Downer, a physical therapist on faculty at Ohio State University. Animal physical therapy is a new and rapidly developing field of health care for animals. The benefits of physical therapy have long been recognized in humans. More recently, work in the veterinary field has shown the same benefits of physical therapy to be true for animal patients. Performing orthopaedic or neurological surgery, or fitting a human patient with a cast or splint, and then discharging the patient is an outdated approach. In such cases, physical therapy is clearly warranted. Similarly, recent research has shown that post-surgical rehabilitation and therapy after injuries significantly improves the functional outcomes for animals. The goals of physiotherapy are to relieve pain, restore range of motion/movement, improve function, prevent injuries and expand the physical potential of the patient. Once in the field, physical therapists actively continue their education to keep up to date on the latest treatments and technologies. Via continuing education courses, physiotherapists can learn how to apply their unique and specialized knowledge to other animal species.

• Journal of Acupuncture Research
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• 제26권6호
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• pp.161-169
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• 2009

Objectives : This study was to investigate the correlation of subjective stress caused by traffic accident with patient's prognosis. Methods : We investigated 53 cases of in-patient with traffic accident. The patients answered that questionnaire about subjective pain and stress on hospitalization day and leaving hospital day. And we calculated statistically signification with this data. Results 1. IES-R-K score of female group was significantly higher than male group's. 2. There was statistically significant correlation between IES-R-K score and admission duration. 3. After hospitalization treatment, there was statistically significant reduction of VAS and IES-R-K score. Conclusions : There was significant correlation between subjective stress and prognosis.

• Journal of Dental Anesthesia and Pain Medicine
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• 제19권6호
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• pp.369-378
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• 2019

Background: Behavior guidance is a technique used to subdue inappropriate behavior by establishing communication that meets the needs of a child. This study aimed to measure the effectiveness of a mobile app (Little Lovely Dentist) compared to the tell-show-do (TSD) technique in managing anxious children during their first dental visit. Methods: Fifty children (30 boys and 20 girls) without any past dental experience, aged from 7 to 11 years, were randomly allocated into either the dental app group or the TSD group. The pre- and post-operative anxiety of children who underwent prophylactic cleaning was assessed both physiologically and subjectively using a heart rate measurement and the RMS pictorial scale, respectively. Results: The intragroup comparison of heart rate and RMS scores for children allocated to the dental app group was statistically significant (P value ≤ 0.001). However, a significant reduction only occurred in the RMS scores, but not the heart rate measurements, in the TSD group. Conversely, there was an increase in heart rates in the TSD group. Conclusion: Educating the child prior to a dental procedure using a smartphone application such as Little Lovely Dentist can significantly alleviate the anticipatory anxiety and engage children in dental treatment during their first visit.

• 대한한방내과학회지
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• 제35권3호
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• pp.366-372
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• 2014

Objectives: This is a report of a case of a stage IV non-small-cell lung cancer (NSCLC) patient whose malignant pleural effusion & respiratory symptoms have been relieved with Korean medicinal prescription, modified Yieum-jeon. Methods: A 56-year-old male diagnosed with stage IV NSCLC suffering malignant pleural effusion with complaints of cough, sputum, bilateral leg edema, dysphagia, post neck and left scapular pain was treated with modified Yieum-jeon and acupuncture during 16days. After treatment, blood lab and chest X-ray were used to follow the condition of malignant pleural effusion & pulmonary symptoms. Results: Malignant pleural effusion and pulmonary symptoms were improved with modified Yieum-jeon intake without any related adverse side effects. Conclusions: This study suggests Yieum-jeon may play a positive role in improving the malignant pleural effusion symptoms in advanced lung cancer cases.

• Journal of Korean Neurosurgical Society
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• 제58권3호
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• pp.271-275
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• 2015

Objective : This study was designed to evaluation the diagnostic value of procalcitonin (PCT) in patients with spinal infection, compare to the classical biomarkers such as C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), white blood cell (WBC) count. Methods : All patients who were diagnosed as a spinal infection between January, 2013 and July, 2014 were included in this study. Serum PCT, CRP, ESR, and WBC count were checked at initial hospital visit and once a week serially until they were discharged. Patient's medical history, causes and pathogens of spinal infection were reviewed. Results : Total 34 (16 men, 18 women) patients were included in this study. Mean age of the patients was 65.6 year-old. Causes of spinal infection were pain block procedure (14, 41.2%) and post-operation (5, 14.7%). Out of 25 patients who showed elevated initial serum PCT level, 20 patients (80%) had a combined systemic infection. 14 patients (6.7%) had a sepsis, 3 patients (14.2%) had a urinary tract infection and 2 (9.6%) had a pneumonia. 14 patients (41.2%) showed elevation of serum PCT level during treatment. Among them, 9 patients (64.3%) had a combined infection such as sepsis and urinary tract infection. Conclusion : Serum CRP showed more sensitivity compared to serum PCT in patients with spinal infection. Patients with spinal infection who showed elevated serum PCT level should be investigated for combined infection and proper antibiotics should be applied.