• 한국화재소방학회논문지
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• 제24권4호
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• pp.79-85
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• 2010

본 연구는 공상 소방공무원에 관한 직무스트레스에 관하여 조사 연구하여 소방공무원의 안전보건을 향상시킬 수 있는 기본 자료를 제공하기 위하여 수행되었으며, 연구결과는 다음과 같다. 공상 소방공무원의 직무스트레스는 일반 소방공무원에 비하여 상당히 높으며, 각 세부항목에서는 보상부적절, 조직체계, 직장 문화, 직무불안정에 대하여 상대적으로 스트레스를 더 느끼는 것으로 나타났으며, 한국남자평균에 비하여는 물리적환경, 직장문화에 대하여 상대적으로 스트레스가 높은 것으로 나타났다. 공상 소방공무원의 외상후 스트레스 장애(PTSD)를 한국판 사건충격척도(IES-R-K)로 측정한 결과 조사대상의 75%(30명)가 장애를 느끼는 것으로 나타났다.

• The Korean Journal of Physiology and Pharmacology
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• 제27권1호
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• pp.113-125
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• 2023

It has been reported that stressful events in early life influence behavior in adulthood and are associated with different psychiatric disorders, such as major depression, post-traumatic stress disorder, bipolar disorder, and anxiety disorder. Maternal separation (MS) is a representative animal model for reproducing childhood stress. It is used as an animal model for depression, and has well-known effects, such as increasing anxiety behavior and causing abnormalities in the hypothalamic-pituitary-adrenal (HPA) axis. This study investigated the effect of MS on anxiety or aggression-like behavior and the number of GABAergic neurons in the hippocampus. Mice were separated from their dams for four hours per day for 19 d from postnatal day two. Elevated plus maze (EPM) test, resident-intruder (RI) test, and counted glutamic acid decarboxylase 67 (GAD67) or parvalbumin (PV) positive cells in the hippocampus were executed using immunohistochemistry. The maternal segregation group exhibited increased anxiety and aggression in the EPM test and the RI test. GAD67-positive neurons were increased in the hippocampal regions we observed: dentate gyrus (DG), CA3, CA1, subiculum, presubiculum, and parasubiculum. PV-positive neurons were increased in the DG, CA3, presubiculum, and parasubiculum. Consistent with behavioral changes, corticosterone was increased in the MS group, suggesting that the behavioral changes induced by MS were expressed through the effect on the HPA axis. Altogether, MS alters anxiety and aggression levels, possibly through alteration of cytoarchitecture and output of the ventral hippocampus that induces the dysfunction of the HPA axis.

• 한국대기환경학회지
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• 제32권3호
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• pp.237-247
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• 2016

Global climate change is becoming one of the greatest challenges facing humanity. This article proposes a psychological perspective of climate change adaptation. Climate change-related severe adverse weather events may trigger mental health problems, including increased post-traumatic stress disorder (PTSD), depression, anxiety, violence, and even suicide. Forced migration could be considered a coping method for dealing with weather events, but it may also pose a psychological threat. People respond to severe weather events in different ways based on their individual characteristics. Psychological risks from adverse weather events are mediated and moderated by these factors, which are influenced by personal cognition, affect, and motivation. Examinations from a psychological perspective, which have been neglected in the science of climate change thus far, may provide keys to successful adaptation and the prevention of serious psychological problems resulting from the experience of severe weather events. A new prevention strategy has been suggested for coping with climate threats through encouraging attitude change, establishing proactive support systems for vulnerable groups, establishing a PTSD network, and implementing a stress inoculation program.

• 통합자연과학논문집
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• 제11권2호
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• pp.101-106
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• 2018

Corticotropin - releasing hormone receptor 1 (CRHR1) forms an integral part of the pathophysiology of disorders like post-traumatic stress disorder, stress, anxiety, addiction, and depression. Hence it is essential to look for new, potent and structure-specific inhibitors of CRHR1. We have analysed the protein-protein interaction complexes of the CRHR1 receptor with its native ligand CRF and full agonist Sauvagine. The structure of Sauvagine was predicted using homology modelling. We have identified that the residues TYR253, ASP254, GLU256, GLY265, ARG1014 and LY1060 are important in the formation of protein-protein complex formation. Future studies on these residues could throw light on the crucial structural features required for the formation of CRHR1-inhibitor complex and in studies that try to solve the structural complexities of CRHR1.

• 통합자연과학논문집
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• 제11권1호
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• pp.19-24
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• 2018

CRFR is involved in the pathophysiology of various disorders including depression, stress, anxiety, post-traumatic stress disorder, and addiction. The discovery of novel and structurally diverse CRF1 receptor inhibitors becomes essential. In this study, we have performed molecular docking of CRF1R with the derivatives of 8-substituted-2-aryl-5-alkylaminoquinolines as CRF1R inhibitors. The antagonist molecules were optimized and docked into the binding site of the receptor. On analysing the docked complexes we have identified that the residues HIS214, THR215, ARG227, ARG1008, LYS1060 and ASP1061 are important in forming hydrogen bond with the inhibitors. Further studies on these residues could reveal important structural features required for the formation of CRF1R-inhibitor complex and thus in the discovery of novel and potent inhibitors.

• 한국심리학회지 : 문화 및 사회문제
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• 제25권4호
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• pp.325-351
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• 2019

본 연구는 외상 사건을 경험한 국내 성인의 외상 후 스트레스(Post Traumatic Stress Disorder) 증상과 외상 후 성장(Post Traumatic Growth) 양상을 토대로 잠재계층(latent class)을 도출하고, 각 집단 구분에 영향을 미치는 특성을 탐색하며, 집단에 따른 자기파괴적 행동의 차이를 탐색함으로써, 외상 사건을 경험한 개인에 대해 보다 심층적으로 이해하고자 한다. 이를 위해 본 연구에서는 DSM-5 진단기준에 해당하는 외상 사건을 경험한 국내성인 860명을 대상으로 잠재프로파일분석(Latent Profile Analysis)과 R-3STEP 방식을 이용하였다. 집단 예측 변인으로 개인의 인구사회학적 변인(성별, 연령, 최종 학력, 종교유무, 종교활동 정도, 월 평균 소득)과 사회적 고립, 외상 경험 빈도가 포함되었으며, 종속변인으로 자기파괴적 행동(폭식 정도, 비자살적 자해 유무, 음주의 양, 음주 형태, 음주로 인한 정신 사회적 문제)을 포함하였다. 연구결과 집단은 '저PTSD/중 PTG집단', '저 PTSD/고 PTG집단', '고 PTSD/고 PTG집단'으로 분류되었다. 또한 성별, 최종학력, 사회적 고립, 외상 노출 빈도가 집단 예측 변인으로 영향을 미치는 것으로 나타났으며, 폭식 정도, 비자살적 자해 유무, 음주 형태, 음주로 인한 정신사회적인 문제에서 집단 간 차이가 있는 것으로 나타났다. 마지막으로 본 연구의 결과를 바탕으로 논의와 시사점을 제시하였다.

• 대한한방내과학회지
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• 제35권3호
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• pp.383-397
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• 2014

Objectives: The purpose of this study was to report the effect of traditional Korean medical therapy such as acupuncture, electroacupuncture and herbal medicine in taste disorder patients. Methods: We surveyed 5 taste disorder patients visiting the Oral Diseases Clinic in the Kyung Hee University Oriental Medicine Hospital from January, 2014 to June, 2014. Before starting traditional Korean medical therapy such as acupuncture, electroacupuncture and herbal medicine, the subjects were evaluated on severity of discomfort using visual analogue scale (VAS), salivary flow rate (SFR), quality of life about oral health (based on the 14-item Oral Health Impact Profile-14) and qi-stagnation condition (based on the 23-item qi-stagnation Questionnaire). Visual analogue scale was re-evaluated during the treatment period. Results: There was no relationship between diminished SFR and severity of discomfort. Also change or loss of taste did not influence the quality of life about oral health. However, stress which refers to qi-stagnation could be one of the reasons taste disorder occurs. After receiving traditional Korean medical therapy, all 5 patients' visual analogue scale score decreased. Conclusions: Traditional Korean medical therapy may potentially be an option for taste disorder. Further evaluations including pre-post comparison with larger number of cases will be needed in the future.

• 동의신경정신과학회지
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• 제30권3호
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• pp.251-263
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• 2019

Objectives: The purpose of this study was to review the clinical research trends in the treatment of post traumatic stress disorder (PTSD) in Korean medicine (KM). Methods: We searched MEDLINE, CENTRAL, EMBASE, Google Scholar and five Korean databases through May 2019, for studies on KM to treat PTSD. Clinical research that conducted KM treatment of PTSD patients were included. Two researchers independently conducted study selection and data extraction process. Results: Totally, eight studies were included in this review. Types of traumatic events that patients experienced included physical violence/threatening, traffic accidents, sexual violence and personal tragic events. KM interventions performed included acupuncture, moxibustion, herbal medicine, physical therapy, and KM-based psychotherapy. Treatment duration varied from two days to more than five months. Follow-up began at least one week to three months after the end of treatments. It was reported that the major psychological and/or somatic symptoms of PTSD, such as anxiety, depression, insomnia, and musculoskeletal pain, subjectively improved, as well as other objective outcomes: Impact Event Scale-Revised Korean version (IES-R-K), Beck's Depression Inventory (BDI), State-Trait Anxiety Inventory, Hwabyung Symptoms/characters, Electroencephalography (EEG) change, etc. Statistical studies were conducted in three studies only. Outcomes such as Visual Analogue Scale (VAS), BDI, and IES-R-K showed statistically significant improvement after KM treatments. There was no study reporting adverse events during or after the interventions. Conclusions: According to this review, diverse types of KM treatments have been used among PTSD patients in eight studies. The KM treatments effectively improved psychological and somatic symptoms of PTSD patients. However, the lack of high quality research as well as the lack of standardization of KM treatments for PTSD are limitations. Further methodologically robust clinical trials should be performed, and the standardization of KM treatments for PTSD should be sought.

• 한국화재소방학회논문지
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• 제34권3호
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• pp.126-133
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• 2020

본 연구는 소방공무원의 무조건적 자기수용과 자기노출이 외상 후 성장에 미치는 영향을 알아봄으로써 외상 후 스트레스 장애 등 병리적 결과에 머물지 않고 이전 수준을 뛰어넘는 외상 후 성장을 이룰 수 있는 프로그램 개발 등에 도움을 주고자 하였다. 이를 위해 무조건적 자기수용, 자기노출, 한국판 외상 후 성장 척도 등을 활용하였으며, 연구결과는 다음과 같다. 첫째, 소방공무원의 무조건적 자기수용, 자기노출이 외상 후 성장과 상관관계가 있음이 확인되었다. 둘째, 소방공무원의 무조건적 자기수용과 자기노출 변인 중 외상 후 성장에 미치는 상대적 영향력을 알아보기 위해 위계적 회귀분석을 실시한 결과, 무조건적 자기수용이 자기노출 보다 더 많은 영향을 주는 것으로 확인되었다. 본 연구결과를 토대로 소방공무원 외상 후 성장을 촉진시키는 프로그램 개발 방향 및 치료적 개입 전략 등을 제안하였다.

• 한국산학기술학회논문지
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• 제14권5호
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• pp.2225-2233
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• 2013

본 연구는 외상후스트레스 고위험군이 많이 분포된 구조대원에 대한 사건충격정도를 파악하고, 사건충격정도에 영향을 미치는 관련 요인을 분석하였다. 연구대상은 화재 및 구조출동 빈도가 높은 서울소방재난본부 소속 구조대원 415명을 통계분석 자료로 활용하였으며, 사건충격정도에 대한 신뢰도는 .975로 높게 나타났다. 분석결과 첫째, 사건충격정도의 하위요인으로 침습이 가장 높았고, 회피, 수면장애 및 정서적마비, 해리증상, 과각성 순으로 사건충격정도가 높게 나타났다. 둘째, 기혼자와 연령이 높을수록 사건충격정도가 높았으며, 셋째, 소방공무원으로서 근무연수와 구조대원 직무를 수행한 기간이 길고, 출동횟수와 사고현장 경험빈도가 높을수록 충격정도가 높게 나타났다. 특히 스트레스 해소 방법 중 음주로 해소하는 구조대원의 사건충격정도가 높게 나타나, 고위험군에 대한 체계적인 관리와 사건충격을 경험하였을 때 즉시 대처할 수 있는 예방케어프로그램 도입이 시급한 것으로 나타났다.