• Title/Summary/Keyword: Positive Experience

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Clinical experience with $^{18}F$-fluorodeoxyglucose positron emission tomography and $^{123}I$-metaiodobenzylguanine scintigraphy in pediatric neuroblastoma: complementary roles in follow-up of patients

  • Gil, Tae Young;Lee, Do Kyung;Lee, Jung Min;Yoo, Eun Sun;Ryu, Kyung-Ha
    • Clinical and Experimental Pediatrics
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    • v.57 no.6
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    • pp.278-286
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    • 2014
  • Purpose: To evaluate the potential utility of $^{123}I$-metaiodobenzylguanine ($^{123}I$-MIBG) scintigraphy and $^{18}F$-fluorodeoxyglucose ($^{18}F$-FDG) positron emission tomography (PET) for the detection of primary and metastatic lesions in pediatric neuroblastoma (NBL) patients, and to determine whether $^{18}F$-FDG PET is as beneficial as $^{123}I$-MIBG imaging. Methods: We selected 8 NBL patients with significant residual mass after operation and who had paired $^{123}I$-MIBG and $^{18}F$-FDG PET images that were obtained during the follow-up. We retrospectively reviewed the clinical charts and the findings of 45 paired scans. Results: Both scans correlated relatively well with the disease status as determined by standard imaging modalities during follow-up; the overall concordance rates were 32/45 (71.1%) for primary tumor sites and 33/45 (73.3%) for bone-bone marrow (BM) metastatic sites. In detecting primary tumor sites, $^{123}I$-MIBG might be superior to $^{18}F$-FDG PET. The sensitivity of $^{123}I$-MIBG and $^{18}F$-FDG PET were 96.7% and 70.9%, respectively, and their specificity were 85.7% and 92.8%, respectively. $^{18}F$-FDG PET failed to detect 9 true NBL lesions in 45 follow-up scans (false negative rate, 29%) with positive $^{123}I$-MIBG. For bone-BM metastatic sites, the sensitivity of $^{123}I$-MIBG and $^{18}F$-FDG PET were 72.7% and 81.8%, respectively, and the specificity were 79.1% and 100%, respectively. $^{123}I$-MIBG scan showed higher false positivity (20.8%) than $^{18}F$-FDG PET (0%). Conclusion: $^{123}I$-MIBG is superior for delineating primary tumor sites, and $^{18}F$-FDG PET could aid in discriminating inconclusive findings on bony metastatic NBL. Both scans can be complementarily used to clearly determine discrepancies or inconclusive findings on primary or bone-BM metastatic NBL during follow-up.

An analysis of changing interests in mathematics and strategic thinking reflected in small group drawing activities using graphs and inequations - With Grafeq software - (그래프와 부등식 영역의 소집단 그림그리기 활동에서 나타나는 수학에 대한 흥미변화 및 전략적 사고분석 -Grafeq 활용을 중심으로-)

  • Shin, In-Sun;Park, Kyung-Min
    • Communications of Mathematical Education
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    • v.26 no.2
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    • pp.177-203
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    • 2012
  • The purpose of this research was to look at whether small group drawing activities can be applied to learning content that combine mathematics and art, by analyzing the changes in $10^{th}$ grade students' interests in mathematics and particular features of their strategic thinking that were reflected in small group drawing activities using graphs and inequations. The results of the study are as follows: 1. The small group drawing activity using graphs and inequations demonstrated that students interests in mathematics could experience positive changes. 2. The small group drawing activity using graphs and inequations was effective in stimulating the students' strategic thinking skills, which are higher level thinking activities necessary for creating problem solving. As the students went through the whole process of accomplishing a complete goal, the students engaged in integrated thinking activities that brought understandings of basic graphs and inequations together, and were also found to use such higher level thinking functions needed in achieving creative problem solving such as critical thinking, flexible thinking, development-oriented thinking, and inferential thinking. 3. The small group drawing activity using graphs and in equations could be expected to constitute learning content that integrate mathematics and art, and is an effective solution in boosting students' strengths in mathematics by way of activities that consider students' unique cognitive and qualitative peculiarities and through integration with art.

The Impact of Cognitive Factors of IS Security Risk Management(ISM) on Awareness and Intention to Develop ISM (보안관리 인지 요인이 조직의 정보시스템 보안위험관리에 대한 인식 및 개발의지에 미치는 영향)

  • Kim, Sanghyun;Song, Youngmi
    • Information Systems Review
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    • v.14 no.2
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    • pp.21-46
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    • 2012
  • Organizations that make widely use of information technologies can be more efficient. But, the dependence of information technologies leads to an increase in threat of security. This is the reason why organizations are investing in security risk management (SRM) which is designed to protect of information assets. Noting a lack of empirical research in SRM, we investigate the key factors having a direct effect on performance of SRM. Particularly, this study focused on identifying factors influencing awareness of SRM and Intention to develop SRM in Organization. Based on relevant literature review, six motivating factors, including Behavior for Security Management, Compliance with Security Policy, perceived Benefits, Perceived Sacrifice, Social Pressure, Experience of Security Risks, were initially identified. The results indicated that most perception factors were positively related to Organization's intention to develop SRM and awareness of SRM, which then had positive impact on performance of SRM. But Perceived Sacrifice was not significantly related to two variables which is Organization's intention to develop SRM and awareness of SRM.

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Factors influencing weight control behavior and intention of obese children and adolescents (비만아동 및 청소년의 체중조절 경험과 비만관리 의도에 영향을 미치는 요인)

  • Kang, Yun-Ju;Sohn, Myong-Sei;Jin, Ki-Nam;Kim, Han-Joong;Oh, Hee-Choul;Suh, Sung-Jae
    • Journal of Preventive Medicine and Public Health
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    • v.31 no.2 s.61
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    • pp.199-214
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    • 1998
  • This study was undertaken to explain weight control behavior and intention of obese children and adolescents as measured by the elements of the health belief model. A total of 732 obese students from 28 schools in Seoul metropolitan area and their mothers were assessed with a self-administered questionnaire. The analyzed results are as follows; 1. Among obese students, 45.3% of male students and 57.2% of female students, a significantly higher portion than male students, reported that they had tried to lose weight within the recent year. Exercise was the most frequently used method to lose weight followed by diet control, drug use, and specialized clinic visits, in descending order. 2. Male students were more likely to try to lose weight if they perceived a low threat level and their mother had a job, and female students were more likely to try to lose weight if they were younger in age, perceived a low threat level and had strong external motivating factors. 3. Female students showed a significantly higher level of intention to obesity control than male students, and the intention level of their mothers also showed the same trend. 4. In male students, the degree of weight dissatisfaction, weight control experience, the level of obesity related beliefs of students, the educational level of the mother and economic status of the family were significant predictors of intention to obesity control, and in females, age, the level of obesity related beliefs of students and intention of their mothers were significant. In the mothers of male students, obesity index of students, age of the mother and the level of obesity related beliefs of the mother were significant predictors of intention of the mother, and in the mothers of female students, obesity index of students, occupational status of the mother and obesity related beliefs of the mother were significant. 5. According to the path model of intention to obesity control, the degree of weight dissatisfaction had the most powerful effect in male students, and perceived net benefit level was the most important variable in female students. Since the weight control behavior and intention of obese students were more predictable by the degree of weight dissatisfaction than the obesity index, we can conclude that only the students dissatisfied with their weight are well motivated for obesity control. There can be a discrepancy between the mother and her child's beliefs and intention status(especially in male students), so the therapists should also assess the student's opinion as well as the mother's. In female students, the perceived net benefit level wag the most important predictor of intention to obesity control, therefore the intervention program should pay particular attention to the positive benefits of weight control rather than negative aspects(threats) of obesity.

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Self-administration of an Analgesic Does Not Alleviate Pain in Beak Trimmed Chickens

  • Freire, Rafael;Glatz, Philip C.;Hinch, Geoff
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.3
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    • pp.443-448
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    • 2008
  • Beak trimming in laying hens is a routine practice in which about 1/3-1/2 of the upper and lower beak is removed with the aim of reducing cannibalism. This experiment aimed to identify if this procedure causes pain by examining self-administration of an analgesic (carprofen) and pecking behaviour in 80 laying pullets beak-trimmed by two different methods at one day of age using hot-blade cauterisation or infra-red cauterisation. We also tested a control treatment, pullets with intact beaks, and a positive control treatment of pullets beak trimmed at 10 weeks of age which were expected to experience some pain due to recent severing of the underlying nerves in the beak. At 11 weeks of age birds trimmed at 10 weeks of age pecked more (p<0.001) gently ($0.6{\pm}0.06N$) at a disc attached to a force-displacement transducer than birds trimmed at 1 day of age with an infra-red machine ($0.9{\pm}0.1N$) or a hot blade ($1.1{\pm}0.07N$) and intact birds ($1.2{\pm}0.1N$). Maximum force of pecks recorded was also lower (p<0.001) in birds trimmed at 10 weeks of age than birds trimmed at 1 day of age with an infra-red method or a hot blade and intact birds. However, the pecking force in birds trimmed at 10 weeks of age was not increased by providing them with analgesic-treated feed, though birds that ate more carprofen had a higher maximum force of peck (p = 0.03). Pecking force in birds beak-trimmed at 1 day of age was the same as the pecking force of intact birds, and was unaffected by feeding pullets carprofen. A method of self-administration of an analgesic had previously revealed that chickens in neuromuscular pain arising from lameness consumed more of a feed containing carprofen than healthy chickens. However, we found no evidence that beak-trimmed pullets consumed more carprofen-treated feed than pullets with an intact beak. It should be noted that the three beak trimming methods resulted in an average 34% reduction in beak length, considered a light trim, and is perhaps not representative of commercial birds where greater portions of the beak are removed. We conclude that although carprofen has been reported to have an analgesic effect on neuromuscular pain in chickens, it appears to have no analgesic effect on potential neuropathic pain arising from the nerves severed by a light beak trim.

DNA Ploidy and S-phase Fraction Analysis in Paediatric B-cell Acute Lymphoblastic Leukemia Cases: a Tertiary Care Centre Experience

  • Kumar, Banothu Kiran;Bhatia, Prateek;Trehan, Amita;Singh, Ajit Pal;Kaul, Deepak;Bansal, Deepak
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.17
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    • pp.7917-7922
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    • 2015
  • DNA ploidy is an important prognostic parameter in paediatric B-ALL, but the significance of the S-phase fraction is unclear. In present study, DNA ploidy was assessed in 40 pediatric B-ALL cases by flow cytometry. The DI (DNA index) and percentage of cells in S-phase were calculated using Modfit software. Aneuploidy was noted in 26/40 (65%) cases. A DI of 1.10-1.6 (hyperdiploidy B) was noted in 20/40 (50%) and 6/40 (15%) had a DI>1.60 (triploid and tetraploid range). Some 14/40 (35%) cases had a diploid DI between 0.90-1.05. None of the cases had a DI <0.90 (hypodiploid) or in the 1.06-1.09 (hyperdiploid A) range. The mean S-phase fraction was 2.6%, with 24/40 (60%) having low and 16/40 (40%) high S-phase fractions. No correlation was noted with standard ALL risk and treatment response factors with DI values or S-phase data, except for a positive correlation of low S-phase with high NCI risk category (p=0.032). Overall frequency of hyperdiploidy in our cohort of B-ALL patients was very high (65%). No correlation between hyperdiploidy B and low TLC or common B-phenotype was observed in our study as 42% cases with DI 1.10-1.6 had TLC> $50{\times}10^9$ and 57.1% CD 10 negativity. The study also highlighted that S-phase fraction analysis does not add any prognostic information and is not a useful parameter for assessment in ALL cases. However, larger studies with long term outcome analysis are needed to derive definitive conclusions.

A Study on the Satisfaction and Achievement of Learning by Female Learner's Characteristics in Internet Education Program (여성 학습자의 특성에 따른 인터넷교육 프로그램 만족도와 학업성취도에 관한 연구)

  • Lim, Kwang Myung;Kim, Sung Soo
    • Journal of Agricultural Extension & Community Development
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    • v.8 no.1
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    • pp.25-40
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    • 2001
  • The purposes of the study were to identify satisfaction and achievement of learning by female learner's characteristics, and to suggest measures to improve quality of education in internet education programs. In order to determine the educational effectiveness associated with the characteristics of learners, this study attempted to employ two way approaches by observing the degree of achievement for learning, which represents an instructor-oriented approach, and the degree of satisfaction for education, which represents a learner-oriented approach to enhance the quality of internet education for female learners. As an approach to evaluate the educational effectiveness, the degree of achievement in learning(Tyler's classical approach), and the degree of satisfaction for education (Scriven's consumer-oriented evaluation model) were utilized. A survey form was developed by the researcher after reviewing the various tools originated from Boshier, Cross, Gagne and Choi, and distributed to a panel of judges that examined the content validity of the instrument. The sample for the study consisted of 160 female learners from three universities in Seoul and capital area, and the survey form was used to collect data for this study. The SPSS WIN program was used in analyzing the data and a series of statistical tests were conducted including frequency, percentile, t-test, ANOVA, correlation, multiple regression, and factor analysis. The statistical significance level was 0.05. The following conclusion were drawn from this study of female internet education. First, it was evident that female internet learners tend to utilize information from internet, and this can be interpreted as participants' positive attitude, and voluntary participation. Second, educational facilities and services should be improved in the future, because the level of satisfaction was low in these areas compared to curriculum and educational methodology. Third, the participating factors influenced by the level of satisfaction for education of learner characteristics were the 'formation of inter-personal relationship and willingness to change' and the 'needs for education on internet', thus appeared that both social and educational needs influenced the level of satisfaction for education. Fourth, the degree of achievement in learning was higher in the order of 1) attitude 2) function 3) knowledge, thus, attitude change was the most important in achievement of learning. Fifth, the individual background that influenced the level of achievement in learning were age and educational experience. As for the individual level of achievement for learning, the younger and more educated group were more satisfied.

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A STUDY ON CORMORBID PSYCHOPATHOLOGY AND PARENTING ATTITUDE IN CHILDREN AND ADOLESCENTS WITH ATOPIC DERMATITIS (아토피피부염 소아 청소년에서의 정신병리와 양육태도 연구)

  • Jung, Jae-Suk;Kim, Kyu-Han;Hong, Kang-E
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.10 no.1
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    • pp.34-42
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    • 1999
  • The purpose of this study was to examine the nature of psychopathology and psychosocial environments of children with Atopic Dermatitis(AD) and their relationship to skin symptoms. Seventy outpatients with AD(mean age 9.94, range 4-15 years) and their mothers were subjected to psychiatric interview and parent- and self-report questionnaire(CBCL, MBRI, CDI, Spielberger's State-Trait Anxiety Inventory for Children(STAI), Family Impact questionnaire). Disease severity was assessed in three dimensions(skin extent, disease activity, and subjective symptom) by SCORAD index. Sixteen(22.9%) of our sample were suspected to have behavioral-emotional problems and they were different from non-problem group on depression, trait-anxiety, maternal controlling attitude and negative appraisal of children. While skin inflammation activity was correlated with only trait-anxiety and depression, subjective skin symptoms were correlated with many psychosocial factors such as depression, state-and traitanxiety, family-impact, social competence, internalized and externalized behavioral problem, sexual problem, and mother's positive appraisal of children). We concluded that children with AD are highrisk group for behavioral-emotional problems, and these problems along with maternal negative parenting attitude can affect their subjective symptom experience.

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A Study on Pre-Service Teachers' Perceptions about the Image of Childcare Center Teachers and Self-image (예비보육교사의 보육교사 이미지에 대한 인식과 자아이미지 탐색연구)

  • Yang, Hea young
    • Korean Journal of Child Education & Care
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    • v.18 no.2
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    • pp.147-165
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    • 2018
  • The purpose of this study was to investigate how to develop of pre-service childcare teachers' perception about the image of childcare center teachers and self-image. In this study, participants' self-analysis method and in-depth interview were adopted to analyze the aspects of pre-service teachers' teacher image. Also, the narrative of pre-service teachers' a famous painting analysis were reported. The results of this study were divided into nine categories. Findings indicated that participants' self-image analysis work made pre-service teachers more enabled them to expend the significance of teacher's image of role in relation to their career decision and future their teacher's job. Moreover, through the experience of self-analysis work the pre-service teachers recognize their own ability to build up unique and healthy image. To foster the ability of pre-service teachers' self- image, special class teaching methods for pre-service teachers should be developed focusing on evoking them to have more positive self-image. This study suggested that self-image analysis work experiences should be emphasized in university class for pre-service teachers.

The Influence of Practice Teaching Utilizing Content Representation on the Development of Student Teachers’ Pedagogical Content Knowledge (CoRe를 활용한 교육실습이 예비 교사들의 PCK 개발에 미치는 영향)

  • Jeong, Yoojeong;Lee, Kyunghee;Choi, Byungsoon
    • Journal of the Korean Chemical Society
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    • v.59 no.6
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    • pp.520-532
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    • 2015
  • The purposes of this study were to examine what kinds of educational activities were carried out during the practice teaching based on CoRe and to identify the role of CoRe and its influence on the development of expertise of student teachers. This study was performed as qualitative case study. The subjects of this study were one practice supervisor teacher and two student teachers. Data were collected through recording CoRe discussion process, student teachers' instructional scene, and semi-constructed interview, and analyzed by an inductive method. Student teachers noticed their own misconceptions, and clarified the concepts based on CoRe during the discussion with supervisor teacher. They also supplemented their lack of knowledge and made up new strategies through the process of sharing their ideas. During the discussion, the supervisor teacher conveyed his teaching experience based on his own orientations toward science teaching. In this course, CoRe plays roles as follows. Firstly, CoRe played a role as guiding supervisor teacher's coaching process. Secondly, CoRe helped for the supervisor teacher to recognize their own PCK. Thirdly, CoRe served as a tool of helping their communication. In turn CoRe proved to be a useful frame for teaching student teachers during practice teaching. Student teachers were provided with a useful framework for preparing lessons by developing CoRe for the topic they teach. Developing CoRe with supervisor teacher at the planning stage of lessons enhenced student-teachers' subject matter knowledge and their PCK including knowledge of science curricula and knowledge of student's understanding of science. Also student teachers understood the components of PCK and experienced the positive understanding toward students, teaching activities, and themselves as a science teacher.