• Journal of Preventive Medicine and Public Health
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• v.19 no.1 s.19
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• pp.123-129
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• 1986

Fetal weight data from 84 litters of Sprague-Dawley rats were statistically analyzed for the effect of position in the uterine horn on fetal weight. The standard score obtained from the mean weight and standard deviation of all fetuses in a uterine horn were studied for position effect. In control group, the heaviest fetus occupied the middle position with a progressive decrease in weights toward the ovarian and cervical ends of the horn. But the effect related to position for the fetal weight was not statistically significant. In contrast, rats acutely or chronically exposed to carbon monoxide showed statistically significant positional differences of fetal weight within the uterine horns. The findings that the intrauterine position effect on fetal weight which is not signicant in control group may act one of confounders at the situation of transplacental toxicological studios.

• Phonetics and Speech Sciences
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• v.4 no.2
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• pp.61-70
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• 2012

The current study observes the durational interaction of tautosyllabic consonants and vowels in the word-initial position of English and Korean child-directed speech (CDS). The effect of phonological laryngeal contrasts in stops on the following vowel duration, and the effect of the intrinsic vowel duration on the release duration of preceding stops in addition to the acoustic realization of the contrastive segments are explored in different prosodic contexts - phrase-initial/medial, focal accented/non-focused - in a marked speech style of CDS. A trade-off relationship between Voice Onset Time (VOT), as consonant release duration, and voicing phonation time, as vowel duration, reported from adult-to-adult speech, and patterns of durational variability are investigated in CDS of two languages with different linguistic rhythms, under systematically controlled prosodic contexts. Speech data were collected from four native English mothers and four native Korean mothers who were talking to their one-word staged infants. In addition to the acoustic measurements, the transformed delta measure is employed as a variability index of individual tokens. Results confirm the durational correlation between prevocalic consonants and following vowels. The interaction is revealed in a compensatory pattern such as longer VOTs followed by shorter vowel durations in both languages. An asymmetry is found in CV interaction in that the effect of consonant on vowel duration is greater than the VOT differences induced by the vowel. Prosodic effects are found such that the acoustic difference is enhanced between the contrastive segments under focal accent, supporting the paradigmatic strengthening effect. Positional variation, however, does not show any systematic effects on the variations of the measured acoustic quantities. Overall vowel duration and syllable duration are longer in English tokens but involve less variability across the prosodic variations. The constancy of syllable duration, therefore, is not found to be more strongly sustained in Korean CDS. The stylistic variation is discussed in relation to the listener under linguistic development in CDS.

• Journal of Nutrition and Health
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• v.36 no.3
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• pp.270-279
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• 2003

Conjugated linoleic acid (CLA) is a group of positional and geometric isomers of linoleic acid (LA) and exhibits anticarcinogenic activity in a variety of animal models. We have previously observed that CLA inhibited the growth of Caco-2 cells, a human colon adenocarcinoma cell line. The present study was performed to determine whether the growth inhibitory effect of CLA is related to change in secretion of IGF- II and/or IGF-binding proteins (IGFBPs) that have been shown to regulate Caco-2 cell proliferation by an autocrine mechanism. Cells were incubated in serum-free medium with various concentrations of CLA or linoleic acid (LA). Immunoblot analysis of 24-hours, serum-free, conditioned medium using a monoclonal anti-IGF-IIantibody revealed that Caco-2 cells secreted both mature 6,500 Mr and higher Mr forms of pro IGF-II. The levels of pro IGF-II and mature IGF-IIwere decreased by 43 $\pm$ 2% and 53 $\pm$ 6%, respectively by treatment with 50 $\mu$ M CLA. LA slightly increased pro IGF- II levels. Results from Northern blot analysis showed that CLA decreased IGF-II mRNA levels at 50 $\mu$ M concentration suggesting that CLA regulation of IGF-II protein expression occurs partly at the transcriptional level. Ligand blot analysis of conditioned media using 1251-IGF-II revealed that CLA slightly decreased IGFBP-2 levels and increased IGFBP-4 levels. We confirmed our previous results that CLA inhibited cell growth in a dose-dependent manner but LA slightly increased cell growth. Exogenous IGF-II mitigated the growth inhibitory effect of CLA. These results indicate that the growth inhibitory effect of CLA may be at least in part mediated by decreasing IGF-II and IGFBP-2 secretion and increasing IGFBP-4 secretion in Caco-2 cells.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.10 no.4
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• pp.680-686
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• 2006

Document images captured by scanners have only skewing distortion. But camera captured document images have not only skew but also vignetting effect and geometric distortion. Vignetting effect, which makes the border areas to be darker than the center of the image, make it difficult to separate characters from the document images. But this effect has being decreased, as the lens manufacturing skill is developed. Geometric distortion, occurred by the mismatch of angle and center position between the document image and the camera, make the shape of characters to be distorted, so that the character recognition is more difficult than the case of using scanner. In this paper, we propose a method that can increase the performance of character recognition by correcting the geometric distortion of document images using a linear approximation which changes the quadrilateral region to the rectangle one. The proposed method also determine the quadrilateral transform region automatically, using the alignment of character lines and the skewed angles of characters located in the edges of each character line. Proposed method, therefore, can correct the geometric distortion without getting positional information from camera.

• Journal of KIISE:Software and Applications
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• v.28 no.10
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• pp.699-705
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• 2001

As it became possible to generate 3D sound on a PC environment due to the advances in computing performance and digital signal processing technology, 3D sound technology gains its focus in the multimedia area Specifically a two-channel based 3D sound technology is being studied by many researchers because of its space efficiency and economical structure. While the positional sound effect is simple in its implementation, the moving sound effect has many problems to be resolved as there are only discrete measured point of HRTF database. In this paper, we propose the method of generating smooth moving sound in a two-channel based 3D sound technique with respect to generating smooth trajectory, and the interpolation method of discrete measured HRTF data. We perform the tests in the PC environment and prove the utility of the proposed method.

• Food Science of Animal Resources
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• v.36 no.2
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• pp.170-177
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• 2016

Conjugated linoleic acid (CLA) is a group of positional and geometric isomers of conjugated dienoic derivatives of linoleic acid. CLA has been reported to be able to reduce body fat. In this study, we investigated the antidiabetic effect of fermented milk (FM) containing CLA on type II diabetes db/db mice. Mice were treated with 0.2% low FM, 0.6% high FM, or Glimepiride (GLM) for 6 wk. Our results revealed that the body weight and the levels of fasting blood glucose, serum insulin, and leptin were significantly decreased in FM fed mice compared to db/db mice. Oral glucose tolerance and insulin tolerance were significantly ameliorated in FM fed mice compared to db/db mice. Consistent with these results, the concentrations of serum total cholesterol, triglycerides, and LDL cholesterol were also significantly decreased in FM fed mice compared to db/db mice. However, the concentration of HDL cholesterol was significantly higher in FM fed mice compared to db/db mice. These results were similar to those of GLM, a commercial anti-diabetic drug. Therefore, our results suggest that FM has anti-diabetic effect as a functional food to treat type II diabetes mellitus.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.9
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• pp.1315-1328
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• 2004

Conjugated linoleic acid (CLA) is a mixture of positional and geometric isomers of octadecadienoic acid with two conjugated double bonds. Of more than a dozen isomers of CLA found naturally in dairy and meat products from ruminants, c-9, t-11 and t-10, c-12 are the two isomers with known physiological importance, including anticarcinogenic, antidiabetic, antilipogenic, and antiatherosclerotic effects. Positive effects of CLA on immune function and bone modeling have also been reported. In spite of the compelling findings in tissue cultures and experimental animal models, its effect, dose, and mechanism of action vis-à-vis specific isomers remains speculative. Results obtained from animal models are inconclusive and conflicting at times in humans, where the research data is limited. It appears that there is a long way to go before CLA could be accepted unequivocally as having definite effects in any or all of these physiological states and how such effects actually occur in humans. The objective of this review is to critically examine the available literature on potential health benefits of CLA observed in cell culture, animal models, and human subjects, wherever possible and to a certain extent the mechanism of action associated with these biological activities.

• Proceedings of the Korea Contents Association Conference
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• 2006.11a
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• pp.788-791
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• 2006

The perception of English labial consonants was investigated via experiment where 40 Korean EFL learners identified nonwords with the target labial consonants [p, b, f, v] in 4 different prosodic locations. The results showed that there was a strong positional effect since the accuracy rates of the four target consonants differed by position. Specifically, the average accuracy rate for the target consonants was higher in the stressed intervocalic position and initial onset position than in the unstressed intervocalic position and final coda position. Further, the accuracy rate for [f] is was high in all prosodic locations except the unstressed intervocalic position. This is unexpected in markedness theory given that fricatives are assumed to be more difficult to learn than stops.

• Proceedings of the KSME Conference
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• 2004.11a
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• pp.1586-1591
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• 2004

Flow visualization experiments have been performed to investigate the effects of phase lag, reduced frequency qualitatively by examining wake pattern on a dragonfly type wing. The model was built with a scaled-up, flapping wings, composed of paired wings with fore- and hindwing in tandem, that mimicked the wing form of a dragonfly. The present study was conducted by using the smoke-wire technique, and an electronic device was mounted to find the exact positional angle of wing below the tandem wings, which amplitude is ranged from $-16.5^{\circ}$ to $+22.8^{\circ}$. Phase lag applied on the wings is $0^{\circ}$, $90^{\circ}$, $180^{\circ}$ and $270^{\circ}$. The reduced frequency is 0.15, 0.3 and 0.45 to investigate the effect of reduced frequency. It is inferred through observed wake pattern that the phase lag clearly plays an important role in the wake structures and in the flight efficiency as changing the interaction of wings. The reduced frequency also is closely related to wake pattern and determines flight efficiency.

• Journal of Sensor Science and Technology
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• v.8 no.1
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• pp.80-88
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• 1999

This paper deals with the position determination problem of stereo camera systems used as a sensor for 3D robotic manipulation. Stereo cameras having parallel rays of sight and been set up on the same baseline are assumed. The distance between the sensor and the space measured is determined so as to get insensitive parameters to the uncertainty of control points used for calibration and to satisfy the error condition set by considering the repeatability of the robot. The baseline width is determined by minimizing the mutual effect of 3D positional error and stereo image coordinate error. Unlike existing techniques, the technique proposed here is developed without complicated constraints and modelling process of the object to be observed. Thus, the technique of this paper is more general and its effectiveness is proved by simulation.