• Biomolecules & Therapeutics
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• v.16 no.1
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• pp.1-8
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• 2008

Mitochondria are important sensor of apoptosis. $H_2O_2-induced$ cell death rate was enhanced by serum deprivation. In this study, we investigated whether serum deprivation using 0.5 or 3 % FBS induces apoptotic cell death through mitochondrial enzyme activation as compared to 10 % FBS. Apoptotic cell death was observed by chromosome condensation and the increase of sub-G0/G1 population. Serum deprivation reduced cell growth rate, which was confirmed by the decrease of S-phase population in cell cycle. Serum deprivation significantly increased caspase-9 activity and cytochrome c release from mitochondria into cytosol. Serum deprivation-induced mitochondrial changes were also indicated by the increase of ROS production and the activation of mitochondrial enzyme, succinate dehydrogenase. Mitochondrial enzyme activity increased by serum deprivation was reduced by the treatment with rotenone, mitochondrial electron transport inhibitor. In conclusion, serum deprivation induced mitochondrial apoptotic cell death through the elevation of mitochondrial changes such as ROS production, cytochrome c release and caspase-9 activation. It suggests that drug sensitivity could be enhanced by the increase of mitochondrial enzyme activity in serum-deprived condition.

• Ocean and Polar Research
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• v.34 no.3
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• pp.275-286
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• 2012

Over the last 20 years there have been more than 3000 peer-reviewed papers relating to climate change and biodiversity published, and still the numbers are increasing. However, most studies focused on the impacts of climate change at population or community levels, and the results invariably reveal that there has been, or will be, a negative effect on the structure and pattern of biodiversity. Moreover, the climate change models and statistical analyses used to test the impacts are only newly developed, and the analyses or predictions can often be misled. In this review, I ask why an individual's life history is considered in the study how climate change affects biodiversity, and what ecological factors are impacted by climate change. Using evidence from a range of species, I demonstrate that diverse life history traits, such as early growth rate, migration/foraging behaviour and lifespan, can be shifted by climate change at individual level. Particularly I discuss that the optimal decision under unknown circumstance (climate change) would be the reduction of the ecological fitness at individual level, and hence, a shift in the balance of the ecosystem could be affected without having a critical impact on any one species. To conclude, I summarize the links between climate changes, ecological decision in life history, the revised consequence at individual level, and discuss how the finely-balanced relationship affects biodiversity and population structure.

• Journal of Ecology and Environment
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• v.30 no.1
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• pp.57-62
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• 2007

To obtain demographic information on threatened gold-spotted pond frog (Rana chosenica Okada, 1931) populations, we determined the ages of 45 male and 13 female frogs (20 males and 9 females from Cheongwon and 25 males and 4 females from Tae-an) and compared the age structures and growth patterns of the two populations in 2006. The snout-vent length (SVL) and body weight of female frogs were greater than those of male frogs in both populations. Male frogs' ages ranged 2 to 7 years old and females' ages ranged 3 to 6 years old. In both populations, 4 years old male frogs were the most abundant age-sex class. The age structures of the two populations were significantly different and the growth coefficients of male frogs from the Cheongwon population were greater than those from the Tae-an population. The mean age of males from the Tae-an population was higher than that from the Cheongwon population. However, the SVL and body weights of male frogs were not different between two populations and there was no difference between the two populations in the mean male SVL at any age. The results could increase our understanding of the life-history of this threatened frog and may be useful in conservation planning.

• Journal of Korean Society of Rural Planning
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• v.29 no.4
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• pp.117-125
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• 2023

This study aimed to analyze the recent status and changes in impervious surface areas and their ratios across regions in Gyeongsangnam-do, providing fundamental data for regional development and impervious surface management. Based on the 'Guidelines for Calculating Water Cycle Management Indicators for Nonpoint Pollution Source Control(Ministry of Environment)', we processed the land characteristics survey map(shapefile) from 2018 and 2022 to analyze impervious surface area and their rates by administrative boundaries. The impervious surface area in Gyeongsangnam-do increased from 75,652 ha in 2018 to 81,055 ha in 2022, with the rate rising by 0.51% from 7.18% to 7.69%. The average of impervious surface area across 545 eupmyeon units expanded by approximately 9 ha, from 139.8 ha in 2018 to 148.8 ha in 2022, with the rate increasing by 0.71%. Concurrently, the whole population declined by 2.8% while the number of households surged by 6.4%, correlating with the growth in impervious areas. Despite population decreases, factors such as population migration, increased household fragmentation, new residential developments, and industrial facility expansions have consistently contributed to the rise in impervious surface area. Notably, even in areas with high impervious surface area rate, significant disparities existed between urbanized areas and predominantly rural regions. Furthermore, about 333 units(61% of the whole eupmyeons), showed negligible changes in their impervious surface area rate, with an increase of less than 0.5%.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.9
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• pp.322-328
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• 2016

This study investigated the effects of temperature, salinity, and algal diet to find the optimal conditions for 5 days for the mass culture of the tropical tintinnid, Metacylis tropica. This tintinnid had a small, hyaline, and ovoid lorica. The oral diameter, length, and maximum width of the lorica were $36.7{\mu}m$, $49.5{\mu}m$, and $44.5{\mu}m$, respectively. In the temperature experiments, the highest maximum density and population growth rate were observed at $30^{\circ}C$ with 340.7 cells/mL and 1.1/day, respectively. Lower salinities adversely affected the population growth of M. tropica. The maximum density was observed at 33 ppt (840 cells/mL). In the diet experiments, M. tropica fed Isochrysis galbana showed the highest density (413 cells/mL) and population growth rate (1.2/day). As a result, M. tropica is appropriate as a potential prey organism for early fish larvae with smaller mouths because the tintinnid has a relatively small size compared to the rotifer. In addition, the conditions of $30^{\circ}C$, 33 ppt and supplying I. galbana would be effective in the cultivation of M. tropica.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.4115-4121
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• 2015

Background: Colorectal cancer is the second most common cause of cancer death with half a million deaths per year. Incidence and mortality rates have demonstrated notable changes in Asian and African countries during the last few decades. In this study, we first aimed to determine the trend of colorectal cancer mortality rate in each Institute for Health Metrics and Evaluation (IHME) region, and then re-classify them to find more homogenous classes. Materials and Methods: Our study population consisted of 52 countries of Asia and North Africa in six IHME pre-defined regions for both genders and age-standardized groups from 1990 to 2010.We first applied simple growth models for pre-defined IHME regions to estimate the intercepts and slopes of mortality rate trends. Then, we clustered the 52 described countries using the latent growth mixture modeling approach for classifying them based on their colorectal mortality rates over time. Results: Statistical analysis revealed that males and people in high income Asia pacific and East Asia countries were at greater risk of death from colon and rectum cancer. In addition, South Asia region had the lowest rates of mortality due to this cancer. Simple growth modeling showed that majority of IHME regions had decreasing trend in mortality rate of colorectal cancer. However, re-classification these countries based on their mortality trend using the latent growth mixture model resulted in more homogeneous classes according to colorectal mortality trend. Conclusions: In general, our statistical analyses showed that most Asian and North African countries had upward trend in their colorectal cancer mortality. We therefore urge the health policy makers in these countries to evaluate the causes of growing mortality and study the interventional programs of successful countries in managing the consequences of this cancer.

• Korean Journal of Agricultural Science
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• v.1 no.1
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• pp.91-116
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• 1974

Taiwan agricultural development in the last decade has not been changed much since the accomplishment of land reform program. This is mainly due to the rapid development taken place within industry that agricultural development can not keep pace with. The increasing gap of rural-urban income discrepancy has caused socio-psychological unstability among rural people and inspire wants of out-migration. From 1961 to 1970, population of the ten largest cities showed an annual growth rate of 4.05%, while the population of the remainder of Taiwan showed 2.06%. Assuming the natural increase rate of these two population sections are similar, the difference of rural and urban annual growth rate can be at tributed to the flow of people from rural to urban sectors. The main objective of this paper is to identify the amount of agricultural out-migration and its impact on agricultural development and agricultural extension programs. Specifically, the objectives are to examine (1) rural-urban population composition (2) rural out-migration estimation (3) changes of agricultural population, and (4) implications for agricultural development and extension programs Some of the important findings are listed below; (1) The average agricultural out migration of the period 1960-1969 is estimated at around 60,000 per year. Take Tainan prefecture for example, the Male-Female Migration Ratio is 0.39 for age 20-24, 0.55 for age 25-29, 0.90 for 30-34. It is understood between age 20 and 34, the rural female migration rate is higher than the rural male. (2) Based on the population growth rate of 1950-1969, agricultural population is projected for the period of 1953 to 1989. By 1978, the agricultural population will reach its peak and begin to dedaine from 1980. The projected agricultural population in 1989 is 5,847,566 which occupies 29% of the Taiwan total population. (3) Assuming area of cultivated land keep unchanged as 905,263 ha. in 1970, and tif we can eliminate all 72% of part-time farms, then the average farm acreage for hose full-time farms will be increased to 3.6 hactares. This is unlikely to happen before 1989 without the government interference. (4) Less than 10% of adult farmer s of age 25-64 in 1969 enrolled in Farm Discussion Club, only 5% of adult farm women enrolled in Home Economics Club, and 5% of rural youth enrolled in 4-H Club. These statistics show a fact that only few farmers are reached by extension workers. Based on findings in this paper, some important suggestions are listed for future agricultural development. (1) Improve agricultural structure by decreasing agricultural population (a) Encourage farmers with less than 0.5 ha. of land to seek jobs outside of agriculture (b) Encourage joint cultivation and farm mechanization (c) Discourage rural migrants to Keep farm land (d) Provide occupational guidance program through extension education programs (2) Establish future farmers settlement project to assure rural youth have enough resources for farming. (3) An optimum Population policy should be integrated into rural socio-economic development and national development programs.

• The Korean Journal of Ecology
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• v.23 no.4
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• pp.293-298
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• 2000

To study the effect of global warming on the growth of plants and plant populations throughout their life cycle under a field-like condition, we constructed a Temperature Gradient Chamber (TGC) in Tsukuba, Japan. The chamber had slender shape : 30 m long. 3 m wide, and 2.5 m high. That satisfactory performance was confirmed by a test throughout all seasons in 1998: the projected global warming condition in the near future was simulated. That is, independent of a great daily or seasonal change in ambient meteorological conditions, air temperatures at the air outlet were warmed 5$^{\circ}C$ higher than those at the ambient (the annual mean was 14.3$^{\circ}C$) with precision of ${\pm}$0.2$^{\circ}C$ (the annual means were 19.2$^{\circ}C$) with a rising rate of approximately 1$^{\circ}C$ every 5 m. This chamber will enable us to study the effects of global warming on growth of plants and plant populations because their abilities to control air temperature are excellent. TGC is expected that it would be utilized for studying the effect of global warming on plant growth under natural weather conditions.

• Korean journal of applied entomology
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• v.39 no.3
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• pp.141-147
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• 2000

This study was carried out to investigate the population changes of Liriomyza trijolii (Burgess) on chrysanthemum and its relationship to plant growth and damages. In spring culture of chrysanthemum, L. trifolii adults begun to be attracted by the yellow sticky trap from early May and maintained high population until the middle of July. Larval density increased gradually from late May and reached peak in early July. In autumn culture, the population density of adult was lower than that of spring culture but the number of adult was great in late September and the middle of October. This trend was similar to that of larval stage. Damaged leaves by larva could be found from 4 weeks after transplanting and its rate was low until 5 weeks but increased abruptly after 6 weeks and maintained 70% level until flowering stage in spring culture. Damaged leaves increased with plant growth in some varieties tested in this experiment.

• The Korean Journal of Soil Zoology
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• v.9 no.1_2
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• pp.16-23
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• 2004

This study estimated the mound and termite population density in the two study plots in Durokkopin Nature Reserve, Western Australia between 2003 and 2004. The mound density and size were greater in the woodland than in the shrubland. The annual growth rate of mounds was minimal. Some mounds decreased in volume during the 14 month observation period in both study plots. There were no significant differences in the termite population per mound or in the proportion of each caste between the two study plots. The size of the termite population in the mound progressively increased from the small to larger mounds. Overall, of the two favoured habitats, woodland appears to be more optimal for this termite species than the shrubland.