• 제목/요약/키워드: Polytetrafluoroethylene (PTFE)

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액체성 화학작용제의 흡수를 차단하는 피부보호제 제제 설계 연구 (Study on the formulations for Topical Skin Protectant against Liquid-Phase Chemical Warfare Agents)

  • 김상웅;서동성;손홍하;유치호;조혜은;조영
    • 한국군사과학기술학회지
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    • 제25권2호
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    • pp.210-217
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    • 2022
  • Chemical warfare agents(CWA) such as nerve agents and vesicating agents show lethality by skin contamination. Skin protection, therefore, is one of the top priorities to deal with the growing threat from CWA. In an attempt to develop the most effective topical skin protectant(TSP), candidate substances including PFPE(perfluorinated polyether), PTFE(polytetrafluoroethylene), glycerin, and polysaccharides were evaluated in forms of various formulations against nerve agent simulant DMMP(dimethylmethyl phosphonate) penetration. The protective efficacy of the formulation against DMMP penetration was estimated as the onset time of color change of the KM9 chemical agent detection paper. Based on this study, it was found that several PFPE- and glycerin-based formulations exhibit remarkably superior efficacy as a protective cream. This protective cream is expected to be used as TSP for military application after further research.

성견의 외과적 치근이개부 골결손에 차폐막과 골이식재를 이용한 조직유도재생술시 치유양상 (Guided Tissue Regeneration Using Barrier Membrane and Osseous Grafts in Surgically Created Furcation Defects in Dogs)

  • 정은희;정현주
    • Journal of Periodontal and Implant Science
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    • 제26권4호
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    • pp.967-987
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    • 1996
  • The present study was to evaluate the healing patterns of guided tissue regeneration( GTR) using resorbable $Vicryl^{(R)}$(polyglactin 910) mesh and nonresorbable expanded polytetrafluoroethylene(ePTFE) membrane with or without bone grafting using autogeneous bone and demineralized freeze-dried bone allograft(DFDBA) in the grade II furcation defects. Mucoperiosteal flaps were reflected buccally in the mandibular 2nd, 3rd and 4th premolar areas and furcation defects were created surgically by removing $5{\times}6mm$ alveolar bone in 4 dogs. Root surfaces were thoroughly debrided of periodontal ligament and cementum, and notches were placed on root surface at the most apical bone level. In the right and left mandibular quadrant, each tooth was received $Vicryl^{(R)}$ mesh(ACE Surgical Supply Co., USA) only, $Vicryl^{(R)}$ mesh with DFDBA, $Vicryl^{(R)}$ mesh with autogeneous bone grafts, ePTFE membrane($Core-tex^{(R)}$ membrane, W.L. Gore & Associates Inc., USA) only, ePTFE membrane with DFDBA or ePTFE membrane with autogeneous bone grafts. For the fluorescent microscopic examination, fluorescent agents were injected at 2, 4 and 8 weeks after surgery. Four weeks after surgery, 2 dogs were sacrificed and ePTFE membranes were removed from remaining 2 dogs, which were sacrificed at 12 weeks after surgery. Undecalcified tissues were embedded in methylmethacrylate and $10{\mu}m$ thick sections were cut in a buccolingual direction. These sections were stained with hematoxylin-eosin stain and Masson's trichrome stain, and evaluated by descriptive histology and linear measurements. The results were as follows : 1) $Vicryl^{(R)}$ mesh group showed less connective tissue attachment than ePTFE membrane group. 2) The combination of GTR using $Vicryl^{(R)}$ mesh and osseous grafts resulted in new attachment and new bone formation more than GTR using $Vicryl^{(R)}$ mesh only. 3) GTR using ePTFE membrane, with or without osseous grafts, enhanced periodontal regeneration. 4) Root resorption and dentoalveolar ankylosis were observed in the areas treated with the combination of GTR and DFDBA. It was suggested that the effect of adjunctive bone grafting in GTR procedure depends on the materials and the physical properties of barrier membranes. $Vicryl^{(R)}$ mesh performed a barrier function and the use of adjunctive bone grafting may enhance the periodontal regeneration.

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상대정맥을 침범한 흉부종양의 수술적 치료 (Superior Vena Cava Resection and Reconstruction in Thoracic Malignancy)

  • 한국남;강창현;김영태;전상훈;성숙환;김주현
    • Journal of Chest Surgery
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    • 제43권3호
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    • pp.273-279
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    • 2010
  • 배경: 상대정맥을 침범한 흉부 종양의 수술은 종양의 병기가 진행된 상태로 인하여 수술적 치료에 대한 보고가 흔하지 않았다. 본 연구에서는 상대정맥 침범 종양의 수술적 치료 결과에 대한 후향적 고찰을 시행하고자 하였다. 대상 및 방법: 2000년 5월부터 2009년 5월까지 상대정맥을 침범한 흉부 종양으로 본원에서 상대정맥의 부분 혹은 완전 절제술을 받은 환자 18명을 대상으로 하였고 성별은 남자 10명, 여자 8명, 수술 당시 평균 연령은 56.6세였다. 결과: 수술 방법은 Polytetrafluoroethylene (PTFE)도관을 이용한 재건술이 9예, 일차봉합이 6예, 첩포 성형술이 3예에서 시행되었다. 재원기간 중앙값은 14.5일(6~61), 추적 관찰기간 중앙값은 23개월(1~88)이었다. 전체 악성 종양 환자의 3년 생존율은 58.0%, 생존기간의 중앙값은 24.5개월이었다. 폐암, 종격동 종양에 따른 생존율과 무병율의 차이는 뚜렷하지 않았다. 상대정맥 재건술을 시행한 환자 중 1명에서 주도관인 상대정맥 도관의 폐쇄가 발생하였고 3명에서 부도관인 무명정맥 도관의 폐쇄가 발생하였다. 결론: 상대정맥을 침범한 폐암과 종격동 종양은 수술적 절제로 효과적으로 치료될 수 있었으며, 여러 가지 수술 후 합병증에도 불구하고 좋은 장기 생존율을 보여 이러한 환자 군에서 적극적인 수술적 치료가 고려되어야 한다고 판단된다.

가토에서 심낭대치물에 관한 실험적 연구 (Experimental Studies of the Pericardial Substitutes in Rabbits)

  • 백승환;양석린;김선한;남충희;이길노
    • Journal of Chest Surgery
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    • 제22권5호
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    • pp.724-730
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    • 1989
  • The development of severe pericardial adhesion after cardiovascular surgical procedures often increases the risk of injuring the heart, great vessels, or extracardiac grafts during resternotomy. Several pericardial substitutes have been tested in an attempt to facilitate reoperation with inconclusive results. This study was designed to evaluate the applicability of two different materials as pericardial substitutes to minimize the pericardial adhesion and epicardial reaction. A procedure for induction of pericardial adhesion was carried out in 30 rabbits. Rabbits were divided into three groups of ten rabbits each: Group 1[control, simple pericardial closure]: Group 2[bovine pericardium as pericardial substitute]: Group 3[e-polytetrafluoroethylene surgical membrane, e-PTFE as a pericardial substitute]. Bovine pericardium or e-PTFE surgical membrane was interposed between the sternum and the heart. Rabbits were sacrificed at 4 weeks after operation. The development of adhesions and epicardial reactions were graded as: none [I]; minimal[II]; moderate[Ill]; and severe[1V]. Histologic studies of the substitute, the pericardium, and the epicardium were performed. The results were as follows; l. In group 1[control group], the degree of pericardial adhesions were grade I in none, grade II in 1, grade III in 3, and grade 1V in 6 animals. Epicardial reactions were grade I in none, grade II in 3, grade K in 4, grade 1V in 3 animals respectively. 2. In group 2[bovine pericardium], the degree of pericardial adhesions were grade I in 1, grade II in 5, grade III in 3, and grade 1V in 1 animal. Epicardial reactions were grade I in 1, grade II in 2, grade III in 4, and grade 1V in 3 animals respectively. 3. In group 3[e-PTFE], the degree of pericardial adhesions were grade I in 7 animals, grade II in 2, grade III in 1, and grade g in none. Epicardial reactions were grade I in 4, grade II in 3, grade III in 2, and grade IV in 1 animal respectively. Pericardial adhesions more than grade II were 90.9% in group 1, 40 % in group 2, and 10% in group 3. Pericardial adhesions were significantly reduced in group 3 compared to group 1 or 2. Epicardial reactions more than grade II were 70 % in group 1, 70 % in group 2 and 30 % in group 3. We concluded that this 0.1mm thick polytetrafluoroethylene surgical membrane is a suitable pericardial substitute to minimize the development of pericardial adhesion or epicardial reaction following cardiovascular surgery.

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Polytetrafluoethylene 인조혈관을 이용한 좌쇄골하동맥-좌폐동맥단락술에 관한 연구 (A study on left subclavian artery-left pulmonary artery shunt operation using polytetrafluoroethylene [PTFE])

  • 조중구;김근호
    • Journal of Chest Surgery
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    • 제16권1호
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    • pp.91-96
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    • 1983
  • A study was carried out to observe the clinical progress and results after modified Blalock-Taussing shunts on II patients with cyanotic complex heart diseases unsuitable for corrective surgery. The operation was performed by interposing a vascular prosthesis [PTEE] between the left subclavian artery and the left pulmonary artery. Vascular prostheses larger than the diameter of left subclavian artery were selected. The results were as follows: 1. The postoperative courses in 10 patients were uneventful without any complications. One patient died of low cardiac output syndrome immediate postoperatively. 2. The average value of RBC count before operations was 751.2291.68 [xl00]/cubic mm. It was decreased to 588.11 90.45 [xl 0,000]/cubic mm. After the operation. 3. The average value of Hemoglobin before operations was 20.07 3.01 mg/dl. The value was decreased to 15.361.68mg/dl after the operation. 4. The value of Hematocrit before operations was 62.878.89%. The value was decreased to 49.6 5.84% 5. Patency after the shunt operations using PTFE was good for maximal 16 months follow-up period. 6. The physiological impairment like anoxic spells, degree of cyanosis and other clinical symptoms were markedly improved after the shunt operations. Although a longer follow-up seems to be necessary to assess the validity of these shunts, the early results were encouraging.

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유전체 렌즈가 삽입된 고이득 Corrugated 혼 안테나 (A High Gain Corrugated Horn Antenna with Dielectric Lens)

  • 이호주;최재훈
    • 한국전자파학회논문지
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    • 제27권5호
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    • pp.486-489
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    • 2016
  • 논문에서는 corrugation 구조의 적용과 PTFE 테플론(비유전율=2.1) 유전체 렌즈의 삽입을 통하여 우수한 임피던스 매칭 특성과 고이득 성능을 가지는 corrugated 혼 안테나가 제안되었다. 제안된 안테나는 X 밴드(8~12 GHz)에서 -25 dB 이하의 측정 반사손실 성능을 가지고, 중심 주파수인 10 GHz에서 최대 이득이 22.3 dBi이며, 안테나의 전체 크기는 $110mm{\times}110mm{\times}135mm$이다. 제안된 안테나의 성능을 고려하였을 때, 레이더식 레벨 트랜스미터 시스템에 삽입되기에 적합하며, 특히 LNG 및 LPG와 같이 낮은 비유전율 및 반사율을 가지는 물질이 저장된 선박 혹은 해양플랜트 내부의 가스탱크에 적용될 수 있을 것으로 사료된다.

Behavior of Bridge Bearings for Railway Bridges under Running Vehicle

  • Choi, Eun-Soo;Yu, Wan-Dong;Kim, Jin-Ho;Park, Sun-Hee
    • International Journal of Railway
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    • 제5권1호
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    • pp.10-21
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    • 2012
  • Open steel plate girder (OPSG) bridges are the most prevalent railroad bridge type in Korea, constituting about 40% of all railroad bridges. Solid steel bearings, known as line type bearings, are placed in most OSPG railway bridges. However, the line type rigid bearings generate several problems with the bridge's dynamic behavior and maintenance in service. To compare and investigate the dynamic behaviors of line type, spherical and disk bearings, the vertical displacements of each bearing, including fixed and expansion type, under running vehicles are measured and analyzed. The displacements of disk and spherical bearings are measured after replacing the line type bearings with spherical and disk bearings. This study also analyzed dynamic behaviors of bridges. Furthermore, the deformation of the PTFE (Polytetrafluoroethylene) plate that is placed inside of expansion type spherical and disk bearings is measured and its effect on the dynamic behavior of the bridges is discussed. The up-lift phenomenon at the bearings installed for the steel bridges is estimated. The vertical displacements at mid-span of the bridges are compared according to the bearing types. Finally, the 1st mode natural frequencies are estimated, and the relationship to the vertical displacement is discussed.

중년 여자 환자에서 비전형적 Middle Aortic Syndrome의 수술치험 1예 (Atypical Middle Aortic Syndrome in a Middle Aged Woman -A case report-)

  • 김우식;배윤숙;정성철;신용철;유환국;김병열
    • Journal of Chest Surgery
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    • 제37권1호
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    • pp.80-83
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    • 2004
  • 원위 흉부 대동맥이나 복부 대동맥 혹은 두 부위가 좁아져 있는 Middle aortic syndrome (이하 MAS) 또는 mid aortic dysplastic syndrome은 매우 드물게 발생한다. 원인이 불분명하고 흔히 젊은 여성에게서 잘 나타나는 이 질환은 뇌출혈뿐만 아니라 심장, 신장의 손상을 초래할 수 있으므로 적극적인 수술적 치료로 혈류를 개선하여 효과를 볼 수 있으나 대동맥 혈관의 섬유화로 인한 수술 술기의 어려움이 따른다. 최근 국립의료원 흉부외과에서는 광범위한 석회화 병변을 동반한 하부 대동맥협착을 가진 51세 여자 환자에서 6.0-mmPTFE (polytetrafluoroethylene) 인조혈관을 이용하여 양측 액와-대퇴 동맥간 우회로술을 시행함으로써 우수한 수술 결과를 보였기에 보고하는 바이다.

코로나 대전 일렉트렛트로 제작된 초저주파 변환기의 개발 (Development of Infra-sonic Transducer Manufactured by Corona Charging Electret)

  • 송재열;정동회;김상걸;안준호;김성열;이준웅
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2000년도 하계학술대회 논문집
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    • pp.942-945
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    • 2000
  • Recently, electret applications have placed the focus on polymer thin film because electrical properties of a blend are studied. In this paper, we hale measured the infra sonic frequency by using Electret Sensor. Electret is formed by appling the voltage range of -4[kV] to -8[kV] to PTFE film and the sensor is manufactured by moment method to detect the infra-sonic signal. Electret Infrasonic Transducer, which is designed and manufactured by using of the moment method according to the potential and electric field simulation , shows its promising result, since the average rising rate of sensitivity is 7.68 [dB/oct] under 1[Hz], and the average values are within ${\pm}$ 1 [dB/oct]. As a result, it is believed that the characteristics of acquired transducer can be applied to the medical treatment, the industry, and the animal life researches, and also the study on noise elimination is required.

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무기인산염과 탈단백우골의 혼합사용이 골재생에 미치는 효과 (Effect of deproteinized bovine bone mineral soaked in inorganic polyphosphate on bone regeneration)

  • 나성윤;권영혁;박준봉;허익;정종혁
    • Journal of Periodontal and Implant Science
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    • 제37권1호
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    • pp.77-89
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    • 2007
  • This study was performed to evaluate the effect of deproteinized bovine bone mineral soaked in inorganic polyphosphate on bone regeneration in the calvaria of rabbit in the procedure of guided bone regeneration with titanium reinforced expanded polytetrafluoroethylene(TR-ePTFE) membrane. The rabbits were divided into four groups. Control group used TR-ePTFE membrane filled with de-proteinized bovine bone mineral, experimental group I used TR-ePTFE membrane and deproteinized bovine bone mineral soaked in 4% inorganic polyphosphate, experimental group II and III used TR-ePTFE membrane and deproteinized bovine bone mineral soaked in 8% or 16% inorganic poly-phosphate respectively. After decortication in the calvaria, GBR procedure was performed on 8 rabbits with only TR-ePTFE membrane or titanium reinforced ePTFE membrane filled with deproteinized bovine bone mineral soaked in inorganic polyphosphate. The animals were sacrificed at 4 weeks, and 8 weeks af-ter the surgery. Non-decalcified specimens were processed for histologic analysis, and new bone for-mation was assessed by histomorphometric as well as statical analysis. 1. Both control group and experirrental group dermnstrated increasing of new bone formation until 8weeks. 2. At 8 weeks, experimental group I and group II showed the significant difference compared to control group in new bone formation. Especially experimental group II showed the most in-creasing of new bone formation. 3. The higher concentration of inorganic polyphosphate filled, the more volume of bone formation pro-moted, but experimental group III did not reveal significant difference compared to contol group. 4. Deproteinized bovine bone mineral did not resorbed at all until 8 weeks. These results suggest that inorganic polyphosphate has a promoting effect on bone regeneration. possibly by enhancing osteoconductivity of the carrier and by increasing osteoinductivity of the defected alveolar bone tissue, but not as we respect.