• Journal of Pharmaceutical Investigation
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• 제21권4호
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• pp.237-245
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• 1991

Matrix type silicone rubber devices were designed for long-term implantable drug delivery system. Release controlling agents (RCA), i.e., polypropylene glycol, polyethylene glycol, were employed to control drug release from the devices. The release rate of drug from RCA dispersed silicone matrices was mainly dependent on hydrophilicity-hydrophobicity of drug and RCA. In the case of hydrophilic drug, the release from the RCA dispersed matrix was regulated by swelling kinetics. Especially when the relatively hydrophobic polypropylene glycol was used, swelling control mechanism induced zero-order release kinetics. Whereas, the release of hydrophobic drug was resulted from partition mechanism. The effect of RCA was to increase drug diffusivity.

• 한국의류학회지
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• 제21권6호
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• pp.1041-1050
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• 1997

This study was carried out to improve the thermal insulation properties of wool and wool- like fabrics by treating the fabrics with polyethylene glycol, to evaluate the fabric hand of PEG treated wool and wool-like fabrics and to grade up the fabric hand of the treated fabrics by treating with softening agents. Wool and wool-like fabrics were treated with high molecular PEG-8,000 by PDC. The thermal release/storage properties were measured on a DSC. Hand of specimens were evaluated by KES-FB system. The results were as follows; 1. PEG-treated fabrics showed thermal storage and thermal release properties by DSC and the heat contents were generally proportional to the add-ons. 2. PEG-treated fabrics showed higher Koshi and lower Numeri and Sofutosa values due to lower tensile energy and recovery and higher bending rigidity and shear stiffness as the add- ons increased. 3. PEG-treated fabrics showed much lower bending rigidity after softening agents treatment.

• 대한화학회지
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• 제53권4호
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• pp.415-421
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• 2009

수용액에서 다양한 알데히드 5, 5-dimethyl-1, 3-cyclohexanedione을 이용한 1, 8-Dioxo-octahydroxanthene 유도체의 편리하고 실용적인 합성이 촉매인 폴리에틸렌 글리콜(PEG)하에서 성공적으로 수행되었다. 간단한 work-up, 깨끗한 생성물, 높은 수율, 친환경적인 용매인 물의 사용은 이 방법의 특색이다.

• BMB Reports
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• 제29권3호
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• pp.261-265
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• 1996

Sheep hemoglobin (SHb) was modified with methoxy-polyethylene glycol (mPEG) to develop a potential blood substitute. mPEG has been used to decrease antigenicity and immunogenicity of foreign proteins. When the mPEG was attached to SHb, the modified hemoglobins showed decreased electrophoretic mobility on SDS-PAGE and decreased free amino groups. When the remaining free amino groups of mPEG modified SHb were determined by TNBS free amino group titration methods. about 34% of total free amino groups were modified with mPEG. This mPEG-SHb conjugate of 34% amino groups modified showed no precipitation by double immunodiffusion with polyclonal antibodies against SHb. This modified hemoglobin still has oxygen transport activity. So this antigenicity decreased hemoglobin may be used in humans as a potential blood substitute.

• Journal of Pharmaceutical Investigation
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• 제24권4호
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• pp.257-263
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• 1994

The interpenetrating polymer networks (IPNs) of polyacrylic acid (PAA)-polyethylene glycol (PEG) were synthesized via crosslinking of PEG and simultaneous free radical polymerization of PAA. The equilibrium swelling of the IPNs matrices, ranged from 40% to 95%, was varied to a great extent as compared with PAA homopolymer due to the interpolymer interaction between PAA and PEG. The drug release kinetics of drug loaded matrices was significantly affected by the charge of drugs as well as interpolymer complexation.

• Membrane and Water Treatment
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• 제8권6호
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• pp.591-612
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• 2017

Increase in the hydrophilicity (HPCT) of polysulfone (PS) membrane and subsequently decrease in fouling can be achieved by surface modification of PS based membranes. Therefore, in this work, ultrafiltration membranes with increased HPCT were prepared using the enantiomeric tartaric acid (D-TA) and racemic tartaric acid (DL-TA). Phase inversion technique was used for the preparation of polyethylene glycol and TA blended PS membrane. Morphological analysis of the fabricated membranes was done by scanning electron microscope and atomic force microscopy. Bovine serum albumin (BSA) solution was taken for finding the permeation and rejection behavior of prepared membranes. Maximum BSA rejection was increased by 70.5% for the modified membrane.

• 한국가구학회지
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• 제13권1호
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• pp.2-8
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• 2002

This study was carried out to investigate the reasonable condition for better dimensional stability in woods by polyethylene glycol(PEG) treatment. Eight species grown in Kangwon-do were used for this study. Three species of softwoods(Pinus densiflora, Pinus koraiensis, Larix kaempferi) and two species of hardwoods(Prunus sargentii, Populus tomentiglandulosa) treated with 30% aqueous solution of PEG 1000 showed good dimensional stability under the treatment for 1 day. The dimensional stability of Betula davurica, Quercus mongolica and Quercus variabilis woods increased with increasing treatment time. From the above results, it was concluded that PEG penetration and dimensional stability were affected by characteristics of wood species such as density and structure.

• Journal of Pharmaceutical Investigation
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• 제25권4호
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• pp.313-322
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• 1995

The covalent conjugation of human recombinant superoxide dismutase (hrSOD) with trichloros-triazine activated polyethylene glycol (PEG) 5000 formed soluble conjugates with molecular weight of 92KD, which retained $90{\sim}98%$ of original activity with a markedly prolonged plasma half-life of enzyme activity. The effect of hrSOD-PEG conjugates on acetaminophen (ACP)-induced hepatotoxicity was tested in male rats which were pretreated with 3-methylcholanthrene. HrSOD-PEG conjugates inhibited the hepatotoxicity produced by ACP, on the other hand, native hrSOD had no protective effect. The above results indicated that oxygen radicals might participate in the mechanism of the ACP-induced hepatotoxicity and that polymer conjugated-protein drugs with prolonged half-lives could be employed as an effective therapeutic agent.

• 한국응용과학기술학회지
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• 제29권1호
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• pp.54-62
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• 2012

본 실험에서는 투명비누를 만드는데 사용되는 폴리올의 최적 농도를 실험계획법을 이용하여 결정하였다. 짧은 사슬을 보유한 디프로필렌글리콜과 1,3 부틸렌글리콜은 비누의 투명도를 증가시켰으나 폴리에틸렌글리콜 400, 글리세린과 디글리세린은 비누를 불투명하게 하였다. 프로필렌글리콜, 디글리세린, 디프로필렌글리콜 및 폴리에틸렌글리콜의 농도를 증가시키면 비누의 경도는 증가하였다. 경도, 투명도, 물의 흡수성 및 마찰 용해도는 디프로필렌글리콜, 폴리에틸렌글리콜, 설탕과 트리에탄올아민의 농도를 조절하여 최적화할 수 있었다.

• 한국염색가공학회지
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• 제30권2호
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• pp.90-97
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• 2018

Hydrophilic reactive hot-melt polyurethane adhesive(HRHA) using a hydrophilic polyol having different molecular weight and NCO index was synthesized. This HRHA was synthesized using Polyethylene glycol(PEG) as a hydrophilic polyol, Polypropylene glycol(PPG) and Polycaprolactone diol(PCL) as hydrophobic polyols, and Methylene diphenyl diisocyanate(MDI) as an isocyanate. The changes in IR spectrum, viscosity and thermal properties of HRHA with different PEG molecular weights and NCO index were investigated, and the tensile strength and elongation of the HRHA casting film and the peel strength, moisture permeability and water pressure of the HRHA coated fabric were confirmed. In this experiment, as the molecular weight of PEG and NCO index increased, the adhesive strength, tensile strength, elongation and moisture permeability was increased but viscosity and Tg was decreased.