• 제목/요약/키워드: PolA

검색결과 214건 처리시간 0.025초

Molecular Characterization of the HERV-W Env Gene in Humans and Primates: Expression, FISH, Phylogeny, and Evolution

  • Kim, Heui-Soo;Kim, Dae-Soo;Huh, Jae-Won;Ahn, Kung;Yi, Joo-Mi;Lee, Ja-Rang;Hirai, Hirohisa
    • Molecules and Cells
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    • 제26권1호
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    • pp.53-60
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    • 2008
  • We characterized the human endogenous retrovirus (HERV-W) family in humans and primates. In silico expression data indicated that 22 complete HERV-W families from human chromosomes 1-3, 5-8, 10-12, 15, 19, and X are randomly expressed in various tissues. Quantitative real-time RT-PCR analysis of the HERV-W env gene derived from human chromosome 7q21.2 indicated predominant expression in the human placenta. Several copies of repeat sequences (SINE, LINE, LTR, simple repeat) were detected within the complete or processed pseudo HERV-W of the human, chimpanzee, and rhesus monkey. Compared to other regions (5'LTR, Gag, Gag-Pol, Env, 3'LTR), the repeat family has been mainly integrated into the region spanning the 5'LTRs of Gag (1398 bp) and Pol (3242 bp). FISH detected the HERV-W probe (fosWE1) derived from a gorilla fosmid library in the metaphase chromosomes of all primates (five hominoids, three Old World monkeys, two New World monkeys, and one prosimian), but not in Tupaia. This finding was supported by molecular clock and phylogeny data using the divergence values of the complete HERV-W LTR elements. The data suggested that the HERV-W family was integrated into the primate genome approximately 63 million years (Myr) ago, and evolved independently during the course of primate radiation.

주기적 회전을 이용한 원봉 후류의 되먹임 제어 (Feedback Control of a Circular Cylinder Wake with Rotational Oscillation)

  • 백승진;성형진
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2001년도 춘계학술대회논문집E
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    • pp.265-270
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    • 2001
  • This study presents a feedback control methodology for suppression of the vortex shedding from a circular cylinder in a uniform flow. A rotational oscillation is applied as a controlled forcing and the lift coefficient ($C_L$) is used as a feedback signal. A feedback control concept is made based on the phase relation between the rotation velocity and $C_L$ at 'lock-on', The phase between the forcing and the vortex formation is changed $180^{\circ}$ from the phase of enhancing the lock-on state. This concept is examined by solving the Van del Pol equation. The results are satisfactory.

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거리 영상에서 인식 특정을 이용한 경계선 검출 기법 (A method of extracting edge line from range image using recognition features)

  • 이강호
    • 한국컴퓨터정보학회논문지
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    • 제6권2호
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    • pp.14-19
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    • 2001
  • 본 논문은 2차 다항식을 이용하여 3차원 물체의 표면 특징을 추출하고 표현하는 방법을 제안한다. 우리는 수정된 스캔 라인 기법을 이용하여 에지 맵을 얻는다. 에지 맵으로부터 3차원 물체의 각 면들을 분리하기 위해 레이블링 연산을 하고 각 면에서 중심점과 모서리 점들을 추출한다. 그 다음에, 평면 방정식으로부터 각 면이 평면인지 곡면인지를 판단하고, 3차원 물체를 표현하기 위해 각 면의 평면 또는 곡면의 계수 및 특징들을 추출한다. 그리고 합성영상과 실측영상을 통해서 제안된 기법의 성능을 알아보았다.

A neural network approach for simulating stationary stochastic processes

  • Beer, Michael;Spanos, Pol D.
    • Structural Engineering and Mechanics
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    • 제32권1호
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    • pp.71-94
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    • 2009
  • In this paper a procedure for Monte Carlo simulation of univariate stationary stochastic processes with the aid of neural networks is presented. Neural networks operate model-free and, thus, circumvent the need of specifying a priori statistical properties of the process, as needed traditionally. This is particularly advantageous when only limited data are available. A neural network can capture the "pattern" of a short observed time series. Afterwards, it can directly generate stochastic process realizations which capture the properties of the underlying data. In the present study a simple feed-forward network with focused time-memory is utilized. The proposed procedure is demonstrated by examples of Monte Carlo simulation, by synthesis of future values of an initially short single process record.

주기적 회전을 이용한 원봉 후류의 되먹임 제어 (Feedback Control of a Circular Cylinder Wake with Rotational Oscillation)

  • 이상봉;백승진;성형진
    • 한국전산유체공학회:학술대회논문집
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    • 한국전산유체공학회 2005년도 춘계 학술대회논문집
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    • pp.51-56
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    • 2005
  • A new feedback control system based on system identification is proposed and preliminarily tested on Van der Pol equation which has a similar characteristic to circular cylinder. The same principle is applicable to circular cylinder in a uniform flow for suppresing the vortex shedding. The feedback controller is designed to impose feedback signal at the phase which is located outside the range of lock-on. The lift coefficient (CL) is employed as a feedback signal and the control forcing is given by a rotational oscillation of the cylinder. By applying the feedback control system, the lift coefficient is reduced.

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훅조인트로 연결된 축계의 비선형 비틀림 진동의 분기해석 :2-자유도계 모델 (Nonlinear Torsional Oscillations of a System incorporating a Hooke's Joint : 2-DOF Model)

  • 장서일
    • 한국소음진동공학회논문집
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    • 제13권4호
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    • pp.317-322
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    • 2003
  • Torsional oscillations of a system incorporating a Hooke's joint are investigated by adopting a nonlinear 2-degree-of-freedom model. Linear and Van der Pol transformations are applied to obtain the equations of motion to which the method of averaging can be readily applied. Various subharmonic and combination resonances are identified with the conditions of their occurrences. Applying the method of averaging leads to the reduced amplitude- and phase-equations of motion, of which constant and periodic solutions are obtained numerically. The periodic solution which emerges from Hopf bifurcation point experiences period doubling bifurcation leading to infinite solution rather than chaotic solution.

엑시머 레이저를 이용하여 동시에 형성된 실리콘 산화막과 다결정 실리콘 박막 (Silicon oxide and poly-Si film simultaneously formed by excimer laser)

  • 박철민;민병혁;전재홍;유준석;최홍석;한민구
    • 전자공학회논문지D
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    • 제34D권1호
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    • pp.35-40
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    • 1997
  • A new method to form the gate oxide and recrystllize the polycrystalline silicon (poly-Si) active layer simultaneously is proposed and fabricated successfully. During te irradiation of excimer laser, the poly-Si film is recrystallized, while the oxygen ion impurities injected into the amorphous silicon(a-Si) film are activated by laser energy and react with silicon atoms to form SiO2. We investigated the characteristics of the sample fabricated by proposed method using AES, TEM, AFM. The electrical performance of oxide was verified by ramp up voltage method. Our experimental results show that a high quality oxide, a pol-Si film with fine grain, and a smooth and clean interface between oxide and poly-Si film have been successfully obtained by the proposed fabrication method. The interface roughness of oxide/poly-Si fabricated by new method is superior to film by conventional fabrication os that the proposed method may improve the performance of poly-Si TFTs.

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Input Time-Delay Compensation for a Nonlinear Control System

  • Choi, Yong-Ho;Chong, Kil-To
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2004년도 ICCAS
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    • pp.395-400
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    • 2004
  • In most physical processes, the transfer function includes time-delay, and in the general distributed control system using computer network, there exists inherent time-delay caused by the spatial separation between controllers and actuators. This work deals with the synthesis of a discrete-time controller for a nonlinear system and proposes a new effective method to compensate the influence of input time-delay. The controller is synthesized by using input/output linearization. Under the circumstance that input time-delay exists, the system response has more overshoot and tends to diverge. For these reasons, the controller has to produce future input value that will be needed for the system. In order to calculate the future input value, some predictors are adopted. Using the discretization via Euler's method, numerical simulations about the Van der Pol system are performed to evaluate the performance of the proposed method.

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The diverse roles of RNA polymerase II C-terminal domain phosphatase SCP1

  • Harikrishna, Reddy R.;Kim, Hackyoung;Noh, Kwangmo;Kim, Young Jun
    • BMB Reports
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    • 제47권4호
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    • pp.192-196
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    • 2014
  • RNA polymerase II carboxyl-terminal domain (pol II CTD) phosphatases are a newly emerging family of phosphatases that are members of DXDX (T/V). The subfamily includes Small CTD phosphatases, like SCP1, SCP2, SCP3, TIMM50, HSPC129 and UBLCP. Extensive study of SCP1 has elicited the diversified roles of the small C terminal domain phosphatase. The SCP1 plays a vital role in various biological activities, like neuronal gene silencing and preferential Ser5 dephosphorylation, acts as a cardiac hypertrophy inducer with the help of its intronic miRNAs, and has shown a key role in cell cycle regulation. This short review offers an explanation of the mechanism of action of small CTD phosphatases, in different biological activities and metabolic processes.

BVP 오실레이터 모델에서의 미소 파라미터 섭동에 의한 카오스 제어 및 하드웨어 구현 (The study of Controlling chaos for BVP oscillation model by small parameter perturbation and hardware implementation)

  • 배영철;서삼문;임화영
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1995년도 추계학술대회 논문집 학회본부
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    • pp.154-156
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    • 1995
  • The effect of a periodic and a chaotic' behaviour in the Bonhoeffer-Van der Pol(BVP) oscillation of the nerve membrane driven by a periodic stimulating current $A_1=cos\;{\omega}\;t$ are investigated by numeric analysis and hardware Implementation. To control the chaotic motion, we are suggested by temperature parameter c, $c=c(1+\eta\;cos\;{\Omega}\;t)$ which the values of $\eta,\;Omega$ varied respectively. The feasibilities of chaotic and periodic phenomena were analysed by phase plane and time series.

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