• 대한세포병리학회지
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• 제9권1호
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• pp.117-121
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• 1998

Cytologic features of a poorly differentiated "insular" carcinoma of the thyroid are presented. In fine needle aspiration cytology, the aspirates were highly cellular and tumor cells were arranged in loose cluster or singly dispersed on focally necrotic background. Occasional microfollicles were evident. The tumor cells had poorly defined, scanty cytoplasm and most of the nuclei were fairly uniform with coarse chromatin pattern. A few large pleomorphic cells were also noted. The cytologic findings of the present case were correlated well with the histologic findings, which showed typical insular pattern and the presence of uniform cells with occasional pleomorphism.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제14권2호
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• pp.113-121
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• 2011

Food allergies affect 7~8% of infants and young children, and their prevalence appears to have increased in recent years. Food allergy refers to an abnormal immunological reaction to a specific food. These reactions can be recurrent each time the food is ingested. Food allergy manifests itself with a wide spectrum of clinical characteristics including IgE-mediated diseases as immediate reactions, non-IgE-mediated disorders as delayed reactions, and mixed hypersensitivities. As a consequence, the clinical picture of a food allergy is pleomorphic. A well-designed oral food challenge is the most reliable diagnostic test for infants and young children whose clinical history and physical examination point towards a specific food allergy. Food specific IgE antibody tests (RAST, MAST, skin prick test, Uni-CAP, etc) are an alternative tool to determine oral food challenge for IgE-mediated disorders, but not for non-IgE-mediated allergies. Moreover, parents often impose their children on unnecessary diets without adequate medical supervision. These inappropriate dietary restrictions may cause nutritional deficiencies. This review aims to introduce clinical perspectives of food allergy in infants and young children and to orient clinicians towards different strains of diagnostic approaches, dietary management, and follow-up assessment of tolerance development.

• 대한수의학회지
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• 제42권3호
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• pp.389-392
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• 2002

A 17-year-old female tiger (Panthera tigris altica) was found dead after suffering from continuously growing mass at the right mammary gland area. At necropsy, a firm tan mass approximately 25 cm in diameter was noted at the ventral abdomen. The mass was not fixed to the adjacent tissue and mottled tan to red on cut sections. Chains of similar nodules ranging from 2 to 5 cm in diameter were also present along the right mammary glands region. Histologically, the neoplastic masses consisted of lobules that were filled with pleomorphic neoplastic cells and separated by fibrious conntective tissue. The neoplastic cells have hyperchromatic nuclei with prominent nucleolus and moderate amount of cytoplasm. The degree of mitosis was high. Multiple areas of necrosis, hemorrhage, mineralization and tumor emboli were also noted. Metastasis to the regional lymph nodes, lung, liver, spleen, kidney, and adrenal gland were observed. Based on the gross and histopathologic examinations, a diagnosis of lobular type metastatic mammary gland carcinoma was made.

• 대한두경부종양학회지
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• 제26권1호
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• pp.24-26
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• 2010

Necrotizing sialometaplasia was defined by Abrams et al. in 1973 as a reactive necrotizing inflammatory process involving minor salivary glands. Prior to recognition of necrotizing sialometaplasia as a benign, self-limited lesion, it was all too often diagnosed as either squamous cell carcinoma or mucoepidermoid carcinoma and had been improperly treated because of its clinical and histological resemblance to malignancy. We report two cases of necrotizing sialometaplasia. One case involved a 56-year-old female who developed a necrotizing sialometaplasia in association with palato-pharyngeal flap wound after excision of soft palate cancer and reconstruction. Another case involved a 55-year-old male who had a soft palate mass.

• 대한두경부종양학회지
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• 제29권1호
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• pp.11-13
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• 2013

Warthin's tumor is the second most common tumor of the parotid gland after pleomorphic adenoma. It is well known to occur as bilateral and multiple patterns. The incidence of extraparotid Warthin's tumor (EPWT) is about 2.7% to 12%, peri-parotid and upper cervical area are the most common sites. Warthin's tumor with synchronous intraparotid and extraparotid area is extremely rare, only a few cases have been reported. We report a-71-year old man with unilateral swelling of the parotid area and upper neck, pathologically confirmed Warthin's tumor with literature review.

• Journal of Korean Neurosurgical Society
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• 제48권3호
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• pp.276-280
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• 2010

Liposarcomas are malignant tumors of the soft tissue, with myxoid liposarcoma being the second most common subtype, tending to occur in the limbs, particularly in the thighs. Myxoid liposarcomas have an intermediate prognosis between well-differentiated and pleomorphic tumors. Spinal metastasis is usual but intradural involvement is extremely rare. We present an unusual case of a multicentric myxoid liposarcoma with intradural involvement. A 41-year-old woman complained of tingling sensation on her left arm. Radiological evaluation revealed multiple masses in her cervical spine, abdominal wall, liver, heart and right thigh, all of which were resected. She was histologically diagnosed with small round cell myxoid sarcoma and underwent adjuvant chemotherapy. However, magnetic resonance imaging analysis after 1 year revealed a large metastatic mass with bony invasion at the C6-T1 level. This mass consisted of extradural and intradural components causing severe compression of the spinal cord. She underwent resection via a posterior facetectomy of C6-7 and an anterior C7 corpectomy. However, the patient died of multiple metastases 18 months after the first diagnosis.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제35권5호
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• pp.384-387
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• 2009

Tumors of the deep lobe of parotid gland are rare. These benign tumors have usually been treated by total parotidectomy, which has functional and esthetic side effects. Recently, there has been a trend for operations of parotid gland benign tumors to be less radical and selective deep lobe parotidectomy has been introduced. This technique preserves the superficial lobe and facial nerve when tumor is located in the deep lobe. Selective deep lobe parotidectomy preserves parotid salivary function, minimizes the incidence of facial nerve damage and gustatory sweating (Frey's syndrome) and improves cosmetic outcome. We report a case of pleomorphic adenoma of the deep lobe that was successfully treated by selective deep lobe parotidectomy with satisfactory result.

• Asian Pacific Journal of Cancer Prevention
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• 제14권1호
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• pp.27-30
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• 2013

Background: Salivary gland tumors (SGT) are one of the most complex human neoplasms, demonstrating variations in their clinicopathological profile related to racial and geographic differences. Few studies with large samples have been reported in Iran. We here investigated a large group of patients in southern Iran. Materials and Methods: In this retrospective study, all cases of primary epithelial salivary gland tumors, which had been recorded in a 5 years period from 2005-2009, were enrolled. Clinical data such as histopathologic type and site of the lesion as well as patients' age and gender were analyzed. Results: Data of 366 cases of SGTs were recorded. Pleomorphic adenoma (80.2%) and adenoid cystic carcinoma (46.6%) were the most common benign and malignant neoplasms. Male to female ratio (M/F) and the mean age of patients were 1:1.05 and 37.7 for benign tumors while they were 1.2:1 and 50.6 for malignant tumors, respectively. Parotid and minor salivary glands were involved more frequently. Conclusions: Although the salivary gland tumours encountered were similar in most of their characteristics to those reported in other countries, some differences such as relative frequency and age and gender prevalence were discovered. These findings should help surgeons and pathologists for more accurate diagnosis, management and treatment.

• 대한치과의사협회지
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• 제22권10호통권185호
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• pp.865-868
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• 1984

Three Korean rapidly progressive periodontitis patient (R.P.P.) were examined for the isolation and identification of black-pigmented Bacteroides and Bacteroides gingivalis in the subgingival plaque. Black-pigmented Bacteroides and Bacteroides gingivalis were recovered from all three R.P. patients and the predominant isolates were Bacteroides intermedius followed by Bacteroides gingivalis. The B. gingivalis isolated from subgingival plaque of rapidly progressive periodontitis patients were Gram-negative pleomorphic rods and each produced brown to black colonies on blood agar plate supplemented with 5% rabbit 5ug/ml haemin, 0.5ug/ml of menadione and 40ug/ml of Kanamycin. The B. gingivalis isolated were fermented none of Glucose, Sucrose, Lactose, Esculin and Cellobinose and produced indole. Isolation and identification of Bacteroides gingivalis in Korean R.P. patients can be contributed to the research on the pathogenesis of Korean periodontal disease.

• 대한기관식도과학회지
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• 제7권2호
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• pp.146-151
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• 2001

Background and Objectives： Primary benign masses in subglottis and trachea are rare. Symptoms of tracheal obstruction are similar to those of bronchial asthma, chronic bronchitis, as well as malignant lesions. Materials and Methods： Eight patients with benign tracheal masses from April 1992 through June 2001, at otolaryngology-head and neck surgery. department of Seoul national university hospital were studied by retrospective medical record review. Results : They were 3 females and 5 males aged from 0 to 57 years. The pathologies of the intratracheal masses were lipoma. tuberculosis, pleomorphic adenoma, hemangioma(two case), reparative giant cell granuloma, epithelial inclusion cyst and nonspecific lymphadenopathy, respectively. The most characteristic symptoms were dyspnea and stridor, both inspiratory and expiratory. Five of them had been treated as bronchial asthma. Conclusion： For the management of patients with the subglottis and tracheal masses, it is important to establish secure airway. regardless of pathology of the masses. The diagnosis should be considered in any patient with asthma-like manifestation, especially who fails to respond to medical treatment. It is necessary to examine the airway thoroughly, and chest and simple cervical X-ray may contribute to the diagnosis of possible intratracheal mass.