• 한국의학물리학회지:의학물리
• /
• 제32권4호
• /
• pp.130-136
• /
• 2021

Purpose: The Halcyon radiotherapy platform at Groote Schuur Hospital was delivered with a factory-configured analytical anisotropic algorithm (AAA) beam model for dose calculation. In a recent system upgrade, the Acuros XB (AXB) algorithm was installed. Both algorithms adopt fundamentally different approaches to dose calculation. This study aimed to compare the dose distributions of cervical carcinoma RapidArc plans calculated using both algorithms. Methods: A total of 15 plans previously calculated using the AAA were retrieved and recalculated using the AXB algorithm. Comparisons were performed using the planning target volume (PTV) maximum (max) and minimum (min) doses, D95%, D98%, D50%, D2%, homogeneity index (HI), and conformity index (CI). The mean and max doses and D2% were compared for the bladder, bowel, and femoral heads. Results: The AAA calculated slightly higher targets, D98%, D95%, D50%, and CI, than the AXB algorithm (44.49 Gy vs. 44.32 Gy, P=0.129; 44.87 Gy vs. 44.70 Gy, P=0.089; 46.00 Gy vs. 45.98 Gy, P=0.154; and 0.51 vs. 0.50, P=0.200, respectively). For target min dose, D2%, max dose, and HI, the AAA scored lower than the AXB algorithm (41.24 Gy vs. 41.30 Gy, P=0.902; 47.34 Gy vs. 47.75 Gy, P<0.001; 48.62 Gy vs. 50.14 Gy, P<0.001; and 0.06 vs. 0.07, P=0.002, respectively). For bladder, bowel, and left and right femurs, the AAA calculated higher mean and max doses. Conclusions: Statistically significant differences were observed for PTV D2%, max dose, HI, and bowel max dose (P>0.05).

• Journal of Ginseng Research
• /
• 제46권3호
• /
• pp.464-472
• /
• 2022

Background: Gut microbiota influence the central nervous system through gut-brain-axis. They also affect the neurological disorders. Gut microbiota differs in patients with Alzheimer's disease (AD), as a potential factor that leads to progression of AD. Oral intake of Korean Red Ginseng (KRG) improves the cognitive functions. Therefore, it can be proposed that KRG affect the microbiota on the gut-brain-axis to the brain. Methods: Tg2576 were used for the experimental model of AD. They were divided into four groups: wild type (n = 6), AD mice (n = 6), AD mice with 30 mg/kg/day (n = 6) or 100 mg/kg/day (n = 6) of KRG. Following two weeks, changes in gut microbiota were analyzed by Illumina HiSeq4000 platform 16S gene sequencing. Microglial activation were evaluated by quantitative Western blot analyses of Iba-1 protein. Claudin-5, occludin, laminin and CD13 assay were conducted for Blood-brain barrier (BBB) integrity. Amyloid beta (Aβ) accumulation demonstrated through Aβ 42/40 ratio was accessed by ELISA, and cognition were monitored by Novel object location test. Results: KRG improved the cognitive behavior of mice (30 mg/kg/day p < 0.05; 100 mg/kg/day p < 0.01), and decreased Aβ 42/40 ratio (p < 0.01) indicating reduced Aβ accumulation. Increased Iba-1 (p < 0.001) for reduced microglial activation, and upregulation of Claudin-5 (p < 0.05) for decreased BBB permeability were shown. In particular, diversity of gut microbiota was altered (30 mg/kg/day q-value<0.05), showing increased population of Lactobacillus species. (30 mg/kg/day 411%; 100 mg/kg/day 1040%). Conclusions: KRG administration showed the Lactobacillus dominance in the gut microbiota. Improvement of AD pathology by KRG can be medicated through gut-brain axis in mice model of AD.

• 한국의류학회지
• /
• 제46권5호
• /
• pp.805-826
• /
• 2022

This study explored the process by which consumers purchase products from small fashion business owners via online and mobile channels. In addition, group types were classified given that the purchasing process depends on the consumers' life cycle. The consumer focus group interview (FGI) was conducted on 18 participants that were divided into six groups by age, work, and children. Results revealed that first, consumer journey comprised four stages. Factors influencing need recognition were "attention to information of social media influencer," "attention to information of affiliated groups," and "repeated advertising of SME products/brands." For information searching, "exploring purchase reviews," "environment for mobile shopping information exploration," and "continuous product tracking" were important factors. Purchasing and shopping stages were affected by "price-free, improvised purchase decision" and "convenient mobile payment system and point benefits." After the purchase, "active sharing and repeated purchase when satisfied" and "blocking relationships when dissatisfied" occurred. Second, six consumer groups based on the fashion life cycle are the "Platform lover," "Influencer follower," "Trust builder," "Novelty seeker," "Convenience seeker," and "New designer supporter." Ultimately, small business owners can develop the process of planning and selling fashion products more efficiently.

• 한국의류학회지
• /
• 제46권3호
• /
• pp.545-563
• /
• 2022

Metaverse is a digitally generated world beyond the physical realm; many fashion brands are launching virtual stores in Metaverse. This study explores the cases of flagship stores of fashion brands in Metaverse to understand the peculiarity of Metaverse retailing. This study selected four flagship stores of fashion brands launched on ZEPETO, the largest Metaverse platform in Korea. The characteristics of Metaverse retailing used for case analysis were store (store credibility, servicescape, ease of use), product (content, demos, incentives), social factor (store personnel, store customers), and entertainment (events, games, free gifts). The results illustrate that a transaction system linked to reality could not be established due to technical limitations; it was difficult to obtain specific product information, such as the color, size, and fabric. However, all four fashion brands overwhelmed the traditional retail channels in terms of providing various spatial experiences by operating their virtual stores in global cities related to the heritage and identity of each brand. Furthermore, fashion brands can convey a sense of deviation and fantasy to consumers by delivering unique entertainment activities in Metaverse that they cannot easily provide in real life.

• 한국전기전자재료학회논문지
• /
• 제35권2호
• /
• pp.119-128
• /
• 2022

Recent advancement of Internet of Things (IoT) and energy harvesting technology enable realization of flexible thermoelectric energy harvester (f-TEH), with technological prowess for use in biomedical monitoring system integrated applications. To expand a flexible thermoelectric energy harvesting platform, the f-TEH must be required for optimized flexible thermoelectric materials and device structure. In response to these demands related to thermoelectric energy harvesting, many research groups have investigated various f-TEHs applied as a power source for wearable electronics. As a key member of the f-TEH, film-based f-TEHs possess significant applicability in research to realize self-powered wearable electronics, owing to their excellent flexibility, low thermal conductivity, and convenient fabrication process. Thus, based on the rapid growth of thermoelectric film technology, this review aims to overview comprehensively the f-TEH made of various inorganic/organic thermoelectric materials including developed fabrication methods, high thermoelectric performance, and wide-range applications.

• International Journal of Contents
• /
• 제18권2호
• /
• pp.47-57
• /
• 2022

e-Learning content can be defined as digital content to achieve educational goals. Since it is an educational material that can be distributed in offline, online, and mobile environments, it is important to create content that meets the learner's education environment and educational goals. In particular, if the learner is a public official, the vision, philosophy, and characteristics of each local government must reflect. As non-face-to-face online education expands further due to the COVID-19 pandemic, local governments that have relied on onsite education in the past urgently require developing strong basic competency education and special task competency content that reflect regional characteristics. Such e-learning content, however, hardly exists and the ability to independently develop them is also insufficient. In this circumstance, this case study describes the process of self-production of e-learning content suitable for Busan's characteristics by the Human Resource Development (HRD) Institute of Busan City, a local government. The field of instructional design and instructional technology is always evolving and growing by blending technological innovation into instructional platform design and adapting to the changes in society. Busan HRD Institute (BHI), therefore, tried to implement blended learning by developing content that reflected the recent trend of micro-learning in e-learning through a detailed analysis. For this, an e-learning content developer with certain requirements was selected and contracted, and the process of developing content through a collaboration between the client and developer was described in this study according to the ADDIE model of Instructional Systems Development (ISD).

• 한국비블리아학회지
• /
• 제33권3호
• /
• pp.179-203
• /
• 2022

본 연구는 국가오픈액세스플랫폼(AccessON)의 개인 연구저작물 리포지터리인 Self Archiving과 학회의 Journal Repository 서비스의 경제적 가치측정을 목적으로 수행되었다. 문헌조사와 서비스 수혜자 및 관계자 15명과의 심층면담, 국내 연구자 1,313명을 대상으로 한 설문조사를 토대로 가치 측정에 필요한 데이터를 수집하였다. Self Archiving의 가치는 시간가치법을 적용하여 연구자 개인의 연간 절감 시간가치를 측정하였다. 국내 연구자들의 실제 학술활동에 기반하여 연구자 시간당 인건비, 국내생산 OA 논문 편수 등과 같은 요소들을 측정한 후, 연도별 이용 목표치를 토대로 총 수요를 추정하여 총 가치를 산출하였다. Journal Repository는 시장유추법을 적용하여, 상용 서비스의 객단가를 분석하고 이를 토대로 절감비용을 산출하였다. 분석결과, 총 사업기간 8년 동안 Self Archiving의 가치는 1억 450만 원, Journal Repository는 312억 원으로 산출되었다. 두 서비스의 총 가치는 8년간 총 313.5억 원, 연평균 390억 원으로 추정되었다. OA 환경 구축을 위한 핵심 전략인 개인 및 학회 리포지터리 서비스의 경제적 가치를 핵심 수혜자 관점에서 실증적으로 추정했다는 데서 본 연구의 의의를 찾을 수 있다.

• International Journal of Computer Science & Network Security
• /
• 제22권12호
• /
• pp.37-50
• /
• 2022

Modern supply chains include multiple activities from collecting raw materials to transferring final products. These activities involve many parties who share a huge amount of valuable data, which makes managing supply chain systems a challenging task. Current supply chain management (SCM) systems adopt digital technologies such as the Internet of Things (IoT) and blockchain for optimization purposes. Although these technologies can significantly enhance SCM systems, they have their own limitations that directly affect SCM systems. Security, performance, and scalability are essential components of SCM systems. Yet, confidentiality and scalability are one of blockchain's main limitations. Moreover, IoT devices are lightweight and have limited power and storage. These limitations should be considered when developing blockchain-based IoT-SCM systems. In this paper, the requirements of efficient supply chain systems are analyzed and the role of both IoT and blockchain technologies in providing each requirement are discussed. The limitations of blockchain and the challenges of IoT integration are investigated. The limitations of current literature in the same field are identified, and a secure and scalable blockchain-based IoT-SCM system is proposed. The proposed solution employs a Hyperledger fabric blockchain platform and tackles confidentiality by implementing private data collection to achieve confidentiality without decreasing performance. Moreover, the proposed framework integrates IoT data to stream live data without consuming its limited resources and implements a dualstorge model to support supply chain scalability. The proposed framework is evaluated in terms of security, throughput, and latency. The results demonstrate that the proposed framework maintains confidentiality, integrity, and availability of on-chain and off-chain supply chain data. It achieved better performance through 31.2% and 18% increases in read operation throughput and write operation throughput, respectively. Furthermore, it decreased the write operation latency by 83.3%.

• 국제초고층학회논문집
• /
• 제11권4호
• /
• pp.347-362
• /
• 2022

Current vibration serviceability assessment criteria for wind-induced vibrations in tall buildings are based largely on human 'perception' thresholds which are shown not to be directly translatable to human 'acceptability' of vibrations. There is also a considerable debate about both the metrics and criteria for vibration acceptability, such as frequency of occurrence or peak vs mean vibration, and how these might vary with the nature of the vibration. Furthermore, the design criteria are necessarily simplified for ease of application so cannot account for a range of environmental, situational and human factors that may enhance or diminish the impact of vibrations on serviceability. The dual-site VSimulators facility was created specifically to provide an experimental platform to address gaps in understanding of human response to building vibration. This paper considers how VSimulators can be used to inform general design guidance and support design of specific buildings for habitability, in terms of vibration, which allow engineers and clients to make informed decisions with regard to sustainable design, in terms of energy and financial cost. This paper first provides a brief overview of current vibration serviceability assessment guidelines, and the current understanding and limitations of occupants' acceptability of wind-induced motion in tall buildings. It then describes how the dual-site VSimulators facility at the Universities of Bath and Exeter can be used to assess the effects of motion and environment on human comfort, wellbeing and productivity with examples of how the facility capabilities have been used to provide new, human experience based experimental research approaches.

• 커뮤니케이션학 연구
• /
• 제20권1호
• /
• pp.43-68
• /
• 2012

통일은 방송이 우리 사회에서 지향해야 할 중요한 가치이며, 방송은 통일 이념을 실천하기 위하여 다양한 노력을 기울일 의무가 있다. 이러한 관점에서 방송이 통일문제에 있어 다양한 프로그램을 제공하고, 프로그램의 질적 향상을 위해 노력하는 작업은 중요하다. 이에 본 연구는 2000년대 초반부터 지난 10년간 국내 방송의 북한 및 통일관련 정규 프로그램인 KBS의 <남북의 창>과 MBC의 <통일전망대>를 분석하여 방송 프로그램의 특징과 차이를 살펴보았다. 특히 분석 대상이 되는 2001년부터 2010년까지의 방송 시기를 정권별로 세 개의 시기로 구분하여 아이템의 수, 보도형식과 주제 등이 방송사 간, 정권별로 차이가 있는지 분석하였다. 연구결과, 통일 프로그램에서 정부의 대북정책이나 남북 관계 등의 환경에 의해 정권별로 아이템의 형식과 주제가 차이가 나타나는 것을 확인할 수 있었다. 이것은 방송사 스스로 통일 프로그램에 대한 역할 정의 및 실천을 하지 못하고 있음을 보여준다. 국내 통일관련 방송이 상당부분 외부적 요인에 의해 좌우되고 있는 현실을 감안할 때, 통일관련 방송 프로그램에 관한 규제적 토대마련과 관심을 일깨울 기초적 작업은 향후에도 매우 필요하다 하겠다.