• The Korea Journal of Herbology
• /
• v.32 no.1
• /
• pp.69-74
• /
• 2017

Objectives : This study aimed to investigate the effects of Angelicae sinensis Radix on longitudinal bone growth rate in rats. We have screened traditional medicinal herbs to develop the longitudinal bone growth stimulator by well-established rat model. A. sinensis was identified as one of the effective herbs in the screening process. Methods : Adolescent female rats were administered A. sinensis at doses of 30 mg/kg and 300 mg/kg for 10 consecutive days. To observe the rate of longitudinal bone growth, tetracycline was injected intraperitoneally on day 8 to stain a fluorescent band on the anew formed bone. To elucidate the mode of action, we observed insulin-like growth factor-1 (IGF-1) and bone morphogenetic protein-2 (BMP-2) expression after A. sinensis administration in growth plate. Results : In the 300 mg/kg A. sinensis group, the length between the proximal endpoint of the tetracycline label and the division line between growth plate and bone was significantly increased compared with vehicle-treated control group. Height of the proximal tibial growth plate was higher in the A. sinensis group compared with control group. A. sinensis also upregulated the expressions of IGF-1 and BMP-2 in the proliferative zone and hypertrophic zone of the proximal tibial growth plate. Conclusions : A. sinensis increases longitudinal bone growth rate in rats. According to immunohistochemistry, A. sinensis increases local IGF-1 and BMP-2 expressions in the growth plate which can be considered as direct stimulation of GH on the local growth plate.

• Proceedings of the Computational Structural Engineering Institute Conference
• /
• 2005.04a
• /
• pp.592-600
• /
• 2005

Ship have cutout inner bottom and girder and floor etc. Ship's structure is used much, and structure strength must be situated, but establish new concept when high stress interacts sometimes fatally the area. There is no big problem usually by aim of weight reduction, a person and change of freight, piping etc.. Because cutout's existence grow up in this place, and elastic buckling strength by load causes large effect in ultimate strength. Therefore, stiffened perforated plate considering buckling strength and ultimate strength is one of important design criteria which must examine when decide structural concept at initial design. Therefore, md, reasonable buckling strength about stiffened perforated plate need to ultimate strength limited design . Calculated ultimate strength varied several web height and cutout's dimension, and thickness in this investigated data. Used program(ANSYS) applied F.E.A code based on finite element method

• Proceedings of the Korean Institute of Building Construction Conference
• /
• 2015.11a
• /
• pp.189-190
• /
• 2015

Slim Floor construction method has to increase the available surface area thereby reducing the depth beams and slab. In addition, In this study compostie beam assembly of plates, square-shape steel pipe and deck plate. So workabiltiy is superior to the upper concrete possible without formwork. In the present study is strength test in progress in development slim floor composite beam used plate and perforated square shape steel pipe and obtained anlysis and conclustion of the experimental results.

• Proceedings of the KSME Conference
• /
• 2001.06d
• /
• pp.546-552
• /
• 2001

The heat transfer and flow measurements on a pedestal encountered in chip cooling. A uniform wall temperature boundary condition at the plate surface and on a pedestal was created using shroud method. Liquid crystal was used to measure the plate surface temperature. The jet Reynolds number (Re) ranges from 11,000 to 50,000, the dimensionless nozzle-to-surface distance (L/d) from 2 to 10, and the dimensionless pedestal diameter-to-height (H/D) from 0 to 1.0. The results show that the Nusselt number distributions at the near the pedestal exhibit secondary maxima at $r/d{\cong}1.0\;and\;1.5$. The formation of the secondary maxima is attributed to an create in the vortex by the pedestal.

• Transactions of the Korean Society of Automotive Engineers
• /
• v.10 no.1
• /
• pp.9-16
• /
• 2002

The particles velocity in the instantaneous flow field and velocity change of particles along the jet centerline for various particle diameter in a circular turbulent impingement jet are investigated by using particle image velocimetry(PIV) and an equation of particle motion simplified by terms of inertia forces, drag and gravitational force. The jet Reynolds number was 3300 and 8700, and glass beads of 30,58 and 100$\mu$m in diameter were used. The PIV results show that the direction and size of velocity depends not only on the number density of particle but also on the particle momentum. The results obtained form calculation suggest that the particle velocity near the first impingement region deviated from local air velocity, which accords well with the PIV results. The rebound height of particle increase with the particle diameter. In the second-impingement, particle velocities increased sluggishly with Re=3300 but particle velocities uniformed with Re=8700 in stagnation region.

• Transactions of the Korean Society for Noise and Vibration Engineering
• /
• v.24 no.4
• /
• pp.332-338
• /
• 2014

Experimental study is conducted for investigating the characteristics of friction-induced noise with respect to the variation of system geometry. In this study, a vertically fixed rod is in contact with the reciprocating plate which is controlled by the step motor. Friction noise is generated during the reciprocating motion due to the frictional contact between the plastic pin and the aluminum plate. The frequencies of the friction noise are changed when the height of the rod varies. However, it is found that the vibration modes involved in the friction noise are not changed. It implies that the unstable modes remain unstable regardless of the change of the system geometry, and thus, there are the certain mode shapes which are likely to produce friction noise.

• Journal of the Korean Society of Visualization
• /
• v.13 no.3
• /
• pp.20-23
• /
• 2015

In this experiment, a heterogeneous droplet consisted of de-ionized water and olive oil was made through two 31G injection needles. The injection flow rate was $50{\mu}{\ell}/min$ and the droplet size was 2 mm. The droplet was impinged onto a sapphire plate which was heated up to $300^{\circ}C$ by a heater. Two high speed cameras were used for visualization, and the frame rate was 20,000 fps. A 150W metal halite lamp was used for illumination. The dropping height was fixed to 20 mm and the corresponding Weber number was 10.6 based on water. Due to different boiling points of two liquids, partial boiling features of heterogeneous droplet was observed. At the Leidenfrost condition, micro explosion phenomenon has occurred.

• Journal of Mechanical Science and Technology
• /
• v.16 no.4
• /
• pp.501-511
• /
• 2002

This paper presents a study of the effect of rolling temperature, roll gap (pass height), initial specimen size and steel grades of specimens on the roll force in round-oval-round pass sequence by applying approximate method and verifications through single stand pilot rod rolling tests. The results show that the predicted roll forces are in good agreement with the experimentally measured ones. The approximate model is independent of the change of roll gap, specimen size and temperature. Thus, the generality of the prediction methodology employed in the approximate model is proven. This study also demonstrates that Shida's constitutive equation employed in the approximate model needs to be corrected somehow to be applicable for the medium and high carbon steels in a lower temperature interval (700∼900$\^{C}$).

• Journal of Welding and Joining
• /
• v.31 no.1
• /
• pp.21-25
• /
• 2013

Aluminum alloy, Al5083-O, is one of candidate materials for the LNG storage tank, because of its excellent weldability, cryogenic characteristics, and corrosion resistance. The good weldability of Al5083-O is very important in LNG storage tank manufacturing. In this study, high current metal inert gas(MIG) welding process was used to get one pass welding of thick plate aluminum alloy. Bead on plate(BOP) welding was performed to evaluate the effect of welding conditions on the height of bead and depth of penetration. The optimum welding conditions were derived to get one pass welding of the thickness of 14.5mm. The mechanical properties of the welded joint were evaluated. The cross-sectional macro test, tensile test, and bending test satisfied the class rule.

• Proceedings of the Korean Society for Technology of Plasticity Conference
• /
• 2005.10a
• /
• pp.444-447
• /
• 2005

In recent industry, according to pursuit the miniaturization and high-precision of machine part with development of new technology as If, BT the development of mold manufacturing technology for mass production is accompanied. In this study, after executing the injection molding process of micro structure on the plate which the aspect ratio is 10, the characteristic of each molding condition is investigated by observing the filling height.