• Journal of Microbiology and Biotechnology
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• 제34권5호
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• pp.1003-1016
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• 2024

This study explores the potential of plant-based decellularization in regenerative medicine, a pivotal development in tissue engineering focusing on scaffold development, modification, and vascularization. Plant decellularization involves removing cellular components from plant structures, offering an eco-friendly and cost-effective alternative to traditional scaffold materials. The use of plant-derived polymers is critical, presenting both benefits and challenges, notably in mechanical properties. Integration of plant vascular networks represents a significant bioengineering breakthrough, aligning with natural design principles. The paper provides an in-depth analysis of development protocols, scaffold fabrication considerations, and illustrative case studies showcasing plant-based decellularization applications. This technique is transformative, offering sustainable scaffold design solutions with readily available plant materials capable of forming perfusable structures. Ongoing research aims to refine protocols, assess long-term implications, and adapt the process for clinical use, indicating a path toward widespread adoption. Plant-based decellularization holds promise for regenerative medicine, bridging biological sciences with engineering through eco-friendly approaches. Future perspectives include protocol optimization, understanding long-term impacts, clinical scalability, addressing mechanical limitations, fostering collaboration, exploring new research areas, and enhancing education. Collectively, these efforts envision a regenerative future where nature and scientific innovation converge to create sustainable solutions, offering hope for generations to come.

• Nuclear Engineering and Technology
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• 제52권2호
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• pp.397-416
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• 2020

Investigations of the commercial aircraft impact effect on nuclear island infrastructures have been drawing extensive attention, and this paper aims to perform the safety assessment of Generation III nuclear power plant (NPP) buildings subjected to typical commercial aircrafts crash. At present Part II, based on the verified finite element (FE) models of aircrafts Airbus A320 and A380, as well as the NPP containment and auxiliary buildings in Part I of this paper, the whole collision process is reproduced numerically by adopting the coupled missile-target interaction approach with the finite element code LS-DYNA. The impact induced damage of NPP plant under four impact locations of containment (cylinder, air intake, conical roof and PCS water tank) and two impact locations of auxiliary buildings (exterior wall and roof of spent fuel pool room) are evaluated. Furthermore, by considering the inner structures in the containment and raft foundation of NPP, the structural vibration analyses are conducted under two impact locations (middle height of cylinder, main control room in the auxiliary buildings). It indicates that, within the discussed scenarios, NPP structures can withstand the impact of both two aircrafts, while the functionality of internal equipment on higher floors will be affected to some extent under impact induced vibrations, and A380 aircraft will cause more serious structural damage and vibrations than A320 aircraft. The present work can provide helpful references to assess the safety of the structures and inner equipment of NPP plant under commercial aircraft impact.

• Transactions on Control, Automation and Systems Engineering
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• 제3권4호
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• pp.250-256
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• 2001

This paper deals with a design problem of a decentralized controller with a strongly connected two-input two-output multivariable system. To this end, we present a classical design approach which consists of two main steps: one is to decompose the multivariable plant into two single-input single-output systems by means of the Individual Channel Design (ICD) concept, the other is to design controller of each channel by the Coefficient Diagram Method (CDM) so that it satisfies, especially, time domain specifications such as settling time, overshoot etc.. A design procedure was proposed and then was applied to a 2$\times$2 hot rolling mill plant. Simulation results showed that the proposed method has excellent control performances.

• Journal of Advanced Marine Engineering and Technology
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• 제23권5호
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• pp.670-678
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• 1999

Heat recovery steam generator(HRSG) is a principal component of the combined cycle power plant (CCPP) which utilizes the waste energy of the gas turbine exhaust gas. A design of the HRSG is a keypoint to achieve high cycle efficiency with competitive cost. This paper presents a brief review on the design of a HRSG which covers the basic design parameters and their effects on the performance and the investment cost. Finally the concept of the optimum design point is presented according to the selection of a pinch point temperature difference and a steam pressure as an illustrated case.

• Nuclear Engineering and Technology
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• 제35권2호
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• pp.121-132
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• 2003

To reduce the construction cost and enhance the safety of sodium cooled liquid metal reactors, various kinds of new design concepts were evaluated using the KALIMER operation condition. The required equipment sizes were set for plant electricity output to be similar to that of KALIMER. The evaluations were made focusing on the plant performance and implementation practicality. Each design concept was evaluated for the concept itself and design impacts to interfacing systems. Through the evaluation of the concepts, it was found that the most favorable design concept is the integrated steam generator with forced convection using lead bismuth as the intermediate heat transfer fluid between the primary sodium tube and feed water/steam tube in the steam generator.

• KEPCO Journal on Electric Power and Energy
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• 제2권3호
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• pp.415-419
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• 2016

As the need for clean coal technology has grown, so has the global research and development efforts into integrated gasification combined cycle (IGCC) plants. An IGCC plant couples a gas turbine to a gasification block. Various technical and economic problems exist in designing such a system. One such problem is the difficulty in realizing economies of scale because the single-train flow capacity of commercial IGCC synthetic gas turbine plants is limited; the capacity does not exceed a net power rating of 300 MW. To address this problem, this study modeled and simulated a synthetic gas turbine with the goal of evaluating the feasibility of a 500 MW or larger IGCC plant. First, a gas turbine with the best output and efficiency was chosen for use with natural gas. The turbine was modeled using GateCycle (a simulation tool), and the integrity of the model validated by comparing the result to the design value. Next, off-design modeling was carried out for a gas turbine with synthetic gas based on its on-design model, and the result was compared with the study result of the gas turbine manufacturer. The simulation confirmed that it is possible to create a large capacity IGCC plant by undertaking the remodeling of a gas turbine designed to use natural gas into one suitable for synthetic gas.

• 신재생에너지
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• 제5권4호
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• pp.39-43
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• 2009

The variation of inflow at stream and hydrologic performance for small scale hydro power(SSHP) plants due to climate change have been studied. The model, which can predict flow duration characteristic of stream, was developed to analyze the variation of inflow caused from rainfall condition. And another model to predict hydrologic performance for SSHP plants is established. Monthly inflow data measured at Andong dam for 32 years were analyzed. The existing SSHP plant located in upstream of Andong dam was selected and analyzed hydrologic performance characteristics. The predicted results from the developed models show that the data were in good agreement with measured results of long term inflow at Andong dam and the existing SSHP plant. Inflow and ideal hydro power potential had increased greatly in recent years, however, these did not lead annual energy production increment of existing SSHP plant. As a results, it was found that the models represented in this study can be used to predict the primary design specifications and inflow of SSHP plants effectively.

• 한국농업기계학회:학술대회논문집
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• 한국농업기계학회 1996년도 학술발표대회 논문집
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• pp.17-21
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• 1996

• 대한조선학회논문집
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• 제40권6호
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• pp.20-29
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• 2003

When Arctic offshore development in the 1970's first led to the consideration of ice capable tankers, there was a high level of uncertainty over design requirements for both safety and ship performance. Also here was a lack of reliable methods to evaluate design proposals. Since that time, improved understanding of the ice environment has raised the confidence of design specifications. Parallel developments have resulted in a suite of engineering tools for ship performance evaluation at the design stage Recent development of offshore and near shore oil and gas reserves in several countries together with economic studies of increased transportation through the Russian Arctic has newly introduced the interest in ice capable tanker design. in response, Samsung Heavy Industries (SHI) applied its experience in tanker design and construction to the design of a specialized tanker with ice capability. SHI produced two prototype hull designs for further study. The performance of both hulls and of the propellers was evaluated at the Institute for Marine Dynamics (IMD) in St. John's, Newfoundland This paper discusses the development of the design, describes the model experiments to determine performance and variations, and presents the results.

• 한국건설관리학회논문집
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• 제20권2호
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• pp.28-36
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• 2019

국내 신형원전 APR1400 (Advanced Power Reactor 1400MW)은 총 사업비 8조 6천억원, 사업기간 10년 이상이 소요되는 대형 국가기반시설이며, 60년 이상 운영되어 국가경제 및 국민의 안전에 밀접한 영향을 끼친다. 또한 총 사업부지 217만$m^2$내 20개 이상의건물 및 구조물로 구성되어 있으며, 건설에 필요한 전체도면은 약 6만5천장에 이른다. 이러한 대형시설의 설계를 위해서는 설계의도를 명확히 규정하여 일관성 있게 설계가 진행될 수 있는 일종의 가이드라인 역할을 하는 설계기준이 필수적이다. 이를 위해 설계기준(Design Bases)을 반영한 설계기준문서(Design Bases Document 또는 Drawing, DBD)를 작성하여, 설계 일관성 및 도면간의 일치성을 유지하고 있다. 하지만 설계기준은 원전 전체 설계에 큰 틀이 되는 중요한 개념임에도 불구하고 각 분야 전문가들에 의해 문서기반(2차원) 및 파편적으로 관리되다보니 후속설계에 정확히 반영되는데 한계가 있었다. 따라서 본 연구에서 시설정보 활용성을 높이기 위해 3차원 정보모델인 BIM (Building Information Model)과 Algorithm-aided BIM을 활용하여, 원전의 최소단위 공간인 실(Room)을 기반으로 한 3차원 설계기준 관리하는 시스템을 개발하였다. 이를 위해 설계기준정보층(DBIL)개념을 도입하였으며, 시뮬레이션을 통해 각 DBIL별 설계기준 속성 및 설계요소 데이터가 연동됨을 확인하였으며, DBIL에 연계되는 벽, 바닥, 문, 관통부 등을 정상적으로 추출하였다.