• Title/Summary/Keyword: Pilot Unit

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Statistical Optimization for Monacolin K and Yellow Pigment Production and Citrinin Reduction by Monascus purpureus in Solid-State Fermentation

  • Jirasatid, Sani;Nopharatana, Montira;Kitsubun, Panit;Vichitsoonthonkul, Taweerat;Tongta, Anan
    • Journal of Microbiology and Biotechnology
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    • v.23 no.3
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    • pp.364-374
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    • 2013
  • Monacolin K and yellow pigment, produced by Monascus sp., have each been proven to be beneficial compounds as antihypercholesterolemic and anti-inflammation agents, respectively. However, citrinin, a human toxic substance, was also synthesized in this fungus. In this research, solidstate fermentation of M. purpureus TISTR 3541 was optimized by statistical methodology to obtain a high production of monacolin K and yellow pigment along with a low level of citrinin. Fractional factorial design was applied in this study to identify the significant factors. Among the 13 variables, five parameters (i.e., glycerol, methionine, sodium nitrate, cultivation time, and temperature) influencing monacolin K, yellow pigment, and citrinin production were identified. A central composite design was further employed to investigate the optimum level of these five factors. The maximum production of monacolin K and yellow pigment of 5,900 mg/kg and 1,700 units/g, respectively, and the minimum citrinin concentration of 0.26 mg/kg were achieved in the medium containing 2% glycerol, 0.14% methionine, and 0.01% sodium nitrate at $25^{\circ}C$ for 16 days of cultivation. The yields of monacolin K and yellow pigment were about 3 and 1.5 times higher than the basal medium, respectively, whereas citrinin was dramatically reduced by 36 times.

Design of A Stateless Minimum-Bandwidth Binary Line Code MB46d (Stateless 최소대역폭 2진 선로부호 MB46d의 설계)

  • Lee, Dong-Il;Kim, Dae-Young
    • Journal of the Korean Institute of Telematics and Electronics S
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    • v.35S no.10
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    • pp.11-18
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    • 1998
  • A binary line code, called MB46d, is designed by use of the BUDA(Binary Unit DSV and ASV) cell concept to retain the property of being runlength limited, DC tree, and with a power spectral null at the Nyquist frequency. This new code is a stateless line code with a simple encoding and a decoding rule and enables efficient error monitoring. The power spectrum and the eye pattern of the new line code are simulated for a minimum-bandwidth digital transmission system where the sinc function is used as a basic pulse. The obtained power null at the Nyquist frequency is wide enough to enable easy band-limiting as well as secure insertion of a clock pilot where necessary. The eye is also substantially wide to tolerate a fair amount of timing jitter in the receiver.

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Forecasting Cargo Traffic of Zarubino Port with O/Ds of Jilin Sheng in China (중국 지린성 대상의 자루비노항 경유물동량 전망)

  • An, Guo Shan;Koh, Yong Ki;Noh, Jin Ho
    • International Commerce and Information Review
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    • v.18 no.1
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    • pp.81-105
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    • 2016
  • Recently, master plan on the Far East three provinces in China as well as the Russian Far East coupling with 'Eurasia Initiatives' of our government is doubling its importance. It should take advantage of Zarubino port for the hub of Eurasia Logistics Network. This study forecasts the volume demand and whether the expected items of cargo traffic of Zarubino port with O/Ds for the region including the Far East three provinces in China. Input data and the existing basic unit of Korea were utilized in order to overcome the absence of the relevant information to the region. It was derived by them confined to the industrial complex facility in Jilin Sheng on behalf of the Far East three provinces in China as a pilot study. Suitable for the transport sector as a basis for traditional traffic demand, four-step method for estimating the proposed modifications, complementing methodologies. This study is determined that the contribution to the implications on the region's logistics policies of our government has a commitment with raising awareness of the region's Logistics system.

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Screening of Spray-Dried K2CO3-Based Solid Sorbents using Various Support Materials for CO2 Capture

  • Eom, Tae Hyoung;Lee, Joong Beom;Baek, Jeom In;Ryub, Chong Kul;Rhee, Young Woo
    • KEPCO Journal on Electric Power and Energy
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    • v.1 no.1
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    • pp.115-120
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    • 2015
  • $K_2CO_3$-based dry regenerable sorbents were prepared by spray-drying techniques to improve mass produced $K_2CO_3-Al_2O_3$ sorbents (KEP-CO2P, hereafter), and then tested for their $CO_2$ sorption capacity by a $2,000Nm^3/h$ (0.5 MWe) $CO_2$ capture pilot plant built for Unit 3 of the Hadong thermal power station in 2010. Each of the sample sorbents contained 35 wt.% $K_2CO_3$ as the active materials with various support materials such as $TiO_2$, MgO, Zeolite 13X, $Al_2O_3$, $SiO_2$ and hydrotalcite (HTC). Their physical properties and reactivity were tested to evaluate their applicability to a fluidized-bed or fast transport-bed $CO_2$ capture process. The $CO_2$ sorption capacity and percentage utilization of $K_2CO_3$-MgO based sorbent, Sorb-KM2, was $8.6g-CO_2/100g$-sorbents and 90%, respectively, along with good mechanical strength for fluidized-bed application. Sorbs-KM2 and KT were almost completely regenerated at $140^{\circ}C$. No degradation of Sorb-KM by $SO_2$ added as a pollutant in flue gas was observed during a cycle test.

Design of a Warning System Using Radio Beacon Signal to Avoid Hazardous Area in VFR Mode (무선전파막을 이용한 시계 비행항공기의 비행위험지역 회피용 경보장치의 설계)

  • Kim, Yeon-Myung;Park, Dong-Young;Yun, Tae-Won;Hwang, Byong-Won
    • Journal of Advanced Navigation Technology
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    • v.8 no.2
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    • pp.98-104
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    • 2004
  • When a straight-in landing from an instrument approach using ILS or VOR/DME is not possible or desirable because of topographical reason or bad weather, a circling approach maneuver is initiated by the pilot to align the aircraft with a runway for landing. Visual contact with the runway is necessary while conducting a circle to land maneuver. This research is to develop a new warning system based on a convention marker system which alerts pilots to watch out for exceeding the circling approach area. The airborne system also uses the same receiver unit without any new installations. The objective of this research is to design and develop a Yagi antenna in a special form. The research includes computer simulations to determine the size of antenna radiation pattern and to compute an expected flight path in case of alarm to validate effectiveness of the system.

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Short-Term Clinical Effects of Robot-Assisted Gait Training Applied to Patients Undergoing Lower Extremity Surgery: A Pilot Study (하지 수술환자에게 적용한 로봇보조 보행훈련의 단기간 임상적 효과: 예비 연구)

  • Lee, Ha-Min;Kwon, Jung-Won
    • PNF and Movement
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    • v.20 no.2
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    • pp.295-306
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    • 2022
  • Purpose: This study aimed to investigate the effect of robot-assisted gait training on the active ranges of motion, gait abilities, and biomechanical characteristics of gait in patients who underwent lower extremity surgery, and to verify the effectiveness and clinical usefulness of robot-assisted gait training. Methods: This study was conducted on 14 subjects who underwent lower extremity surgery. The subjects participated in robot-assisted gait training for 2 weeks. The active ranges of motion of the lower extremities were evaluated, and gait abilities were assessed using 10-m and 2-min walk tests. An STT Systems Inertial Measurement Unit was used to collect data on biomechanical characteristics during gait. Spatiotemporal parameters were used to measure cadence, step length, and velocity, and kinematic parameters were used to measure hip and knee joint movement during gait. Results: Significant improvements in the active ranges of motion of the hip and knee joints (flexion, extension, abduction, and adduction) and in the 10-m and 2-min walk test results were observed after robot-assisted gait training (p < 0.05). In addition, biomechanical characteristics of gait, spatiotemporal factors (cadence, step length, and velocity), and kinematic factors (gait hip flexion-extension, internal rotation-external rotation angle, and knee joint flexion-extension) were also significantly improved (p < 0.05). Conclusion: The results of this study are of clinical importance as they demonstrate that robot-assisted gait training can be used as an effective intervention method for patients who have undergone lower extremity surgery. Furthermore, the findings of this study are clinically meaningful as they expand the scope of robot-assisted gait training, which is currently mainly applied to patients with central nervous system conditions.

Use of measuring gauges for in vivo accuracy analysis of intraoral scanners: a pilot study

  • Iturrate, Mikel;Amezua, Xabier;Garikano, Xabier;Solaberrieta, Eneko
    • The Journal of Advanced Prosthodontics
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    • v.13 no.4
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    • pp.191-204
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    • 2021
  • PURPOSE. The purpose of this study is to present a methodology to evaluate the accuracy of intraoral scanners (IOS) used in vivo. MATERIALS AND METHODS. A specific feature-based gauge was designed, manufactured, and measured in a coordinate measuring machine (CMM), obtaining reference distances and angles. Then, 10 scans were taken by an IOS with the gauge in the patient's mouth and from the obtained stereolithography (STL) files, a total of 40 distances and 150 angles were measured and compared with the gauge's reference values. In order to provide a comparison, there were defined distance and angle groups in accordance with the increasing scanning area: from a short span area to a complete-arch scanning extension. Data was analyzed using software for statistical analysis. RESULTS. Deviations in measured distances showed that accuracy worsened as the scanning area increased: trueness varied from 0.018 ± 0.021 mm in a distance equivalent to the space spanning a four-unit bridge to 0.106 ± 0.08 mm in a space equivalent to a complete arch. Precision ranged from 0.015 ± 0.03 mm to 0.077 ± 0.073 mm in the same two areas. When analyzing angles, deviations did not show such a worsening pattern. In addition, deviations in angle measurement values were low and there were no calculated significant differences among angle groups. CONCLUSION. Currently, there is no standardized procedure to assess the accuracy of IOS in vivo, and the results show that the proposed methodology can contribute to this purpose. The deviations measured in the study show a worsening accuracy when increasing the length of the scanning area.

Main Function, Management Difficulties and Activating Conditions of the Cooperative Child Care Sharing Center Based on Field Cases (현장 사례로 본 공동육아나눔터의 주요 기능과 운영상 문제 및 활성화 조건)

  • Lee, Seung-mie;Kim, Seon-mi
    • Journal of Family Resource Management and Policy Review
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    • v.26 no.1
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    • pp.59-73
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    • 2022
  • This qualitative study focused on the activation of cooperative child care sharing centers'. Eight centers nationwide were selected as example cases in accordance with region (large city, small and medium-sized city, county unit), opening time, operating institution, location, full-time care for dual-income children, and participation in the 2020 care community pilot project. Co-researchers visited each center together to observe the site and conducted in-depth interviews with the head of the center or dedicated staff using semi-structured questionnaires. Interview data were analyzed using triangle verification and transcribed : the data were then grouped into 12 categories and 34 subcategories. From this, the following three topics were derived: the main functions, operational difficulties, and activation conditions. In conclusion, four suggestions are made: 1. proper relationship with the Family center, the cooperative childcare sharing center, and the local care communities 2. activation plan through "solution of operational difficulties" 3. "extension" of the cooperative child care sharing center 4. the role of the Ministry of Gender Equality and Family, the Korea Institute for Healthy Family, local governments, and Family Centers.

Standardization of machining process for progressive press die (순차이송형 프레스 금형의 가공표준화)

  • Lee, S.M.;Lee, S.J.
    • Journal of the Korean Society for Precision Engineering
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    • v.10 no.2
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    • pp.114-125
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    • 1993
  • In the present study the newly developed CAD/CAM system is applied to the process of the molding design, machining for mini-sized and precise processive die, and the production of press-stamped parts. When the design of a die was completed by means of CAD, wire cut NC data were generated with the aid of a design drawing in the CAD system and then inputed into the wire cut machine, and with the aid of a hole chart which had been made for this purpose, all the data were classified into the categories of CNC milling, jig boring, jig grinding, and machine center, and then developing a program of generating NC data, errors in process were reduced and programming time was shortened. The program was developed by using Autolisp language which was built-in the CAD, and realizing the intergation of designing a die, generating and processing NC data directly by a designer, designing time and machinery processing time were shorted. And the traditionally required working time for design. NC program required 6 days of work becomes 4 days of work by using the developed CAD/CAM system so that the efficiency shows 150% of the reduction working time. The prpgram of the design of the automation a progressive die mold was developed in the PC-Class Autocad system, therefore development expense could be reduced, and the integration of the CAD/CAM of the progressive die mold with the standard DB being built could be realized.

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Determinants of pay satisfaction of dental employees (치과 의료 기관 직원의 임금만족에 영향을 미치는 요인)

  • Bak, Yeong-Chan;Jeong, Seong-Hyeon;Bak, Seong-Nam;Kim, Eui-Jeong;Shin, Hosung
    • The Journal of the Korean dental association
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    • v.54 no.5
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    • pp.374-383
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    • 2016
  • The purpose of this study is to analyze the determinants of pay satisfaction of dental employees. The questionnaire used in this study consists of personal characteristics, characteristics of workplace, administration of pay, Pay satisfaction questionnaire (PSQ). PSQ was translated, and backward translation into korean was implemented. A pilot test was conducted with 25 dental employees to complete the questionnaire. Survey was conducted from February to July in 2015, receiving 323 valid responses. Anova or t-test was conducted with categorized characteristics, by calculating pay satisfaction scores. Principal factor analysis which is an exploratory factor analysis was conducted to investigate the consistency of pay satisfaction. Multiple regression analysis was conducted to investigate how much effect the variables have on pay satisfaction. The result of principal factor analysis showed that pay satisfaction consists of 3 factors which are 'paying system', 'pay level', 'benefits'. 'Pay raise' which was one of 4 factors of original PSQ was not the factor of pay satisfaction of dental employees. The result of analysis of characteristics showed that the scores of paying system between dental clinic and dental hospital had significant difference. The result of multiple regression analysis showed tendencies pay satisfaction increases when age and monthly income increases and whole career and the number of unit chairs decreases. Increasing the autonomy of employees and simplification of paying system would improve pay satisfaction efficiently. When age increases, the pay level increases because of the seniority-based pay structure, and this leads to the higher satisfaction. The higher amount of pay leads to higher satisfaction. The expectation over pay increases relatively higher than the increase of pay level and this leads to the less satisfaction. When the number of unit chairs is fewer, the workplace is smaller, so the employees have more autonomy, and this leads to higher satisfaction.

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