• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.3
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• pp.748-752
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• 2006

Wei symptom(?證) is symptom that reveals muscle relaxation without contraction and muscle relaxation occurs in the lower or upper limb, in severe case, leads to death. This is the clinical report about the Wei symptom(?證)-patient doubt as Transverse Myelitis and Conversion Disorder. The patient was treated by acupuncture, moxibustion, herb medication(十全大補湯), electriccal stimulation theraphy, Bee Venom acupuncture, and had significant improvement in Wei symptom(?證). these results suggest the surface temperature differ remarkably from before being treated. The temperature is measured by using Digital Infrared Thermal Imaging(DITI). The results suggest that oriental medicare is an effective treatment for Wei symptom. We expected that therapeutic value of treatment of both leg Paralysis in the oriental medicine will be higher if more clinical studies and researches are accomplished.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.6
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• pp.1068-1076
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• 2010

This study was to establish and evaluate international educational program for foreign traditional medicine students with traditional Korean medicine in School of Korean Medicine, Pusan National University, and discussed prerequisite requirements for international educational program. The Introduction to Traditional Korean Medicine (TKM) was constructed with Korea and TKM, Understanding TKM, Future of TKM, Clinical Skills (lecture and practice), Clinical practice (observation), Field trip, and others. The overall assessment was concluded as excellent (91.7%). The prerequisite requirements for planning and operating educational program, and key points for the success of international program were discussed. And the necessity of Center for International Educational of Traditional Medicine was described. This study can be used as a reference manual for globalization of TKM education and proposal for making policy on TKM.

• Proceedings of the IEEK Conference
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• 2006.06a
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• pp.859-860
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• 2006

We developed a cuffless and noninvasive measurement technique of blood pressure using tonometric pressure sensor. With observation that the maximum value of pulse pressure is not obtained at mean arterial pressure(MAP), we have figured out MAP based on the physiological characteristic including the elasticity of wrist tisse. Detecting only one part of the body and using only one device are quite advantageous over other BP measurement techniques. Our technique makes new way for the cuffless BP measurement.

• Journal of the Korean Society of Food Science and Nutrition
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• v.28 no.2
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• pp.371-377
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• 1999

In order to evaluate the antimicrobial function of natural herb extracts as antimicrobial agent or packaging material for the preservation of foods and greenhouse produce, the water extract of chopi (Zanthoxylum piperitum DC.) was prepared and its antimicobial activity was determined. In the paper disk test its antimicrobial activity was increased in proportion to its concentraion. The growth of microorganisms was completely inhibited above 500ppm of its concentration. It showed wide spectrum of thermal(40 to 180oC) and pH(4 to 10) stabilities. In the electronic microscopic observation(TEM and SEM) of microbial morphological change it showed to decrease the activation of physiological enzymes and to lose the function of cell membranes. Even in the activation test of galactosidase, it seemed to weaken the osmotic function of cell membranes remarkably in comparison with chloroform and its activation corresponded to 40~50% of toluene. Zanthoxylum piperitum DC. extract seemed to be an excellent antimicrobial for the inhibition of food borne microorganisms as well as the pre servation of greenhouse produces.

• Korean Journal of Veterinary Research
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• v.36 no.4
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• pp.967-972
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• 1996

A study was carried on histopathology of LUTD. Based on this study, it was noted that a plural number of factors and some genetic mechanisms are participating in onset of this disease, which should have to be studied further in future in omnidirections.

• Korean Journal of Microbiology
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• v.23 no.4
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• pp.248-251
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• 1985

An imperfect fungus recognized as a dermatophyte was isolated from soil samples and the macroscopic, microscopic and physiological characteristics were examined. From the comparisons of this isolate with the known species, the strain belonged to the genus Microsporum. She showed mant different characteristics from the related species, including colony color and shape, or number in a cell of macrocondium. This isolate was considered to be a novel species in the genus Microsporum. Therefore the name was given to her as Microsporum nigricans Yeeh sp. nov. because of dark blackish color from the macroscopic observation.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.1
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• pp.245-256
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• 2006

This research sought to survey oriental medicine diagnosis methods currently practiced, analyze their advantages and disadvantages, and work out clinical establish direction for oriental medicine diagnosis methods. Oriental medicine diagnosis methods currently practiced in the related circles are categorized into traditional Korean diagnosis methods and holistic auxiliary diagnosis methods. The traditional Korean diagnosis method focuses on treating diseases of traditional Korean health management methods which are based on the bodily self-viability capabilities according to the Orient's viewpoint of health. Under the diagnosis method, based on the cognition of maximizing the state of the bodily self-viability capabilities together with the characteristics of diseases, symptoms, pulse, first face-to-face patient observation, physical constitution, and life principle are managed according to form, color, pulse and symptom which divide the bodily viability capacities into inherent and acquired elements amid both elements interacting.

• Biomolecules & Therapeutics
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• v.7 no.3
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• pp.210-215
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• 1999

Nitric oxide (NO) can mediate numerous physiological processes, including vasodilation, neurotransmission, cytotoxicity, secretion and inflammatory response. The regulation of NO production by inducible NO synthase (iNOS) is considered to be the possible target of the development of anti-inflammatory agent, based on the observation that NO can activate cyclooxygenase, which results in the synthesis of prostaglandins. In an effort to screen new inhibitor of NO production from about 352 species of herbal extracts, we found 9 species with 50% or more inhibitory effect on NO production. Especially, the dose-dependent inhibition of NO production in lipopolysaccharide-treated macrophages by two of the herbal extracts (Artemisiae asiaticae Herba and Saussureae Radix) was due to the decrease in the expression of iNOS.

• Journal of Life Science
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• v.21 no.10
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• pp.1487-1493
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• 2011

E. tarda, a fish pathogen, can survive in seawater under relatively high salt conditions as well as in fish under physiological salt conditions. Bacterial growth under different salt concentrations may influence the expression of genes involved in bacterial structure and physiology. The growth rate of E. tarda culture in high salt (3.5% NaCl) was similar to that in low salt (1.0% NaCl, physiological salt concentration). Interestingly, the strain moved much faster in low salt conditions than in high salt conditions. Electron microscopic observation demonstrated that the bacterial cells grown in high salt had less or no flagellation. Obvious flagellation was observed in the parental strain E. tarda CK41 grown in low-salt condition. Two putative genes coding flagellin were identified in the E. tarda genome sequences. The amino acid sequence comparison of each gene revealed 93% identities. A flagellin gene was PCR amplified and cloned into a cloning vector. Using an E. coli protein expression system, a part of flagellin protein was overexpressed. Using the purified protein, an anti-flagellin antibody was raised in the rabbit. Immunoblot analyses with flagellin specific antibody demonstrated that E. tarda CK41 expressed falgellin in low salt conditions, which is consistent with the results seen in motility assay and microscopic observation. This is the first report of salt regulated flagella expression in E. tarda.

• Asian-Australasian Journal of Animal Sciences
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• v.14 no.7
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• pp.951-955
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• 2001

The behaviour of 6 Toggenburg and 6 Saanen female goats, grazing on natural vegatation in a modified sub-humid tropical environment of Kenya, was studied during the dry (January and February) and wet (April and May) seasons in 1997. The two exotic breeds grazed for 12 h daily. Observation on feeding, standing, lying and ruminating was done chronometrically at five minute intervals between 0600 and 1800 h. These grazing times were based on the current practice of small holder farmers. During the dry period, the average feeding, standing, lying and ruminating time per 12 h period for Saanens was 5.63, 4.57, 1.80 and 1.50 h respectively while that for Toggenburgs was 7.26, 3.21, 1.53 and 1.96 h, respectively. In the wet(Green) season, the mean feeding, standing, lying and ruminating time for Saanens was found to be 5.08, 4.63, 2.29 and 0.72, respectively.Toggenburgs spent more time feeding (p<0.05) than Saanens in both seasons. It was also observed that standing occured more often in Saanens than the Toggenburgs in the dry season. During the wet period, Saanens ruminated significantly longer than the Toggenburgs. The health status of the animals was determined by analyzing the respiratory frequency, heart rate, rectal temperature, hemoglobin, erythrocytes and leucocytes of the experimental animals. All the clinical and physiological parameters were within the normal physiological range of healthy goats. It was concluded that differences in the grazing behaviour of Saanens and Toggenburgs in the modified tropical environment of Kenya, do exist.