• Journal of Korean Biological Nursing Science
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• 제2권1호
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• pp.76-84
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• 2000

Recently, music therapy is widely used for various kinds of diseases. Music therapy has beneficial effects on emotional disorder and neuropsychiatric diseases in particular. This study was performed to evaluate the effect of singing on physiologic changes. We checked peripheral oxygen saturation and heart rate as indices of physiologic changes. The subjects were 19 control and 30 test group who were registered on the D welfare center for the elderly and agreed to join this study. They had been singing regularly for 6 months. The data were collected just before and after the singing. Data were analyzed with mean, t-test, and paired t-test using SPSS $PC^+$ program. The results were as follows: 1. Heart rate of the singing group decreased significantly after singing.(p<0.05) 2. Peripheral oxygen saturation of the singing group increased significantly after singing.(p<0.05) In conclusion, singing, a kind of aerobic exercise, has beneficial effects on cardiopulmonary system.

• Journal of Korean Biological Nursing Science
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• 제19권2호
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• pp.51-59
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• 2017

Purpose: The purpose of this study was to identify the retention effects of an individualized dietary education program for hemodialysis patients on diet knowledge, diet self-care compliance, and physiological indices, thus to find the most effective time period for re-education. Method: This study utilized one-group repeated pretest-posttest design. The participants were 52 hemodialysis patients in C hospital, Gyeonggi-Do. Data were collected at 4 and 12 weeks after the education from January through April 2016. Results: There was significant increases in diet knowledge even 12 weeks after the education (p= .007). Diet self-care compliance showed a significant increase at 4 weeks (p= .001), but a decrease at 12 weeks after the education. The level of blood natrium was significantly decreased between 4 and 12 weeks after the education (p= .006). The weight was significantly decreased at 12 weeks after the education. Conclusion: It has been identified that re-education for hemodialysis patients should be implemented between 4 and 12 weeks after education in order to maintain patients' diet self-care compliance, an ultimate aim of diet education. By helping them with their self-care compliance, the patients would maintain their physical and psychological function optimally, thus contributing to a better quality of life among hemodialysis patients.

• Journal of Korean Biological Nursing Science
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• 제9권2호
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• pp.105-117
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• 2007

Purpose: The purpose of this study was two folds: first, to identify the level of self care behavior of the hemodialysis patients and second, to find the correlation between the self care behavior and the physiologic indices. Method: The subjects were 52 hemodialysis patients, male and female, who have regularly received hemodialysis dialysis at the Dialysis Room in a leading teaching hospital, Seoul. The patients responded to the self care behavior questionnaires including their socio-demographic characteristics. The respondents have regularly recorded the self care log book. The physiologic indices, clinical characteristics related to the disease and hemodialysis were collected by the chart review. Result: The mean score of the self care behavior was 3.46. The mean score of the self care behavior on categories demonstrated as follows: medication 4.29, fistula management 4.13, management of physical problem 3.71, diet 3.28, exercise and rest 3.22, blood pressure and body weight management 2.97 and social adjustment 2.05 in order. Thirty patients managed discomfort of their fistula. Eleven patients took exercise for 0.5-1 hr/week. Thirty patients measured their body weight daily and thirty two measured their blood pressure daily. The score of self care behavior was significantly correlated with the mean weight gains between the dialysis sessions(r=-.312, p=.05). The mean weight gains between dialysis sessions was found to be high as the level of serum phosphorus and potassium increased(r=-.316, p=.05, r=-.465, p=.01). Conclusion: The result suggests that nursing intervention to the hemodialysis patients to improve self care behavior should be encouraged and further developed.

• Journal of Korean Biological Nursing Science
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• 제4권2호
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• pp.93-112
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• 2002

Recently, the number of the elderly has increased according to the improvement of socioeconomic status and the efficient medical care system. In spite of the development of medicine, the elderly suffers from the various health problems caused by weakness of musculoskeletal system, cardiopulmonary function and immunologic dysfunction. Regular rhythmic exercise program is known to be one of the effective tools to enhance the health condition in the elderly. However, there has been few studies to evaluate the comprehensive effects of rhythmic movement program on the elderly. This study was focused to evaluate the indices of cardiopulmonary function, life satisfaction, calcium, phosphorous, osteocalcin and deoxypyridinoline which are the essential factors of health problems in the elderly women. Twenty six subjects, aged between 68 and 72, who can do the ordinary activities and do not have cardiovascular dysfunction and mental disorder, participated in this study. They were divided into two groups: 13 in the experimental group and 13 in the control group. The experimental group participated in the rhythmic movement program at the welfare center located in G-city. The program were consisted of three sessions a week during 10 weeks. Each session had three parts: warming up(10 minutes), main exercise(40 minutes), finishing(10 minutes). Heart rate, blood pressure and peripheral arterial oxygen saturation were measured for the evaluation of cardiopulmonary function. Serum calcium, phosphorous, osteocalcin and urine deoxypyridinoline were measured as the indices of bony metabolism. Data were analyzed with mean, standard deviation, $x^2$-test, t-test, paired t-test using SPSS PC+ program. The results of this study were as follows. 1) Heart rate of the experimental group showed significant decrease following the rhythmic movement program. Peripheral arterial oxygen saturation of the experimental group showed significant increase following the program. 2) The degree of life satisfaction of the experimental group showed significant increase following the program. 3) Calcium showed significant decrease following the program but remained within normal range. There was no significant difference of phosphorous between two groups. 4) Osteocalcin, the index of bone formation, showed no significant change following the program, but significant increase in the experimental group comparing with the control group. 5) Deoxypyridinoline, the index of bone resorption, in urine of the experimental group showed significant decrease following the program. In conclusion, the rhythmic exercise program in the elderly showed the improvement of physiologic function and favorable effects on life satisfaction and bony metabolism. According to the above results, the regular rhythmic movement program can be strongly recommended for the improvement of health in the elderly women.

• Anatomy and Cell Biology
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• 제57권1호
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• pp.45-60
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• 2024

Morphologic changes in the brain through aging, as a physiologic process, may involve a wide range of variables including ventricular dilation, and sulcus widening. This study reports normal ranges of these changes as standard criteria. Normal brain computed tomography scans of 400 patients (200 males, 200 females) in every decade of life (20 groups each containing 20 participants) were investigated for subcortical/cortical atrophy (bicaudate width [BCW], third ventricle width [ThVW], maximum length of lateral ventricle at cella media [MLCM], bicaudate index [BCI], third ventricle index [ThVI], and cella media index 3 [CMI3], interhemispheric sulcus width [IHSW], right hemisphere sulci diameter [RHSD], and left hemisphere sulci diameter [LHSD]), ventricular symmetry. Distribution and correlation of all the variables were demonstrated with age and a multiple linear regression model was reported for age prediction. Among the various parameters of subcortical atrophy, BCW, ThVW, MLCM, and the corresponding indices of BCI, ThVI, and CMI3 demonstrated a significant correlation with age (R²≥0.62). All the cortical atrophy parameters including IHSW, RHSD, and LHSD demonstrated a significant correlation with age (R²≥0.63). This study is a thorough investigation of variables in a normal brain which can be affected by aging disclosing normal ranges of variables including major ventricular variables, derived ventricular indices, lateral ventricles asymmetry, cortical atrophy, in every decade of life introducing BW, ThVW, MLCM, BCI, ThVI, CMI3 as most significant ventricular parameters, and IHSW, RHSD, LHSD as significant cortical parameters associated with age.

• 대한간호학회지
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• 제44권1호
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• pp.75-85
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• 2014

Purpose: The aim of this study was to explore how individual factors, physiologic factors, symptoms, environmental factors, functional status and health perception predict the quality of life (QOL) for older adults with osteoarthritis and to provide guidelines for interventions and strategies to improve QOL in these patients. The conceptual model was based on the Wilson and Cleary's Model. Methods: Data were analyzed using SPSS WIN 20.0 and AMOS 19.0 program. Results: The proposed model was a good fit for the data based on the model fit indices. Based on the constructed model, individual factors, social support, functional status and health perception were founded to have direct effects on QOL. Symptom had a indirect effect on QOL. Social support had a significant effect on QOL, and this model explained 63.6% of the variance in QOL. Conclusion: The results of this study suggest that nursing strategies to increase QOL in this population should contain social support to promote QOL and manage functional limitations and health perception.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제2권2호
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• pp.139-146
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• 1999

목 적: 소아에서 흔히 볼 수 있는 반복적 구토 또는 게우기는 대부분 생리적 위식도 역류에 기인하지만 치료가 필요한 병적인 역류와 감별이 필요하다. 병적 역류의 진단에 이용되는 24시간 식도산도 측정의 임상적 의의와 더불어 역류지표들을 평가해 보고자 본 연구를 시행하였다. 대상 및 방법: 반복적 구토 또는 게우기를 주소로 내원한 환아들 중 glass electrode 및 GastrograpH (MIC, Switzerland)를 이용하여 24시간 식도 산도측정을 시행한 87례를 대상으로 병적 역류의 연령별 빈도를 알아보고, 생리적 및 병적 역류군의 역류 지표들의 평가와 더불어 두 군내에서의 하루중 시간대 별 역류 지수의 차이를 알아보고자 하였다. 결 과: 총 87명 중 병적 역류 환아는 32명(36.8%) 였으며, 연령별로는 6개월 미만에서 32.5%, 6개월~1세 사이 13.3%, 1~2세 사이 61.5%, 2~3세 사이 14.3%, 3세 이상에서는 66.7%에서 병적역류를 보였다. 생리적 역류군에서 총 역류지수는 1세미만에서 $3.7{\pm}2.9%$, 1세 이상에서 $1.8{\pm}1.5%$로 1세 전후에서 유의한 차이(p=0.02)를 보였으며, 하루 시간대별 1세 전후의 역류지수는 아침시간대에서만 1세 이하군이 의의 있게(p=0.04) 높았다. 역류횟수는 각각 $118{\pm}150$, $108{\pm}104$회로 1세 전후에서 유의한 차이는 없었다. 5분 이상 지속된 역류횟수는 1세 전후에서 각각 $1.7{\pm}1.9$, $0.8{\pm}1.0$회로 1세이하에서 유의하게(p=0.03) 많았으며, 가장 긴 1회 역류시간은 1세 전후에서 각각 $604{\pm}551$초, $275{\pm}296$초로 1세 이하에서 유의하게(p=0.007) 길었다. 병적 역류군에서 총역류지수는 1세 미만에서 $17.7{\pm}11.6%$, 1세 이상에서$7.7{\pm}2.9%$였고 역류횟수는 1세 전후에서 각각 $365{\pm}224$, $294{\pm}202$회였으며, 5분 이상 지속된 역류횟수는 $8.9{\pm}4.6$, $3.2{\pm}1.8$회였다. 가장 긴 1회 역류시간은 1세 전후에서 각각 $1955{\pm}2190$초, $1093{\pm}706$초였다. 생리적 및 병적 역류군 각각에서 하루 시간대 사이의 역류 지수를 비교한 결과 유의한 차이는 없었다. 결 론: 반복적 구토 또는 게우기를 주소로 내원한 환아에서 glass electrode 및 GastrograpH를 이용한 24시간 식도 산도 측정 검사상 1세 미만에서는 역류 지수 10%, 1세 이상에서는 5%를 기준으로 했을 때 병적 역류는 36.8%에서 관찰되었다. 생리적 및 병적 역류군의 시간대별 역류 지수 사이에는 유의한 차이가 없었다. 본 연구에서 병적 역류군의 역류발생빈도가 연령에 따라 차이가 크며, 특히 1~2세 사이의 환아에서 그 비율이 현저히 높았고, 또한 1세 전후의 역류지수도 현저한 차이를 보이므로, 향후 보다 많은 영유아들을 대상으로 조사 분석하여 1~2세 사이의 병적 역류의 기준 역류 지수를 5~10% 사이에서 더 세분하는 것이 필요할 것으로 생각된다.

• Journal of Korean Biological Nursing Science
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• 제14권1호
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• pp.57-65
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• 2012

Purpose: The purposes of this study were to identify the effect of music therapy on the physiologic index, anxiety and dyspnea of patients who are weaning from mechanical ventilators, and to compare the effects between western and Korean traditional music. Methods: The research format is repeated measures design. The subject group consisted of 21 patients being weaned from mechanical ventilators in a tertiary general hospital in Seoul. Each patient randomly received western music, rest, and Korean traditional music. Western and Korean traditional music were played on an MP3 head phone for 30 minutes. Patients get 30 minutes of rest between the 2 music styles and the rest period. Physiological indices, anxiety and dyspnea were measured before and after patients listened to both styles of music and the rest period. Anxiety and dyspnea were measured with a visual analogue scale. Results: Respiratory rates (RR), rapid shallow breath indexes (RSBI), anxiety and dyspnea decreased, and tidal volume (TV) increased after listening to Western and Korean tradition music in patients weaning from mechanical ventilators. Compared to western music, Korean traditional music yielded significant decreases in RR, RSBI, anxiety and dyspnea, and an increase of TV. Conclusion: Western and Korean traditional music would decrease RR, RSBI, anxiety and dyspnea and increase TV of patients who are weaning from mechanical ventilators. The effects are more pronounced in patients listening to Korean traditional music compared to western music.

• International Journal of Vascular Biomedical Engineering
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• 제1권1호
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• pp.13-23
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• 2003

Backgrounds: The present study in angulated coronary stenosis was to evaluate the influence of velocity and wall shear stress (WSS) on coronary atherosclerosis, the changes of hemodynamic indices following coronary stenting, as well as their effect of evolving in-stent restenosis using human in vivo hemodynamic parameters and computed simulation quantitatively and qualitatively. Methods: Initial and follow-up coronary angiographies in the patients with angulated coronary stenosis were performed (n=80). Optimal coronary stenting in angulated coronary stenosis had two models: < 50 % angle changed(model 1, n=43), > 50% angle changed group (model 2, n=37) according to percent change of vascular angle between pre- and post-intracoronary stenting. Flow-velocity wave obtained from in vivo intracoronary Doppler study data was used for in vitro numerical simulation. Spatial and temporal patterns of velocity vector and recirculation area were drawn throughout the selected segment of coronary models. WSS of pre/post-intracoronary stenting were calculated from three-dimensional computer simulation. Results: Follow-up coronary angiogram demonstrated significant difference in the percent of diameter stenosis between two groups (group 1: $40.3{\pm}30.2$ vs. group 2: $25.5{\pm}22.5%$, p<0.05). Negative WSS area on 3D simulation, which is consistent with re-circulation area of velocity vector, was noted on the inner wall of post-stenotic area before stenting. The negative WSS was disappeared after stenting. High spatial and temporal WSS before stenting fell into within physiologic WSS after stenting. This finding was prominent in Model 2 (p<0.01) Conclusions: The present study suggests that hemodynamic forces exerted by pulsatile coronary circulation termed as WSS might affect on the evolution of atherosclerosis within the angulated vascular curvature. Moreover, geometric change, such as angular difference between pre / post-intracoronary stenting might give proper information of optimal hemodynamic charateristics for vascular repair after stenting.

• 대한핵의학회지
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• 제10권1호
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• pp.21-34
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• 1976

The diagnosis of iron deficiency rests upon the correct evaluation of body iron stores. Morphological interpretation of blood film and the red cell indices are not reliable and often absent in mild iron deficiency. Serum iron levels and iron-binding capacity are more sensitive indices of iron deficiency, but they are often normal in iron depletion and mild iron deficiency anemia. They are also subject to many variables which may introduce substantial errors and influenced by many pathologic and physiologic states. Examination of the bone marrow aspirate for stainable iron has been regarded as one of the most sensitive and reliable diagnostic method for detecting iron deficiency, but this also has limitations. Thus, there is still need for a more practical, but sensitive and reliable substitute as a screening test of iron deficiency. Pollack et al. (1965) observed that the intestinal absorption of cobalt was raised in iron-deficient rats and Valberg et al. (1969) found that cobalt absorption was elevated in patients with iron deficiency. A direct correlation was demonstrated between the amounts of radioiron and radiocobalt absorbed. Unlike iron, excess cobalt was excreted by the kidney, the percentage of radioactivity in the urine being directly related to the percentage absorbed from the gastrointestinal tract. Recently a test based on the urinary excretion of an oral dose of $^{57}Co$ has been proposed as a method for detecting iron deficiency. To assess the diagnostic value of urinary cobalt excretion test cobaltous chloride labelled with $1{\mu}Ci\;of\;^{58}Co$ was given by mouth and the percentage of the test dose excreted in the urine was measured by a gamma counter. The mean 24 hour urinary cobalt excretion in control subjects with normal iron stores was 6.1% ($1.9{\sim}15.2%$). Cobalt excretion was markedly increased in patients with iron deficiency and excreted more than 29% of the dose. In contrast, patients with anemia due to causes other than iron deficiency excreted less than 27%. Hence, 24 hour urinary cobalt excretion of 27% or less in a patient with anemia suggets that the primary cause of the anemia is not iron deficiency. A value greater than 27% in an anemic subject suggests that the anemia is caused by iron deficiency. The cobalt excretion test is a simple, sensitive and accurate method for the assessment of body iron stores. It may be particularly valuable in the epidemiological studies of iron deficiency and repeated evaluations of the body iron stores.