• 환경생물
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• 제29권4호
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• pp.373-378
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• 2011

Our aim was to investigate the genotoxicity of ambient air in the Krak$\acute{o}$w area after Fukushima Nuclear Power Plant (NPP) accident and compare with results from Chernobyl fallout. For the detection of ambient air genotoxicity the technique for screening gene mutation frequency in somatic cells of the $Tradescantia$ stamen hairs ($Trad$-SH assay) was used. Since 11th of March 2011 (Fukushima NPP accident), several pots containing at least 15 shoots of bioindicating plants were exposed to ambient air at 2 sites in the Krak$\acute{o}$w surrounding area, one in the city center, and about 100 pots in a control site (in the glasshouse of the Institute of Nuclear Physics) Continuous screening of mutations was performed. Progenies of 371,090 cells exposed were analyzed. Mutation frequency obtained in the first 10 days has shown a mean control level (GMF*100=$0.06{\pm}0.01$). At scoring period related to influence of a potential Fukushima fallout, a significant increase of gene mutation frequencies above the control level was observed at each site in the range, 0.10~0.33 depending on the location, (mean value for all sites GMF*100=$0.19{\pm}0.05$) that was associated with a strong expression of toxic effects. In the reported studies following the Chernobyl NPP accident monitoring $in$ $situ$ of the ambient air genotoxicity was performed in the period since April $29^{th}$ till June $3^{rd}$ 1986 also with Trad-SH bioindicator. In general, mutation frequency increases due to Chernobyl fallout(GMF*100=$0.43{\pm}0.02$) were corresponding to fluctuation of radioactivity in the air reported from physical measures, and to published reports about increase in chromosome aberration levels. Although, recent data obtained from monitoring of the ambient air quality in the Krak$\acute{o}$w and surroundings are lower when compared to results reported after Chernobyl NPP accident, though results express a significant increase above the control level and also are corresponding with increased air radioactivity reported from physical measurements. Statistically significant in comparison to control increase in gene mutation rates and more prolonged than that after Chernobyl fallout increase of GMF was observed during the period following the Fukushima NPP failure.

• 한국의학물리학회지:의학물리
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• 제28권4호
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• pp.156-163
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• 2017

To verify the usefulness of a steam sterilizer equipped with an electronic Bowie-Dick test system, this study was carried out using two methods, utilizing both a steam sterilizer and an electronic Bowie-Dick tester. The first method is to confirm the error detection of the chemical Bowie-Dick test pack and the electronic Bowie-Dick tester in a malfunctioning sterilizer environment. For this purpose, the Bowie-Dick test program for the steam sterilizer was used to test three types of test packs commonly used in hospitals and the electronic Bowie-Dick tester by changing the set values of temperature, time, and vacuum frequency. The second is an experiment to check the sterilizer's normal operation with the electronic Bowie-Dick tester and the usefulness of grasping the cause of the malfunction. The results showed that the sterilization temperature was the same as that of the test pack at a temperature $1{\sim}6^{\circ}C$ lower than the reference temperature of $134^{\circ}C$. In the test with the sterilization exposure time as a variable, there was a normal discoloration at a time difference of 30~90 s. In the experiment using the number of vacuum cycles, the test was correct by performing the normal discoloration only at the normal condition of 3 times. The test results of 30 hospitals were 100 failure tests by a total of 291 Bowie-Dick tests. Of these, the failure factors related to an internal temperature that the chemical test packs could not detect were the greatest, and the four factors related to temperature, including the internal temperature, were found to be 71.18% of total malfunctions. In addition, the Bowie-Dick tester was provided within 30 min after the start of the Bowie-Dick test to confirm the performance of the sterilizer and the detailed cause. A steam sterilizer equipped with an electronic Bowie-Dick test system is used to manage individual sterilizers. In the current steam sterilizer with many temperature-related errors, it is possible to check the malfunction of the temperature difference that the test pack cannot detect, and the cause of error for the sterilizer is immediately detected after the test. The steam sterilizer equipped with the electronic Bowie-Dick test system assists with infection control with accurate sterilizer performance assurance.

• Earthquakes and Structures
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• 제8권3호
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• pp.485-509
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• 2015

This paper presents the experimental results obtained by applying frequency-domain structural health monitoring techniques to assess the damage suffered on a special type of damper called Web Plastifying Damper (WPD). The WPD is a hysteretic type energy dissipator recently developed for the passive control of structures subjected to earthquakes. It consists of several I-section steel segments connected in parallel. The energy is dissipated through plastic deformations of the web of the I-sections, which constitute the dissipative parts of the damper. WPDs were subjected to successive histories of dynamically-imposed cyclic deformations of increasing magnitude with the shaking table of the University of Granada. To assess the damage to the web of the I-section steel segments after each history of loading, a new damage index called Area Index of Damage (AID) was obtained from simple vibration tests. The vibration signals were acquired by means of piezoelectric sensors attached on the I-sections, and non-parametric statistical methods were applied to calculate AID in terms of changes in frequency response functions. The damage index AID was correlated with another energy-based damage index -ID- which past research has proven to accurately characterize the level of mechanical damage. The ID is rooted in the decomposition of the load-displacement curve experienced by the damper into the so-called skeleton and Bauschinger parts. ID predicts the level of damage and the proximity to failure of the damper accurately, but it requires costly instrumentation. The experiments reported in this paper demonstrate a good correlation between AID and ID in a realistic seismic loading scenario consisting of dynamically applied arbitrary cyclic loads. Based on this correlation, it is possible to estimate ID indirectly from the AID, which calls for much simpler and less expensive instrumentation.

• Healthcare Informatics Research
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• 제24권4호
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• pp.346-358
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• 2018

Objectives: The association between obstructive sleep apnea (OSA) and mortality or serious cardiovascular events over a long period of time is not clearly understood. The aim of this observational study was to estimate the clinical effectiveness of continuous positive airway pressure (CPAP) treatment on an outcome variable combining mortality, acute myocardial infarction (AMI), and cerebrovascular insult (CVI) during a follow-up period of 15.5 years ($186{\pm}58$ months). Methods: The data set consisted of 978 patients with an apnea-hypopnea index (AHI) ${\geq}5.0$. One-third had used CPAP treatment. For the first time, a data-driven causal Bayesian network (DDBN) and a hypothesis-driven causal Bayesian network (HDBN) were used to investigate the effectiveness of CPAP. Results: In the DDBN, coronary heart disease (CHD), congestive heart failure (CHF), and diuretic use were directly associated with the outcome variable. Sleep apnea parameters and CPAP treatment had no direct association with the outcome variable. In the HDBN, CPAP treatment showed an average improvement of 5.3 percentage points in the outcome. The greatest improvement was seen in patients aged ${\leq}55$ years. The effect of CPAP treatment was weaker in older patients (>55 years) and in patients with CHD. In CHF patients, CPAP treatment was associated with an increased risk of mortality, AMI, or CVI. Conclusions: The effectiveness of CPAP is modest in younger patients. Long-term effectiveness is limited in older patients and in patients with heart disease (CHD or CHF).

• 한국표면공학회지
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• 제29권6호
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• pp.683-690
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• 1996

In this study, the diffusion barrier properties of $1000 \AA$ thick molybdenum compounds (Mo, Mo-N, $MoSi_2$, Mo-Si-N) were investigated using sheet resistance measurements, X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Scanning electron microscopy (SEM), and Rutherford backscattering spectrometry (RBS). Each barrier material was deposited by the dc magnetron sputtering, and annealed at 300-$800^{\circ}C$ for 30min in vacuum. Mo and $MoSi_2$ barrier were failed at low temperature due to Cu diffusion through grain bound-aries and defects of Mo thin film and the reaction of Cu with Si within $MoSi_2$ respectively. A failure temperature could be raised to $650^{\circ}C$-30min in the Mo barrier system and to $700^{\circ}C$-30min in the Mo-silicide system by replacing Mo and $MoSi_2$ with Mo-N and Mo-Si-N, respectively. The crystallization temperature in the Mo-silicide film was raised by the addition of $N_2$. It is considered that not only the N, stuffing effect but also the variation of crystallization temperature affects the reaction of Cu with Si within Mo-silicide. It was found that Mo-Si-N is more effective barrier than Mo, $MoSi_2$, or Mo-N to copper penetration preventing Cu reaction with the substrate for 30min at a temperature higher than $650^{\circ}C$.

• 한국진공학회지
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• 제16권5호
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• pp.348-352
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• 2007

반도체 기술이 초고집적화 되어감에 따라 미세화공정에 의하여 소자의 크기가 급격히 줄어들고 있으며, 공정에서는 선폭이 크게 줄어드는 추세이다. 또한 박막을 다층으로 제조하여 소자의 집적도를 높이는 것이 중요한 이슈가 되고 있다. 이와 같은 수많은 제조 공정을 거치는 동안, Si 기판과 금속 박막사이에는 확산에 의한 많은 문제점들이 발생되고 있기 때문에, 이러한 금속과 Si 사이의 확산을 방지하는 것이 큰 이슈로 부각되어 왔다. 특히 Cu는 낮은 온도에서도 Si과 확산을 일으켜 Si 기판과 접합에서 확산에 의한 소자 failure 등이 문제로 발생하게 되며, 또한 선폭이 줄어듦에 따라 고열이 발생하여 실리콘으로 spiking이 발생하게 된다. 이를 방지하기 위하여 본 논문에서는 질소와 탄소를 첨가한 3개의 화합물로 구성된 Tungsten-Carbon-Nitrogen (W-C-N) 확산방지막을 사용하였다. 실험은 물리적 기상 증착법(PVD)으로 질소비율을 변화하며 확산방지막을 증착하였고, 이를 여러 가지 온도에서 열처리하여 열적인 안정성에 대한 실험을 실시하였다. 결정구조를 확인하기 위하여 X-ray Diffraction 분석을 통하여 확산방지막의 특성을 연구하였다.

• 항공우주시스템공학회지
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• 제13권6호
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• pp.17-25
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• 2019

항공기 엔진의 고장예지 및 건전성 관리(PHM)는 고장 또는 수명한계 도달 전에 잔존 유효 수명을 예측하는 것이다. PHM 기술 중 예측모델을 확립하는 방법은 물리 기반과 데이터 기반 방법이 있다. 물리기반 방법은 적은 데이터로 정확한 예측이 가능하지만 확립된 손상 물리 모델이 적어서 적용에 한계가 있다. 본 연구는 따라서 데이터 기반 방법을 적용하였으며, 수명 예측을 위해서 신경회로망 알고리즘 중 Multi-layer Perceptron을 이용하였다. 이를 위해 미국 항공우주국(NASA)에서 개발한 C-MAPSS 코드로 생성된 가상 데이터 세트를 이용하여 신경회로망을 학습하였다. 학습된 신경회로망 모델은 테스트 세트에 적용한 후 잔존 유효 수명의 신뢰구간을 예측하고 실제 값을 통해 정확도를 검증하였다. 또한 본 연구에서 제시된 방법을 기존 문헌의 것과도 비교하였고 그 결과 비교적 양호한 정확도를 확인할 수 있었다.

• 한국의학물리학회지:의학물리
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• 제14권1호
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• pp.20-27
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• 2003

컴퓨터에 의해 작동되는 선형가속기의 경우 모든 기기가 적절히 작동되는가를 확인하는 정도관리가 오작동으로 인한 환자 피해를 방지하기 위해 절대적으로 필요하다. 따라서 컴퓨터로직 및 마이크로 프로세서에 의해 작동되는 시스템의 안전을 고려하는 많은 보고서들이 발표되었다. 그 보고서에는 소프트웨어 및 하드웨어 고장으로 인해 발생하는 문제점들을 개선하기 위한 방법들이 제시하고 있다. 이와 관련하여 국내의 경우도 컴퓨터에 의해 작동되는 선형가속기의 수가 점차 적으로 증가하고 있는데 비해 체계적이고 일원화된 정도관리서가 없는 실정이다. 따라서 본 논문에서는 국내의 실정에 맞는 선형가속기 정도관리 기술을 개발하기 위한 기반으로 사용하기 위해 미국, 일본, 및 유럽에서 가장 일반적으로 사용되고 있는 정도관리서를 수집 및 요약하였다. 또한 각 나라간의 공통점 및 차이점이 비교분석 하였다. 국가별 정도관리를 비교한 결과 유럽의 경우 미국의 AAPM TG40을 참고자료로 주로 사용하였으며 중요한 정도관리의 항목은 점검주기에는 약간의 차이가 있으나 점검항목들은 거의 동일하다.

• Smart Structures and Systems
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• 제14권2호
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• pp.145-158
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• 2014

The objective of this study is to improve the survivability and reliability of the FBG sensor network in the structural health monitoring (SHM) system. Therefore, a model reconstruction soft computing recognition algorithm based on support vector regression (SVR) is proposed to achieve the high reliability of the FBG sensor network, and the grid search algorithm is used to optimize the parameters of SVR model. Furthermore, in order to demonstrate the effectiveness of the proposed model reconstruction algorithm, a SHM system based on an eight-point fiber Bragg grating (FBG) sensor network is designed to monitor the foreign-object low velocity impact of a CFRP composite plate. Simultaneously, some sensors data are neglected to simulate different kinds of FBG sensor network failure modes, the predicting results are compared with non-reconstruction for the same failure mode. The comparative results indicate that the performance of the model reconstruction recognition algorithm based on SVR has more excellence than that of non-reconstruction, and the model reconstruction algorithm almost keeps the consistent predicting accuracy when no sensor, one sensor and two sensors are invalid in the FBG sensor network, thus the reliability is improved when there are FBG sensors are invalid in the structural health monitoring system.

• Geomechanics and Engineering
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• 제11권1호
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• pp.1-39
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• 2016

The finite element method (FEM), discrete element method (DEM), and Discontinuous deformation analysis (DDA) are among the standard numerical techniques applied in computational geo-mechanics. However, in some cases there no possibility for modelling by traditional finite analytical techniques or other mesh-based techniques. The solution presented in the current study as a completely Lagrangian and mesh-free technique is smoothed particle hydrodynamics (SPH). This method was basically applied for simulation of fluid flow by dividing the fluid into several particles. However, several researchers attempted to simulate soil-water interaction, landslides, and failure of soil by SPH method. In fact, this method is able to deal with behavior and interaction of different states of materials (liquid and solid) and multiphase soil models and their large deformations. Soil indicates different behaviors when interacting with water, structure, instrumentations, or different layers. Thus, study into these interactions using the mesh based grids has been facilitated by mesh-less SPH technique in this work. It has been revealed that the fast development, computational sophistication, and emerge of mesh-less particle modeling techniques offer solutions for problems which are not modeled by the traditional mesh-based techniques. Also it has been found that the smoothed particle hydrodynamic provides advanced techniques for simulation of soil materials as compared to the current traditional numerical methods. Besides, findings indicate that the advantages of applying this method are its high power, simplicity of concept, relative simplicity in combination of modern physics, and particularly its potential in study of large deformations and failures.