• ETRI Journal
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• v.37 no.2
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• pp.204-211
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• 2015

For this study, we designed an implantable rectangular spiral antenna for medical biotelemetry in the Medical Implant Communications Service band (402 MHz to 405 MHz). The designed antenna has a U-shaped loop for impedance matching. The antenna impedance is easily adjusted by controlling the shape and length of the U-shaped loop. Significant design parameters were studied to understand their effects on the antenna performance. To verify the potential of the antenna for the desired applications, we fabricated a prototype and measured its performance in terms of the resonant characteristics and gain radiation patterns of the antenna. In the testing phase, the prototype antenna was embedded in human skin tissue-emulating gel, which was developed to simulate a real operation environment. The measured resonant characteristics show good agreement with the simulations, and the -10 dB frequency band is within the range of 398 MHz to 420 MHz. The antenna exhibits a maximum gain of -22.26 dBi and an antenna efficiency of 0.215%.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.2
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• pp.563-567
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• 2012

In our era there has been several anti-cancer drugs which have undergone both experimental and clinical trials; however, due to their poor solubilities, numerous side effects, insufficient bioavailability and poor compliance, many have resulted into poor outcomes. Therefore, our aim was to investigate the effects of novel hydrophilic taxanes analogues CQMU-0517 and CQMU-0519 on growth of A549 lung, SKVO3 ovary and MCF7 breast carcinoma cell lines. Different concentrations of original paclitaxel, CQMU-0517, original docetaxel and CQMU-0519 were utilized on three cell lines, where cell growth was assessed using cell culture kit-8 and flow cytometry analysis. The results unveiled that CQMU-0517 and CQMU-0519 suppressed cell growth in the three particular cell lines, cell cycle arrest being evident in the G2/M phase. Hence, the results showed that these new taxane analogues have potential and warrant future clinical trials.

• Steel and Composite Structures
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• v.36 no.6
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• pp.671-687
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• 2020

The aim of this research is to analyze buckling and bending behavior of a sandwich Reddy beam with porous core and composite face sheets reinforced by boron nitride nanotubes (BNNTs) and shape memory alloy (SMA) wires resting on Vlasov's foundation. To this end, first, displacement field's equations are written based on the higher-order shear deformation theory (HSDT). And also, to model the SMA wire properties, constitutive equation of Brinson is used. Then, by utilizing the principle of minimum potential energy, the governing equations are derived and also, Navier's analytical solution is applied to solve the governing equations of the sandwich beam. The effect of some important parameters such as SMA temperature, the volume fraction of SMA, the coefficient of porosity, different patterns of BNNTs and porous distributions on the behavior of buckling and bending of the sandwich beam are investigated. The obtained results show that when SMA wires are in martensite phase, the maximum deflection of the sandwich beam decreases and the critical buckling load increases significantly. Furthermore, the porosity coefficient plays an important role in the maximum deflection and the critical buckling load. It is concluded that increasing porosity coefficient, regardless of porous distribution, leads to an increase in the critical buckling load and a decrease in the maximum deflection of the sandwich beam.

• Journal of Contemporary Eastern Asia
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• v.13 no.1
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• pp.19-37
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• 2014

In an attempt to develop comprehensive evidence-based methods for evaluation of the R&D performance of cross-disciplinary projects, a joint bibliometric analysis of patents and publications was performed for two industry-university-government collaborative projects aimed at commercialization: Hokkaido University Research & Business Park Project (2003-2007; 63 inventors; 176 patents; 853 papers), and Matching Program for Innovations in Future Drug Discovery and Medical Care - phase I (2006-2010; 46 inventors; 235 patents; 733 papers). Besides the simple output indicators (for five years period), and citations (from the publication date to the end of 2012), science maps based on the network analysis of words and co-authorship relations were generated to identify the prominent research themes and teams. Our joint analysis of publications and patents yields objective and mutually complementing information, which provides better insights on research and commercialization performance of the large-scale projects. Hence, such analysis has potential for use in the industry-university project's performance evaluation.

• Advances in aircraft and spacecraft science
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• v.4 no.1
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• pp.21-35
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• 2017

Hydrogen peroxide is being considered as a monopropellant in micropropulsion systems for the next generation of miniaturized satellites ('nanosats') due to its high energy density, modest specific impulse and green characteristics. Efforts at the University of Vermont have focused on the development of a MEMS-based microthruster that uses a novel slug flow monopropellant injection scheme to generate thrust and impulse-bits commensurate with the intended micropropulsion application. The present study is a computational effort to investigate the initial decomposition of the monopropellant as it enters the catalytic chamber, and to compare the impact of the monopropellant injection scheme on decomposition performance. Two-dimensional numerical studies of the monopropellant in microchannel geometries have been developed and used to characterize the performance of the monopropellant before vaporization occurs. The results of these studies show that monopropellant in the lamellar flow regime, which lacks a non-diffusive mixing mechanism, does not decompose at a rate that is suitable for the microthruster dimensions. In contrast, monopropellant in the slug flow regime decomposes 57% faster than lamellar flow for a given length, indicating that the monopropellant injection scheme has potential benefits for the performance of the microthruster.

• Architectural research
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• v.18 no.4
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• pp.151-155
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• 2016

It is necessary to improve the performance of buildings with respect to the energy efficiency while improving the quality of occupants' lives through a sustainable built environment. During the design and development process, building projects must have a comprehensive, integrated perspective that seeks to reduce heating, cooling and lighting loads through climate-responsive designs. The aim of this study is to find an optimal thermal transmittance (U-values) for building envelope elements for low energy multi-rise residential buildings in the early design phase in Korea. The study found that using small U-values of $0.15w/m^2K$ for exterior walls, ceilings and floors and $1.0w/m^2K$ for south and north facing windows has resulted in energy reduction of 22.1%-59.4% in the south facing rooms and 43%-77.6% of the north facing rooms. It has also found the energy load reduction potential of using small U-values are higher on the north facing rooms. The findings of this study can be suggested to be used as a baseline case for low energy consumption studies. It can also be used to determine appropriate envelope materials and insulation values.

• Advances in nano research
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• v.6 no.2
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• pp.183-200
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• 2018

In the present study silver nanoparticles (AgNPs) were successfully synthesized using aqueous extract of Sargassum muticum. The aqueous extract (10%) treated with 1 mM silver nitrate solution resulted in the formation of AgNPs and the surface plasmon resonance (SPR) of the formed AgNPs was recorded at 360 nm using UV-Visible spectrophotometer. The molecules involved in the formation of AgNPs were identified by Fourier transform infrared spectroscopy (FT-IR), surface morphology was studied by using scanning electron microscopy (SEM), SEM micrograph clearly revealed the size of the AgNPs was in the range of 40-65 nm with spherical, hexagonal in shape and poly-dispersed nature, and X-ray diffraction spectroscopy (XRD) was used to determine the crystalline structure. High positive Zeta potential (36.5 mV) of formed AgNPs indicates the stability and XRD pattern revealed the crystal structure of the AgNPs by showing the Bragg's peaks corresponding to (111), (200), (311) and (222) planes of face-centered cubic crystal phase of silver. The synthesized AgNPs exhibited effective anticancerous activity (at doses 25 and $50{\mu}g/ml$ of AgNPs) against Breast cancer cell line (MCF7).

• Fisheries and Aquatic Sciences
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• v.18 no.3
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• pp.301-309
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• 2015

Chub mackerel, Scomber japonicus, larvae and juveniles were reared from hatching to 35 days after hatching (DAH), and the development of their digestive systems was histologically investigated. The larvae were initially fed on rotifers and Artemia nauplii starting around 19 DAH, and thereafter on Artemia nauplii, fish eggs, and a formulated feed mixture. The primitive digestive system differentiated at 3 DAH; the digestive tract was distinctively divided into the buccopharyngeal cavity, esophagus, stomach, air bladder, intestines, and rectum. The gastric gland and pyloric caeca first appeared at 5 and 7 DAH, respectively. The stomach was divided into cardiac, fundic, and pyloric regions in the preflexion phase. The number of gastric glands and pyloric caeca, as well as the volume of the gastric blind sac increased markedly, with development continuing into the juvenile stage. The precocious development of the digestive system during the larval period might be related to the early appearance of piscivory, which is able to support high growth potential. The organogenesis results obtained for this precocial species represent a useful tool to aid our understanding of the physiological requirements of larvae and juveniles to ensure optimal welfare and growth under aquaculture conditions, which will improve current rearing practices of this scombrid species.

• Journal of the Korean Society for Precision Engineering
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• v.32 no.10
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• pp.885-890
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• 2015

Walking on split-belt treadmill has been applied to study walking disabilities, such as osteoarthritis (OA), to show asymmetric walking characteristics. In this study, we compared asymmetric walking in OA patients with healthy subjects under split-belt conditions and examined the reproduction of walking asymmetry in OA. Seven OA patients were instructed to walk at four frequencies, while four healthy subjects walked on a treadmill with tied-belt and split-belt conditions. To compare walking asymmetries, kinetic and kinematic measurements were made using force-plates and motion capture cameras, and subsequently center of mass (CoM) velocity, mechanical work and potential energy were calculated. Horizontal velocity change during split-belt walking of healthy subjects was similar to OA patients. Difference of mechanical work during single support phase occurred due to fall of CoM in fast belt. OA walking asymmetry could be reproduced by reducing differences of belt speeds to prevent rapid fall of CoM.

• Journal of the Korean Ceramic Society
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• v.53 no.4
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• pp.406-410
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• 2016

Carbon-coated sodium iron pyrophosphate ($Na_2FeP_2O_7$) was prepared by a simple and low-cost pyro-synthesis route for further use as the cathode for Na-ion batteries. The X-ray diffraction (XRD) pattern of the sample annealed at $650^{\circ}C$ confirmed the pure triclinic phase of $Na_2FeP_2O_7$. Electron microscopy studies revealed a cross linked plate shape morphology of the $Na_2FeP_2O_7$ sample. When tested for application in Na-ion battery, the $Na_2FeP_2O_7$ cathode showed two redox pairs in the potential window of 2.0-4.0 V. The cathode registered initial discharge and charge capacities of 80.85 and 90 mAh/g, respectively, with good cycling performance.