• Journal of the Institute of Electronics Engineers of Korea TC
• /
• v.42 no.3 s.333
• /
• pp.39-44
• /
• 2005

The OFDM modulation and transmission block have been modeled in order to analyse the relationship between the 2.4GHz power amplifier distortion and output ACPR for the IEEE 802.11g wireless LAN. The nonlinear characteristic of the power amplifier has been modeled as AM-to-AM and AM-to-PM using the behavioral model, and the output spectrum is analysed with the phase distortion variation. Also, amplifier back-off value from P1dB to satisfy the required IEEE 802.11g standard spectrum mask s been simulated with modeled phase distortion, and the simulation data have been compared to the measured result by using the pre-distortion technique.

• Journal of the Institute of Convergence Signal Processing
• /
• v.9 no.3
• /
• pp.179-187
• /
• 2008

In this paper, we carried out the performance evaluation of depolarized fiber optic gyroscope(D-FOG) that was designed and fabricated with the low-cost optical communication single mode fiber and depolarizer. In order to reduce the phase error of D-FOG, the circuit of stabilized current and temperature of the light source was made and the performance was analyzed. The current and the temperature stability of the fabricated stabilization circuit were less than $200{\mu}A$ and $0.0098^{\circ}C$, respectively. Also, the D-FOG's experimental result showed that the value of the dynamic range of rotated rate, the scale factor error with a good linearity, and the zero bias drift were ${\pm}50^{\circ}/s$, 2.8881%, and $19.49^{\circ}/h$, respectively. The results indicated that a low-cost FOG was able to fabricate which was more cost effective than conventional FOG with a high-cost high-birefringent polarization maintaining fiber.

• The Transactions of the Korean Institute of Electrical Engineers P
• /
• v.63 no.2
• /
• pp.95-101
• /
• 2014

In this paper, UPS, with a built-in instantaneous sag drop compensation features, was developed to improve performance. The improved UPS, using instantaneous moving average method, compensates by quickly measuring the voltage and series inverter of half-bridge type, using line-interactive method that links with the voltage of the battery and power source, was developed. In addition, by developing a parallel inverter that uses a high-efficiency PWM switching method, overall UPS system was enhanced. To verify the performance of the proposed algorithm, single-phase 5[kVA] UPS systems were designed and the experimental system was constructed. The low-cost type of Cortex-M3 module CPU STM32F103R8T6 (32[bit]) is attached and the switching time of mode transfer was set within 4 [ms]. THD of the linear load operates in less than 3[%], and the stability of the output voltage operates in approximately ${\pm}2[%]$ range. The superior performance of the operations was confirmed with the system set as above.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.17 no.1 s.104
• /
• pp.45-51
• /
• 2006

In this paper, a new predistortion linearizer for controlling the amplitude of low frequency intermodulation distortion signals is proposed. The low frequency intermodulation distortion(IMD) components are generated by harmonic generator. A vector modulator, modulate fundamental signal with low frequency IMD signals, generates predistortion IMD signals and controls amplitude and phase of them with modulation factors. As a result, this predistorter is suppressed IMD signals of power amplifier effectively. The predistortion linearizer has been manufactured to operate in cellular base-station transmitting band($869{\sim}894\;MHz$). The experimental results show that IMD3 of power amplifier are improved more than 20 dB for CW two-tone signals. Also, it's improved the adjacent channel power ratio(ACPR) more than 10 dB for IS-95 CDMA IFA signals.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.23 no.6
• /
• pp.726-732
• /
• 2019

In this study, we proposed an asymmetric differential inductor to improve the linearity of differential power amplifiers. Considering the phase error between differential signals of the differential amplifier, the location of the center tap of the differential inductor was modified to minimize the error. As a result, the center tap was positioned asymmetrically inside the differential inductor. With the asymmetric differential inductor, the AM-to-AM and AM-to-PM distortions of the amplifier were suppressed. To confirm the feasibility of the inductor, we designed a 2.4 GHz differential CMOS PA for IEEE 802.11n WLAN applications with a 64-quadrature amplitude modulation (QAM), 9.6 dB peak-to-average power ratio (PAPR), and a bandwidth of 20 MHz. The designed power amplifier was fabricated using the 180-nm RF CMOS process. The measured maximum linear output power was 17 dBm, whereas EVM was 5%.

• Radiation Oncology Journal
• /
• v.23 no.1
• /
• pp.51-60
• /
• 2005

Purpose : Selective inhibition of multiple molecular targets may improve the antitumor activity of radiation. Two specific inhibitors of selective cyclooxygenase-2 (COX-2) and epidermal growth factor receptor (EGFR) were combined with radiation on the HeLa cell line. To investigate cooperative mechanism with selective COX-2 inhibitor and EGFR blocker, in vitro experiments were done. Materials and Methods : Antitumor effect was obtained by growth inhibition and apoptosis analysis by annexin V-Flous method. Radiation modulation effects were determined by the clonogenic cell survival assay. Surviving fractions at 2 Gy ($SF_2$) and dose enhancement ratio at a surviving fraction of 0.25 were evaluated. To investigate the mechanism of the modulation of radiosensitivity, the cell cycle analyses were done by flow cytometry. The bcl-2 and bax expressions were analyzed by western blot. Results : A cooperative effect were observed on the apoptosis of the HeLa ceil line when combination of the two drugs, AG 1478 and NS 398 with radiation at the lowest doses, apoptosis of $22.70\%$ compare with combination of the one drug with radiation, apoptosis of $8.49\%$. In cell cycle analysis, accumulation of cell on $G_0/G_l$ phase and decrement of S phase fraction was observed from 24 hours to 72 hours after treatment with radiation, AG 1478 and NS 398. The combination of NS 398 and AG 1478 enhanced radiosensitivity on a concentration-dependent manner in HeLa cells with dose enhancement ratios of 3.00 and $SF_2$ of 0.12 but the combination of one drug with radiation was not enhanced radlosensitivity with dose enhancement ratios of 1.12 and SF2 of 0.68 (p=0.005). The expression levels of bcl-2 and bax were reduced when combined with AG 1478 and NS 398. Conclusion : Our results indicate that the selective COX-2 inhibitor and EGFR blocker combined with radiation have potential additive or cooperative effects on radiation treatment and may act through various mechanisms including direct inhibition of tumor cell proliferation, suppression of tumor cell cycle progression and inhibition of anti-apoptotic proteins.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.33 no.4A
• /
• pp.440-449
• /
• 2008

In this paper, we propose a 16-QAM carrier recovery loop which is suitable for the implementation of Inmarsat M4 system receiver. Because the frequency offset of ${\pm}924\;Hz$ on signal bandwidth 33.6 kHz is recommended in Inmarsat M4 system specification, carrier recovery loop having stable operation in the channel environment with large relative frequency offset is required. the carrier recovery loop which adopts only PLL can't be stable in relatively large frequency offset environment. Therefore, we propose a carrier recovery loop which has stable operation in large relative frequency offset environment for Inmarsat M4 system. The proposed carrier recovery loop employed differential filter-based noncoherent UW detector which is robust to frequency offset, CP-AFC for initial frequency offset acquisition using UW signal, and 16-QAM DD-PLL for phase tracking using data signal to overcome large relative frequency offset and achieve stable carrier recovery performance. Simulation results show that the proposed carrier recovery loop has stable operation and satisfactory performance in large relative frequency offset environment for Inmarsat M4 system.

• Journal of Life Science
• /
• v.24 no.10
• /
• pp.1085-1091
• /
• 2014

The purpose of this study was to determine the effect of selenate on adipocyte differentiation and to identify genes involved in the modulation of adipogenesis in 3T3-L1 cells. To test the effect of selenate on adipocyte differentiation, adipogenesis was induced in cells using various concentrations ($0-100{\mu}M$) of selenate. Various phases of adipogenesis were induced: postconfluent (PC), early phase (EP, d0-d2), postmitotic growth arrest (PM, d2-d4), and all period (AP). The PC cells exposed to selenate for 24 h displayed dose-dependent inhibition of intracellular lipid droplet accumulation on day 6 of adipogenesis. Two days of selenate treatment at EP or AP inhibited adipogenesis, with an approximately 20-80% reduction in lipid accumulation compared to that of a control (p<0.05). When preadipocytes were exposed to selenate during the PM period, the antiadipogenic effect of selenate was attenuated. Two types of selenoprotein genes (Seps1 and Sepp1) were up-regulated by the selenate treatment during mitotic clonal expansion, whereas these genes were down-regulated during PM growth arrest (p<0.05). The findings demonstrate the antiadipogenic function of selenate and the possible involvement of Sepp1 and Seps1 genes in selenate-inhibited adipogenesis in 3T3-L1 cells.

• Journal of dental hygiene science
• /
• v.15 no.4
• /
• pp.424-429
• /
• 2015

The aim of this study was to investigate whether peripheral or central administration of triptolide is involved in pain modulation in inflammatory orofacial pain. The inflammatory orofacial pain was induced by the injection of 5% formalin into right vibrissa pad of rats. The pain behavioral response was measured the number of grooming or scratching on the orofacial area for 9 successive 5 minutes intervals. Triptolide was administrated into the identified vibrissa pad (12.5, 25, $50{\mu}g/50{\mu}l$) or intracisternal space (0.01, 0.1, $1{\mu}g/10{\mu}l$) 10 min before formalin injection. The nociceptive responses were reduced in the 2nd phase (11~45 minutes), particularly 20, 30 minutes after fomalin injection following administration of triptolide into vibrissa pad (25, $50{\mu}g/50{\mu}l$). Intracisternal ($1{\mu}g/10{\mu}l$) administration of triptolide alleviated the formalin-induced pain behaviors in the 2nd phase, especially 25~40 minutes after formalin injection. Triptolide could be a promising analgesic agent in the treatment of inflammatory orofacial pain.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.5
• /
• pp.2683-2688
• /
• 2016

A salt compound of a curcumin analogue, potassium pentagamavunon-0 (K PGV-0) has been synthesized to improve solubility of pentagamavunon-0 which has been proven to have anti-proliferative effects on several cancer cells. The purpose of this study was to investigate cytotoxic activity and metastasis inhibition by K PGV-0 alone and in combination with achemotherapeutic agent, doxorubicin (dox), in breast cancer cells. Based on MTT assay analysis, K PGV-0 showed cytotoxic activity in T47D and 4T1 cell lines with $IC_{50}$ values of $94.9{\mu}M$ and $49.0{\pm}0.2{\mu}M$, respectively. In general, K PGV-0+dox demonstrated synergistic effects and decreased cell viability up to 84.7% in T47D cells and 62.6% in 4T1 cells. Cell cycle modulation and apoptosis induction were examined by flow cytometry. K PGV-0 and K PGV-0+dox caused cell accumulation in G2/M phase and apoptosis induction. Regarding cancer metastasis, while K PGV-0 alone did not show any inhibition of 4T1 cell migration, K PGV-0+dox exerted inhibition. K PGV-0 and its combination with dox inhibited the activity of MMP-9 which has a pivotal role in extracellular matrix degradation. These results show that a combination of K PGV-0 and doxorubicin inhibits cancer cell growth through cell cycling, apoptosis induction, and inhibition of cell migration and MMP-9 activity. Therefore, K PGV-0 may have potential for development as a co-chemotherapeutic agent.