• 대한후두음성언어의학회지
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• 제4권1호
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• pp.24-32
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• 1991

Cleft palate or velopharyngeal incompetence shows many disorders and disabilities affecting speech transmission. including distortion. substitution. and the nasalization of the vowels. The nasalized vowels are produced primarily by lowering of the velum. resulting in opening a side passage for the air flow through the nasal cavity. These abnormal movements give rise to complex modification of the physical property of the sound or in the sound spectrum. The authors employed Sonagraph$^{\circledR}$ as a sound analyzer in order to ascertain the features which characterize the nasalization of vowels. Twenty healthy Korean male adult voluteers were analyzed in artificial conditions of anterior and posterior nasal obstruction. and velo-pharyngeal incompetence. The results were as follows : 1) Fundamental frequency was not changed by nasal obstruction or velopharyngeal incompetence. 2) There was no significant difference of the formant intensity between normal and nasal vowels. 3) In VPI, a decrease of the frequency of $F_2$ was observed in /e/ and /i/ vowels(p<0.001). 4) In VPI, the $F_2$ was frequently missed in /o/ and /u/ vowels. 5) In the consonant spectra of VPI, the 'release burst' was usually not observed.

• 한방재활의학과학회지
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• 제18권1호
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• pp.111-123
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• 2008

Objectives : The objective of this study was to investigate the outcomes of functional electrical stimulation (FES) which was applied twice a day in patients with dysphagia after stroke. Methods : Eleven patients with dysphagia after stroke were participated. The electrical stimulator with two channels was employed for forty minutes daily or forty minutes twice a day for fifteen days. Participants were divided into two groups by random method; The FES was performed twice a day for Twice-FES group (n=6), and once a day for Standard-FES group (n=5). For evaluation of dysphagia, the functional dysphagia scale by videofluoroscopic swallowing study, and swallow function scoring system by six clinical swallowing stage were assessed at pre- and post-treatment. Results : In both groups, there was a significant decrease of total functional dysphagia scales after FES treatment (p<0.05) and the results mainly affected the pharyngeal phase of deglutition. There was no significant difference between the two groups in total functional dysphagia scales, but the Twice-FES group had a decreased residue in oral cavity compared to the standard FES group. In both groups, there were significant improvements in swallow function scoring system (p<0.05). The twice-FES group had more high clinical swallowing stages. Conclusions : The results demonstrated that FES is a clinically effective intervention in treatment of stroke patients with dysphagia. Moreover, the treatment applied twice a day had relatively positive effects on the reduction of oral cavity residue and the improvement of clinical swallowing stage.

• Journal of Korean Neurosurgical Society
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• 제49권4호
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• pp.248-251
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• 2011

Objective : In the field of spinal surgery, a few laboratory results or clinical cases about robotic spinal surgery have been reported. In vivo trials and development of related surgical instruments for spinal surgery are required before its clinical application. We investigated the use of the da $Vinci^{(R)}$ Surgical System in spinal surgery at the craniovertebral junction in a human cadaver to demonstrate the efficacy and pitfalls of robotic surgery. Methods : Dissection of pharyngeal wall to the exposure of C1 and odontoid process was performed with full robotic procedure. Although assistance of another surgeon was necessary for drilling and removal of odontoid process due to the lack of appropriate end-effectors, successful robotic procedures for dural sutures and exposing spinal cord proved its safety and dexterity. Results : Robot-assisted odontoidectomy was successfully performed in a human cadaver using the da $Vinci^{(R)}$ Surgical System with few robotic arm collisions and minimal soft tissue damages. Da $Vinci^{(R)}$ Surgical System manifested more dexterous movement than human hands in the deep and narrow oral cavity. Furthermore, sutures with robotic procedure in the oral cavity demonstrated the advantage over conventional procedure. Conclusion : Presenting cadaveric study proved the probability of robot-assisted transoral approach. However, the development of robotic instruments specific to spinal surgery must first precede its clinical application.

• 대한치과교정학회지
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• 제53권3호
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• pp.175-184
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• 2023

Objective: To evaluate and compare a series of volume changes in the nasal cavity (NC), nasopharynx, oropharynx, and maxillary sinuses (MS) in growing Class III patients after either rapid palatal expansion (RPE) or alternate rapid maxillary expansion and constriction (Alt-RAMEC) followed by facemask (FM) therapy, by using cone-beam computed tomography (CBCT). Methods: Forty growing Class III patients were retrospectively selected and divided into two matched groups: RPE/FM (14 females, 6 males; mean age, 9.66 ± 1.23 years) and Alt-RAMEC/FM groups (14 females, 6 males; mean age, 10.28 ± 1.45 years). The anteroposterior and vertical displacements of Point A, the volumes of the NC, nasopharyngeal, oropharyngeal, and MS were measured at different time points: pretreatment (T1), postexpansion (T2), and postprotraction (T3). Results: Both groups demonstrated significant maxilla advancement (by 1.3 mm) during expansion, with a statistically significant intergroup difference during protraction (RPE/FM, 1.1 mm; Alt-RAMEC/FM, 2.4 mm; p < 0.05) and throughout the treatment (RPE/FM, 2.4 mm; Alt-RAMEC/FM, 3.7 mm; p < 0.05). NC and nasopharyngeal airway volumes increased significantly in both groups after expansion, protraction, and treatment. The oropharyngeal and MS volumes increased in both groups after protraction and post-treatment. However, no volumetric differences were observed between the two groups. Conclusions: There was no significant difference in airway volume changes, including NC, nasopharyngeal, oropharyngeal airway, and MS, between RPE/FM and Alt-RAMEC/FM groups at different time points. Although there was significantly more forward movement after protraction in the Alt-RAMEC/FM group, the difference was deemed too small to be clinically relevant.

• 한국지능시스템학회논문지
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• 제11권6호
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• pp.510-515
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• 2001

일반적으로 음성신호로부터 사람의 감정을 인식할 수 있는 요소는(1)대화의 내용에 사용한 단어, (2)톤 (tore), (3)음성신호의 피치(Pitch), (4)포만트 주파수(Formant Frequencey)그리고 (5)말의 빠르기(Speech Speed)(6)음질(Voice Quality)등이다. 사람의 경우는주파수 같은 분석요소 보다 톤과 단어 빠르기, 음질로 감정을 받아들이게 되는것이 자연스러운 방법이므로 당연히 후자의 요소들이 감정을 분류하는데 중요한 인자로쓰일 수있다. 그리고, 종래는 주로 후자의 효소들을 이용하였는데, 기계로써 구현하기 위해서는 포만트 주파수를 사용할 수있게 되는것이 도움이 된다. 그러므로, 본 연구는 음성 신호로부터 피치와 포만트, 그리고 말의 빠르기 등을 이용하여 감성인식시스템을 구현하는것을 목표로 연구를 진행하고 있으며, 그 1단계 연구로서 본 논문에서는 화가 나서 내뱉는 말을 기반으로 하여 화난 감정의 독특한 특성을 찾아내었다.

• 한국어병학회지
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• 제9권2호
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• pp.127-135
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• 1996

남해안 아귀, Lophiomus setigerus에서 기생성 요각류, Acanthochondria spirigera(Chondracanthidae, Poecilostomatoida)이 채집되었다. 이 종은 한국 미기록종이다. A. spirigera는 나선형으로 굽어지는 알주머니를 가짐으로서 Acanthochondria속 다른 종과 쉽게 구별된다. 또한 이 기생충은 5월을 제외하고 1~4월에 아귀 아가미에서 채집되었다. 감염률과 상대 감염밀도는 1월에서 5월로 진행됨에 따라 점차 감소하였다. Acanthochondria spirigera는 아귀 구강에 제한적으로 기생하며, 숙주의 아가미에서 분비되는 점액질 등을 섭취하면서 서식한다. 그리고 수컷은 암컷의 복절에 작은 혹처럼 부착되어 있다.

• Journal of Oral Medicine and Pain
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• 제26권2호
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• pp.121-126
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• 2001

Mucous membrane pemphigoid is uncommom disease in oral cavity and synonymous with cicatricial pemphigoid. This disease is caused by autoimmune reaction that autoantibody reacts antigen located in basement membrane and epithelium is separated from underlying connective tissue. It affects female over sixth decade, commonly. Oral mucosa, especially gingiva is common site but conjunctival, nasal, pharyngeal, laryngeal, esophageal, varginal mucosa and skin are involved. Intraoral findings show Nikolsky sign, irregular erythema, erosion, vesicle, and ulceration at mucous membrane. To differentiate from diseases of positive Nikolsky sign, should perform histologic, immunologic test. Histologic features show subbasilar cleft and direct immunologic features show IgG, C3 deposits at basement membrane in linear pattern. Mucous membrane pemphigoid is incurable disease because symptoms are repetitively improved or worsed for several years. Patiens are commonly managed with topical and systemic steroid. To avoid side effects of prolonged steroid therapy and to maintain immunosupressive effects, combination therapy of azathioprine with steroid is effective. This case reports that mucous membrane pemphigoid is diagnosed based on clinical and histologic features, is treated with topical, systemic steroid and azathioprine therapy.

• 대한후두음성언어의학회지
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• 제33권2호
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• pp.77-82
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• 2022

Hunminjeongeum was made by the Great King Sejong, and composed of 17 consonant and 11 vowel letters. All the 28 letters were made according to the shape of vocal organ or space at the point of articulation for each letters. This review article focused on phonetic and phoniatric consideration for explanation of the designs of the middle vowel letters, especially three main vowel letters [ • (天, heaven), ㅡ (地, earth), ㅣ (人, human)] using video-fluoroscopic evaluation as well as computed tomography scanning, etc. During articulating / • / sound, a ball-like space at frontal portion of the oral cavity was found, tongue was contracted, and sound was deep (舌縮而聲深). During /ㅡ/ sound, a flat air space between oral tongue and hard palate was created. Tongue was slightly contacted neither deep nor shallow (舌小縮而聲不深不淺). During /ㅣ/ sound, tongue was not contacted and Sound is light (舌不縮而聲淺). Tongue was moved forward making longitudinal oro-pharyngeal air space. So, I'd like to suggest that we had better change the explanation drawing from a philosophical modeling to a more scientific modeling from real vocal tract space modeling during articulating middle vowels of Hunminjeongeum.

• Archives of Plastic Surgery
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• 제38권2호
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• pp.199-202
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• 2011

Purpose: Hyoid bone is a U-shaped bone in the anterior of the neck. Hyoid bone fractures are exceedingly rare and represent only 0.002% of all fractures because of its protective position relative to the mandible and its suspension by elastic musculature. We report a patient who presented hyoid bone fracture associated with hypoglossal nerve palsy. We also discuss the possible complication and treatment. Methods: A 69-year-old man was transferred from another institution because of persistent purulent discharge from the left chin. He had a history of trauma in which a knuckle crane grabbed his face and neck in the construction site. A CT scan at the time of the accident demonstrated a comminuted fracture of the right side of the mandible and hyoid bone fracture at the junction between body and right greater cornua. The displaced fracture of hyoid bone and fullness in the pre-epiglottic space were noted, probably indicating some edema. The patient was transferred into ICU after treatment of emergency tracheostomy because the patient showed respiratory distress rapidly. When the patient was hospitalized in our emergency room, he complained of dysphagia and pain when swallowing. On examination of oral cavity, the presence of muscle wasting with fasciculation of the tongue was noted and the tongue deviates to the left side on protruding from the mouth. Pharyngolarygoscopy was performed to make sure that there was no evidence of progressive swelling and pharyngeal laceration. Results: The patient underwent surgical removal of dead and infected tissue from the wound and reconstruction of mandibular bony defect by iliac bone grafting. Hyoid bone fracture was managed conservatively with oral analgesics, soft diet and restricted movement. Hypoglossal nerve palsy was resolved within 7 weeks after trauma without complications. Conclusion: Closed hyoid bone fracture is usually uncomplicated and thus it can be treated conservatively. Surgical intervention for hyoid bone fracture is recommended for patient with airway compromise, pharyngeal perforation and painful symptoms which show no response to conservative care. Furthermore, since respiratory distress syndrome may develop quickly, close observation is required. Besides, hypoglossal nerve palsy is a rarely recognized complication of hyoid bone fracture.

• 대한의생명과학회지
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• 제14권1호
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• pp.13-18
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• 2008

Excessive alcohol consumption is associated with increased risks of many diseases including cancer. Individuals who regularly consume excessive quantities of alcohol have a greater risk of developing head and neck cancers such as esophageal, pharyngeal and oral cavity cancers if they are deficient in ALDH2 expression compared to normal populations. We evaluated lipid peroxidation in Aldh2 +/+ and Aldh2 -/- mice after they had been subjected to acute ethanol exposure. Malondialdehyde(MDA) level in liver tissue was evaluated as a biomarker of oxidative lipid peroxidation. Although the ethanol treatment did not increase the hepatic MDA level both in Aldh2 +/+ mice and in Aldh2 -/- mice, the MDA level was significant higher in the Aldh2 -/- mice than in the Aldh2 +/+ group. The MDA level was also significantly correlated with olive tail moment in blood and the level of 8-OHdG in liver tissue. This is a strong evidence to support our hypothesis that oxidative stress is more intense in Aldh2 -/- mice than in Aldh2 +/+ mice. Our results suggest that ALDH2-deficient individuals may be more susceptible than wild-type ALDH2 individuals to ethanol-mediated liver disease, including cancer.