In this work, a variety of polymer based jelly phantoms suitable for the hyperthermia operations to human organs was synthesized in order to confirm the possibility of auxiliary cancer therapy. Specifically, using an appropriate material composition including polyethylene, Jelly phantoms for brain was prepared and characterized their electrical properties suitable for the monitoring the effect of electromagnetic wave from code division multiple access (CDMA) and personal communication service (PCS) on the human body. In the future, after injection of ferromagnetic nanoparticle into the jelly phantoms, new approach to propose the cancer therapy can be anticipated by monitoring the degree of temperature rise in human body using the photograph of Infrared camera.
A-PET is a quad-head PET scanner developed for use in small-animal imaging. The dimensions of its volumetric field of view (FOV) are
Purpose: This study aimed to investigate the accuracy of head scatter factor (Sc) by applying a developed multi-leaf collimator (MLC) scatter source model for an unflattened photon beam. Methods: Sets of Sc values were measured for various jaw-defined square and rectangular fields and MLC-defined square fields for developing dual-source model (DSM) and MLC scatter model. A 6 MV unflattened photon beam has been used. Measurements were performed using a 0.125 cm3 cylindrical ionization chamber and a mini phantom. Then, the parameters of both models have been optimized, and Sc has been calculated. The DSM and MLC scatter models have been verified by comparing the calculated values to the three Sc set measurement values of the jaw-defined field and the two Sc set measurement values of MLC-defined fields used in the existing modeling, respectively. Results: For jaw-defined fields, the calculated Sc using the DSM was consistent with the measured Sc value. This demonstrates that the DSM was properly optimized and modeled for the measured values. For the MLC-defined fields, the accuracy between the calculated and measured Sc values with the addition of the MLC scatter source appeared to be high, but the only use of the DSM resulted in a significantly bigger differences. Conclusions: Both the DSM and MLC models could also be applied to an unflattened beam. When considering scattered radiation from the MLC by adding an MLC scatter source model, it showed a higher degree of agreement with the actual measured Sc value than when using only DSM in the same way as in previous studies.
Ultrafast ultrasound imaging has been applied to various imaging approaches, including shear wave elastography, ultrafast Doppler, and super-resolution imaging. However, these methods are still challenging in real-time implementation for three Dimension (3D) or portable applications because of their massive data rate required. In this paper, we proposed an adaptive quantization method that effectively reduces the data rate of large Radio Frequency (RF) data. In soft tissue, ultrasound backscatter signals require a high dynamic range, and thus typical quantization used in the current systems uses the quantization level of 10 bits to 14 bits. To alleviate the quantization level to expand the application of ultrafast ultrasound imaging, this study proposed a depth-sectional quantization approach that reduces the quantization errors. For quantitative evaluation, Field II simulations, phantom experiments, and in vivo imaging were conducted and CNR, spatial resolution, and SSIM values were compared with the proposed method and fixed quantization method. We demonstrated that our proposed method is capable of effectively reducing the quantization level down to 3-bit while minimizing the image quality degradation.
Background: The reference dose coefficients (DCs) of the International Commission on Radiological Protection (ICRP) have been widely used to estimate organ doses of individuals for risk assessments. This approach has been well accepted because individual anatomy data are usually unavailable, although dosimetric uncertainty exists due to the anatomical difference between the reference phantoms and the individuals. We attempted to quantify the individual variation of organ doses for photon external exposures by calculating and comparing organ DCs for 30 individuals against the ICRP reference DCs. Materials and Methods: We acquired computed tomography images from 30 patients in which eight organs (brain, breasts, liver, lungs, skeleton, skin, stomach, and urinary bladder) were segmented using the ImageJ software to create voxel phantoms. The phantoms were implemented into the Monte Carlo N-Particle 6 (MCNP6) code and then irradiated by broad parallel photon beams (10 keV to 10 MeV) at four directions (antero-posterior, postero-anterior, left-lateral, right-lateral) to calculate organ DCs. Results and Discussion: There was significant variation in organ doses due to the difference in anatomy among the individuals, especially in the kilovoltage region (e.g., <100 keV). For example, the red bone marrow doses at 0.01 MeV varied from 3 to 7 orders of the magnitude depending on the irradiation geometry. In contrast, in the megavoltage region (1-10 MeV), the individual variation of the organ doses was found to be negligibly small (differences <10%). It was also interesting to observe that the organ doses of the ICRP reference phantoms showed good agreement with the mean values of the organ doses among the patients in many cases. Conclusion: The results of this study would be informative to improve insights in individual-specific dosimetry. It should be extended to further studies in terms of many different aspects (e.g., other particles such as neutrons, other exposures such as internal exposures, and a larger number of individuals/patients) in the future.
Spatial resolution is still one of the most important parameters for evaluating image quality. In this study, we propose an approach to evaluate spatial resolution and MTF(Modulation Transfer Function) using bar target and Siemens star chart as a part of quality evaluation for UAV images. To this end, images were taken with a fixed-wing eBee(Canon IXUS) at the flight height of 130m and 260m, and with a rotary-wing GD-800(SONY NEX-5N) at flight height of 130m, with a Phantom 4 pro(FC 6310) at flight height of 90m, respectively. Spatial resolution was measured on orthoimages produced from this data. Results show that the resolution measured on the Siemens star and bar target was accurately degraded in proportion to the flight height regardless of the cameras. In the words, the spatial resolution of images taken at the same altitude of 130m with the eBee(Canon IXUS) and the GD-800(SONY NEX-5N) equipped with different cameras was the same as 4.1cm, and that of the eBee(Canon IXUS) at 260m was 8.0cm. In addition, the resolution measured on the Siemens star was about 1~2cm lower than that of the bar target at every flight height. The general tendency was also found to be proportional to the flight height in the measurement of the
In electrical impedance tomography (EIT), modified Newton Raphson (mNR) method is widely used inverse algorithm for static image reconstruction due to its convergence speed and estimation accuracy. The unknown conductivity distribution is estimated iteratively by minimizing a cost functional such that the residual error namely the difference in measured and calculated voltages is reduced. Although, mNR method has good estimation performance, EIT inverse problem still suffers from ill-conditioned and ill-posedness nature. To mitigate the ill-posedness, generally, regularization methods are adopted. The inverse solution is highly dependent on the choice of regularization parameter. In most cases, the regularization parameter has a constant value and is chosen based on experience or trail and error approach. In situations, when the internal distribution changes or with high measurement noise, the solution does not get converged with the use of constant regularization parameter. Therefore, in this paper, in order to improve the image reconstruction performance, we propose a new scheme to determine the regularization parameter. The regularization parameter is computed based on residual error and updated every iteration. The proposed scheme is tested with numerical simulations and laboratory phantom experiments. The results show an improved reconstruction performance when using the proposed regularization scheme as compared to constant regularization scheme.
Attenuation correction is important in producing quantitative positron emission tomography (PET) images. Conventionally, photon attenuation effects are corrected using transmission measurements performed before tracer administration. The pre-injection transmission measurement approach may require a time delay between transmission and emission scans for the tracer studies requiring a long uptake period, about 45 minutes for F-18 deoxyglucose study. The time delay will limit patient throughput and increase the likelihood of patient motion. A technique lot performing simultaneous transmission and emission scans (T+E method) after the tracer injection has been validated. The T+E method substracts the emission counts contaminating the transmission measurements to produce accurate attenuation correction coefficients. This method has been evaluated in experiments using a cylindrical phantom filled with background water (5750 cc) containing
The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70
The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70