• Title/Summary/Keyword: PhIP

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Impact and Rebounding Properties of Shoe Midsole with Temperature (온도변화에 따른 신발 중창용 발포체의 충격 및 반발특성)

  • Park, Cha-Cheol
    • Elastomers and Composites
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    • v.39 no.4
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    • pp.274-280
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    • 2004
  • Sorage modulus(G'), Impact and rebounding properties of polyurethane(PU), phylon(PH) and injection phylon(IP) foams were studied. The storage modulus of PU foam was dramatically increased with decreasing temperature. But the storage modulus(G') of IP and PH foams were not affected by temperature. The Impact force of PU foams was increased with decreasing temperature. But in the cases of IP and PH foams, the impact forces were not changed with temperature below $20^{\circ}C$. Impact farces of IP and PH foams were increased with the temperature above $20^{\circ}C$, but that of PU foam was not changed. Rebounding resilience of PU foam was lower than those of IP and PH foams from $-20^{\circ}C$ to $40^{\circ}C$.

The Effect of Repetitive Compression with Constant Stress on the Compressive Properties of Foams (일정 응력 반복압축이 발포체의 압축 특성에 미치는 영향)

  • Park, Cha-Cheol
    • Elastomers and Composites
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    • v.40 no.4
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    • pp.258-265
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    • 2005
  • To study the compressive stress, recovery force and permanent strain of foams for footwear midsole, polyurethane(PU), phylon(PH) and injection phylon(IP) foams were repetitively compressed with constant compressive stress. Maximum compressive stress of PU did not decrease with repetitive compression on the constant compressive stress, but that of IP largely decreased. Engineering strain of foams were formed by repetitively compressing the three types of foam. The engineering strain of PU was smaller than that of IP and PH. Compressive stress and recovery force of IP and PH at certain strain were decreased with repetitive compression, but that of PU was not noticeably changed.

The Effect of Repetitive Compression on the Fatigue Properties of Foam for Footwear Mid-sole (반복압축이 스포츠화용 발포체의 피로특성에 미치는 영향)

  • Park, Cha-Cheol
    • Elastomers and Composites
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    • v.40 no.4
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    • pp.242-248
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    • 2005
  • To study the fatigue properties of three type of foams for footwear midsole, polyurethane(PU), phylon(PH) and injection phylon(IP) foams were prepared with different hardnesses. Three types of foams were repetitively compressed for 50,000 cycles at 50 rpm. Cell shapes of foams were deformed with repetitive compression. The extent of cell deformation of IP was larger than those of PH and PU. Permanent strain of foam was made by repetitively compressing the foam, and the extent of IP was larger than those of PU and PH. Maximum compression forces of three types of the foams were decreased with the repetitive compression, and IP had the largest decrease in compression load of foam with compression. Decreases in maximum compression force of three types of foams were increased with increase of the hardness of foam.

The Effects of Baldness on the Compression-Rebounding Properties of Shoe Midsole (발포체의 경도가 신발 중창의 압축-반발 특성에 미치는 영향)

  • Park, Cho-Cheol
    • Elastomers and Composites
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    • v.39 no.3
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    • pp.186-192
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    • 2004
  • Compression and rebounding properties of IP(injection phylon), PH(phylon) and PU(polyurethane) foams were studied. The compression stress, rebounding stress, loss compression energy and storage compression energy of foams were decreased with increasing hardness of foams. The compression stress, loss compression energy of IP foams were lower than those of PH and PU. Rebounding stress and storage compression energy of PU foams were higher than those of IP and PH. The compression stress and rebounding of PH foam were lower than those of IP and PU.

SePH: Seamless Proxy-based Handoff Scheme in IP-based Heterogeneous Mobile Networks (이기종의 모바일 IP 네트워크에서 끊김없는 프록시 기반의 핸드오프 기법)

  • Lee, Seung-Hyun;Shin, Dong-Ryeol;Jeong, Jong-Pil
    • The KIPS Transactions:PartC
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    • v.19C no.1
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    • pp.71-82
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    • 2012
  • In Next Generation Wireless Networks (NGWN), lots of information, such as voice and video data, will be used in All-IP networks. It is important note that seamless service for users and handoff between heterogeneous networks must be taken into account in such environments. Therefore, in this paper, we propose a SePH(Seamless Proxy based Handoff) using PMIPv6-based proxy model which is enable to improve the performance of handoff in NGWN. The SePH can efficiently support seamless and IP-based mobility by reducing the search process. The performance results show that our proposed scheme outperforms in terms of QoS (Quality of Service) such as throughput, handoff latency, packet loss, and signaling overhead comparing to the existing schemes.

Elucidation of Anti-Tumor Initiator and Promoter Derived from Seaweed-4: Desmutagenic Principles of Ecklonia stolonifera Extracts against Carcinogenic Heterocyclic Amines (해조류 중의 Anti-Tumor Initiator 및 Promoter의 해석-4: 발암성 Heterocyclic Amine에 대한 곰피 추출물 중의 돌연변이원성 억제인자)

  • 김선봉;박영범;안종관;유승재;박덕천;김인수;박영호
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.27 no.3
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    • pp.537-542
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    • 1998
  • The present study was performed to elucidate desmutagenic principles from Ecklonia stolonifera extracts against 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine(PhIP) and 2-amino-3,8-dime-thylimidazo[4,5-f]duinoxaline(MeIQx) with Salmonella/mammalian-microsome mutagenicity test. Alginate, phenols, chlorophyll and carotenoids from Ecklonia stolonifera were extracted and their desmutagenicities were assayed. Alginate hydroysates showed desmutagenic activities against PhIP and MeIQx at high level dose. Phenol fractions and bromophenol showed desmutagenic activity of about MeIQx at high level dose. Phenol fractions and bromophenol showed desmutagenic activity of about 90% per 0.5mg against PhIP and MeIQx. Chlorophyllin among chlorophyll derivatives exhibited remarkable desmutagenic activities of 92.9% and 82.7% at 20uM against PhIP and MeIQx, respectively. Carotenoids, such as lutein and $\alpha$-cryptoxanthin isolated from Ecklonia stolonifera exerted also high desmutagenic activity. Major desmutagenic substances from Ecklonia stolonifera are considered to be chlorophyllin, phenols, lutein, $\alpha$-cryptoxanthin and low molecular alginates.

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Elucidation of Anti-tumor Initiator and Promoter Derived from Seaweed-2: Investigation of Seaweed Extracts Suppressing Mutagenic Activity of PhIP and MeIQx (해조류 중의 anti-tumor initiator 및 promoter의 해석-2: PhIP와 MeIQx의 돌연변이원성을 억제하는 해조 추출물 소재의 연구)

  • PARK Young-Beom;KIM In-Soo;YOO Sung-Jae;AHN Jong-Khan;LEE Tae-Gee;PARK Douck-Chon;KIM Seon-Bong
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.31 no.4
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    • pp.581-586
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    • 1998
  • The present study was conducted to prepare seaweed extracts suppressing mutagenic activity of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine ( PhIP ) ana 2-amino-3,8-dimethylmidazo[4,5-f]quinoxaline (MeIQx) derived from cooked meat produce. The tumor initiation activity of PhIP and MeIQx was assayed with Ames method using Salmonella typhimurium TA98 in the presence of S-9 mixtures before and after addition of methanol-solubles of seaweed, such as, Phaeophyta; Undaria pinnatifida, Ecklonia stolonifera Ecklonia cava, Laminaia japonica Sargassum fulvellum, Sargassum hornezi, Sargassum miyabei, Sargassum thunbergii, Agarum cribrosum and Hizikia fusifomis, Rhodophpei Porphyra yezoensis, Grateloupia eiliptiut Lomentraria catenata, Ploemium telfairiae and Glarilaria verrucosa, Chlorophyta; Codium fragile, Enteromorpha compresa and Ulva pertusa. Among seaweed tested, Phaeophyta was shown the higher desmutagenic activity than Rhodophyta and Chlorophyta. E. stolonifera, E. cava and S. miyabei, among Phaeophyta exerted the stronger desmutagenic activity (above $90\%$/2 mg). The ethyl acetate, diethyl ether and chlomform extracts except water extracts from E. stolonifera exhibited a high desmutagenic activity. The ethyl acetate extract of E. stolonifera which showed highest activity was fractionated with Sephadex LH20 column chromatography to give active fraction A-7, which showed desmutagenicity of $90\%$/mg against PhIP and $80\%$/mg against MeIQx. The active fraction had the absorbance at 207.7 and 232nm.

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Desmutagenicity of Tea Extracts from Green Tea, Oolong Tea and Black Tea (녹차, 오룡차 및 홍차 추출물의 돌연변이원성 억제작용)

  • 김선봉;여생규;김인수;안철우;박영호
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.24 no.1
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    • pp.160-168
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    • 1995
  • Desmutagenicities against 2-amino-1-methyl-6-phenylimidazo[4, 5-b] pyridine(PhIP) and 2-amino-3, 8-dimethylimidazo[4, 5-f]quinoxaline(MelQx) of tea extracts (steamed green tea, roasted green tea, oolong tea and black tea) were investigated. All the fractions obtained from tea extracts showed strong desmutagenic activity against PhIP and MeIQx toward S. typhimurium TA 98 in the presence of the S-9 mix. The crude catechin fraction exhibited the strongest desmutagenic activity. Among these tea extracts, black tea especially exhibited the strongest desmutagenic activity and the activity was 70.9~91.0% against PhIP and 92.2~98.8% against MelQx at a concentration(0.5~1.0mg/plate) for drinking. The activity of authentic catechins of (-)-EGC, (-)-EGCg, (-)-ECg and (-)-EC were 79.5%, 60.2%, 46.1% and 43.5% against PhIP, and were 52.3%, 11.6%, 8.2% and 22.1% against MelQx by addition of 1.0mg/plate, respectively. The desmutagenic activity was supposedly due to the (-)-EGCg, (-)-EGC and (-)-EC in tea polyphenols, and the browning materials. The desmutagenicity was stronger when mutagens were preincubated with S-9 mix after reaciton with black tea extracts than when preincubated with them after reaction with S-9 mix. The desmutagenicity of tea extracts was rather expressed by reacting directly with mutagens than by deactivating the activated forms of mutagens.

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MECHANISM OF CHEMOPREVENTION OF CARCINOGENIC HETEROCYCLIC AMINES BY TEA POLYPHENOLS AND COFFEE LIPIDS

  • Fred F. Kadlubar;Lin, Dong-xin;Daniel A. Casciano
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.10a
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    • pp.41-42
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    • 2001
  • The chemopreventive effect of tea against 2-amino-l-methyl-6-phenylimidazo[4, 5-b ]pyridine (PhIP)-DNA adduct formation and its mechanism were studied. Rats were exposed to freshly prepared aqueous extracts of green tea (3% w/v) as the sole source of drinking water for 10 days prior to administration with a single dose of PhIP (10 mg/kg body wt) by oral gavage. PhIP-DNA adducts in the liver, colon, heart, and lung were measured using the $^{32}$ P-postlabelling technique.(omitted)

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Protective Effects of Probiotic Lactobacillus rhamnosus IMC501 in Mice Treated with PhIP

  • Dominici, Luca;Villarini, Milena;Trotta, Francesca;Federici, Ermanno;Cenci, Giovanni;Moretti, Massimo
    • Journal of Microbiology and Biotechnology
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    • v.24 no.3
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    • pp.371-378
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    • 2014
  • The aim of the present study was to investigate the antigenotoxic properties of the probiotic Lactobacillus rhamnosus IMC501; DNA damage was induced by one representative food mutagen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Mice were treated orally with suspensions of lactobacilli for 10 days before administration of food mutagen. During the treatment, the abundance of lactobacilli in feces, as assessed by qPCR analysis, increased, whereas ${\beta}$-glucuronidase and N-acetyl-${\beta}$-glucosaminidase activities decreased. The extent of DNA damage was measured in colon and liver cells by comet assay. In colonocytes, diet supplementation with IMC501 resulted in a significant inhibition of DNA damage induced by PhIP. The results obtained in this in vitro study suggest that Lactobacillus rhamnosus IMC501 used as a dietary supplement can provide a useful integration of antimutagen food components of the normal diet, which are generally lower than the protective level.