• 제목/요약/키워드: Personalized Interaction

검색결과 108건 처리시간 0.024초

사용자 그룹별 과학기술정보 서비스 수요 분석 (Study on the Science & Technology Information Service Needs Corresponding to the Scientists and Engineers Group Characteristics)

  • 정혜주;윤정선
    • 정보관리연구
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    • 제43권4호
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    • pp.143-167
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    • 2012
  • 본 연구에서는 사용자 그룹별 과학기술정보 서비스 수요를 파악하기 위한 조사 분석을 실시하였다. 설문에서는 20가지 과학기술정보서비스에 대한 필요도, 인적교류를 위해 필요한 개인정보, 다른 사람과 공유할 수 있는 정보가 조사되었다. KOSEN 사용자 1,013명이 설문에 참여하였으며, 응답자의 소속기관, 직업, 최종학위, 연령에 따라 분산분석을 실시하였다. 빈도분석 결과 동향분석, 논문, 연구보고서, 특허, 지식질의, 채용정보, 프로젝트공고, 실험방법, 학회정보, 해외유학/Post-Doc정보에 대한 수요가 높았으며, 멘토링, 커뮤니티, 블로그 서비스를 제외한 모든 서비스가 사용자 그룹별 유의한 차이가 나타나는 것을 알 수 있었다. 과학기술자들이 상호 교류를 위해 필요하다고 생각하는 인적 정보로는 전문분야, 논문/연구실적, 경력사항, 소속기관, 직업, 최종학위, 학력사항 순으로 응답하였고 사용자 그룹별 필요하다고 생각하는 인적 정보는 부분적으로 차이가 있었다. 또한 응답자의 97%가 자신이 보유한 과학기술정보를 다른 사람들과 공유할 의사가 있다고 답변하였고 논문, 발표자료(ppt), 보고서, 실험방법, 이미지 순으로 공유 의사를 표시하였다. 본 연구 결과는 과학기술자들을 위한 사용자 중심 맞춤형 서비스를 개발하는데 유용한 정보로 활용될 수 있으며 향후 미래 과학기술정보 서비스의 방향을 설정하는 데에도 도움이 되리라 기대된다.

Whole genome MBD-seq and RRBS analyses reveal that hypermethylation of gastrointestinal hormone receptors is associated with gastric carcinogenesis

  • Kim, Hee-Jin;Kang, Tae-Wook;Haam, Keeok;Kim, Mirang;Kim, Seon-Kyu;Kim, Seon-Young;Lee, Sang-Il;Song, Kyu-Sang;Jeong, Hyun-Yong;Kim, Yong Sung
    • Experimental and Molecular Medicine
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    • 제50권12호
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    • pp.1.1-1.14
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    • 2018
  • DNA methylation is a regulatory mechanism in epigenetics that is frequently altered during human carcinogenesis. To detect critical methylation events associated with gastric cancer (GC), we compared three DNA methylomes from gastric mucosa (GM), intestinal metaplasia (IM), and gastric tumor (GT) cells that were microscopically dissected from an intestinal-type early gastric cancer (EGC) using methylated DNA binding domain sequencing (MBD-seq) and reduced representation bisulfite sequencing (RRBS) analysis. In this study, we focused on differentially methylated promoters (DMPs) that could be directly associated with gene expression. We detected 2,761 and 677 DMPs between the GT and GM by MBD-seq and RRBS, respectively, and for a total of 3,035 DMPs. Then, 514 (17%) of all DMPs were detected in the IM genome, which is a precancer of GC, supporting that some DMPs might represent an early event in gastric carcinogenesis. A pathway analysis of all DMPs demonstrated that 59 G protein-coupled receptor (GPCR) genes linked to the hypermethylated DMPs were significantly enriched in a neuroactive ligand-receptor interaction pathway. Furthermore, among the 59 GPCRs, six GI hormone receptor genes (NPY1R, PPYR1, PTGDR, PTGER2, PTGER3, and SSTR2) that play an inhibitory role in the secretion of gastrin or gastric acid were selected and validated as potential biomarkers for the diagnosis or prognosis of GC patients in two cohorts. These data suggest that the loss of function of gastrointestinal (GI) hormone receptors by promoter methylation may lead to gastric carcinogenesis because gastrin and gastric acid have been known to play a role in cell differentiation and carcinogenesis in the GI tract.

엣지-클라우드 협업 기반 인터랙티브 사이니지 제공 플랫폼 (A Platform Providing Interactive Signage Based on Edge-cloud Cooperation)

  • 문재원;금승우;이상원
    • 인터넷정보학회논문지
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    • 제20권2호
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    • pp.39-49
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    • 2019
  • IoT 데이터 분석 기술의 발전으로 사용자의 상황을 실시간으로 분석하고 분석에 따른 상황 기반 서비스 제공이 가능해졌다. 대부분의 디지털 사이니지는 정보를 일방향으로 제공하기 위한 홍보 목적으로 사용되었지만, 개별 사용자의 상황과 반응에 따라서 개인화된 콘텐츠를 제공하는 방향으로 진화할 것이다. 그러나 기존 인터랙티브 디지털 사이니지 플랫폼은 하드웨어 의존도가 높기 때문에 그 수정이나 응용이 어렵다. 제안하는 플랫폼은 광고 콘텐츠 등록 및 인터랙티브 사이니지 콘텐츠 생성이 용이하면서도 센서 분석 결과에 기반 하여 적시에 광고를 재생 가능하도록 주요 기능들을 클라우드와 엣지에 분리하여 모듈화 하였다. 엣지는 개인 데이터를 직접 처리하여 프라이버시 이슈를 최소화 하면서도 실시간 센서 데이터를 바탕으로 콘텍스트를 분석하여 빠르게 대응이 가능하다. 클라우드는 엣지보다 다수 작업자의 접근 및 관리가 용이하므로 다수가 함께 작업하는 사이니지 콘텐츠 생성은 클라우드 플랫폼에서 처리함으로써 접근성과 유연성을 높였다. 설계된 인터랙티브 사이니지 제공 플랫폼은 사이니지 콘텐츠를 제공하는 제공자와, 사이니지 콘텐츠를 이용하는 시청자 측면에서 테스트를 진행하였으며 콘텍스트 변화에 적시 대응하면서도 빠르게 인터랙티브 사이니지 콘텐츠를 구성할 수 있음을 확인하였다.

Systematic Target Screening Revealed That Tif302 Could Be an Off-Target of the Antifungal Terbinafine in Fission Yeast

  • Lee, Sol;Nam, Miyoung;Lee, Ah-Reum;Lee, Jaewoong;Woo, Jihye;Kang, Nam Sook;Balupuri, Anand;Lee, Minho;Kim, Seon-Young;Ro, Hyunju;Choi, Youn-Woong;Kim, Dong-Uk;Hoe, Kwang-Lae
    • Biomolecules & Therapeutics
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    • 제29권2호
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    • pp.234-247
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    • 2021
  • We used a heterozygous gene deletion library of fission yeasts comprising all essential and non-essential genes for a microarray screening of target genes of the antifungal terbinafine, which inhibits ergosterol synthesis via the Erg1 enzyme. We identified 14 heterozygous strains corresponding to 10 non-essential [7 ribosomal-protein (RP) coding genes, spt7, spt20, and elp2] and 4 essential genes (tif302, rpl2501, rpl31, and erg1). Expectedly, their erg1 mRNA and protein levels had decreased compared to the control strain SP286. When we studied the action mechanism of the non-essential target genes using cognate haploid deletion strains, knockout of SAGA-subunit genes caused a down-regulation in erg1 transcription compared to the control strain ED668. However, knockout of RP genes conferred no susceptibility to ergosterol-targeting antifungals. Surprisingly, the RP genes participated in the erg1 transcription as components of repressor complexes as observed in a comparison analysis of the experimental ratio of erg1 mRNA. To understand the action mechanism of the interaction between the drug and the novel essential target genes, we performed isobologram assays with terbinafine and econazole (or cycloheximide). Terbinafine susceptibility of the tif302 heterozygous strain was attributed to both decreased erg1 mRNA levels and inhibition of translation. Moreover, Tif302 was required for efficacy of both terbinafine and cycloheximide. Based on a molecular modeling analysis, terbinafine could directly bind to Tif302 in yeasts, suggesting Tif302 as a potential off-target of terbinafine. In conclusion, this genome-wide screening system can be harnessed for the identification and characterization of target genes under any condition of interest.

Are you a Machine or Human?: 소셜 로봇의 인간 유사성과 소비자 해석수준이 의인화에 미치는 영향 (Are you a Machine or Human?: The Effects of Human-likeness on Consumer Anthropomorphism Depending on Construal Level)

  • 이준식;박도형
    • 지능정보연구
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    • 제27권1호
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    • pp.129-149
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    • 2021
  • 최근 인간과 사회적으로 상호작용할 수 있는 소셜 로봇(Social Robot)에 대한 관심이 커지고 있다. ICT 기술 발전에 힘입어 소셜 로봇이 개인에게 맞춤형 서비스와 정서적 교감을 제공하기 쉬워졌으며, 현대의 사회문제들과 이로 인한 개인의 삶의 질 저하를 해소하기 위한 수단으로 소셜 로봇의 역할이 주목받고 있다. 소셜 로봇에 대한 관심에 힘입어 소셜 로봇 보급 또한 크게 늘고 있다. 많은 기업이 다양한 목표시장을 겨냥하기 위한 로봇 제품들을 시장에 선보이고 있으나, 현재까지 시장을 선도하는 명확한 흐름은 부재하다. 이에 따라 소셜 로봇의 디자인을 통해 로봇을 차별화하고자 하는 시도가 늘고 있다. 특히 의인화는 소셜 로봇 디자인에서 중요하게 연구되고 있으며, 소셜 로봇을 의인화하여 긍정적인 효과를 발현하려는 접근이 많이 시도되었다. 그러나 소셜 로봇에 대한 의인화가 형성되는 메커니즘을 체계적으로 설명하는 연구는 부족하다. 의인화에 대한 모호한 이해는 소셜 로봇의 의인화를 형성하기 위한 디자인 최적점의 도출을 어렵게 하고 있다. 본 연구는 소셜 로봇의 의인화가 형성되는 메커니즘을 검증하는 것을 목적으로 한다. 본 연구는 3×2 Mixed Design의 실험 연구를 통해 소셜 로봇의 인간 유사성(Human-likeness)과 개인의 해석수준(Construal Level)이 의인화 형성에 미치는 영향을 확인하였다. 의인화가 형성되는 메커니즘에 대한 6개의 연구 가설을 제시하고, 206명 표본의 데이터를 분석하여 가설을 검증하였다. 분석 결과 소셜 로봇의 인간 유사성 수준에 따라 로봇 의인화 수준이 높아지며, 소비자 해석수준에 따라 인간 유사성이 의인화에 미치는 영향이 다르게 나타남을 확인하였다. 본 연구는 소셜 로봇의 디자인 속성인 인간 유사성과 개인의 사고방식인 해석수준을 함께 고려하여 의인화가 형성되는 메커니즘을 설명하였다는 점에서 시사점이 있다. 본 연구의 결과를 소셜 로봇 의인화 형성을 위한 디자인 최적화의 기준으로 활용할 수 있을 것으로 기대한다.

스마트폰 위치기반 어플리케이션의 이용의도에 영향을 미치는 요인: 프라이버시 계산 모형의 적용 (Factors Influencing the Adoption of Location-Based Smartphone Applications: An Application of the Privacy Calculus Model)

  • 차훈상
    • Asia pacific journal of information systems
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    • 제22권4호
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    • pp.7-29
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    • 2012
  • Smartphone and its applications (i.e. apps) are increasingly penetrating consumer markets. According to a recent report from Korea Communications Commission, nearly 50% of mobile subscribers in South Korea are smartphone users that accounts for over 25 million people. In particular, the importance of smartphone has risen as a geospatially-aware device that provides various location-based services (LBS) equipped with GPS capability. The popular LBS include map and navigation, traffic and transportation updates, shopping and coupon services, and location-sensitive social network services. Overall, the emerging location-based smartphone apps (LBA) offer significant value by providing greater connectivity, personalization, and information and entertainment in a location-specific context. Conversely, the rapid growth of LBA and their benefits have been accompanied by concerns over the collection and dissemination of individual users' personal information through ongoing tracking of their location, identity, preferences, and social behaviors. The majority of LBA users tend to agree and consent to the LBA provider's terms and privacy policy on use of location data to get the immediate services. This tendency further increases the potential risks of unprotected exposure of personal information and serious invasion and breaches of individual privacy. To address the complex issues surrounding LBA particularly from the user's behavioral perspective, this study applied the privacy calculus model (PCM) to explore the factors that influence the adoption of LBA. According to PCM, consumers are engaged in a dynamic adjustment process in which privacy risks are weighted against benefits of information disclosure. Consistent with the principal notion of PCM, we investigated how individual users make a risk-benefit assessment under which personalized service and locatability act as benefit-side factors and information privacy risks act as a risk-side factor accompanying LBA adoption. In addition, we consider the moderating role of trust on the service providers in the prohibiting effects of privacy risks on user intention to adopt LBA. Further we include perceived ease of use and usefulness as additional constructs to examine whether the technology acceptance model (TAM) can be applied in the context of LBA adoption. The research model with ten (10) hypotheses was tested using data gathered from 98 respondents through a quasi-experimental survey method. During the survey, each participant was asked to navigate the website where the experimental simulation of a LBA allows the participant to purchase time-and-location sensitive discounted tickets for nearby stores. Structural equations modeling using partial least square validated the instrument and the proposed model. The results showed that six (6) out of ten (10) hypotheses were supported. On the subject of the core PCM, H2 (locatability ${\rightarrow}$ intention to use LBA) and H3 (privacy risks ${\rightarrow}$ intention to use LBA) were supported, while H1 (personalization ${\rightarrow}$ intention to use LBA) was not supported. Further, we could not any interaction effects (personalization X privacy risks, H4 & locatability X privacy risks, H5) on the intention to use LBA. In terms of privacy risks and trust, as mentioned above we found the significant negative influence from privacy risks on intention to use (H3), but positive influence from trust, which supported H6 (trust ${\rightarrow}$ intention to use LBA). The moderating effect of trust on the negative relationship between privacy risks and intention to use LBA was tested and confirmed by supporting H7 (privacy risks X trust ${\rightarrow}$ intention to use LBA). The two hypotheses regarding to the TAM, including H8 (perceived ease of use ${\rightarrow}$ perceived usefulness) and H9 (perceived ease of use ${\rightarrow}$ intention to use LBA) were supported; however, H10 (perceived effectiveness ${\rightarrow}$ intention to use LBA) was not supported. Results of this study offer the following key findings and implications. First the application of PCM was found to be a good analysis framework in the context of LBA adoption. Many of the hypotheses in the model were confirmed and the high value of $R^2$ (i.,e., 51%) indicated a good fit of the model. In particular, locatability and privacy risks are found to be the appropriate PCM-based antecedent variables. Second, the existence of moderating effect of trust on service provider suggests that the same marginal change in the level of privacy risks may differentially influence the intention to use LBA. That is, while the privacy risks increasingly become important social issues and will negatively influence the intention to use LBA, it is critical for LBA providers to build consumer trust and confidence to successfully mitigate this negative impact. Lastly, we could not find sufficient evidence that the intention to use LBA is influenced by perceived usefulness, which has been very well supported in most previous TAM research. This may suggest that more future research should examine the validity of applying TAM and further extend or modify it in the context of LBA or other similar smartphone apps.

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Video UGC 제작 동기와 행위 과정에 관한 이해: 구현의도이론 (Theory of Implementation Intentions)의 적용을 중심으로 (Understanding User Motivations and Behavioral Process in Creating Video UGC: Focus on Theory of Implementation Intentions)

  • 김형진;송세민;이호근
    • Asia pacific journal of information systems
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    • 제19권4호
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    • pp.125-148
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    • 2009
  • UGC(User Generated Contents) is emerging as the center of e-business in the web 2.0 era. The trend reflects changing roles of users in production and consumption of contents on websites and helps us to understand new strategies of websites such as web portals and social network websites. Nowadays, we consume contents created by other non-professional users for both utilitarian (e.g., knowledge) and hedonic values (e.g., fun). Also, contents produced by ourselves (e.g., photo, video) are posted on websites so that our friends, family, and even the public can consume those contents. This means that non-professionals, who used to be passive audience in the past, are now creating contents and share their UGCs with others in the Web. Accessible media, tools, and applications have also reduced difficulty and complexity in the process of creating contents. Realizing that users create plenty of materials which are very interesting to other people, media companies (i.e., web portals and social networking websites) are adjusting their strategies and business models accordingly. Increased demand of UGC may lead to website visits which are the source of benefits from advertising. Therefore, they put more efforts into making their websites open platforms where UGCs can be created and shared among users without technical and methodological difficulties. Many websites have increasingly adopted new technologies such as RSS and openAPI. Some have even changed the structure of web pages so that UGC can be seen several times to more visitors. This mainstream of UGCs on websites indicates that acquiring more UGCs and supporting participating users have become important things to media companies. Although those companies need to understand why general users have shown increasing interest in creating and posting contents and what is important to them in the process of productions, few research results exist in this area to address these issues. Also, behavioral process in creating video UGCs has not been explored enough for the public to fully understand it. With a solid theoretical background (i.e., theory of implementation intentions), parts of our proposed research model mirror the process of user behaviors in creating video contents, which consist of intention to upload, intention to edit, edit, and upload. In addition, in order to explain how those behavioral intentions are developed, we investigated influences of antecedents from three motivational perspectives (i.e., intrinsic, editing software-oriented, and website's network effect-oriented). First, from the intrinsic motivation perspective, we studied the roles of self-expression, enjoyment, and social attention in forming intention to edit with preferred editing software or in forming intention to upload video contents to preferred websites. Second, we explored the roles of editing software for non-professionals to edit video contents, in terms of how it makes production process easier and how it is useful in the process. Finally, from the website characteristic-oriented perspective, we investigated the role of a website's network externality as an antecedent of users' intention to upload to preferred websites. The rationale is that posting UGCs on websites are basically social-oriented behaviors; thus, users prefer a website with the high level of network externality for contents uploading. This study adopted a longitudinal research design; we emailed recipients twice with different questionnaires. Guided by invitation email including a link to web survey page, respondents answered most of questions except edit and upload at the first survey. They were asked to provide information about UGC editing software they mainly used and preferred website to upload edited contents, and then asked to answer related questions. For example, before answering questions regarding network externality, they individually had to declare the name of the website to which they would be willing to upload. At the end of the first survey, we asked if they agreed to participate in the corresponding survey in a month. During twenty days, 333 complete responses were gathered in the first survey. One month later, we emailed those recipients to ask for participation in the second survey. 185 of the 333 recipients (about 56 percentages) answered in the second survey. Personalized questionnaires were provided for them to remind the names of editing software and website that they reported in the first survey. They answered the degree of editing with the software and the degree of uploading video contents to the website for the past one month. To all recipients of the two surveys, exchange tickets for books (about 5,000~10,000 Korean Won) were provided according to the frequency of participations. PLS analysis shows that user behaviors in creating video contents are well explained by the theory of implementation intentions. In fact, intention to upload significantly influences intention to edit in the process of accomplishing the goal behavior, upload. These relationships show the behavioral process that has been unclear in users' creating video contents for uploading and also highlight important roles of editing in the process. Regarding the intrinsic motivations, the results illustrated that users are likely to edit their own video contents in order to express their own intrinsic traits such as thoughts and feelings. Also, their intention to upload contents in preferred website is formed because they want to attract much attention from others through contents reflecting themselves. This result well corresponds to the roles of the website characteristic, namely, network externality. Based on the PLS results, the network effect of a website has significant influence on users' intention to upload to the preferred website. This indicates that users with social attention motivations are likely to upload their video UGCs to a website whose network size is big enough to realize their motivations easily. Finally, regarding editing software characteristic-oriented motivations, making exclusively-provided editing software more user-friendly (i.e., easy of use, usefulness) plays an important role in leading to users' intention to edit. Our research contributes to both academic scholars and professionals. For researchers, our results show that the theory of implementation intentions is well applied to the video UGC context and very useful to explain the relationship between implementation intentions and goal behaviors. With the theory, this study theoretically and empirically confirmed that editing is a different and important behavior from uploading behavior, and we tested the behavioral process of ordinary users in creating video UGCs, focusing on significant motivational factors in each step. In addition, parts of our research model are also rooted in the solid theoretical background such as the technology acceptance model and the theory of network externality to explain the effects of UGC-related motivations. For practitioners, our results suggest that media companies need to restructure their websites so that users' needs for social interaction through UGC (e.g., self-expression, social attention) are well met. Also, we emphasize strategic importance of the network size of websites in leading non-professionals to upload video contents to the websites. Those websites need to find a way to utilize the network effects for acquiring more UGCs. Finally, we suggest that some ways to improve editing software be considered as a way to increase edit behavior which is a very important process leading to UGC uploading.

관계혜택과 브랜드 동일시의 역할에 관한 탐색적 연구: 브랜드 동일시의 매개역할을 중심으로 (An Exploratory Study on the Effects of Relational Benefits and Brand Identity : mediating effect of brand identity)

  • 방정혜;정지연;이은형;강현모
    • Asia Marketing Journal
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    • 제12권2호
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    • pp.155-175
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    • 2010
  • 본 연구는 관계혜택과 브랜드 동일시에 관한 탐색적 연구로서 충성도에 긍정적인 영향을 미치는 것으로 알려져 온 관계 혜택과 브랜드 동일시를 함께 고찰하려는 데에 목적이 있다. 관계 혜택과 브랜드 동일시는 각각 충성도와 유의한 관계가 있는 것으로 잘 알려져 왔으나, 그들 간의 관계를 함께 살펴본 연구는 거의 없는 실정이다. 한편으로는 카드산업에서 관계혜택이 중요한 전략적 요소인 동시에 최근에는 브랜드 개성과 이미지를 카드에 연결시키려는 시도를 하고 있다. 따라서 본 연구에서는 관계 혜택과 충성도와의 관계를 브랜드 동일시가 매개할 것으로 보고 그 영향을 탐색하였다. 결과적으로 관계혜택 차원, 즉 확신적 혜택과 특별대우혜택이 개인적 동일시와 사회적 동일시에 영향을 미치고, 개인적 동일시가 충성도에 영향을 미치는 것으로 나타났으며, 특히 확신적 혜택은 충성도에 직접적인 영향도 있는 것으로 나타났다.

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