• Title/Summary/Keyword: Persistent

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Patterns and Persistence of Pharmacotherapy for Children and Adolescents with Attention Deficit Hyperactivity Disorder in South Korea (국내 주의력결핍 과잉행동 장애 아동 및 청소년의 약물요법 패턴 및 지속성)

  • Lee, Kyeong Eun;Je, Nam Kyung
    • Korean Journal of Clinical Pharmacy
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    • v.28 no.3
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    • pp.216-223
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    • 2018
  • Objective: This study aimed to assess treatment persistence in Korean children and adolescents with attention deficit hyperactivity disorder (ADHD) and the factors influencing their adherence to ADHD pharmacotherapy. Methods: The study included patients between 6 and 18 years of age with ADHD who were taking various formulations of methylphenidate and atomoxetine on June 1, 2014. Patients were dichotomized as "persistent" or "non-persistent", depending on whether they continued ADHD therapy for 6 months (therapy persistence). We also investigated if the patients were taking the same medication(s) as before and also classified the patients as "medication persistent" or "non-persistent". Patient' characteristics were correlated with therapy persistence and medication persistence. Multiple logistic regression analyses were performed to assess potential risk factors for treatment persistence. Results: Overall, 3,317 patients were included in the analysis. A majority of patients were taking stimulants (82.0%), 16.2% were taking non-stimulants and 1.8% were taking a combination therapy of stimulants and non-stimulants. After 6 months, 2,290 patients (69.0%) continued to take medication for ADHD with 1,953 patients taking the same medication(s) as 6 months previously. Common positive factors for therapy persistence and medication persistence were identified as younger age, retardation, and developmental delay, and long-acting formulations of methylphenidate as either monotherapy or in a combination therapy may be used. Conclusion: ADHD medications were proven to improve academic performance and social skills of children. Collaboration between patients, parents, school staffs, and prescribers is required to improve the persistent use of ADHD medications.

Synthesis and luminescent properties of $Er^{3+}$ doped $CaZrO_3$ long persistent phosphors ($Er^{3+}$를 첨가한 $CaZrO_3$ 축광성 형광체의 합성 및 발광 특성 분석)

  • Park, Byeong-Seok;Choi, Jong-Koen
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.18 no.1
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    • pp.27-32
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    • 2008
  • Novel long persistent phosphors of $CaZrO_3:Er^{3+}$ have been synthesized by traditional solid state reaction method. The long persistent phosphor crystalline particles were characterized by the X-ray diffraction (XRD), photoluminescence spectrophotometer, thermoluminescence (TL) and luminance meter. The results reveal that the samples are composed of single $CaZrO_3$ phase. The broadband emission spectra of 446 nm peak and 550 nm peak was revealed by synthesized at high temperature in $N_2$ gas. Green long persistent phosphors have been observed in the sys_em for over 6 h after UV irradiation (254 nm). The main emission peak was ascribed to $Er^{3+}$ ions transition from $^5D_{5/2}{\rightarrow}^4F_{9/2},\;^2H_{12/2},\;^4S_{3/2}{\rightarrow}^4I_{13/2}\;and\;^2G_{9/2}{\rightarrow}^4I_{13/2}$, and the afterglow may be ascribed to the suitable trap centers in the $CaZrO_3$ host lattice.

Operation Plan for the Management of an Information Security System to Block the Attack Routes of Advanced Persistent Threats (지능형지속위협 공격경로차단 위한 정보보호시스템 운영관리 방안)

  • Ryu, Chang-Su
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2016.05a
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    • pp.759-761
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    • 2016
  • Recent changes in the information security environment have led to persistent attacks on intelligent assets such as cyber security breaches, leakage of confidential information, and global security threats. Since existing information security systems are not adequate for Advanced Persistent Threat; APT attacks, bypassing attacks, and attacks on encryption packets, therefore, continuous monitoring is required to detect and protect against such attacks. Accordingly, this paper suggests an operation plan for managing an information security system to block the attack routes of advanced persistent threats. This is achieved with identifying the valuable assets for prevention control by establishing information control policies through analyzing the vulnerability and risks to remove potential hazard, as well as constructing detection control through controlling access to servers and conducting surveillance on encrypted communication, and enabling intelligent violation of response by having corrective control through packet tagging, platform security, system backups, and recovery.

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A Stability of P-persistent MAC Scheme for Periodic Safety Messages with a Bayesian Game Model (베이지안 게임모델을 적용한 P-persistent MAC 기반 주기적 안정 메시지 전송 방법)

  • Kwon, YongHo;Rhee, Byung Ho
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.38B no.7
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    • pp.543-552
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    • 2013
  • For the safety messages in IEEE 802.11p/WAVE vehicles network environment, strict periodic beacon broadcasting requires status advertisement to assist the driver for safety. In crowded networks where beacon message are broadcasted at a high number of frequencies by many vehicles, which used for beacon sending, will be congested by the wireless medium due to the contention-window based IEEE 802.11p MAC. To resolve the congestion, we consider a MAC scheme based on slotted p-persistent CSMA as a simple non-cooperative Bayesian game which involves payoffs reflecting the attempt probability. Then, we derive Bayesian Nash Equilibrium (BNE) in a closed form. Using the BNE, we propose new congestion control algorithm to improve the performance of the beacon rate under saturation condition in IEEE 802.11p/WAVE vehicular networks. This algorithm explicitly computes packet delivery probability as a function of contention window (CW) size and number of vehicles. The proposed algorithm is validated against numerical simulation results to demonstrate its stability.

A Web Link Architecture Based on XRI Providing Persistent Link (영속적 링크를 제공하는 XRI 기반의 웹 링크 구조)

  • Jung, Eui-Hyun;Kim, Weon;Park, Chan-Ki
    • Journal of the Korea Society of Computer and Information
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    • v.13 no.5
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    • pp.247-253
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    • 2008
  • Web 2.0 and Semantic Web technology will be merged to be a next generation Web that leads presentation-oriented Web to data-centric Web. In the next generation Web. semantic processing. Web Platform, and data fusion are most important technology factors. Resolving the Link Rot is the one of the essential technologies to enable these features. The Link Rot causes not only simple annoyances to users but also more serious problems including data integrity. loss of knowledge. breach of service. and so forth. We have suggested a new XRI-based persistent Web link architecture to cure the Link Rot that has been considered as a deep-seated Problem of the Web. The Proposed architecture is based on the XRI suggested by OASIS and it is designed to support a persistent link by using URL rewriting. Since the architecture is designed as a server-side technology, it is superior to existing research especially in Interoperability. Transparency and Adoptability. In addition to this, the architecture provides a metadata identification to be used fer context-aware link resolution.

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Case Report of Korean Medical Treatment for a Patient with New Daily, Persistent Headache (신생 매일지속두통 환자에 대한 통합 한방치료 증례보고)

  • Yu, Sang-gu;Jang, Hye-yeon;Kim, Min-ju;Park, Cheol-u;Lee, Se-won;Jeon, Sang-woo
    • The Journal of Internal Korean Medicine
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    • v.42 no.2
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    • pp.67-74
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    • 2021
  • Objectives: This case report presents the effects of Korean medicine treatment in a patient with a new daily, persistent headache. Methods: A 58-year-old female patient with a new daily, persistent headache was treated with Yonggakgyodaeyeong-tang and Kyoungbang Chungsanggyuntong-tang granules, acupuncture, pharmacopuncture, and chuna therapy for 68 days. Headache and neck disability were assessed using a numeric rating scale (NRS), the headache impact test-6 (HIT-6), and the neck disability index (NDI). Results: After 68 days of treatment, headache was relieved, as measured by an NRS decrease from 7 to 4. In addition, the HIT score decreased from 30 to 18, and the NDI score decreased from 42 to 20. Conclusion: These results show that a daily, persistent headache can be relieved with Korean medicine treatment. However, additional well-designed studies are required to confirm these findings.

Modus Operandi: Irrigation of the Modified Eloesser Flap in Heterogeneous Suppurative Lung Pathologies

  • Vishnu, Rajkamal;Rai, Guruprasad D.;Kamath, Ganesh Sevagur;Kumara, Vijaya
    • Journal of Chest Surgery
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    • v.54 no.2
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    • pp.137-142
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    • 2021
  • Background: Refractory empyemas with collapsed lung and persistent bronchopleural fistulas pose significant problems to thoracic surgeons and impose a substantial burden in terms of morbidity and mortality. The modified Eloesser flap procedure is a useful palliative option for clearing infections. Herein, we present our experiences with the modified Eloesser flap procedure in mixed suppurative lung pathologies with a new technique of irrigation for persistent infection. Methods: A retrospective review was carried out of 56 patients who underwent the modified Eloesser flap with continuous irrigation at Katurba Medical College. These patients had severe morbidities and were not suitable for major thoracic resection surgery, and electively underwent modified Eloesser flap surgery. Regular follow-up was done at 1, 3, 6, and 12 months. Patients with persistent infections were treated with our continuous irrigation technique. Results: The most important finding was that all patients with active sputum acid-fast bacilli-positive findings became sputum smear-negative during the first month of follow-up. Half (50%) of the patients had a patent stoma. Eleven patients had persistent infections, necessitating continuous irrigation. The infection was fully cleared after 1 month in 9 patients, while 2 patients required second irrigation and continued to receive follow-up. In the remaining 50% of the patients, the stoma closed completely, and the lung expanded fully. Conclusion: The modified Eloesser flap is a simple procedure. In suppurative pathologies, infections were well controlled and the general condition of the patients improved. Our continuous irrigation method showed promising results in patients with persistent purulent discharge.

Policy for Selective Flushing of Smartphone Buffer Cache using Persistent Memory (영속 메모리를 이용한 스마트폰 버퍼 캐시의 선별적 플러시 정책)

  • Lim, Soojung;Bahn, Hyokyung
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.22 no.1
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    • pp.71-76
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    • 2022
  • Buffer cache bridges the performance gap between memory and storage, but its effectiveness is limited due to periodic flush, performed to prevent data loss in smartphones. This paper shows that selective flushing technique with small persistent memory can reduce the flushing overhead of smartphone buffer cache significantly. This is due to our I/O analysis of smartphone applications in that a certain hot data account for most of file writes, while a large proportion of file data incurs single-writes. The proposed selective flushing policy performs flushing to persistent memory for frequently updated data, and storage flushing is performed only for single-write data. This eliminates storage write traffic and also improves the space efficiency of persistent memory. Simulations with popular smartphone application I/O traces show that the proposed policy reduces write traffic to storage by 24.8% on average and up to 37.8%.

Implications for selecting persistent hot spots of schistosomiasis from community- and school-based surveys in Blue Nile, North Kordofan, and Sennar States, Sudan

  • Hassan Ahmed Hassan Ahmed Ismail;Seungman Cha;Yan Jin;Sung-Tae Hong
    • Parasites, Hosts and Diseases
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    • v.61 no.2
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    • pp.216-224
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    • 2023
  • In several schistosomiasis-endemic countries, the prevalence has remained high in some areas owing to reinfection despite repeated mass drug administration (MDA) interventions; these areas are referred to as persistent hot spots. Identifying hotspots is critical for interrupting transmission. This study aimed to determine an effective means of identifying persistent hot spots. First, we investigated the differences between Schistosoma haematobium and Schistosoma mansoni prevalence among school-aged children (SAC) estimated by a community-based survey, for which local key informants purposively selected communities, and a randomly sampled school-based survey. A total of 6,225 individuals residing in 60 villages in 8 districts of North Kordofan, Blue Nile, or Sennar States, Sudan participated in a community-based survey in March 2018. Additionally, the data of 3,959 students attending 71 schools in the same 8 districts were extracted from a nationwide school-based survey conducted in January 2017. The community-based survey identified 3 districts wherein the prevalence of S. haematobium or S. mansoni infection among SAC was significantly higher than that determined by the randomly sampled school survey (e.g., S. haematobium in the Sennar district: 10.8% vs. 1.1%, P<0.001). At the state level, the prevalence of schistosomiasis among SAC, as determined by the community-based survey, was consistently significantly higher than that determined by the school-based survey. Purposeful selection of villages or schools based on a history of MDA, latrine coverage, open defecation, and the prevalence of bloody urine improved the ability for identifying persistent hot spots.

Behavior of F shape non-persistent joint under experimental and numerical uniaxial compression test

  • Sarfarazi, Vahab;Asgari, Kaveh;Zarei, Meisam;Ghalam, Erfan Zarrin
    • Advances in concrete construction
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    • v.13 no.2
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    • pp.199-213
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    • 2022
  • Experimental and discrete element approaches were used to examine the effects of F shape non-persistent joints on the failure behaviour of concrete under uniaxial compressive test. concrete specimens with dimensions of 200 cm×200 cm×50 cm were provided. Within the specimen, F shape non-persistent joint consisting three joints were provided. The large joint length was 6 cm, and the length of two small joints were 2 cm. Vertical distance between two small joints change from 1.5 cm to 4.5 cm with increment of 1.5 cm. In constant joint lengths, the angle of large joint change from 0° to 90° with increments of 30°. Totally 12 different models were tested under compression test. The axial load rate on the model was 0.05 mm/min. Concurrent with experimental tests, numerical simulation (Particle flow code in two dimension) were performed on the models containing F shape non-persistent joint. Distance between small joints and joint angles were similar to experimental one. the results indicated that the failure process was mostly governed by both of the Distance between small joints and joint angles. The axial loading rate on the model was 0.05 mm/min. The compressive strengths of the samples were related to the fracture pattern and failure mechanism of the discontinuities. Furthermore, it was shown that the compressive behaviour of discontinuities is related to the number of the induced tensile cracks which are increased by increasing the joint angle. In the first, there were only a few acoustic emission (AE) hits in the initial stage of loading, and then AE hits rapidly grow before the applied stress reached its peak. Furthermore, a large number of AE hits accompanied every stress drop. Finally, the failure pattern and failure strength are similar in both approaches i.e., the experimental testing and the numerical simulation approaches.