• IMMUNE NETWORK
• /
• 제4권2호
• /
• pp.73-80
• /
• 2004

Viruses are obligate intracellular parasites which cause infection by invading and replicating within cells. The immune system has mechanisms which can attack the virus in extracellular and intracellular phase of life cycle, and which involve both non-specific and specific effectors. The survival of viruses depends on the survival of their hosts, and therefore the immune system and viruses have evolved together. Immune responses to viral infection may be variable depending on the site of infection, the mechanism of cell-to-cell spread of virus, physiology of the host, host genetic variation, and environmental condition. Viral infection of cells directly stimulates the production of interferons and they induce antiviral state in the surrounding cells. Complement system is also involved in the elimination of viruses and establishes the first line of defence with other non-specific immunity. During the course of viral infection, antibody is most effective at an early stage, especially before the virus enters its target cells. The virus- specific cytotoxic T lymphocytes are the principal effector cells in clearing established viral infections. But many viruses have resistant mechanism to host immune responses in every step of viral infection to cells. Some viruses have immune evasion mechanism and establish latency or persistency indefinitely. Furthermore antibodies to some viruses can enhance the disease by the second infection. Immune responses to viral infection are very different from those to bacterial infection.

• 한국환경보건학회지
• /
• 제39권4호
• /
• pp.346-353
• /
• 2013

Objectives: The goal of this study is to identify the distribution of the foliar fluorine content of vegetation surrounding the area where hydrofluoric acid was accidently released in Gumi, Gyeongsangbuk-do on September 27, 2012. In addition, it also aims to estimate the concentration of hydrogen fluoride in the air on the day of the accident. Methods: Samples of plant leaves were collected on October 7, 2012 within 1 km from the site where the accident occurred. These samples were analyzed for soluble fluorine ion with an ion selective electrode. The ambient concentration of hydrogen fluoride was calculated using the fluoride content in the plant via the dose-rate equation (${\Delta}F$=KCT). Results: The arithmetic and geometric means of the concentrations were 2158.2 and 1183.7mg F $kg^{-1}$ for leaves and, 2.4 and 1.1 ppm HF for the air, respectively. The highest concentration of hydrogen fluoride in the air was 14.7 ppm, which is higher than the maximum concentration reported by the government (1 ppm) and the exposure limit (ceiling, 3 ppm). The concentrations of both fluorine and hydrogen fluoride decreased with increasing distance from the accident site and showed a significant decrease outside of a 500m radius from the site (p <0.05). Conclusions: The area around the accident site was highly polluted with hydrogen fluoride according to the results of this study. Considering the persistency of hydrogen fluoride in the environment, long-term monitoring and environmental impact assessment should be pursued.

• Journal of Advanced Marine Engineering and Technology
• /
• 제38권8호
• /
• pp.1010-1020
• /
• 2014

Ballast water effluent treated by an electrolytic method contains reactive chlorine species and disinfection by-products (DBPs). In this study, we conducted whole effluent toxicity (WET) testing and ecological risk assessment (ERA) to investigate its ecotoxicological effects on marine environment. WET testing was carried out for three marine pelagic organisms, i.e., diatom Skeletonema costatum, rotifer Brachionus plicatilis and fish Paralichthys olivaceus. The biological toxicity test revealed that S. costatum was the only organism that showed apparent toxicity to the effluent; it showed no observed effect concentration (NOEC), lowest observable effect concentration (LOEC) and effect concentration of 50% (EC50) values of 12.5%, 25.0% and 83.3%, respectively, at brackish water condition. In contrast, it showed insignificant toxicity at seawater condition. B. plicatilis and P. olivaceus also showed no toxicities to the effluent at the both salinity conditions. Meanwhile, chemical analysis revealed that the ballast water effluent contained total residual oxidants (TROs) below $0.03{\mu}g/L$ and a total of 20 DBPs including bromate, volatile halogenated organic compounds (VOCs), halogenated acetonitriles (HANs), halogenated acetic acids (HAAs) and chloropicrin. Based on ERA, the 20 DBPs were not considered to have persistency, bioaccumulation and toxicity (PBT) properties. Except monobromoacetic acid, the ratio of predicted environmental concentration (PEC) to predicted no effect concentration (PNEC) of the other 19 DBPs did not exceed 1. Thus, our results of WET testing and ERA indicated that the ballast water effluent treated by electrolysis and subsequently neutralization was considered to have no adverse impacts on marine environment.

• Communications for Statistical Applications and Methods
• /
• 제16권4호
• /
• pp.605-614
• /
• 2009

본 논문에서는 금융시계열자료를 분석하는데 있어서 비대칭 변동성과 지속성효과를 가지는 시계열 자료에 적합한 모형인 I-TGARCH를 제시하였다. 국내 금융시계열 자료를 바탕으로 I-TGARCH의 적합성을 검증하기 위해 기존연구에서 많이 쓰이고 있는 TGARCH, IGARCH, EGARCH 모형과 함께 분석하여 비교하였다. 그 결과, I-TGARCH모형이 경제 위기의 영향으로 변동성이 커진 현재의 주가 분석에 적합하다는 사실을 알 수 있었다. 특히, 비대칭적 변동성의 특징을 관찰하기 위해 News impact curve를 이용해서 호재와 악재에 다르게 반응하는 주가변동에 대해서 알아본 결과, 대부분의 주가변동이 비대칭적인 경향을 보이고 있다는 사실을 관찰했다. 또한, 실제 일별수익율 데이터를 I-TGARCH 모형에 적합시키고 모형이 얼마나 효율적인지를 검정하였다. I-TGARCH의 적합성을 검증하기 위해 VaR의 사후검정을 이용하였다. 그 결과 대부분의 금융시계열이 I-TGARCH가 다른 비교모형 보다 우수하거나 비슷한 것으로 검증되었다. 이는 변동성의 비대칭성을 고려한 TGARCH에서 지속-변동성 효과(persistent effect) 또한 존재할 수 있다는 사실을 금융시계열자료를 통해 알 수 있었다.

• 한국인터넷방송통신학회논문지
• /
• 제16권1호
• /
• pp.177-182
• /
• 2016

지오펜스는 사용자의 행동을 기반으로 상황을 주도적으로 유발할 수 있는 PoI(관심 지점, Point of Interest)의 지리학적인 측면을 묘사하기 위한 일반적인 개념이다. 그러나, 일시적인 사건이나 사고, 전염병 등의 감염성 바이러스의 지역적 확산이지만 일시적인 환경에 반영하는 PoI에는 지오펜스를 지속적으로 유지할 필요가 없다. 그러므로 본 논문에서는 PoI를 지원하기 위한 지오펜스 플랫폼 TemG를 제안한다. 제안된 TemG는 지오펜스의 기본적인 상황 인식 기능에 한시성을 갖도록 시간을 제한적으로 적용하는 속성을 부여함으로써 지오펜스의 지속성을 보장한다. 향후에는 TemG가 IoT를 위한 HPS(Hybrid Positioning System)와 확장되는 것이 필요하다.

• Asian-Australasian Journal of Animal Sciences
• /
• 제17권12호
• /
• pp.1689-1694
• /
• 2004

This study was conducted to develop a novel adjustment factors for 305 days using 138,103 lactation records and 1,770,764 daily records, which were based on environmental circumstances such as herd year, season, age at calving, dry period and lactating stages. The present study showed that the change of persistency of cows at the first parity from total lactacting characteristics was slowly processed, while it was rapidly changed in cows at the second parity stage. Particularly, there was an outstanding difference between the first and second parity cows. Milk yield and composition increased as the age at calving was increased. In addition, milk yield and composition were higher at the first parity on fall compared with others, and those were higher at the more than second parity on fall and winter compared with other parity stages and seasons. The cow of dry group was included into lactating records of more than second parity stage. The data indicated that optimal results arose from 45-70 days of dry period. Milk yield was decreased when dry period was longer or shorter than 45-70 days. The lactating days were divided into 17, 28 and 38 stages to compare the multiplicative correction factors. The factor was effective at 28 stages on the first parity. The total correlation coefficients were 0.93832, 0.95058 and 0.95076 at the present correction factor, 17 stage and 28 stage, respectively. At second parity, the factor was higher in dry group 1 and 3 at 17 stage, and it was higher in dry group 2 at 28 stage compared with others. Therefore, the present study showed that the percent squared bias (PSB), which was calculated from the novel correction factor, was better than previously used correction factors. Also, the present study indicated that the bias of the novel correction factor was improved, and this factor could be more accurate compared with others.

• 한국멀티미디어학회논문지
• /
• 제19권7호
• /
• pp.1179-1187
• /
• 2016

Through the rapid development of latest hardware technology, high performance as well as miniaturized size is the essentials of embedded system to meet various requirements from the society. It raises possibilities of genuine realization of IoT environment whose size and battery must be considered. However, the limitation of battery persistency and capacity restricts the long battery life time for guaranteeing real-time system. To maximize battery life time, low power technology which lowers the power consumption should be highly required. Previous researches mostly highlighted improving one single type of memory to increase ones efficiency. In this paper, reversely, considering multiple memories to optimize whole memory system is the following step for the efficient low power embedded system. Regarding to that fact, this paper suggests the study of volatile memory, whose capacity is relatively smaller but much low-powered, and non-volatile memory, which do not consume any standby power to keep data, to maximize the efficiency of the system. By executing function in specific memories, non-volatile and volatile memory, the quantitative analysis of power consumption is progressed. In spite of the opportunity cost of all of theses extra works to locate function in volatile memory, higher efficiencies of both power and energy are clearly identified compared to operating single non-volatile memory.

• 대한원격탐사학회:학술대회논문집
• /
• 대한원격탐사학회 1998년도 Proceedings of International Symposium on Remote Sensing
• /
• pp.236-241
• /
• 1998

The NOAA AVHRR remote sense SST data, collected by the National Fisheries Research and Development Institute (NFRDI), are analyzed in order to understand the spatial and temporal distributions of SST in the seas adjacent to Korea. Our study is based on 10-day SST images during last 7 years (1991-1997). For a time series analysis of multiple 557 images, all of images must be aligned exactly at the same position by adjusting the scales and positions of each SST image. We devised an algorithm which yields automatic detections of cloud pixels from multiple SST images. The cloud detection algorithm is based on a physical constraint that SST anomalies in the ocean do not exceed certain limits (we used $\pm$ 3$^{\circ}C$ as a criterion of SST anomalies). The remote sense SST data are tuned by comparing remote sense data with observed SST at coastal stations. Seasonal variations of SST are studied by harmonic fit of SST normals at each pixel. The SST anomalies are studied by statistical method. We found that the SST anomalies are rather persistent with time scales between 1 and 2 months. Utilizing the persistency of SST anomalies, we devised an algorithm for a prediction of future SST Model fit of SST anomalies to the Markov process model yields that autoregression coefficients of SST anomalies during a time elapse of 10 days are between 0.5 and 0.7. We plan to improve our algorithms of automatic cloud pixel detection and prediction of future SST. Our algorithm is expected to be incorporated to the operational real time service of SST around Korea.

• 한국초지조사료학회지
• /
• 제11권1호
• /
• pp.1-5
• /
• 1991

Tall fescue(Festuca amndinacea Schreb.) is a productive pasture grass that is widely adapted to the soil and climate of Korea. It is regarded, however, as relatively low in palatability and nutritive value. On the other hand, Italian ryegrass(lo1ium rnultz$om Lam.) is highly nutritious and palatable, but is essentially weak in cold tolerance. Numerous investigators have succeeded in producing hybrids between Lolium spp. and Festuca spp. but no improved varieties have resulted. Therefore, intergeneric hybridization of Italian ryegrass with tall fescue is employed in 1984 to improve the adaptive and cold resistance quality of Italian ryegrass. In the mean time, F1-hybrid plants obtained by crossing Italian ryegrass x tall fescue were observed in open field. The results are summarized as follows: 1. Leaf-size and silica cell hair were intermediate between the types of parents but the shape of auricle tended to show Italian ryegrass and auricle-cilia to show tall fescue. 2. Roots of $F_1$-hybrid plants were mainly distributed at top soil and did not produced florescence material. 3. Head type of hybrids was intermediate between the types of parents but ray length was somewhat less than the length of tall fescue ray. Typical Italian ryegrass or tall fescue-like phenotypes were not observed. 4. Anthers of $F_1$-hybrid plants were formed but pollen were not formed. Even though pollen were formed, they were all empty. 5. Hybrid plants were more winterhardy and summer persistency than Italian ryegrass. They showed a equivalent growth to Italian ryegrass in spring and to tall fescue in summer. 6. Chromosome of $F_1$-hybrids was allopolyploid(2n=4~=28) and all $F_1$-hybrid plants were sterile.

• 응용통계연구
• /
• 제26권6호
• /
• pp.987-998
• /
• 2013

이 논문에서는 한국의 대기질을 결정하는 중요한 수치인 미세먼지(PM10)에 대한 통계적 고찰을 한다. 2011년 매시 관찰된 자료 분석을 토대로 미세먼지가 매우 높은 시차에서도 강한 양의 상관관계를 가지는 장기 종속 시계열의 특징을 보임을 밝힌다. 또한 주변분포는 꼬리가 두터운 모형으로서 로그-정규분포보다는 일반화 파레토 분포가 훨씬 더 자료를 잘 적합함을 보인다. 하지만 이러한 높은 상관관계는 종종 단순한 평균변화 모형에 의한 그럴듯싸한 가짜 효과에 기인하기도 하여 통계모형을 세우는데 많은 혼동을 준다. 따라서 이 논문에서는 강한 종속성이 장기 종속 시계열에 의한 것인지 아니면 비정상 평균변화에 의한 것인지 근본적인 물리적 모형에 대한 논의를 통계적인 가설 검정을 통해 살펴본다. 그 결과 미세먼지의 강한 종속성은 구조변화에의한 착시 효과임을 밝힌다.