• Animal cells and systems
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• 제15권2호
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• pp.123-130
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• 2011

Transient receptor potential melastatin 7 (TRPM7) channels are novel $Ca^{2+}$-permeable non-selective cation channels that are ubiquitously expressed. Activation of TRPM7 channels has been shown to be involved in the survival of gastric cancer cells. Here we show evidence suggesting that TRPM7 channels play an important role in $Zn^{2+}$- mediated cellular injury. Using a combination of electrophysiology, pharmacological analysis, small interfering RNA (siRNA) methods and cell death assays, we showed that activation of TRPM7 channels augmented $Zn^{2+}$-induced apoptosis of AGS cells, the most common human gastric adenocarcinoma cell line. The $Zn^{2+}$-mediated cytotoxicity was inhibited by the non-specific TRPM7 blockers $Gd^{3+}$ or 2 aminoethoxydiphenyl borate (2-APB) and TRPM7 specific siRNA. In addition, we showed that overexpression of TRPM7 channels in HEK293 cells increased $Zn^{2+}$- induced cell injury. Thus, TRPM7 channels may represent a novel target for physiological disorders where $Zn^{2+}$ toxicity plays an important role.

• 한국염색가공학회지
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• 제30권4호
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• pp.227-236
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• 2018

As consciousness of safety becomes an important social issue, the demand for protective clothing is increasing. Conventional flame-retardant cotton working wear has low durability, and working wear with m-aramid fibers are stiff, heavy, less permeable, and expensive. In this study, recycled m-aramid and cotton have been blended to produce woven fabric of different compositions to enhance high performance and comfort to solve aforementioned problems. The fabrics were analyzed according to constituents and various structural factors. Mechanical properties were measured using KES-FB system. The measured thermal properties are TGA, $Q_{max}$, TPP and RPP. Fabric with polyurethane yarn covered by m-aramid/cotton spun yarn is observed to have good wearability. The fabric of open end spun yarn showed more stiffness than that of ring spun yarn. The sample with the high count of yarn has more smooth surface. In addition, high m-aramid content fabric is considered to have relatively high stiffness when using as clothing. In TGA the fabric with higher m-aramid content showed more stable decomposition behavior. The fabric having rough surface showed lower heat transfer properties in $Q_{max}$. The influence of the fabric thickness was important in convection and radiant heat test.

• 한국기후변화학회지
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• 제5권3호
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• pp.257-266
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• 2014

This study aims to understand abnormal climate caused by impacts of climate change and to suggest the direction of urban planning focusing on adaptation to climate change. The study consists of theory consideration and case study(Chicago, Philadelphia, Seattle). As a result, the main impacts of climate change faced by urban areas are heat wave, precipitation, and drought. To prevent these impacts, it is important to prepare methods of urban planning as followings: planning for land use, park and green considering the climate patterns, establishing and managing water resources systems similar to the nature, securing renewable energy resources, and transportation facilities and exterior space with proof against climate. It is especially necessary to introduce infrastructures related to storm water, green roof, shading tree planting, green space, and permeable pavement. Finally, in order to realize urban planning for adaptation to climate change, it is needed to make the detailed and specific goal and strategy for the climate change adaptation plan and to extend the scope from the goals to an action plan, a detailed plan, and a design guideline.

• Environmental Engineering Research
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• 제24권3호
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• pp.456-462
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• 2019

Hydrocarbon contamination is among the most challenging problems in soil remediation. Electrokinetic method can be a promising method to remediate hydrocarbon-contaminated soils. Electrokinetic method consists of different transport phenomena including electro-migration, electrophoresis, and electroosmotic flow. Electroosmotic flow is the main transport phenomenon for hydrocarbon removal in soil porous media. However, the main component of hydrocarbons is the hydrophobic organic which indicates low water solubility; therefore, it makes the electroosmotic flow less effective. The objective of the present study is to enhance electrokinetic remediation of diesel-contaminated silty sand by increasing the solubility of the hydrocarbons in the soil and then increase the efficiency. For this purpose, sodium dodecyl sulfate (SDS) was used as a catholyte. In this content, SDS 0.05 M was used as catholyte and $Na_2SO_4$ 0.1 M was used as an anolyte. Low (1 V/cm) and high (2 V/cm) voltage gradients were used in periodic and continuous forms. The best removal efficiency was observed for high voltage gradient (2 V/cm) in a periodic form, which was 63.86. This result showed that a combination of periodic voltage application in addition to the employment of SDS is an effective method for hydrocarbon removal from low permeable sand.

• 한국재료학회지
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• 제29권5호
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• pp.297-303
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• 2019

A triple-layered $PMMA/Ni_{64}Zr_{36}/PDMS$ hydrogen gas sensor using hydrogen permeable alloy and flexible polymer layers is fabricated through spin coating and DC-magnetron sputtering. PDMS(polydimethylsiloxane) is used as a flexible substrate and PMMA(polymethylmethacrylate) thin film is deposited onto the $Ni_{64}Zr_{36}$ alloy layer to give a high hydrogen-selectivity to the sensor. The measured hydrogen sensing ability and response time of the fabricated sensor at high hydrogen concentration of 99.9 % show a 20 % change in electrical resistance, which is superior to conventional Pd-based hydrogen sensors, which are difficult to use in high hydrogen concentration environments. At a hydrogen concentration of 5 %, the resistance of electricity is about 1.4 %, which is an electrical resistance similar to that of the $Pd_{77}Ag_{23}$ sensor. Despite using low cost $Ni_{64}Zr_{36}$ alloy as the main sensing element, performance similar to that of existing Pd sensors is obtained in a highly concentrated hydrogen atmosphere. By improving the sensitivity of the hydrogen detection through optimization including of the thickness of each layer and the composition of Ni-Zr alloy thin film, the proposed Ni-Zr-based hydrogen sensor can replace Pd-based hydrogen sensors.

• 한국포장학회지
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• 제27권1호
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• pp.35-40
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• 2021

Calcium hydroxide (CH) reacts with CO2 to produce moisture, and sodium carbonate (SC) reacts with CO2 in the presence of moisture. Using these different characteristics of these two reactants, a CH/SC mixture of CO2 absorber tuned for kimchi ripening to produce CO2 in a flexible package was selected. A ratio of CH:SC (1:2) in highly gas permeable microporous spunbonded film (Tyvek) sachet was found to be appropriate for delayed and consistent CO2 absorption useful for kimchi package. Addition of superabsorbent polymer (SAP) as moisture buffer was helpful for boosting the consistency of CO2 absorption. In a package of 0.5 kg kimchi at 10℃, the sachet consisting of 0.794 g of CH + 2.276 g of SC + 0.4 g of SAP suppressed its volume expansion and maintained a suitable range of CO2 partial pressure (PCO2) steadily inside. These optimal conditions may vary depending on the type and salinity of kimchi, storage and distribution temperature, and the material and area of the absorber sachet. This study showed a potential of mixture CO2 absorber to be tuned for CO2 producing packaged kimchi for the purpose of keeping consistent PCO2 at tolerable volume expansion.

• 한국기계가공학회지
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• 제20권8호
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• pp.18-24
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• 2021

Polymers, polymer compounds, are very moldable at low temperatures and have good strength against weight, and hence, are often used in the interior and exterior materials of cars. Owing to the increasing environmental problems, emission regulations have become stricter, which has increased the use of lightweight polymers as substitutes for metal materials. Therefore, as the use of polymer increases, extensive research is being conducted on the bonding technology of polymers, such as polyurethane and epoxy. However, the increased cost and environmental pollution by adhesives caused by the polymer manufacturing plant depend on the chemical composition or the manufacturer's mix ratio. To compensate for this issue, a laser beam is irradiated through a highly permeable polymer (PC) placed on top of an absorbent polymer (ABS) to transfer the laser output to the ABS polymer and fuse them at the interface. Moreover, enabling laser penetrating bonding by placing a stainless steel wire mesh between the two polymers can achieve improved bonding strength compared to conventional heterogeneous polymer bonding.

• 영어영문학
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• 제64권1호
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• pp.77-94
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• 2018

This paper examines William and Ellen Craft's Running a Thousand Miles for Freedom (1860)-a narrative of the enslaved couple's escape from Macon to Philadelphia in the guise of a white male master and a colored slave. Expanding Judith Adler's notion of "travel as performed art," my reading of Running focuses on the Crafts' stratagems of transvestism-crossing boundaries not only of gender, but also of race, class, and disability. If travel can be understood as a form of performed art, then why not address a traveler as a performance artist? I present William and Ellen's role-playing in Running as performers of crossing borders and categories, or, as "fugitive performers," since the couple's story never reaches its final arrival but narrates an eternal run-away, far more than "a thousand miles to freedom." Using social stereotypes of race and gender to disguise, William and Ellen plot, write, choreograph, play, and recite on the moving stages and manipulate the others-especially white American audiences-who accompany the couple's run-away and those who were responsible for the cultural drama-a tragedy of American slavery. Becoming "fugitive performers," William and Ellen de-essentialize and debunk the nineteenth-century America's firm belief in distinct color line between black and white, and in the high yet unstable bars between male / female, abled / disabled, master / slave, and freedom / slavery. The Crafts alert their contemporaries and readers by presenting the complex and permeable boundaries of race, gender, class, social and cultural ability.

• 한국발생생물학회지:발생과생식
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• 제25권1호
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• pp.1-14
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• 2021

The Syrian (golden) hamsters are seasonal breeders whose reproductive functions are active in summer and inactive in winter. In experimental facility mimicking winter climate, short photoperiod (SP) induces gonadal regression. The blood-testis barrier (BTB) of the sexually involuted animals have been reported to be permeable, allowing developing germ cells to be engulfed or sloughed off the epithelium of the seminiferous tubules. The expressions of genes related to the tight junction composing of BTB were investigated in the reproductive active and inactive testes. Claudin-11, occludin, and junctional adhesion molecule (JAM) were definitely expressed in the active testes but not discernably detected in the inactive testes. And spermatozoa (sperm) were observed in the whole lengths of epididymides in the active testes. They were witnessed in only cauda region of the epididymides but not in caput and corpus regions in animals with the inactive testes. The results imply that the disorganization of BTB is associated with the testicular regression. The developing germ cells are swallowed into the Sertoli cells or travel into the lumen, as supported by the presence of the sperm delayed in the last region of the epididymis. These outcomes suggest that both apoptosis and desquamation are the processes that eliminate the germ cells during the regressing stage in the Syrian hamsters.

• Advances in nano research
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• 제10권3호
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• pp.263-270
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• 2021

The present manuscript focuses the effects of suction on the flow of the dusty fluid along permeable exponentially stretching cylinder. Derived PDEs for this work are changed into ODEs by adopting right transformations. Numerical procedure is carried out for the obtained resultant equations by Shooting Technique in accordance with Runge-Kutta (RK-6) technique. Obtained results for the parameters namely, particle interaction parameter, suction parameter and Reynold number parameters are probed thoroughly. Some salient points are: (a) Fluid velocity decreases and the dust phase velocity rises for the higher values of particle interaction parameter; (b) more suction produces retarding velocities for both the phases; (c) high Reynold number slows down the fluid velocity while the speed of dust phase and (d) skin friction coefficient goes high for all these parameters.