• 제목/요약/키워드: Permanent Death

검색결과 57건 처리시간 0.027초

기관삽관후 발생한 기관협착증의 외과적 치료 (Surgical Treatment of Postintubation Tracheal Stenosis)

  • 김치경
    • 대한기관식도과학회지
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    • 제3권1호
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    • pp.61-69
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    • 1997
  • A total of 55 patients underwent surgical managements for postintubation tracheal stenosis from July 1975 through March 1997. All but 8 had received ventilatory assistance. The patients had S cuff lesions, 17 stoma lesions, 7 at both levels, 5 at subglottic lesions. Thirty two patients underwent the sleeve tracheal resection and end-to-end anastomosis. Five patients performed a wedge resection and end-to-end anastomosis. Twenty two patients received the Montgomery T-tube for relief of airway obstruction. Simple excision of granulation tissue was done in 7 patients. Rethi procedures(anterior division of cricoid cartilage, partial wedge resection of lower thyroid cartilage and T-tube molding) were performed in 2 subglottic stenosis patients. And the other subglottic patient was received permanent tracheal fenestration at 1975. The tracheoesophageal fistula patient was done sleeve tracheal resection and end-to-end anastomosis with interrupted double layer closure of esophageal fistula site. Cervical approach was used in 49 cases, cervicomediastinal in 13 cases and median stemotomy In 6 cases. Techniques for obtaining tension-free anastomosis included a cervical neck flexion(15-30$^{\circ}$) in all sleeve resection patients and laryngeal release in one. The length of resection was 1.5 to 5.0 on A total of 41 patients(74.5%) had good(24 patients) or satisfactory(17 patients) results. But in ten cases, the restenosis of anastomosis site which is the most common complication was developed Two of them underwent a second reconstruction and 8 patients required T-tube insertion for airway maintenance. Three patients(5.4%) died. The causes of death were tracheo-innominate artery fistula(2) and sudden obstruction of airway(1).

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Effect of acupuncture on short-term memory and apoptosis after transient cerebral ischemia in gerbils

  • Choi, In-Ho;Lim, Hyung-Ho
    • 대한한의학회지
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    • 제39권4호
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    • pp.1-15
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    • 2018
  • Objectives: Cerebral ischemia results from a variety of causes that cerebral blood flow is reduced due to a transient or permanent occlusion of cerebral arteries. Reactive astrocytes and microglial activation plays an important role in the neuronal cell death during ischemic insult. Acupunctural treatment is effective for symptom improvement in cerebrovascular accident, including cerebral ischemia. Methods: In the present study, the effects of acupuncture at the ST40 acupoint on short-term memory and apoptosis in the hippocampal CA1 region following transient global cerebral ischemia were investigated using gerbils. Transient global ischemia was induced by occlusion of both common carotid arteries with aneurysm clips for 5 min. Acupuncture stimulation was conducted once daily for 7 consecutive days, starting one day after surgery. Results: In the present results, ischemia induction deteriorated short term memory, increased apoptosis, and induced reactive astrocyte and microglial activation. Acupuncture at ST40 acupoint ameliorated ischemia-induced short-term memory impairment by suppressing apoptosis in the hippocampus through down-regulation of reactive astrocytes and microglial activation. Conclusion: The present study suggests that acupuncture at the ST40 acupoint can be used for treatment of patients with cerebral stroke.

두경부 외상의 인터벤션 (Endovascular Treatment for Head and Neck Trauma)

  • 한재원;이재일;황보리
    • 대한영상의학회지
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    • 제84권4호
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    • pp.792-808
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    • 2023
  • 두경부 외상은 뇌를 포함한 중요 장기들의 손상을 동반하며 특히 혈관 손상의 경우 영구적 장애를 야기하거나 사망에 이르게 할 수 있어서 적시에 치료가 진행되어야 한다. 혈관내 인터벤션 치료에 대한 문헌적 근거 수준은 높지 않으나 기술의 발전에 힘입어서 혈관 손상의 치료에 대한 좋은 대안이 되고 있다. 고전적인 손상 혈관에 대한 색전술을 통한 치료 이외에도 개선된 혈관내 기구들을 통해 재건적 혈관 치료가 가능해지고 있어서 적절하게 시행될 경우 외상 환자의 예후 개선에 기여할 수 있다. 혈관 손상 치료의 방법은 외상 기전에 따라 상이하며 특정 임상적 상황에서 시술 방법이 달라질 수 있다. 이를 고려한 혈관내 인터벤션을 증례 중심으로 고찰해 보고자 한다.

독성 알코올 중독 환자에 대한 고찰 (Clinical Review of Toxic Alcohol Poisoning Cases in Korea)

  • 이누가;정성필;박인철;이경룡;김현진;김건배;조영순;권인호;김승환
    • 대한임상독성학회지
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    • 제10권1호
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    • pp.15-21
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    • 2012
  • Purpose: Toxic alcohols are responsible for accidental and suicide motivated poisonings, resulting in death or permanent sequelae for the afflicted patients. Major therapeutic modalities in these cases include treatment with alcohol dehydrogenase inhibitors and extracorporeal elimination. There have been a number of case reports of toxic alcohol intoxication in Korea. The purpose of this study was to review the clinical characteristics of patients suffering toxic alcohol intoxication. Methods: We retrospectively reviewed the medical records of patients who presented with toxic alcohol intoxication at 8 emergency departments (ED) from Jun 2005 to Nov 2011. Patients who ingested methanol, isopropyl alcohol, ethylene glycol, and other alcohols except ethanol, were included in this study. The clinical characteristics of these patients were analyzed to include anion and osmolar gap, and estimated concentration of alcohol in the body. Results: During the study period, 21 patients were identified who had ingested toxic alcohol (methanol; 12 patients, ethylene glycol; 9 patients). At ED arrival, the mean anion gap was $18.7{\pm}6.9$ and the osmolar gap was elevated in 13 patients. Oral and IV ethanol were administrated to 11 patients in order to inhibit alcohol dehydrogenase. Extracorporeal elimination procedures such as hemodialysis were performed in 9 patients. There were no fatalities, but the one patient suffered permanent blindness. Conclusion: This study found that ethylene glycol and methanol were the substances ingested which produced toxic alcohol intoxication. The patients presented with high anion gap metabolic acidosis and were typically treated with oral ethanol and hemodialysis.

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항암 치료를 받은 아동의 치아 발육 장애 (DEVELOPMENTAL DENTAL COMPLICATIONS AFTER ANTICANCER THERAPY IN CHILDREN)

  • 김민정;이형숙;김신;정태성
    • 대한소아치과학회지
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    • 제36권4호
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    • pp.607-612
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    • 2009
  • 소아기의 악성 종양은 질병으로 인한 소아 사망의 가장 흔한 원인이다. 이에 대한 대표적인 치료 방법으로 항암 화학 요법과 방사선 요법의 단독 사용 혹은 이들의 병용을 들 수 있다. 그러나 이러한 치료 방법은 다양한 구강 내 합병증을 동반한다. 성인과 달리 소아 환자는 항암치료 시기에 일부 영구치가 활발한 발육단계에 있으므로 발육중인 치아에 치과적 합병증이 예상된다. 치과적 합병증의 정도는 화학약물의 종류, 용량 및 방사선 조사 빈도와 치료 당시 환자의 나이에 따라 달라진다. 본 증례들에서는 특정 영구치의 발육단계에 있는 만 1-4세경에 종양의 치료를 위해 항암 화학 요법과 방사선 치료를 받은 어린이 3명을 대상으로 치료 내용과 치아 발육 상황을 검토해 보았다. 이환된 치아의 수나 그 정도에 차이는 있으나, 각각의 환자에서 영구치 치배의 선천 결손, 왜소치, 치근 저형성 등 발육장애 관련 소견이 관찰되었다. 항암치료를 받은 병력이 있는 소아에 있어서 항암치료 이후에 나타날 수 있는 일반적인 구강 합병증 이외에 발육시기 동안 치아에 미치는 영향을 고려하여, 공간 문제를 포함하여 향후 발생 할 수 있는 다앙한 문제점 예방을 위한 장기적인 관찰과 관리가 필요할 것으로 생각된다.

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Gap characteristics and natural regeneration in Mt. Makiling rainforest, the Philippines

  • Kim, Hyun-Ji;Kim, Tae-Geun;Kim, Eun-Hee;Castillo, Manuel L.;Cho, Do-Soon
    • Journal of Ecology and Environment
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    • 제34권2호
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    • pp.157-165
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    • 2011
  • This study was conducted to determine the characteristics of gaps and natural regeneration of trees on Mt. Makiling, the Philippines. Canopy gaps in or around two 1-ha permanent plots and on 3-km line transects were investigated. Most of the gaps studied were formed or affected by Typhoon Milenyo, which hit the study site in September 2006. The most frequent mode of gap maker death was snap-off, whereas uprooting was relatively less important. The most frequent gap maker was balobo (Diplodiscus paniculatus) followed by magabuyo (Celtis luzonica) and katmon (Dillenia philippinensis). In contrast, the most frequent gap filler was magabuyo (C. luzonica). At the sapling layer, the most important species was magabuyo (C. luzonica), but there was a high proportion of lianas and palms. Most of the gaps had leaf area index (LAI) values between 3 and 5. A clear trend of a decrease in gap size and an increase in LAI was observed for 2 years from 2007 to 2009. New seedlings emerged very abundantly during the same time period. The rapid changes in the gaps were partially due to the excellent capability of tropical trees to resprout after the crown or stem was damaged by the typhoon. This study on gap dynamics may contribute to a better understanding of the natural regeneration process of trees in tropical rainforests.

급성복통을 동반한 소아의 척추 경막외 농양 1예 (Acute Spinal Epidural Abscess Presenting with Abdominal Pain in a Child)

  • 정은영;이연경;김석헌;공병구;김광우;박영수;김동원
    • Pediatric Infection and Vaccine
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    • 제8권1호
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    • pp.107-113
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    • 2001
  • 저자들은 발열과 복통을 주소로 입원한 환아에서 연속적으로 요통 및 둔부 동통을 보여 실시한 자기 공명촬영상 요추 부위의 척추 경막외 농양을 진단하고 수술하였기에 문헌 고찰과 함께 보고하는 바이다.

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Chlorogenic acid alleviates the reduction of Akt and Bad phosphorylation and of phospho-Bad and 14-3-3 binding in an animal model of stroke

  • Murad-Ali, Shah;Ju-Bin, Kang;Myeong-Ok, Kim;Phil-Ok, Koh
    • Journal of Veterinary Science
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    • 제23권6호
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    • pp.84.1-84.15
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    • 2022
  • Background: Stroke is caused by disruption of blood supply and results in permanent disabilities as well as death. Chlorogenic acid is a phenolic compound found in various fruits and coffee and exerts antioxidant, anti-inflammatory, and anti-apoptotic effects. Objectives: The purpose of this study was to investigate whether chlorogenic acid regulates the PI3K-Akt-Bad signaling pathway in middle cerebral artery occlusion (MCAO)-induced damage. Methods: Chlorogenic acid (30 mg/kg) or vehicle was administered peritoneally to adult male rats 2 h after MCAO surgery, and animals were sacrificed 24 h after MCAO surgery. Neurobehavioral tests were performed, and brain tissues were isolated. The cerebral cortex was collected for Western blot and immunoprecipitation analyses. Results: MCAO damage caused severe neurobehavioral disorders and chlorogenic acid improved the neurological disorders. Chlorogenic acid alleviated the MCAO-induced histopathological changes and decreased the number of terminal deoxynucleotidyl transferase dUTP nick end labeling-positive cells. Furthermore, MCAO-induced damage reduced the expression of phospho-PDK1, phospho-Akt, and phospho-Bad, which was alleviated with administration of chlorogenic acid. The interaction between phospho-Bad and 14-3-3 levels was reduced in MCAO animals, which was attenuated by chlorogenic acid treatment. In addition, chlorogenic acid alleviated the increase of cytochrome c and caspase-3 expression caused by MCAO damage. Conclusions: The results of the present study showed that chlorogenic acid activates phospho-Akt and phospho-Bad and promotes the interaction between phospho-Bad and 14-3-3 during MCAO damage. In conclusion, chlorogenic acid exerts neuroprotective effects by activating the Akt-Bad signaling pathway and maintaining the interaction between phospho-Bad and 14-3-3 in ischemic stroke model.

초분, 한국 이중장제의 분석심리학적 고찰 : 부패와 뼈로의 환원을 중심으로 (CHOBUN, Understanding the Double Burial Custom in Korea from a Jungian Perspective : Focusing on Putrefaction and Reduction to Bones)

  • 조자현
    • 심성연구
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    • 제31권2호
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    • pp.113-150
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    • 2016
  • 초분은 살이 다 썩어 없어질 때까지 관에 넣은 시신을 짚으로 싸두는 초가 형태의 임시 무덤을 말한다. 모든 살이 다 없어지고 나면, 초분은 해체되고, 뼈만 추려 다시 묻는다. 이러한 방식의 초분은 따라서 처음 시신의 살을 처리하기 위한 임시 매장과 이후 남은 부분(뼈나 재)을 영구히 매장 하는 이중장제에 속한다. 초분은 사람이 잘 가지 않고, 집에서도 떨어져 있지만, 유족이 가서 돌볼 수 있는 곳을 택해 만들어지는데, 심리학적으로 이것은 지속적인 관심을 쏟을 수 있으면서도 고요히 격리될 수 있는 곳, 다시 말해 심리적인 재생이 일어나는 장소이다. 초분을 두는 기간, 일차장의 기간을 정하는데 가장 중요한 점은 뼈만 남길 때까지 기다려야 하는 기간이 얼마나 되는지, 그리하여 초분을 해체하였을 때 완전한 뼈 상태를 확인할 수 있는지와 관련된 것이다. 여기서 초분이 부패와 뼈로의 환원을 목표로 하고 있음을 알 수 있다. 부패와 새로운 생명의 탄생은 연금술 문헌에서 보듯 동시에 일어난다. 부패의 최종 목적은 육신을 영적 상태로 만들고, 그리하여 죽은 자를 다른 삶으로 들어갈 수 있게 만들어 주는 것이다. 그러기 위해서는 아주 불안정한 상태에서, 부패를 견뎌내고, 썩는 냄새가 모두 사라지는 것을 기다려야 한다. 썩히는 것은 그리하여 육화된 세계, 몸을 용해시켜 없애고, 그 핵심, 열매만을 남기는 것을 목표로 한다. 부패의 과정은 자기 스스로의 오염되고 끔찍한 측면을 받아들이는 태도이며, 무력하고 수동적인 자세를 취함으로써, 새로운 생명이 오게하는 것이다. 원형적인 세계, 무의식은 우리가 접근하려 할 때, 종종 위협적이고 공격적인, 더러운 무엇으로 경험된다. 개성화 과정에서, 우리가 우리 정신의 이 끔찍하고 오염된 부분들을 볼 수 있는 용기를 낼 때만이, 무의식은 우리에게 새로운 영적 각성과 새로운 삶의 감각이라는 축복을 주는데, 이것이 부패가 의미하는 것이다. 뼈와 골격은 생명의 부술 수 없는, 소멸되지 않는 본질적인 요소를 상징한다. 뼈는 재생을 위한 최소 단위이자, 재생의 바탕이 되며, 여기서 새로운 생명이 자라나게 된다. 뼈의 상태로 환원은 생명의 바로 그 원천으로 돌아감을, 자궁으로 다시 들어가 심리적으로 자신의 자아중심성을 버리고, 자기가 개성화의 전 과정을 이끌도록 허용하는 것이다. 앞으로의 발달을 위해, 골격 상태로의 환원의 어려운 과정을 겪는 것은, 자아의 죽음의 선언이며, 그 목적은 자신을 썩기 쉽고 덧없는 살과 피, 육신에서 해방시키고, 전체로서의 영적인 갱신, 생명의 불멸의 요소를 얻기 위함이다. 초분은 또한 식물의 순환에서 해마다 보이는 부패와 생명의 부활을 보여준다. 초분에서는 이러한 식물의 순환의 상징이 다른 일반적인 한국 전통 상장례에서보다 명확하고 강하게 드러나는데, 죽음에도 살아남는 생명의 부분을 식물의 상징을 통해 경험하게 한다. 초분과 관련된 식물은 죽음 후의 생명의 지속성, 심리적으로 말해, 자기의 존재를 말한다. 초분에서 드러나는 풍부한 식물의 이미지들은, 모든 것이 사라진 죽음의 상태 너머에 존재하는 생명의 존재와 관련되어 있으며, 심리학적으로 우리의 삶에 정신에 끝없는 에너지를 공급하는 영원히 존재하며 의식을 다시 태어나게 하고 새롭게 하는 자기의 존재를 이야기한다.

Role and Prognosis of Extracorporeal Life Support in Patients Who Develop Cardiac Arrest during or after Office-Based Cosmetic Surgery

  • Kwon, Seong Soon;Park, Byoung-Won;Lee, Min-Ho;Bang, Duk Won;Hyon, Min-Su;Chang, Won-Ho;Oh, Hong Chul;Park, Young Woo
    • Journal of Chest Surgery
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    • 제53권5호
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    • pp.277-284
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    • 2020
  • Background: Cardiac arrest during or after office-based cosmetic surgery is rare, and little is known about its prognosis. We assessed the clinical outcomes of patients who developed cardiac arrest during or after cosmetic surgery at office-based clinics. Methods: Between May 2009 and May 2016, 32 patients who developed cardiac arrest during or after treatment at cosmetic surgery clinics were consecutively enrolled. We compared clinical outcomes, including complications, between survivors (n=19) and non-survivors (n=13) and attempted to determine the prognostic factors of mortality. Results: All 32 of the patients were female, with a mean age of 30.40±11.87 years. Of the 32 patients, 13 (41%) died. Extracorporeal life support (ECLS) was applied in a greater percentage of non-survivors than survivors (92.3% vs. 47.4%, respectively; p=0.009). The mean duration of in-hospital cardiopulmonary resuscitation (CPR) was longer for the non-survivors than the survivors (31.55±33 minutes vs. 7.59±9.07 minutes, respectively; p=0.01). The mean Acute Physiology and Chronic Health Evaluation score was also higher among non-survivors than survivors (23.85±6.68 vs. 16.79±7.44, respectively; p=0.01). No predictor of death was identified in the patients for whom ECLS was applied. Of the 19 survivors, 10 (52.6%) had hypoxic brain damage, and 1 (5.3%) had permanent lower leg ischemia. Logistic regression analyses revealed that the estimated glomerular filtration rate was a predictor of mortality. Conclusion: Patients who developed cardiac arrest during or after cosmetic surgery at office-based clinics experienced poor prognoses, even though ECLS was applied in most cases. The survivors suffered serious complications. Careful monitoring of subjects and active CPR (when necessary) in cosmetic surgery clinics may be essential.