• Journal of Animal Science and Technology
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• v.45 no.1
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• pp.13-22
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• 2003

Growth Hormone (GH) gene is a member of gene family through the evolutionary process from a small common ancestral gene by a series of gene duplications. The role of the GH in growth and performance controls has been extensively studied in human, mice and livestock. Many researchers have considered GH as a strong candidate gene for evaluation of genetic polymorphisms that could be associated with economic traits in cattle. We report here a novel missense mutation within the exon 5 of the bovine Growth Hormone (bGH) gene. We could amplified 522 bp fragments from eight unrelated Hanwoo cattle by PCR, then, subsequently cloned and sequenced. An Msp I RFLP corresponding to a C to T transition was observed at position 2258 nt. From this result, we could predict a missense mutation (Arg to Trp) at codon 166 in a highly conserved region among many mammals. Codominant Mendelian segregation of the two alleles, Msp I (+) and Msp I (－), was observed in two full-sib F2 families (n = 32, African taurine Bos taurus ${\times}$ African zebu Bos indicus) and eight half-sib Hanwoo families. For the availability of genetic marker, we have performed PCR-RFLP with a large number of individual animals from 15 different cattle breeds (European and Asian taurines, and African indicines). Consideration of breed frequencies of Msp I (－) allele in relation to breed type and their geographic origins, shows higher frequencies in humped breeds or Asian cattle breeds than in humpless or European breeds. This result indicates that the missense mutation can be contributed the functional significance such as the signal transduction through the receptor binding, also may be used as a marker for selection of the economic traits in Hanwoo.

• Journal of Korean society of Dental Hygiene
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• v.10 no.6
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• pp.1129-1139
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• 2010

Objectives : The purpose of this study was to examine the toothbrushing practice behavior of preschool children by observing children's actual toothbrushing behavior and further to offer basic data available for being reflected in direction and goal establishment of the systematic and organized oral health education in consideration of individual characteristic. Methods : It targeted 225 preschool children from May 6, 2010 to June 8, and analyzed by having the survey results of totally 208 people, except 17 who are noncooperative with the observation survey. As for the collected materials, it carried out frequency analysis and $x^2$-test in order to grasp subjects' general characteristics and toothbrushing practice behaviors and to examine correlation, by using SPSS 12.0 for window. Results : 1. A grasp of toothbrush was indicated 47.1% for "proper" and 52.9% for "improper." The position of holding a toothbrush was indicated to be the highest with 59.6% for "the center in grip." 2. Toothpaste amount was indicated to be 49.0% for" tip in toothbrush, "followed by 38.9% for "half in toothbrush" and 12% for "every side of toothbrush" in order. Significant difference was shown according to age($x^2$=19.125. p<.05). 3. Average toothbrushing time per once was surveyed to be $106{\pm}56$ seconds. 4. As for a toothbrushing method by region, the labial and the baccal surface were indicated to be horizontal scrub with 63% and fones method 11.5%. Significant difference was shown according to gender($x^2$=10.275. p<.05). The anterior lingual surface wasn't washed with 72.6%. Significant difference was shown according to appearance of education($x^2$=6.056. p<.05). 5. A case of requiring exchange because of being widened toothbrush was indicated to be 59.2%. The toothbrush replacement in the highest ratio was needed in kindergarten teachers. Conclusions : The actual toothbrushing practice attitude of preschool children was surveyed to be not right as a whole such as toothbrushing time, toothbrushing method, toothpaste amount, and replacement of toothbrush. Accordingly, the oral health education will need to be performed in order for a change into positive attitude and for improvement in practice level. In addition, it is considered to be likely necessary for development in substantial oral health educational program available for enhancing knowledge level of oral health care in mothers and kindergarten teachers.

• Clinics in Shoulder and Elbow
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• v.2 no.2
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• pp.126-132
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• 1999

Purpose : To evaluate the functional and radiographic outcome of the modified Bosworth method in the surgical treatment of acute type V acromioclavicular joint dislocation. Materials and Methods: From June 1995 to May 1998, 20 patients were operated on for acute and complete acromioclavicular dislocation(Rockwood type V). The operative technique includes fixation of the coracoclavicular joint with Bosworth screw or 6.5mm cancellous screw and imbrication of trapezius and deltoid muscles. The average age was 34 years(range, 19 to 51 years). These 20 patients with an average follow-up of 18months, were evaluated clinically using the UCLA scoring system. Additional radiographical assessment was performed with stress radiographs. Results: Excellent or good clinical results were obtained in 95%(19 cases). And the average coracoclavicular interval ratio was decreased from 3.31(2.2-6.0) to 1.13(1-1.4) in stress radiographs. There were 4 cases of hetero­topic calcification postoperatively but there was no correlation with clinical result. Posttraumatic A-C joint arthritis was developed in one case. In that case, the distal clavicular resection was done under the arthroscopic technique. Conclusion: The severe displacement observed with type V injuries is incompatible with normal shoulder function if the shoulder is left in its displaced position. In type V injuries, significant damage to the deltoid and trapezius musculature and overlying fascia occurs, therefore open reduction and good fixation must be obtained with imbrication of trapezius and deltoid muscles. In our type V acute complete acromioclavicular dislocation, the modified Bosworth technique provides excellent results with a low complication rate.

• Journal of Life Science
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• v.26 no.1
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• pp.1-7
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• 2016

Fatness is one of the most important economic traits in pigs. The leptin receptor (LEPR) gene may be a potential candidate for the fatness quantitative trait locus (QTL) on porcine chromosome 6, due to its position and physiological role. Thus, this study was carried out to evaluate the associations between structural variants in the LEPR gene and economic traits in pigs. We obtained an approximately 114-kb sequence containing the complete genomic DNA of the porcine LEPR gene, using shotgun sequencing of a bacterial artificial chromosome clone. We report the complete genomic structure of the porcine LEPR gene. Dozens of transcription factor-binding sites were found in the 1.2 kb upstream region from the transcription start point. An association study was performed with 550 Duroc pigs for 24 single-nucleotide polymorphisms (SNPs), including 6 SNPs within exons and 18 SNPs within the putative 5‘ regulatory region of the porcine LEPR gene. Among them, one SNP (−790C/G) was significantly associated with backfat thickness and lean meat percentage, whereas the others, including two SNPs with missense polymorphisms, had no effect on any phenotype. These results suggest that SNP −790C/G may be a useful marker for genetic improvements of fatness and leanness in Duroc pigs.

• Journal of the Korea institute for structural maintenance and inspection
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• v.21 no.1
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• pp.91-99
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• 2017

The purpose of this paper is to evaluate the flexural performance of reinforced concrete (RC) beams repaired with polymer mortar. The repaired and non-repaired 13th beams which was fabricated by considering repair position, repair depth, and curing age of polymer mortar as test variables were tested under three point loading. All specimens repaired in compressive and tensile zone did not fail due to interfacial failure between polymer mortar and concrete but failed when the strain of repaired mortar exceeded the ultimate tensile strain of polymer mortar. Maximum load of specimens repaired in compressive zone was similar to that of non-repaired specimen, reference specimen. Additionally, their ductility index was higher than that of reference specimen. On the other hand, specimens repaired in tensile zone failed very brittlely and have a lower ductility index than reference specimen. Nonlinear analysis by using OpenSees was performed to predict the behavior of RC beam repaired with polymer mortar. Two dimension frame element was used to simplify an analysis model and fiber model was applied to consider the material non-linearity. It was confirmed from the analysis results that nonlinear analysis properly predicts the behavior of specimens repaired in compressive zone and overestimates the behavior of specimens repaired in tensile zone.

• Journal of the Korean Geotechnical Society
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• v.18 no.3
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• pp.51-59
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• 2002

This paper deals with development of a damage risk assessment system for adjacent buildings to under-passing tunnel face considering 3D-ground movement. The system consists of building and ground information module, monitoring data module, settlement evaluation module, and building damage risk assessment module. The major modules, settlement evaluation module and building damage assessment module, are based on settlement estimation model suggested by Attewell et al (1982) and the building damage assessment method by Mair et al. (1996). After estimating 3D-ground movements due to tunneling with settlement evaluation module, damage assessment far buildings is performed using building damage risk assessment module. The developed system has two major functions; 1) calculation of 3D-settlement with ground loss ($V_{s}$)or maximum settlement ($w_{max}$) and inflection point (i) using various empirical formulae, monitoring data, numerical results, and so on; 2) assessment of damage risk for adjacent buildings of arbitrary section with position change of tunnel face. The field data given by Boscadin and Cording (1989) leer the case of two-storied masonry building near the Metro tunnel in Washington D.C. was simulated to verify the applicability of the developed system.

• The Journal of Korean Academy of Prosthodontics
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• v.44 no.4
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• pp.394-404
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• 2006

Statement of problem: A conventional 3-unit fixed partial denture design with a pontic between two retainers is the most commonly used. However in cases where the mental nerve is in close proximity to the second premolar, a cantilever design can be considered. As such, logical and scientific evidence is lacking for the number and position of implants to be placed for partially edentulous patients, and no clear-cut set of treatment principles currently exist. Purpose : The purpose of this study was to evaluate prognosis of implant-supported fixed partial dentures and to compare changes in bone level which may rise due to the different factors. Material and method : The present study examined radiographical marginal bone loss in patients treated with implant-supported fixed partial dentures (87 prostheses supported by 227 implants) and evaluated the influence of the span of the pontic, type of the opposing dentition. Clinical complications were studied using a retrospective method. Within the limitation of this study. the following result were drawn Result, 1. Seven of a total of 227 implants restored with fixed prostheses failed, resulting in a 96.9% success rate. 2. Complications encountered during recall appointments included dissolution of temporary luting agent (17 cases), porcelain fracture (8 cases), loosened screws (5 cases), gingival recession (4 cases), and gingival enlargement (1 case). 3. Marginal bone loss, 1 year after prosthesis placement, was significant(P<0.05) in the group that underwent bone grafting, however no difference in annual resorption rate was observed afterwards. 4. Marginal bono loss, 1 year post-placement, was greater in cantilever-type prostheses than in centric pontic protheses (P<0.05). 5. Marginal bone loss was more pronounced in posterior regions compared to anterior regions (P<0.05). 6. The degree of marginal bone loss was proportional to the length of the pontic (P<0.05). Conclusion: The success rate of implant-supported fixed partial dentures, including marginal bone loss, was satisfactory in the present study. Factors influencing marginal bone loss included whether bone graft was performed, location of the pontic (s), location of the surgical area in the arch pontic span. Long-term evaluation is necessary for implant-supported fixed partial dentures, as are further studies on the relationship between functional load and the number of implants to be placed.

• Journal of the korean academy of Pediatric Dentistry
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• v.34 no.1
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• pp.162-168
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• 2007

Impaction of the maxillary central incisor may cause social, esthetic, and functional problems in children. There are various means of treatment for the inverted maxillary central incisor, such as extraction, surgical opening followed by orthodontic traction surgical repositioning or intra-alveolar autotransplantation prior to extraction. In this case, we surgically repositioned the inverted maxillary central incisor to normal semi-erupted position in a 5-year-old boy The developmental stage of the inverted tooth was Nolla's 6.5, which indicates formation of less than one third of the root. After surgical reposition, we did follow-up for 21 months, expecting spontaneous growth Unfortunately, poor prognosis was noted further root was not observed. Such failure seems to originate from possible injury on Hertwig's epithelial root sheath by surgical trauma. We performed surgical repositioning to retain the tooth instead of extraction. However, arrest of root development occurred which is one of the critical complications. In order to increase the success rate of the surgical reposition procedure, minimal surgical trauma is required as well as selection of adequate indication and decision of proper time of treatment considering the stage of root development.

• Journal of Dental Rehabilitation and Applied Science
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• v.26 no.2
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• pp.145-156
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• 2010

Loss of posterior support may cause overloading and excessive wear of remaining teeth. Moreover, the extrusion of antagonistic teeth leads to the destruction of the occlusal plane. The loss of vertical dimension of occlusion (VDO) also emerges clinically, which may bring the loss of esthetic appearance and function. These patients who suffer from the loss of posterior support, often require vigorous periodontal treatments (osteotomy, crown lengthening) and extensive oral rehabilitation. Sixty three years old female patient visited for the prosthetic treatment of the posterior edentulous area. She had no other systematic disease and parafuctional habits for prosthetic treatment. Intraoral and radiographic examinations were done. The evaluation of VDO and vertical dimension of rest position were evaluated for proper prosthetic procedures and diagnostic wax up was done. As a result of diagnosis, VDO was increased by 2 mm considering the loss of VDO and space for the prosthetic treatment. After the pretreatments, initial preparation of teeth and provisionalization were carried out. Six weeks later of provisionalizaion, final preparation and impression was performed. Using the duralay resin copings, jaw relation was registered. The master cast was mounted and definitive restoration was fabricated. After the evaluation of esthetic and function, pick up impression for clinical remounting was done. Lucia jig was made for new jaw relation and occlusal adjustment on the articulator. Definitive restoration was delivered and the patient was periodically recalled for additional occlusal adjustment. From this case, the satisfactory functional and esthetic results through full mouth rehabilitation with increase vertical dimension were achieved.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.11A
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• pp.1081-1091
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• 2005

Unlike conventional DVB-T transmission with the streaming method, DVB-H system based on the IPDC(IP Data Casting) method uses Time-slicing scheme to achieve the maximization of portability by reducing the power consumption of a receiver. To enhance the power efficiency of the receiver, Time-slicing scheme controls the receiver operation to perform only for corresponding burst in specific time slot. The additional power saving can also be achieved by reducing the required time for synchronization. In this paper, we propose a fast scattered pilot synchronization algorithm, which detects the pilot pattern of currently received OFDM symbol. The proposed scheme is based on the correlation between the adjacent subcarriers of potential scattered pilot position in two consecutively received OFDM symbols. Therefore, it can reduce the time for the scattered pilot synchronization within two symbols as com-pared with the conventional method used for DVB-T. And the proposed algorithm has better performance than the two schemes proposed by Nokia for DVB-H and the method using correlation with reference signal. Extensive com-puter simulation is performed based on ETSI EN300 744 ETSI and performance results show that the proposed algorithm has more efficient and stable operation than the conventional schemes.